Three cases of sclerosing stromal tumor of the ovary are presented. All three patients were nulliparous young wemen of 23~25 years of age, presenting with menstrual irregularity for 6 months to 4 years. Grossly the tumors ranged in size from 8 to 22cm in greatest diameter, showing gray white to yellow solid or predominantly cystic tissue with serous fluid. The common microscopic finding was that of cellular areas admixed with densel fibrous and/or edematous tissue, presenting pseudolobular appearance. Two types of tumor cells were rounded cells with clear vacuolated cytoplasm and less numerous spindle shaped cells. Postoperative course was uneventful and menstrual irregularity disappeared postoperatively. In case 2, the patient got pregnant after 1 year and 4 months. This clinical course suggests that sclerosing stromal tumor of the ovary may be endocrinologically active.
Pregnancy ; Female ; Humans

No abstract available.
Diagnosis*

A case of telangiectatic osteosarcoma of the proximal tibia of left leg in 19-year-old man was reported. Radiologically the tumor was aneccentric blow-out osteolytic lesion simulating aneurysmal bone cyst. Pathologically the tumor presented multiple blood filled cystic spaces and anaplastic spindle cells of osteoclastic type and focal osteoid deposition. The patient died 8 months after he underwent high above knee amputation followed by adjuvant chemotherapy. Distinct clinicopathologic finding of telangiectatic osteosarcoma was described with special emphasis on differential diagnosis.
Amputation ; Aneurysm ; Bone Cysts ; Chemotherapy, Adjuvant ; Diagnosis, Differential ; Humans ; Knee ; Leg ; Osteoclasts ; Osteosarcoma ; Tibia ; Young Adult

BACKGROUND: The present study was performed to elicit what effect nalbuphine would have on isoflurane MAC (minimum alveolar concentration) in the patients undergoing lower abdominal surgery. METHODS: Sixty-two women were randomly allocated to one of five study groups to receive an intravenous injection of no nalbuphine (group I), 0.25 mg/kg (group II), 0.5 mg/kg (group III), 1.0 mg/kg (group IV), 1.5 mg/kg (group V). Anesthesia and tracheal intubation were induced with propofol 2 mg/kg, succinylcholine 1 mg/kg. Patients were inhaled at a preset end-tidal concentration of isoflurane, which was maintained for 20 min. Response to skin incision, movement or no movement, was determined 30 minutes after nalbuphine injection. The isoflurane concentration of the next patient in the same group moved up or down in steps of 0.1~0.3%, according to the previous patient's response. MAC was determined using the "up-down" method and logistic regression. RESULTS: The MAC's of isoflurane were 1.09 vol% end-tidal in the control group, 0.89 vol% in group II, 0.65 vol% in group III, 0.55 vol% in group IV, and 0.51 vol% in group V. CONCLUSIONS: It would be suggested that nalbuphine dose-dependently reduce the isoflurane MAC, and have ceiling effect on the reduction of isoflurane MAC.
Anesthesia ; Female ; Humans ; Injections, Intravenous ; Intubation ; Isoflurane* ; Logistic Models ; Nalbuphine* ; Propofol ; Skin ; Succinylcholine

OBJECTIVE: This study aimed to propose clinical guidelines for placing miniscrew implants using the results obtained from 3-dimensional analysis of maxillary anterior interdental alveolar bone by cone-beam computed tomography (CBCT). METHODS: By using CBCT data from 52 adult patients (17 men and 35 women; mean age, 27.9 years), alveolar bone were measured in 3 regions: between the maxillary central incisors (U1-U1), between the maxillary central incisor and maxillary lateral incisor (U1-U2), and between the maxillary lateral incisor and the canine (U2-U3). Cortical bone thickness, labio-palatal thickness, and interdental root distance were measured at 4 mm, 6 mm, and 8 mm apical to the interdental cementoenamel junction (ICEJ). RESULTS: The cortical bone thickness significantly increased from the U1-U1 region to the U2-U3 region (p < 0.05). The labio-palatal thickness was significantly less in the U1-U1 region (p < 0.05), and the interdental root distance was significantly less in the U1-U2 region (p < 0.05). CONCLUSIONS: The results of this study suggest that the interdental root regions U2-U3 and U1-U1 are the best sites for placing miniscrew implants into maxillary anterior alveolar bone.
Adult ; Cone-Beam Computed Tomography ; Female ; Humans ; Incisor ; Male ; Tooth Cervix

In order to evaluate contamination of the topical eye drugs, 112(36 kinds) medications used over 1 month by the patients and 80(25 kinds) medications used at OPD(outpatient department) were studied by culturing the caps, the tips and the contents. Coagulase-negative staphylococcus was mainly isolated from the caps and the tips(p<0.05). But the other gram-positive bacteria, gram-negative bacteria and fungi were isolated from all medication sites. The most frequent site of contamination was the tips of the medications. Frequency of contamination based on detail of medications and preservatives of medications was not statistically significant(p>0.05). The medications used by the patients for a long time in comparison with the medications used at OPD were significantly more likely to be contaminated(p<0.0001). Therefore, we think that the topical eye durgs should be used with proper instillation and storage for a short period because of increase risk of contamination.
Fungi ; Gram-Negative Bacteria ; Gram-Positive Bacteria ; Humans ; Staphylococcus

In vivo 31P magnetic resonance spectroscopy (MRS) was used to evaluate the effect of nimodipine on changes of [H] (pH) and the ratio of [PCr]/[Pi] in cats subjected to an incomplete global cerebral ischemia-reperfusion under the pretreated condition of hyperglycemia. Animals were subjected to a transient (18 minutes) incomplete global cerebral ischemia; the systemic arterial hypotension was induced, and immediately followed by the bilateral carotid artery ligation. Twenty cats were divided into 3 groups; for group 1 (control), 7 cats were employed for a control group; for group 2 (hyperglycemia), 7 cats were a hyperglycemia group with infusion of 50% glucose prior to ischemia; for group 3 (Nimodipine), 6 cats were infused with 50% glucose prior to ischemia, and nimodipine after ischemia. The time course of changes in pH and [PCr]/ [Pi] was monitored before, during and after ischemia. The pH decreased immediately after ischemia in all three groups. After the reperfusion was made, the values of the pH did not retum to the baseline value for the group 2 (hyperglycemia) and 3 (nimodipine), in contrary to the group 1 (control). The ratio of [PCr]/[Pi] was dropped to 20% of the baseline value after ischemia in all three groups. The value was recovered progres- sively during reperfusion period for group 1 (control), whereas for group 2 (hyperglycemia) and group 3 (Nimodipine) the values were remained depressed. The results suggest that the condition of hyperglycemia induced by the infusion of 50% glucose prior to the incomplete global cerebral ischemia-reperfusion, may deteriorate the cerebral ischemia and the infusion of nimodipine during ischemia-reperfusion has no beneficial effects to improve the cerebral acidosis and the metabolic recovery.
Acidosis ; Animals ; Brain Ischemia ; Carotid Arteries ; Cats* ; Glucose ; Hydrogen-Ion Concentration ; Hyperglycemia* ; Hypotension ; Ischemia ; Ligation ; Magnetic Resonance Spectroscopy ; Nimodipine* ; Reperfusion

In vivo 31P magnetic resonance spectroscopy (MRS) was used to evaluate the effect of nimodipine on changes of [H] (pH) and the ratio of [PCr]/[Pi] in cats subjected to an incomplete global cerebral ischemia-reperfusion under the pretreated condition of hyperglycemia. Animals were subjected to a transient (18 minutes) incomplete global cerebral ischemia; the systemic arterial hypotension was induced, and immediately followed by the bilateral carotid artery ligation. Twenty cats were divided into 3 groups; for group 1 (control), 7 cats were employed for a control group; for group 2 (hyperglycemia), 7 cats were a hyperglycemia group with infusion of 50% glucose prior to ischemia; for group 3 (Nimodipine), 6 cats were infused with 50% glucose prior to ischemia, and nimodipine after ischemia. The time course of changes in pH and [PCr]/ [Pi] was monitored before, during and after ischemia. The pH decreased immediately after ischemia in all three groups. After the reperfusion was made, the values of the pH did not retum to the baseline value for the group 2 (hyperglycemia) and 3 (nimodipine), in contrary to the group 1 (control). The ratio of [PCr]/[Pi] was dropped to 20% of the baseline value after ischemia in all three groups. The value was recovered progres- sively during reperfusion period for group 1 (control), whereas for group 2 (hyperglycemia) and group 3 (Nimodipine) the values were remained depressed. The results suggest that the condition of hyperglycemia induced by the infusion of 50% glucose prior to the incomplete global cerebral ischemia-reperfusion, may deteriorate the cerebral ischemia and the infusion of nimodipine during ischemia-reperfusion has no beneficial effects to improve the cerebral acidosis and the metabolic recovery.
Acidosis ; Animals ; Brain Ischemia ; Carotid Arteries ; Cats* ; Glucose ; Hydrogen-Ion Concentration ; Hyperglycemia* ; Hypotension ; Ischemia ; Ligation ; Magnetic Resonance Spectroscopy ; Nimodipine* ; Reperfusion

PURPOSE: To report two case of oculomotor palsy accompanied by herpes zoster ophthalmicus (HZO). CASE SUMMARY: Two patients with HZO who were suffering from skin lesions, facial pain, and medicated with an antiviral agent from the dermatologic department, were diagnosed with oculomotor palsy. They presented with ptosis, dilated pupils, and ophthalmoplegia after 10 days, and 4 days after began developing skin lesions. They were diagnosed with HZO-induced oculomotor palsy and the ophthalmoplegia improved in all cases. CONCLUSIONS: Oculomotor nerve palsy rarely occurrs in HZO patients and is usually followed by skin lesions. We recommend examinations for functions of extraocular motility, ptosis, and pupil to diagnose and treat the HZO-induced oculomotor nerve palsy even if consulted with the dermatologic department or only showing mild conjunctivitis, episcleritis, or keratitis.
Conjunctivitis ; Facial Pain ; Herpes Zoster Ophthalmicus* ; Herpes Zoster* ; Humans ; Keratitis ; Oculomotor Nerve Diseases* ; Oculomotor Nerve* ; Ophthalmoplegia ; Paralysis ; Pupil ; Scleritis ; Skin

No abstract available.
Anencephaly* ; Humans ; Pregnancy, Twin* ; Twins*