Objective:The aim of the study was to develop a transcultural adaptation of Scrub Practitioners ′ List of Intraoperative Non-technical Skills to Chinese. Methods:The translation of SPLINTS was based on the Brislin ′s translation model and expert consultation were conducted for cultural adaptation before the Chinese version was accomplished. The content validity of Chinese version scale was evaluated by Delphi method. The applicability and observer reliability of the tool was tested by behavioral observation of simulate videos. Results:The positive coefficients of experts in the first and second rounds were both 100% and the authority coefficients were 0.802 and 0.906 respectively. The concordancy coefficients of expert Kendall were 0.282-0.433( P<0.05). The results of Delphi expert consultation showed that the average content validity index (S-CVI/Ave) of the scale level was 0.93, and the item level (I-CVI) content validity index was 0.87-1.00. The rater training showed that the intra-observer reliability was 0.75-0.96 and inter-observer reliability (Kendall W) was 0.502-0.557( P<0.01). Conclusion:The cross-cultural adaptation of SPLINTS-Chinese version is scientific and reliable. The content validation and observer reliability are in-line with scale evaluation criteria. Further psychometric measurement can be conducted in the group of scrub nurses in the operating room.

Objective To construct a motivation goal framework for changes in transcultural self-management health behaviors among senile patients with chronic heart failure (CHF). Methods Totally 15 experts were selected to participate in Delphi consultancy from September 2016 to September 2017. Two rounds of questionnaire consultancy were conducted in terms of the proposed items for the motivation goal framework for changes in transcultural self-management health behaviors among senile CHF patients, with an unanimous understanding among the experts attained. Finally, the motivation goal framework for changes in transcultural self-management health behaviors among senile CHF patients was preliminarily constructed. Results The preliminarily constructed motivation goal framework for changes in transcultural self-management health behaviors among senile CHF patients included 3 primary items, 9 secondary items and 52 tertiary items. The authority coefficient, judgement coefficient and degree of familiarity of these experts were 0.930, 0.950 and 0.910, respectively. The return rate of valid questionnaires in the two rounds of expert consultancy reached 100%. Conclusions The motivation goal framework for changes in transcultural self-management health behaviors among senile CHF patients constructed under the transcultural nursing theory and the cross-theoretical model is scientific and practical, which provides reference for personalized, precise and normalized self-management education.

Objective? To construct and test the reliability and validity of Cultural Competence Scale for Higher Vocational Nursing Students in China. Methods? By means of literature review and Delphi method, Cultural Competence Scale for Higher Vocational Nursing Students was preliminarily formed. In November 2017, by convenient sampling, 300 students majoring in higher vocational nursing in Shanghai were selected for pre-survey. Items were screened through project analysis, and the scale was evaluated by reliability and validity test. In April 2018, 1 479 students from four higher vocational nursing colleges in Shanghai were selected for formal investigation and the structure validity of the scale was further tested by confirmatory factor analysis. Results? Cultural Competence Scale for Higher Vocational Nursing Students included 7 factors and 64 items. Exploratory factor analysis shows that 7 factors of the scale explained 59.692% variance. Confirmative factor analysis shows that the model fitted well. The content validity index of the scale was 0.970, the internal consistency reliability Cronbach's a coefficient was 0.973, Guttman's half-fold reliability coefficient was 0.904 and retest reliability was 0.933. Conclusions? Cultural Competence Scale for Higher Vocational Nursing Students has good reliability and validity, and can be used to measure the cultural competence of nursing students in higher vocational colleges.

The concept and the importance of non-technical skills, relevant influence factors and assessment tools were reviewed. Introduction of non-technical skills measuring tool used at home and abroad from object, content, evaluation method, the result and the application status, then puts forward thinking for the lack of assessment tools. To evaluate the present situation of non-technical skills of the surgical team and members as well as to offer suggestion to improve training effect.

Extended circulation of anticancer nanodrugs in blood stream is essential for their clinical applications. However, administered nanoparticles are rapidly sequestered and cleared by cells of the mononuclear phagocyte system (MPS). In this study, we developed a biomimetic nanosystem that is able to efficiently escape MPS and target tumor tissues. The fabricated nanoparticles (TM-CQ/NPs) were coated with fibroblast cell membrane expressing tumor necrosis factor (TNF)-related apoptosis inducing ligand (TRAIL). Coating with this functionalized membrane reduced the endocytosis of nanoparticles by macrophages, but increased the nanoparticle uptake in tumor cells. Importantly, this membrane coating specifically induced tumor cell apoptosis via the interaction of TRAIL and its cognate death receptors. Meanwhile, the encapsulated chloroquine (CQ) further suppressed the uptake of nanoparticles by macrophages, and synergized with TRAIL to induce tumor cell apoptosis. The vigorous antitumor efficacy in two mice tumor models confirmed our nanosystem was an effective approach to address the MPS challenge for cancer therapy. Together, our TM-CQ/NPs nanosystem provides a feasible approach to precisely target tumor tissues and improve anticancer efficacy.