1.The Change of Heart Rate Variability in Anxiety Disorder after Given Physical or Psychological Stress.
Min Kyung CHO ; Doo Heum PARK ; Jaehak YU ; Seung Ho RYU ; Ji Hyeon HA
Sleep Medicine and Psychophysiology 2014;21(2):69-73
OBJECTIVES: This study was designed to assess the change of heart rate variability (HRV) at resting, upright, and psychological stress in anxiety disorder patients. METHODS: HRV was measured at resting, upright, and psychological stress states in 60 anxiety disorder patients. We used visual analogue scale (VAS) score to assess tension and stress severity. Beck depression inventory (BDI) and state trait anxiety inventories I and II (STAI-I and II) were used to assess depression and anxiety severity. Differences between HRV indices were evaluated using paired t-tests. Gender difference analysis was accomplished with ANCOVA. RESULTS: SDNN (Standard deviation of normal RR intervals) and low frequency/high frequency (LF/HF) were significantly increased, while NN50, pNN50, and normalized HF (nHF) were significantly decreased in the upright position compared to resting state (p < 0.01). SDNN, root mean square of the differences of successive normal to normal intervals, and LF/HF were significantly increased, while nHF was significantly decreased in the psychological stress state compared to resting state (p < 0.01). SDNN, NN50, pNN50 were significantly lower in upright position compared to psychological stress and nVLF, nLF, nHF, and LF/HF showed no significant differences between them. CONCLUSION: The LF/HF ratio was significantly increased after both physical and psychological stress in anxiety disorder, but did not show a significant difference between these two stresses. Significant differences of SDNN, NN50, and pNN50 without any differences of nVLF, nLF, nHF, and LF/HF between two stresses might suggest that frequency domain analysis is more specific than time domain analysis.
Anxiety
;
Anxiety Disorders*
;
Autonomic Nervous System
;
Depression
;
Equipment and Supplies
;
Heart Rate*
;
Humans
;
Stress, Psychological*
2.Parosteal Ossifying Lipoma of Femur: A Case Report.
Jae Seok LEE ; Wan Hyung CHO ; Ji Yoong YU ; Min Suk KIM ; Jae Soo KOH
Korean Journal of Pathology 2007;41(2):123-126
Parosteal lipoma is a rare and generally asymptomatic benign tumor of mature adipose tissue that is located in direct apposition to the external surface of the bone. These tumors are occasionally associated with reactive changes in the underlying bone. The reactive bone formation is generally restricted to the base of the tumor, that is, near the periosteum. We recently experienced a case of parosteal lipoma in the proximal femur, which displayed exuberant bone and cartilage formation, and this led us to a misdiagnosis of chondroblastic osteosarcoma on the initial biopsy. We report here on this case with a special emphasis on making the differential diagnosis from osteosarcoma.
Adipose Tissue
;
Biopsy
;
Cartilage
;
Chondrocytes
;
Diagnosis, Differential
;
Diagnostic Errors
;
Femur*
;
Lipoma*
;
Osteogenesis
;
Osteosarcoma
;
Osteosarcoma, Juxtacortical
;
Periosteum
3.Isolated Adrenocorticotropic Hormone or Thyrotropin Deficiency Following Mild Traumatic Brain Injury: Three Cases with Long-Term Follow-Up.
Cho Ok BAEK ; Yu Ji KIM ; Ji Hye KIM ; Ji Hyun PARK
Korean Journal of Neurotrauma 2015;11(2):139-143
Few studies have examined the clinical features and long-term outcomes of isolated pituitary hormone deficiencies after traumatic brain injury (TBI). Such deficiencies typically present at time intervals after TBI, especially after mild injuries such as concussions, which makes their diagnosis difficult without careful history taking. It is necessary to improve diagnosis and prevent life threatening or morbid conditions such as those that may occur in deficiencies of adrenocorticotropic hormone (ACTH) or thyroid-stimulating hormone (as known as thyrotropin, TSH), the two most important pituitary hormones in hypopituitarism treatment. Here, we report two cases of isolated ACTH deficiency and one case of isolated TSH deficiency. These patients presented at different time points after concussion and underwent long-term follow-ups.
Adrenocorticotropic Hormone*
;
Brain Injuries*
;
Diagnosis
;
Follow-Up Studies*
;
Humans
;
Hypopituitarism
;
Pituitary Hormones
;
Thyrotropin*
4.A Case of Arteriovenous Hemangioma showing Darier's Sign.
Hee Joon YU ; Sang Jin KWON ; Ji Hyeung CHO ; Hong Yoon YANG ; Yong Wook PARK ; Se Jin JANG
Korean Journal of Dermatology 1997;35(1):209-213
We experienced a case of arteriovenous hemangioma showing Dariers sign on the forehead of a 43-year-old man. He presented with a single, 1 * 1.5cm sized, violaceous, asymptomatic nodule with a history of an intermittent wheal at the lesional site. This skin lesion showed Dariers sign clinically and proliferation of mast cells histopathologically with the punch biopsy specirnen suggesting urticaria pig- mentosa. Howerer, we could diagnose it as a arteriovenous hemangioma on complete excision, as the specimen showed arteriovenous proliferation with increased mast cells in a perivascular pattern. This case showed confusing clinical signs and showed the importance of complete excision for the diagnosis of a small skin tumor especially when a vascular proliferating tumor is suspected.
Adult
;
Biopsy
;
Diagnosis
;
Forehead
;
Hemangioma*
;
Humans
;
Mast Cells
;
Skin
;
Urticaria
5.A Case of Localized Trichorrhexis Nodosa Caused by Rubbing.
Da Ae YU ; Ji Young CHOI ; Min Woo KIM ; Ohsang KWON ; Hyun Sun YOON ; Soyun CHO ; Hyun Sun PARK
Korean Journal of Dermatology 2018;56(4):289-290
No abstract available.
Dermoscopy
;
Hair Diseases
;
Microscopy, Electron, Scanning
;
Pruritus
6.Synaptic Reorganization of Dentate Mossy Fibers and Expression of Calcium Binding Proteins in Hippocampal Sclerosis of Temporal Lobe Epilepsy.
Sang Pyo KIM ; Seung Pil KIM ; Seung Che CHO ; Young Rok CHO ; Ji Min JEON ; Yu Na KANG ; Kun Young KWON ; Eun Sook CHANG
Korean Journal of Pathology 1998;32(5):328-336
This study was designed to identify expression of calcium-binding proteins and synaptic reorganizations of dentate mossy fibers in hippocampal sclerosis of human temporal lobe epilepsy. Hippocampal neuronal density was quantitively analyzed in temporal lobe epilepsy group (n=50) to investigate the degree of hippocampal sclerosis and it was compared with that of autopsy control (n=3). To verify the distribution of calcium-binding proteins in neurons of epileptic hippocampi, the parvalbumin (PV)-immunoreactive and calbindin-D28K (CB)-immunoreactive neurons were quantitively analyzed in each area of Ammon's horn by immunohistochemical stain. Also, to clarify synaptic reorganizations of the dentate mossy fibers, a part of each hippocampus was examined under light microscopy and transmission electron microscopy using Timm sulphide silver method. In epileptic hippocampi, severity of hippocampal sclerosis (HS) was graded four, which consisted of 3 cases with no HS, 6 mild HS, 12 moderate HS, and 29 severe HS. The hippocampal neuronal loss was most prominent in CA1, followed by CA4 and CA2. Expression of calcium-binding proteins was more prevalent in CA2 of all groups. The proportion of PV-immunoreactive neurons in CA1 and CA4 significantly increased in the moderate and severe HS group, whereas the proportion of CB-immunoreactive neurons did not correlated with the severity of HS. Timm granules were noted in inner molecular supragranular layer of dentate gyrus of epileptic hippocampi and they tended to increase in proportion along with the severity of hippocampal sclerosis. Transmission electron microscopy showed that supragranular Timm granules corresponded to synaptic terminals of mossy fibers. These results suggest that parvalbumin appears to have more protective effect against neuronal loss and that mossy fiber synaptic reorganization seems to play a major role in pathogenesis of hippocampal sclerosis of human temporal lobe epilepsy.
Autopsy
;
Calbindin 1
;
Calcium*
;
Calcium-Binding Proteins*
;
Dentate Gyrus
;
Epilepsy, Temporal Lobe*
;
Hippocampus
;
Humans
;
Microscopy
;
Microscopy, Electron, Transmission
;
Nerve Fibers, Myelinated
;
Neurons
;
Presynaptic Terminals
;
Sclerosis*
;
Silver
;
Temporal Lobe*
7.Motherhood as Experienced by Women in a Prenatal and Early-Childhood Home Visitation Program, and Associated Factors
Ji Yun LEE ; Young-Ho KHANG ; Yu-Mi KIM ; Kyung Ja JUNE ; Sung-Hyun CHO ; Hong-Jun CHO
Journal of the Korean Society of Maternal and Child Health 2024;28(1):22-31
Purpose:
This study is intended to examine the difficulties facing mothers of young children (early childhood) and to understand the associated factors.Method: We analyzed 1,003 data items of women with children under age 2 who participated in a prenatal and early-childhood home visitation program in Seoul from 2016 to 2019. For our research, we used self-administered registration and service monitoring data. The difficulties the women faced as mothers were measured using the “Being a Mother Scale” (BaM-13). This analysis considered covariates including maternal and infant ages, their number of children, economic conditions, presence of disabilities, single motherhood, multicultural migration background, employment status, unintended pregnancy, instrumental and emotional support, and depression scores.
Results:
The average score for being a mother was 14.45 (standard deviation=6.61), and higher scores were recorded for women with spouses, Korean women (as opposed to multicultural immigrant women), women whose pregnancies were unplanned, women without instrumental support, and severely depressed women.
Conclusion
Motherhood poses great difficulties to women with children under age two. To help women transition from motherhood, it is important to understand their situations in relation to their social and psychological characteristics, as well as the cultural, social, and contextual perspectives they bring to motherhood.
8.Relationship between Nocturnal Polyuria and Antidiuretic Hormone in Chronic Spinal Cord Injury.
Ji Yeon YU ; Kyeong Ho SHIN ; Jeong Tae KIM ; Ji Hyae BAE ; Yeong Ok PARK ; Young Jin CHO
Journal of the Korean Academy of Rehabilitation Medicine 1999;23(5):961-967
OBJECTIVE: To delineate the role of antidiuretic hormone (ADH) in relation to nocturnal polyuria, and to identify the factors influencing on the diurnal antidiuretic hormone level. METHOD: The ADH was measured by radioimmuoassay at daytime (2:00 PM) and at nighttime (2:00 AM) with nocturnal polyuria group (11) and without nocturnal polyuria group (8). Urine volume, serum osmolarity, urine osmolarity, and blood pressure were also measured at the same time. RESULTS: 1) The ADH at 2:00 AM did not increase in nocturnal polyuria group, although it increased in no-symptom group. 2) There was a statistically significant correlation between wheelchair ambulation time and daytime ADH level. 3) The difference of ADH level between daytime and nighttime showed decrease in orthostatic hypotension group. CONCLUSION: There was relationship between nocturnal polyuria and diurnal variation of ADH level. The ADH concentration seems to be influenced by the postural factors and sympathetic factors.
Blood Pressure
;
Hypotension, Orthostatic
;
Osmolar Concentration
;
Polyuria*
;
Spinal Cord Injuries*
;
Spinal Cord*
;
Walking
;
Wheelchairs
9.Herpes zoster after COVID-19 vaccination, aspect of pain medicine: a retrospective, single-center study
Ji Hye LEE ; Yu Yil KIM ; Hyun Joo HEO ; Ji Hun PARK ; Hyung Gu CHO ; Geonbo KIM
Anesthesia and Pain Medicine 2023;18(1):57-64
Herpes zoster (HZ) is one of the most common cutaneous adverse reactionsassociated with the coronavirus disease 2019 (COVID-19) vaccine and has been widely reported. This study aimed to evaluate HZ following COVID-19 vaccination from the viewpointof pain management.Methods: A retrospective study was conducted on 42 patients with HZ who visited the painclinic between August 2021 and October 2021. Medical records were reviewed to comparepain severity, treatment methods, treatment duration, and incidence rate of postherpeticneuralgia (PHN) in patients who received COVID-19 vaccination within 6 weeks prior to developing symptoms compared with other patients with HZ.Results: Fourteen patients developed HZ within 6 weeks after vaccination and were significantly younger than the other HZ groups. There were no significant differences in the frequency of prodromal pain, location of pain, pain severity, treatment methods, treatmentduration, or incidence of PHN compared with the other HZ groups.Conclusions: COVID-19 vaccination-related HZ showed clinical features similar to those ofthe other HZ.
10.Stomach and Colon Metastasis from Breast Cancer.
Hyun A YU ; Eun Young KIM ; Min Ji SEO ; Eun CHUNG ; Min Jung CHO ; Hyun Jin OH ; Ji Hye JANG ; Ji Chan PARK ; Jung Uee LEE ; Suk Young PARK
The Ewha Medical Journal 2014;37(2):98-104
Gastric metastasis from breast cancer is rare and only six cases have been reported in Korea. Colon metastasis is more rare than gastric metastasis. We report a 63-year-old woman with gastric and colon metastases of invasive lobular carcinoma of breast. She was diagnosed as right breast cancer, received right modified radical mastectomy 10 years ago and has been treated with chemotherapy and hormone therapy. Investigating for melena and a small caliber of stool, we found gastric and colon metastases. The diagnosis of metastatic breast cancer was made through gross pathologic and immunohistochemistry staining. We report a case with gastric and colon metastases from breast cancer and a review of the associated six case reports in Korea.
Breast
;
Breast Neoplasms*
;
Carcinoma, Lobular
;
Colon*
;
Diagnosis
;
Drug Therapy
;
Female
;
Humans
;
Immunohistochemistry
;
Korea
;
Mastectomy, Modified Radical
;
Melena
;
Middle Aged
;
Neoplasm Metastasis*
;
Stomach*