1.A Case of Mitral Valve Stenosis and Tricuspid Valve Regurgitation Accompanied by Metal Allergy Treated with Mitral Valve Replacement and Tricuspid Valve Annuloplasty
Yu Shomura ; Yukikatsu Okada ; Michihiro Nasu ; Hiroshi Fujiwara ; Shigeru Komori ; Mikito Inouchi ; Yasuhisa Ozu ; Takashi Hashimoto
Japanese Journal of Cardiovascular Surgery 2009;38(6):385-388
A 66-year-old woman who had percutaneous mitral valve commissurotomy 12 years before was admitted complaining of dyspnea on effort. Echocardiography showed severe mitral stenosis and regurgitation, and moderate tricuspid regurgitation associated with atrial fibrillation. Based on her past history we suspected allergy to metal, and skin patch tests showed a positive reaction to zinc, manganese, nickel, cobalt, dichromate, stainless steel, titanium alloys, and nickel-chromium-cobalt alloys. We selected an artificial organ which would not cause an allergic reaction. The St. Jude Medical standard cuff mechanical valve was the only compatible prosthetic valve. Anterolateral right thoracotomy, instead of median sternotomy, was selected. Mitral valve replacement with a 27-mm St. Jude Medical standard cuff mechanical valve and tricuspid valve annuloplasty with a 27-mm Duran flexible band were performed. Her postoperative course was uneventful. She is doing well without any allergic symptom 18 months after the surgery.
2.Morphological changes of roof of subacromial bursa in patients with rotator cuff tear.
Jin-yu ZHU ; Qing-sheng ZHU ; Takashi HASHIMOTO ; Katsuya NOBUHARA
Chinese Journal of Traumatology 2004;7(4):205-209
OBJECTIVETo investigate the morphological changes of the roof of the subacromial bursa (SAB) and its involvement extent after rotator cuff tear.
METHODSIn the experimental group, the roof of SAB was obtained from 30 cases of rotator cuff tear both at the tear site and a site 2.5-3.0 cm distal to the tear site during rotator cuff repair. In the control group, the roof of SAB was obtained from the exposed site of recurrently dislocated shoulder or fractured humeral shaft of 8 cases. The specimens were stained with hematoxylin and eosin and observed under a transmission electron microscope. The cell number was quantitated through counting the blue-stained nucleus in SAB with a computer image analysis system.
RESULTSThe number of cells increased significantly in the roof of SAB in the experimental group compared with that of the control group. However, no difference of the bursal reaction was found among the type of rotator cuff tear, the bursa thickness and the presence of fluid in the bursa. The great majority of cells were type B cells observed under the transmission electron microscope.
CONCLUSIONSThe increase in cell number in the roof of SAB in the experimental group is a reactive increase rather than an inflammatory process and the involvement of SAB is not limited in extent. The change of the roof of SAB is a secondary reaction to the rotator cuff tear.
Adult ; Aged ; Analysis of Variance ; Bursa, Synovial ; pathology ; Female ; Humans ; Inflammation ; Male ; Microscopy, Electron ; Middle Aged ; Rotator Cuff Injuries
3.How do patients and providers react to different incentives in the Chinese multiple health security systems?
Chun-Yu ZHANG ; Hideki HASHIMOTO
Chinese Medical Journal 2015;128(5):632-637
BACKGROUNDChina has achieved universal health insurance coverage. This study examined how patients and hospitals react to the different designs of the plans and to monitoring of patients by the local authority in the Chinese multiple health security schemes.
METHODSThe sample for analysis consisted of 1006 orthopedic inpatients who were admitted between January and December 2011 at a tertiary teaching hospital located in Beijing. We conducted general linear regression analyses to investigate whether medical expenditure and length of stay differed according to the different incentives.
RESULTSPatients under plans with lower copayment rates consumed significantly more medication compared with those under plans with higher copayment rates. Under plans with an annual ceiling for insurance coverage, patients spent significantly more in the second half of the year than in the first half of the year. The length of stay was shorter among patients when there were government monitoring and a penalty to the hospital service provider.
CONCLUSIONSOur results indicate that the different designs and monitoring of the health security systems in China cause opportunistic behavior by patients and providers. Reformation is necessary to reduce those incentives, and improve equity and efficiency in healthcare use.
China ; Female ; Health Personnel ; statistics & numerical data ; Humans ; Insurance, Health ; statistics & numerical data ; Male ; Motivation ; Patients ; statistics & numerical data
4.Open Abdominal Management Among Non-Trauma Patients: The Appropriate Duration and a New Clinical Index
Koichi INUKAI ; Akihiro USUI ; Yu HASHIMOTO ; Fumitaka KATO ; Koji AMANO ; Hiroyuki KAYATA ; Nobutaka MUKAI ; Naoki SHINYAMA
Journal of Acute Care Surgery 2022;12(3):97-102
Purpose:
Despite widespread adoption of open abdominal management (OAM), there is currently no threshold criterion for OAM duration for non-trauma patients. Moreover, there is a positive relationship between morbidity and the duration of OAM, but an uncertain relationship with patients’ age. Therefore, a novel clinical index for the duration of open abdominal management (IDOM) was developed based on the patient’s age and risk of severe complications following OAM to indicate the maximum tolerable number of days of OAM based on the individual’s age. The utility of this new index was evaluated.
Methods:
This retrospective study included 65 non-trauma patients managed with an open abdomen (OA) from August 2015 to August 2018. The IDOM was developed based on the patient’s age. The result indicated the maximum number of OA days. Patients’ demographic and operative variables were examined and patient data was assigned to one of two groups according to whether the actual number of OA days was above or below the calculated IDOM. Prevalence of complications between these groups was compared. Measures of validity were employed to assess the utility of the IDOM for patient complications.
Results:
Sixty-five patients were included. The above-the calculated IDOM group exhibited a significantly longer OA and higher rates of wound complications and postoperative respiratory complications compared with the below the calculated IDOM group. The IDOM predicted the incidence of OA-related complications with a sensitivity of 72.4%, and a specificity of 80.6%.
Conclusion
The IDOM is a potentially useful tool for appropriate duration at the outset of OA.
5.Overview of Legal Measures for Managing Workplace COVID-19 Infection Risk in Several Asia-Pacific Countries
Miller DEREK ; Feng-Jen TSAI ; Jiwon KIM ; Mila TEJAMAYA ; Vilandi PUTRI ; Go MUTO ; Alex REGINALD ; Wantanee PHANPRASIT ; Nelia GRANADILLOS ; Marina Bt Zainal FARID ; Carmela Q. CAPULE ; Yu-Wen LIN ; Jihoon PARK ; Ruey-Yu CHEN ; Kyong Hui LEE ; Jeongim PARK ; Haruo HASHIMOTO ; Chungsik YOON ; Chantana PADUNGTOD ; Dong-Uk PARK
Safety and Health at Work 2021;12(4):530-535
Background:
Despite the lack of official COVID-19 statistics, various workplaces and occupations have been at the center of COVID-19 outbreaks. We aimed to compare legal measures and governance established for managing COVID-19 infection risks at workplaces in nine Asia and Pacific countries and to recommend key administrative measures.
Methods:
We collected information on legal measures and governance from both general citizens and workers regarding infection risks such as COVID-19 from industrial hygiene professionals in nine countries (Indonesia, India, Japan, Malaysia, New Zealand, Republic of the Philippines, Republic of Korea, Taiwan, and Thailand) using a structured questionnaire.
Results:
A governmental body overseeing public health and welfare was in charge of containing the spread and occurrence of infectious diseases under an infectious disease control and prevention act or another special act, although the name of the pertinent organizations and legislation vary among countries. Unlike in the case of other traditional hazards, there have been no specific articles or clauses describing the means of mitigating virus risk in the workplace that are legally required of employers, making it difficult to define the responsibilities of the employer. Each country maintains own legal systems regarding access to the duration, administration, and financing of paid sick leave. Many workers may not have access to paid sick leave even if it is legally guaranteed.
Conclusion
Specific legal measures to manage infectious disease risks, such as providing proper personal protective equipment, education, engineering control measures, and paid sick leave are recommended to be stipulated in Industrial safety and health-related acts.
6.The albumin to globulin ratio is associated with clinical outcome in Japanese patients with ulcerative colitis
Sen YAGI ; Shinya FURUKAWA ; Kana SHIRAISHI ; Teruki MIYAKE ; Kazuhiro TANGE ; Yu HASHIMOTO ; Shogo KITAHATA ; Tomoe KAWAMURA ; Tomoyuki NINOMIYA ; Kenichirou MORI ; Seiyuu SUZUKI ; Naozumi SHIBATA ; Hidehiro MURAKAMI ; Katsuhisa OHASHI ; Aki HASEBE ; Hideomi TOMIDA ; Yasunori YAMAMOTO ; Eiji TAKESHITA ; Yoshio IKEDA ; Yoichi HIASA
Annals of Coloproctology 2023;39(2):155-163
Purpose:
The albumin-to-globulin ratio (AGR) is a recognized chronic inflammation marker. No evidence regarding the relationship between AGR level and ulcerative colitis (UC) exists. The aim of this study was to evaluate the association between AGR and clinical outcomes among Japanese subjects with UC.
Methods:
The study subjects consisted of 273 Japanese individuals with UC. AGR was divided into 4 categories (low, moderate, high, and very high). The definition of complete mucosal healing (MH) was based on the Mayo endoscopic subscore of 0. Clinical remission (CR) was defined as no rectal bleeding and no abnormally high stool frequency (<3 times per day).
Results:
The percentage of MH was 26.4%. High AGR and very high AGR were significantly positively correlated with CR (adjusted odds ratio [OR], 5.85; 95% confidence interval [CI], 2.52–14.18 and adjusted OR, 4.97; 95% CI, 2.14–12.04) and complete MH (adjusted OR, 4.03; 95% CI, 1.56–11.51 and adjusted OR, 5.22; 95% CI, 1.97–14.89), respectively after adjustment for confounding factors (P for trend=0.001). Only in the low C-reactive protein (CRP) group (≤0.1 mg/dL), very high AGR was significantly positively correlated with complete MH but not CR (adjusted OR, 4.38; 95% CI, 1.06–21.77; P for trend=0.017). In the high CRP group, no correlation between AGR and complete MH was found.
Conclusion
Among Japanese patients with UC, AGR may be independently positively correlated with complete MH. In particular, among UC patients with low CRP, AGR might be a useful complementary marker for complete MH.