1.Effect of SARS-CoV-2 infection on semen quality in males:a retrospective study and meta-analysis
Yaodong ZHANG ; Yaqing ZHU ; Yue ZHANG ; Youting LI ; Yuanbo HU ; Taofei YAN ; Jufen ZHENG ; Hongli YAN ; Jian XU
Chinese Journal of Clinical Laboratory Science 2024;42(2):141-148
Objective To investigate the impact of SARS-CoV-2 infection on male semen quality through meta-analysis and retrospec-tive study.Methods Literature retrieval was conducted in PubMed,CNKI,Wanfang Database and CBM database.Meta-analysis was performed using Stata 15.0.The male patients meeting the inclusion criteria from our hospital were enrolled as study subjects.General demographic data and semen parameters were collected.Single factor analysis of variance and graphing of semen parameters were con-ducted using GraphPad Prism 9.5.1.The test level was set at 0.05.Results A total of 9 studies involving 267 patients were included in the meta-analysis.There were no significant differences in sperm concentration and survival rate before and after SARS-CoV-2 infec-tion(P>0.05).Semen volume and percentage of normal morphology significantly increased during 1-3 months after infection(P=0.005,P=0.010),with semen volume recovering to pre-infection level>3 months later(P>0.05).Sperm motility and progressive mo-tility increased>3 months after infection(P=0.046,P=0.045),recovering to pre-infection levels(P=0.099,P=0.098).Sperm DNA fragmentation index may be temporarily elevated within 3 months after infection but gradually decreased>3 months later.In the retrospective study of 8 cases,there were no statistical differences in semen parameters at different stages compared with pre-infection(P>0.05),but semen parameters showed a negative trend during<1 month after infection and recovered to pre-infection levels>3 months later.Conclusion The results of this laboratory study are basically consistent with the meta-analysis.SARS-CoV-2 infection in males only caused short-term negative effects on sperm morphology,vitality and DNA integrity,but generally recovered to pre-infection levels>3 months after infection.Due to the limitations of study subjects and sample size,the impact of SARS-CoV-2 infection on male semen quality needs to be further confirmed by long-term large-scale prospective studies.
2.Survey of information needs and its influencing factors in nursing administrators
Ping FANG ; Li YANG ; Qianya MA ; Youting SHI ; Ying ZHU ; Xuemei ZHU ; Ningning XIAO ; Dan CUI
Chinese Journal of Modern Nursing 2014;20(21):2694-2696
Objective To understand the current situation and influencing factor of information needs in nursing administrators , so as to seek the effective methods and ways to meet their needs and improve their information ability .Methods Sixty-eight nursing administrators were surveyed by the self -designed questionnaire about the demographic data , the contents, the ways and barriers of information needs and so on .Results The percent of nursing administrators who often participated in the training of management related knowledge and information retrieval were respectively 23.5% and 1.5%.The information needs in daily work is mainly the business management (38.3%) and professional knowledge and skills (36.8%).The contents of information needs in nursing administrators were mainly the nursing quality management (42.6%), final cost management (23.5%) and management psychology (22.1%).The analysis of the location of searching the information showed that the cases of nurses who searched the information in the library , department , home and internet bar were respectively 58 (85.3%),3 (4.4%),27 (39.7%),2 (2.9%).The main obstacles to search the information were respectively the poor level of computer (3,4.4%), the poor level of English (44,64.7%), the lack of time (32,47.1%) and the lack of retrieval knowledge (28,41.2%).Conclusions The information needs in nursing administrators is mainly the information of increasing the quality of nursing management , and the main factors on affecting the needs were the level of English and the knowledge of literature retrieval .The management departments should strengthen the training of nursing administrators , and the library should play its functions to meet the needs of nursing administrators .