Objective To evaluate the clinical effectiveness of heat-sensitive moxibustion for knee osteoarthritis ( KOA) by systematic evaluation and Meta analysis methods. Methods Electronic information retrieval combined manual retrieval methods were used for collecting clinical randomized control trial of heat-sensitive moxibustion for KOA. The systematic evaluation was conducted by two individual researcher following the principles of Cochrane Review Handbook 5.1, and RevMan5.0 software was applied for the statistical analysis. Results Fifteen randomized controlled trials (RCT) were enrolled into the analysis, which involved 1228 cases. The results of systematic evaluation showed that the quality of most of the enrolled RCT were not so high. The results of Meta analysis were as follows: ( 1) Between heat-sensitive moxibustion and traditional moxibustion, the weighted mean difference (WMD) and 95%confidence index (CI) were-1.76, [-2.33, -1.18] for visual analog scale ( VAS) scores ( P<0.001) , were -2.36, [-3.42, -1.30] for the scores of guiding principle of clinical research on new drugs ( GPCRND) for KOA ( GPCRND-KOA) ( P<0.001) , and were 13.61, [7.60, -19.61]for Lysholm knee joint function scores (P<0.001), respectively; (2) Between heat-sensitive moxibustion and acupuncture, WMD and 95%CI were 6.19, [ 0.01, 11.37] for Lysholm scores ( P<0.05);(3) Between heat-sensitive moxibustion and warm-needling acupuncture, WMD and 95%CI were -10.14, [-17.47, -2.81] for the Western Ontario and McMaster Universities ( WOMAC) osteoarthritis index scores ( P<0.05). Conclusion It is indicated that heat-sensitive moxibustion shows certain therapeutic effect for knee osteoarthritis, better than traditional moxibustion.

Adolescent ; Adult ; Child ; Dexamethasone ; administration & dosage ; Drug Therapy, Combination ; Drugs, Chinese Herbal ; administration & dosage ; Female ; Humans ; Male ; Middle Aged ; Phytotherapy ; Rhinitis, Allergic, Perennial ; therapy ; Volatilization

Objective: To explore children's self-concept differences in age,sex and area during early adolescence.Methods: 533 children aged from 8 to 13 years were surveyed with the Piers-Harris Children's Self-Concept Scale.Results: ①Children's self-concept as well as its six components developed unequally as age grew.Significant differences existed in the Intellectual and School Status Subscale and the Physical Appearance and Attributes Subscale among children of different ages.②Girls did significantly better than boys in Behavior,Intellectual and School Status and Popularity subscales.③Children in urban areas scored significantly higher than those from the countryside in Physical Appearance and Attributes Subscale.Conclusion: There is certain uniqueness in children's general self-concept as well as its different components,according to children's ages,sexes and areas during early adolescence.

Objective To establish a method for the determination of phthalates in water by solid phase extraction-gas chromatography-mass spectrometry(SPE-GC-MS).Methods The water samples were extracted and enriched by solid phasse extraction,using 10%methanol-methyl tert-butyl ether as eluant,dimethylphthalate(DMP),diethylphthalate(DEP),dibutylphthalate (DBP)and diethylhexylphthalate(DEHP)were determined by gas chromatography-mass spectrometry with selected ion monitoring mode(SIM).Results The concentration had a good linear range in the range of 0.00~10.00?g/ml,the correlation coefficient was above 0.998.The detection limit of DMP,DEP,DBP and DEHP were 2.7,2.1,1.6 and 2.5 ng/L respectively,the average recovery rate and the RSD of the method were 78.0%～102.5%and 3.3%～7.8%respectively.Conclusion This method,with small amount of solvent,is simple,fast,accurate and is applicable to the determination of phthalates in water.

The incidence of breast cancer has markedly increased in recent years.Breast cancer has become a major cause of death of adult females.Many studies have shown that glucose metabolism disorders and its connected factors have been closely related to occurrence and development of breast cancer.Regulation of glucose metabolism and related factors may become an important way in prevention and treatment of breast cancer.

Triptophenolide (TN) is a colorless crystalline plate isolated from ethyl acetate extracts of Tripterygium wilfordii. It can obviously inhibit the edema caused by xylol and mixture croton oil; and decrease the concentration of Vitamin C in the adrenal gland of mice.TN can remarkably inhibit the delayed type hypersensitivity (DTH) reaction induced by DNCB and BSA; and diminished the peripheral blood ANAE+lymphocytes in rats and micc.Moreover, TN can dramatically increase the amount of total serum complement and significautly decrcase the serum antibody products (1gG ) of rats and mice. The phagocytosis of perioneal exudate macrophages in mice present double effects in vitro. TN can promote the phagocytosis of macrophages at the small dosage, but at larger dosage, it showed inhibition.The results mentioned above showed that triptophenolide may be one of the main effective component of T.wilfordii for treating auto-immune diseases.

SUMMARY Lymphoma is a systemic disease. It is not uncommon to be found involved in digestive or central nervous system. However, lymphoma involved in these two systems at the same time is rare. The clinical feature of a case of lymphoma with gastrointestinal bleeding and limbs weakness was investigated and the literature was reviewed. The patient came to our hospital with melena and hematemesis. She was diagnosed as gastric ulcer by gastroscopy and biopsy showed lymphoma. Two days after she came to hospital, the patient presented with progressing limbs weakness. Magnetic resonance imaging (MRI) showed irregular abnormal signals in T2-T4 vertebra, which was enhanced obviously. A strip abnormal signal could be seen in spinal cord and involved in neighboring centrum and ribbing. The lesion extended to paravertebral tissue. The final diagnosis was lymphoma involved in stomach and spinal cord. Diseases presented with both upper digestive tract bleeding and symptoms of central nervous system were rare, including malignancies, virus infection and some therapy. Lymphoma was one of the causes. On the other hand, spinal cord ischemia might occur after gastrointestinal bleeding. Thus, doctors should examine the patients carefully to diagnose these diseases.

Objective: To observe the role of nutritional support in treatment of chylous leakage after thyroid carcinoma operation.Methods: The parenteral nutrition combined with somatostatin and re-operation was used in treatment of 2 cases of chylous leakage after thyroid carcinoma operation.Fluid volume from neck drainage catheter and plasma albumin concentration were determined in 2 cases.Results: Fluid volume from neck drainage catheter rapidly reduced in 2 cases after using somatostatin and parenteral nutrition.1case was cured after conservative treatment.1 case was cured after re-operation combined with nutrition support.Conclusion: By using nutrition support,fluid volume from neck drainage catheter can be obviously reduced and serum albumin or nutritional state improved in chylous leakage patients after thyroid carcinoma operation.

OBJECTIVE To explore the incidence of the nosocomial infection in patients with mental diseases,(analyze) the correlative factors and then reduce the incidence.(METHODS) By using the retrospective method,the(inpatient) cases in psychiatry department from Jan 2000 to Dec 2004 were surveyed and statistically analyzed.(RESULTS) There were 313 cases of nosocomial infection from 9 089 inpatients with mental diseases.The infection rate was(3.44%.) The total rate had been dropped year by year.The major sites of the infection were the(upper)(respiratory) tract(34.82%),the gastrointestinal tract(20.45%) and the urinary system(18.53%).The(infection) rate in ladies patient area(3.83%) was significantly higher than that of gentlemen patient area(3.07%)(P

Objective To explore the influence of organizational climate and job burnout on turnover tendency among contract nurses, and establish a model of this influence. Methods Totally 450 nurses were selected and investigated with Organizational Climate Questionnaire(OCQ), Maslach job burnout inventory(MBI) and Turnover Intention Scale(TIS). Results The total score of OCQ was 2.71 ± 0.58, the emotional exhaustion was 25.99 ± 13.89, the depersonalization was 10.21 ± 5.37,the personal accomplishment was 21.92 ± 9.27, and the score of TIS was 2.66 ± 0.94. Emotional exhaustion and depersonalization were significantly and negatively correlated to OCQ(r=-0.26,-0.22 ,P<0.01),and positively correlated to TIS(r=0.27,0.25,P<0.01). The personal accomplishment was positively correlated to OCQ(r=0.26,P<0.01), and negatively correlated to TIS(r=- 0.26,P<0.01).OCQ was negatively correlated to TIS(r=-0.37,P<0.01).Multiple linear regression analysis showed that OCQ and personal accomplishment could negatively predict nurses′ turnover tendency(β=-0.43,-0.14,P<0.01), and emotional exhaustion could negatively predict nurses′ turnover tendency(β=-0.10,P<0.01). The path analysis showed organizational climate negatively influenced nurses′ turnover tendency via job burnout, and the value of mediating effect was 23.8%(-0.10/-0.42). Conclusions Turnover tendency is significantly correlated with organizational climate and job burnout among contract nurses. The relationship between organizational climate and nurses′ turnover tendency among contract nurses is mediated in part by job burnout.