PURPOSE: The aim of this study is to establish anatomical dimension of the nose and nostril shape in Korean twenties. METHODS: Authors measured anthropometry of nose in Korean youths 1,000 individuals(male 363, female 637) and analyzed stastically them. RESULTS: The mean measurements are as follows. 1. The shape of nostrils was classified into 7 types by the angle between both long axis of nostril(male/ female). Type I(<40degrees)1.7%/1.72%, Type II(41-70degrees) 26.17%/29.35%, Type III(71-100degrees) 39.94%/ 38.77%, Type IV(unclassified) 3.85% /5.80%, Type V(101- 130degrees) 20.93%/17.89%, Type VI(131-180degrees) 7.43%/ 5.96%, Type VII(>180degrees) 0%/0.47%. 2. Lengths(male/female). Width of nasal root: 25.29+/-2.25mm/24.72+/-2.40mm, Width of nose: 37.63+/-2.46mm/34.77+/-2.11mm, Width of columella: 7.18+/-0.92mm/6.92+/-0.86mm, Width of alar: 4.99+/-1.00mm/4.74+/-0.91mm, Width of nostril floor: 10.98+/-1.40mm/10.13+/-1.73mm, Protrusion of nasal tip: 17.12+/-1.95mm/16.88+/-1.84mm, Length of alar: 27.10+/-2.21mm/24.66+/-2.18mm, Length of nasal root: 17.37+/-2.51mm/16.08+/-2.90mm, Depth of nasal root: 7.83+/-1.63mm/6.82+/-1.36mm, Length of columella: 8.13+/-1.40mm/7.30+/-1.46mm, Height of nose: 60.50+/-8.90mm/59.14+/-9.22mm, Height of nasal bridge: 52.68+/-7.49mm/50.57+/-7.71mm. 3.Angles. Nasofacial angle: 30.19+/-3.43degrees/29.13+/-6.31degrees, Nasofrontal angle: 134.88+/-7.25degrees/139.94+/-6.33degrees, Nasolabial angle: 95.08+/-8.95degrees/95.80+/-8.93degrees. 4.Nasal index: 72.60+/-9.57%/68.21+/-7.03%, Nasal tip protrusion-nasal height index: 45.64+/-5.21% /47.09+/- 5.21%, Nasal tip protrusion-nasal width index: 32.61+/-6.83% /31.63+/-6.71% CONCLUSION: These data could be useful reference for anthropometry of nose in Korean twenties.
Adolescent ; Anthropometry ; Axis ; Female ; Humans ; Nose

The posaconazole tablet formulation was developed to have improved bioavailability compared to the oral suspension. Here, we compared posaconazole plasma concentration (PPC) with the posaconazole oral suspension versus the tablet in Korean patients undergoing remission induction chemotherapy for hematologic malignancies. PPC was measured at 3, 8, and 15 days of treatment with the oral suspension (174 patients) or the tablet (40 patients). At all time-points, mean PPC was significantly higher with the tablet compared to the oral suspension. Our findings suggest that posaconazole tablets generate an optimal PPC earlier and in more patients than the oral suspension among Korean patients.
Antifungal Agents ; Biological Availability ; Dosage Forms ; Drug Therapy ; Hematologic Neoplasms* ; Humans ; Plasma* ; Remission Induction ; Tablets