Purpose: When evaluation and treatment of burn patients were not performed appropriately, patients can get complication and even lead to death. This study was performed to investigate the epidemiological characteristics, prognostic factors of admitted burn patients and thus help establishing therapeutic plan for them. Methods: A retrospective review was performed on all admitted burn patients from January 2013 to December 2022 through emergency center. Age, sex, burn mechanism, burn depth, TBSA, inhalation injury, mechanical ventilation, operation, lab, underlying disease was collected as variables. Length of stay, ICU admission, developing complications, mortality was collected as prognosis. Results: 1,159 patients were enrolled. Baseline characteristics of patients were women 523 (45.1%), age 36.2±24.8 yrs, TBSA 7.0±10.2%, inhalation injury 45 cases (3.8%), mechanical ventilation 50 cases (4.3%), operation 315 cases (30.3%), WBC 10035±4572/uL, CRP 8.1±27.1 mg/L, albumin 4.0±0.5 g/dL, DM 77 cases (6.6%), HTN 175 cases (15.1%), caner 15 cases (1.3%), hospital day 21.2±21.0 days, ICU admission 111 cases (9.6%),complication 36 cases (3.1%), death 21 cases (1.8%). The factors that increase the risk in all four prognosis : hospital days, ICU admission, complications, death were flame burn, full-thickness burn, TBSA over 20%, mechanical ventilation, WBC abnormalities, albumin abnormalities. Conclusion Burn patients who admitted through emergency center are mostly scalding burn, second degree burn, TBSA 0∼5%. Patients with flame burn, full-thickness burn, TBSA over 20%, mechanical ventilation, WBC abnormalities, albumin abnormalities had worse prognosis. Otherwise, patients with scalding burn and second degree burn showed favorable outcomes.

Purpose: Due to coronavirus disease 2019 (COVID-19) outbreak, many epidemiological and clinical factors of burn patients visiting emergency department (ED) have changed. We theorized that this is because of government’s quarantine regulation and fear of COVID-19 infection. Methods: This study investigated all burn patients visited ED from January 2018 to December 2021 without exclusion factors. We defined COVID-19 pandemic period from 2020 to 2021. We analyze many variables of burn patients related to social distancing and change of patients’ lifestyle due to COVID-19 outbreak. Results: The total visit of burn patients from 2018 to 2019 was 1662 and from 2020 to 2021 was 716. There was decrease in rate of admission, follow-up in outpatients and operation. However, there was increase in ratio of burn mechanism and burn causes related to cooking at home such as oil, frying pan and hot pot. Social distancing reduced the rate of burn happened in restaurant and public places but elevated the rate of burn occurred at home. Inhalation related burn rate has increased after COVID-19 outbreak because of increase in time spent indoor than outdoor. Conclusion Since COVID-19 infection and quarantine have brought lots of life pattern alterations, the number of burn patients visiting to the ED has reduced and many epidemiology factors of burn have changed. According to these changes, we concluded that COVID-19 worsen the burn injury due to delay in treatment. These findings could be handful in preparing emergency medicine resources for ongoing and future pandemics.

Sunitinib is a multi-target tyrosine kinase inhibitor used to treat gastrointestinal stromal tumors, renal cell carcinoma, and pancreatic neuroendocrine tumors. The most common adverse reactions are known to be nausea, fatigue, diarrhea, stomatitis, esophagitis, hypertension, skin toxicity (hand-foot syndrome), hypothyroidism, and reduction in the cardiac output of the left ventricle. Herein, we report the case of a 57 year-old female who visited our hospital complaining of epigastric pain. She had been taking sunitinib at 25 mg/day to treat a metastatic pancreatic neuroendocrine tumor. Upon computed tomography performed on admission, we observed that fluid had collected around the pancreas. Laboratory analysis revealed hypertriglyceridemia (triglycerides 993 mg/dL). Tyrosine kinase inhibitors are known to have limited effects on lipid metabolism. In this case, we suggest that hyperglycemia seems to have had a limited effect on lipid levels. We are rather of the view that hyperglycemia, a history of distal pancreatectomy, and hypothyrodisim, indirectly caused the observed hypertriglyceridemia.
Carcinoma, Renal Cell ; Cardiac Output ; Diarrhea ; Esophagitis ; Fatigue ; Female ; Gastrointestinal Stromal Tumors ; Heart Ventricles ; Humans ; Hyperglycemia ; Hypertension ; Hypertriglyceridemia* ; Hypothyroidism ; Lipid Metabolism ; Nausea ; Neuroendocrine Tumors* ; Pancreas ; Pancreatectomy ; Protein-Tyrosine Kinases ; Skin ; Stomatitis