This research was initiated as a preliminary work-up of information system development for primary health care delivery by community health practitioners in rural areas in Korea. The study was focused on the necessary information for enhancing the works of the community health practitioners and that required for health promotion and maintenance within the community. The data were obtained by a questionnaire survey from 458 community health practitioners who participated in computer related education from June 25th to September 26th, 2001. Only 288 (62.9%) of 458 responses were selected for evaluation due to incomplete returns. The majority(76.8%) of participants was using computer once a day at the healthcare centers and the duration of computer usage was more than one year in most cases. The primary usage of computer was for making documents, sending and receiving e-mails, and searching information on the internet. On the contrary, other skills and functions as data management, statistics, web development, games, program development, e-business, and searching for books and articles were not as readily utilized. The essential information for enhancing the performance of the community health practitioners appeared to be that related to drugs and diseases primarily. Other items for respondents in the decreasing order of importance were minimizing manual paper-works, computerized business, computer education, and media development and materials for health education, respectively. The overall information need of respondents was the highest on health and disease, and that on others such as health education, health promotion, elderly care, and fitness exercises were high also. In summary, the community health practitioners should have applicable information system to enhance their performance by obtaining necessary health maintenance and promotion information; by networking available resources; and by enabling them to adapt to rapidly changing policies and work environment. The outcome of this study may provide information elements necessary in development of Health Information Systems for community health practitioners.
Aged ; Commerce ; Surveys and Questionnaires ; Delivery of Health Care ; Education ; Electronic Mail ; Exercise ; Health Education ; Health Information Systems ; Health Promotion ; Humans ; Information Systems ; Internet ; Korea ; Primary Health Care ; Program Development

Objective: This study seeks to evaluate the association between the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the severity of depression and anxiety in the Korean community during the period dominated by the Omicron variant. Methods: We used data from the 2022 Daejeon Mental Health Survey, involving data of 985 participants aged 19–69 years. The data collected included SARS-CoV-2 infection experience, days post-infection, and depression and anxiety symptoms evaluated using the Patient Health Questionnaire-9 and the Generalized Anxiety Disorder Questionnaire-7, respectively. Additionally, physical health, social activity status, and sociodemographic characteristics such as gender, age, marital status, educational level, and household income were collected. The association between SARS-CoV-2 infection and depression and anxiety were examined. Further analyses explored association between days post- infection and the severity of depression and anxiety. Results: There was no significant correlation between SARS-CoV-2 infection and depression and anxiety in the overall population. Notably, participants under 50 years of age exhibited a transient worsening of depression and anxiety, followed by a decrease in symptoms within 40 days. Participants aged 51 years and older showed no significant change in depression and anxiety. Conclusion This study discerned transient effects of Omicron variant infection on depression and anxiety, particularly in younger individuals. A prospective study encompassing a larger sample size is imperative to investigate the influence of SARS-CoV-2 infection on depression and anxiety.

PURPOSE: This study aimed to investigate the potential of freeze-dried persimmon powder (Diospyros kaki Thumb.) to protect against dyslipidemia induced by a high-fat/cholesterol diet (HFD) in a rat model. METHODS: Fifty Wistar rats were randomly divided into five groups: normal control (NC), high-fat/cholesterol control (HC), tannin in HFD (HT, 1% of diet), immature persimmon in HFD (HI, 7% of diet), and mature persimmon in HFD (HM, 7% of diet). Tannin was used as a positive control. Biochemical, molecular, and histopathological changes were observed in the blood and liver. RESULTS: We confirmed that a high fat/cholesterol diet successfully induced dyslipidemia, which was characterized by significantly altered lipid profiles in the plasma and liver. However, oxidized low-density lipoprotein levels, histopathological damage in the liver, and hepatic triglyceride levels were significantly reduced in all HT, HI, and HM groups compared to those in the HF group. In contrast, plasma apolipoprotein B level was significantly reduced only in the HT and HM groups, whereas reduction of the LDL-C level was detected only in the HI group. Although HF-induced sterol regulatory element-binding protein (SREBP) gene expression was significantly reduced in all treated groups, downstream gene expression levels varied among the different groups; significant reduction of fatty acid synthase (FAS) and 3-hydroxy-3-methylglutaryl-CoA (HMGCR) gene expression was detected only in the HI group, whereas cholesterol 7α-hydroxylase (CYP7A1) gene expression was significantly elevated only in the HM group. CONCLUSION: Taken together, the data suggest that protection of LDL oxidation and hepatic lipogenesis might be, at least partly, attributed to tannin in persimmons. However, the identified mechanisms varied up to the maturation stage of persimmon. In the case of immature persimmon, modulation of FAS and HMGCR gene expression was prominent, whereas in the case of mature persimmon, modulation of CYP7A1 gene expression was prominent.
Animals ; Apolipoproteins ; Cholesterol ; Diet ; Diospyros* ; Dyslipidemias ; Gene Expression ; Lipogenesis ; Lipoproteins ; Liver ; Models, Animal ; Plasma ; Rats* ; Rats, Wistar ; Triglycerides