1.Association of ambulatory blood pressure monitoring with renal outcome in patients with chronic kidney disease
Hyung Eun SON ; Ji Young RYU ; Suryeong GO ; Youngjin YI ; Kipyo KIM ; Yoon Kyu OH ; Kook-Hwan OH ; Ho Jun CHIN
Kidney Research and Clinical Practice 2020;39(1):70-80
Background:
The significance of ambulatory blood pressure (ABP) in Korean patients with chronic kidney disease (CKD) in relation to renal outcome or death remains unclear. We investigated the role of ABP in predicting end-stage renal disease or death in patients with CKD.
Methods:
We enrolled 387 patients with hypertension and CKD who underwent ABP monitoring and were followed for 1 year. Data on clinical parameters and outcomes from August 2014 to May 2018 were retrospectively collected. The composite endpoint was end-stage renal disease or death. Patients were grouped according to the mean ABP.
Results:
There were 66 endpoint events, 52 end-stage renal disease cases, and 15 mortalities. Among all patients, one developed end-stage renal disease and died. Mean ABP in the systolic and diastolic phases were risk factors for the development of composite outcome with hazard ratios of 1.03 (95% confidence interval [CI], 1.01-1.04; P < 0.001) and 1.04 (95% CI, 1.02-1.07; P = 0.001) for every 1 mmHg increase in BP, respectively. Patients with mean ABP between 125/75 and 130/80 mmHg had a 2.56-fold higher risk for the development of composite outcome (95% CI, 0.72-9.12; P = 0.147) as compared to those with mean ABP ≤ 125/75 mmHg. Patients with mean ABP ≥ 130/80 mmHg had a 4.79-fold higher risk (95% CI, 1.68-13.70; P = 0.003) compared to those with mean ABP ≤ 125/75 mmHg. Office blood pressure (OBP) was not a risk factor for the composite outcome when adjusted for covariates.
Conclusion
In contrast to OBP, ABP was a significant risk factor for end-stage renal disease or death in CKD patients.
2.Donor body mass index over 30 is no barrier for pure laparoscopic donor right hepatectomy
Suk Kyun HONG ; Minseob KIM ; Youngjin KIM ; Jae-Yoon KIM ; Jaewon LEE ; Jiyoung KIM ; Su Young HONG ; Jeong-Moo LEE ; YoungRok CHOI ; Nam-Joon YI ; Kwang-Woong LEE ; Kyung-Suk SUH
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(3):337-343
Background:
s/Aims: Challenges arise when translating pure laparoscopic donor right hepatectomy (PLDRH) results from Asian to Western donors, due to differences in body mass index (BMI). This study compares the outcomes of PLDRH and conventional open donor right hepatectomy (CDRH) in donors with BMI over 30.
Methods:
Medical records of live liver donors (BMI > 30) undergoing right hepatectomy (2010−2021) were compared: 25 PLDRH cases vs. 19 CDRH cases. Donor and recipient demographics, operative details, and outcomes were analyzed.
Results:
PLDRH and CDRH had similar donor and recipient characteristics. PLDRH had longer liver removal and warm ischemic times, but a shorter post-liver removal duration than CDRH. Donor complication rates were comparable, with the highest complication being grade IIIa in PLDRH, necessitating needle aspiration for biloma on postoperative day 11. Fortunately, this donor fully recovered without additional treatment. No complications exceeding Clavien–Dindo grade IIIa occurred in either group. Recipient outcomes between the groups were similar.
Conclusions
This study supports PLDRH as a viable option for donors with BMI over 30, challenging the notion that high BMI should deter considering PLDRH. The findings provide valuable insights into the safety and feasibility of PLDRH, encouraging further exploration of this technique in diverse donor populations.
3.Donor body mass index over 30 is no barrier for pure laparoscopic donor right hepatectomy
Suk Kyun HONG ; Minseob KIM ; Youngjin KIM ; Jae-Yoon KIM ; Jaewon LEE ; Jiyoung KIM ; Su Young HONG ; Jeong-Moo LEE ; YoungRok CHOI ; Nam-Joon YI ; Kwang-Woong LEE ; Kyung-Suk SUH
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(3):337-343
Background:
s/Aims: Challenges arise when translating pure laparoscopic donor right hepatectomy (PLDRH) results from Asian to Western donors, due to differences in body mass index (BMI). This study compares the outcomes of PLDRH and conventional open donor right hepatectomy (CDRH) in donors with BMI over 30.
Methods:
Medical records of live liver donors (BMI > 30) undergoing right hepatectomy (2010−2021) were compared: 25 PLDRH cases vs. 19 CDRH cases. Donor and recipient demographics, operative details, and outcomes were analyzed.
Results:
PLDRH and CDRH had similar donor and recipient characteristics. PLDRH had longer liver removal and warm ischemic times, but a shorter post-liver removal duration than CDRH. Donor complication rates were comparable, with the highest complication being grade IIIa in PLDRH, necessitating needle aspiration for biloma on postoperative day 11. Fortunately, this donor fully recovered without additional treatment. No complications exceeding Clavien–Dindo grade IIIa occurred in either group. Recipient outcomes between the groups were similar.
Conclusions
This study supports PLDRH as a viable option for donors with BMI over 30, challenging the notion that high BMI should deter considering PLDRH. The findings provide valuable insights into the safety and feasibility of PLDRH, encouraging further exploration of this technique in diverse donor populations.
4.Donor body mass index over 30 is no barrier for pure laparoscopic donor right hepatectomy
Suk Kyun HONG ; Minseob KIM ; Youngjin KIM ; Jae-Yoon KIM ; Jaewon LEE ; Jiyoung KIM ; Su Young HONG ; Jeong-Moo LEE ; YoungRok CHOI ; Nam-Joon YI ; Kwang-Woong LEE ; Kyung-Suk SUH
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(3):337-343
Background:
s/Aims: Challenges arise when translating pure laparoscopic donor right hepatectomy (PLDRH) results from Asian to Western donors, due to differences in body mass index (BMI). This study compares the outcomes of PLDRH and conventional open donor right hepatectomy (CDRH) in donors with BMI over 30.
Methods:
Medical records of live liver donors (BMI > 30) undergoing right hepatectomy (2010−2021) were compared: 25 PLDRH cases vs. 19 CDRH cases. Donor and recipient demographics, operative details, and outcomes were analyzed.
Results:
PLDRH and CDRH had similar donor and recipient characteristics. PLDRH had longer liver removal and warm ischemic times, but a shorter post-liver removal duration than CDRH. Donor complication rates were comparable, with the highest complication being grade IIIa in PLDRH, necessitating needle aspiration for biloma on postoperative day 11. Fortunately, this donor fully recovered without additional treatment. No complications exceeding Clavien–Dindo grade IIIa occurred in either group. Recipient outcomes between the groups were similar.
Conclusions
This study supports PLDRH as a viable option for donors with BMI over 30, challenging the notion that high BMI should deter considering PLDRH. The findings provide valuable insights into the safety and feasibility of PLDRH, encouraging further exploration of this technique in diverse donor populations.
5.Donor body mass index over 30 is no barrier for pure laparoscopic donor right hepatectomy
Suk Kyun HONG ; Minseob KIM ; Youngjin KIM ; Jae-Yoon KIM ; Jaewon LEE ; Jiyoung KIM ; Su Young HONG ; Jeong-Moo LEE ; YoungRok CHOI ; Nam-Joon YI ; Kwang-Woong LEE ; Kyung-Suk SUH
Annals of Hepato-Biliary-Pancreatic Surgery 2024;28(3):337-343
Background:
s/Aims: Challenges arise when translating pure laparoscopic donor right hepatectomy (PLDRH) results from Asian to Western donors, due to differences in body mass index (BMI). This study compares the outcomes of PLDRH and conventional open donor right hepatectomy (CDRH) in donors with BMI over 30.
Methods:
Medical records of live liver donors (BMI > 30) undergoing right hepatectomy (2010−2021) were compared: 25 PLDRH cases vs. 19 CDRH cases. Donor and recipient demographics, operative details, and outcomes were analyzed.
Results:
PLDRH and CDRH had similar donor and recipient characteristics. PLDRH had longer liver removal and warm ischemic times, but a shorter post-liver removal duration than CDRH. Donor complication rates were comparable, with the highest complication being grade IIIa in PLDRH, necessitating needle aspiration for biloma on postoperative day 11. Fortunately, this donor fully recovered without additional treatment. No complications exceeding Clavien–Dindo grade IIIa occurred in either group. Recipient outcomes between the groups were similar.
Conclusions
This study supports PLDRH as a viable option for donors with BMI over 30, challenging the notion that high BMI should deter considering PLDRH. The findings provide valuable insights into the safety and feasibility of PLDRH, encouraging further exploration of this technique in diverse donor populations.