In this study we investigated maternal Helicobacter felis (H. felis) infection status to determine the potential of maternal transmission. Pregnant Beagle dogs were infected experimentally with H. felis. Following the experimental design, the stools of the mother and litters were isolated and assessed for transmission of H. felis at parturition day, 1-week old age and 6-week old age respectively. Polymerase chain reaction (PCR) was used to examine the presence of transmitted H. felis. All litters showed no transmission of H. felis at parturition day. However, they revealed 14.3% and 100% at 1-week old age and 6-week old age respectively by PCR. These results suggested that vertical infection during prenatal period or delivery procedure is unlikely as a route of mother-to-child H. felis infection. It might be acquired H. felis through breast-feeding, contaminating saliva and fecal-oral during co-habitat.
Animals ; Cats ; Dogs ; Felis ; Helicobacter ; Helicobacter felis ; Humans ; Mothers ; Parturition ; Polymerase Chain Reaction ; Postpartum Period ; Research Design ; Saliva

In this study we investigated maternal Helicobacter felis (H. felis) infection status to determine the potential of maternal transmission. Pregnant Beagle dogs were infected experimentally with H. felis. Following the experimental design, the stools of the mother and litters were isolated and assessed for transmission of H. felis at parturition day, 1-week old age and 6-week old age respectively. Polymerase chain reaction (PCR) was used to examine the presence of transmitted H. felis. All litters showed no transmission of H. felis at parturition day. However, they revealed 14.3% and 100% at 1-week old age and 6-week old age respectively by PCR. These results suggested that vertical infection during prenatal period or delivery procedure is unlikely as a route of mother-to-child H. felis infection. It might be acquired H. felis through breast-feeding, contaminating saliva and fecal-oral during co-habitat.
Animals ; Cats ; Dogs ; Felis ; Helicobacter ; Helicobacter felis ; Humans ; Mothers ; Parturition ; Polymerase Chain Reaction ; Postpartum Period ; Research Design ; Saliva

Objective: Gambling disorder (GD) patients have a higher suicide risk compared to the general population. The present study investigates the suicide-related risk factors of GD patients by analyzing GD diagnosis-related symptoms and suicide-related behaviors of subjects. Methods: This study investigated which symptoms among GD diagnosis criteria are related to suicide risk in 142 patients diagnosed with GD. To analyze the relationship between GD symptoms and suicidal ideation and suicide attempt, the odds ratio (OR) was determined through multivariate logistic regression. Results: The number of symptoms was significantly higher in the subjects who had suicidal ideation group and attempt group. In the cases of past suicide attempts, responses to withdrawal and escape questions were significantly higher; in the cases of ongoing suicidal ideation, responses to negative consequences and bailout questions were significantly higher. When depression was corrected, the ‘bailout’ item was, indicating that ‘bailout’ increased suicidal ideation (OR=4.937, 95% CI=1.009–24.164). In the suicide attempt group, ‘relieve’ item may increase suicide attempt (OR=6.978, 95% CI=1.300–35.562). Conclusion Past suicide attempts in GD patients correlated with withdrawal symptoms, and financial problem correlated with suicidal ideation. This suggests that evaluating suicide risk is important when evaluating GD patients, and evaluation of financial problems is important for GD patients with suicide risks.

Background: This study aimed to demonstrate the importance to recognize subjective body image on their mental health on adolescents. Methods: We used the chi-square test and the multiple logistic regression model to analyze the data of the “Korean Youth Health Behavior Survey in 2018” (n=42,259) conducted by the Korea Centers for Disease Control and Prevention. Results: As a result of the analysis, suicide ideation increased when the subject body image is thin and fat. Especially, the suicide ideation who recognized the subjective body image as thin is higher (odds ratio [OR], 1.666; 95% confidence interval [CI], 1.050– 1.295), and who recognized the subjective body image as fat is higher (OR, 1.134; 95% CI, 1.032–1.245) than the group who recognized the subjective body image as normal. Conclusion When preparing a health policy on adolescent suicide issues, we need to consider the association between subjective body image and suicide ideation.

OBJECTIVES: Cardiovascular predictions are related to patients' quality of life and health. Therefore, a risk prediction model for cardiovascular conditions is needed. METHODS: In this paper, we propose a cardiovascular disease prediction model using the sixth Korea National Health and Nutrition Examination Survey (KNHANES-VI) 2013 dataset to analyze cardiovascular-related health data. First, statistical analysis was performed to find variables related to cardiovascular disease using health data related to cardiovascular disease. Second, a model of cardiovascular risk prediction by learning based on the deep belief network (DBN) was developed. RESULTS: The proposed statistical DBN-based prediction model showed accuracy and an ROC curve of 83.9% and 0.790, respectively. Thus, the proposed statistical DBN performed better than other prediction algorithms. CONCLUSIONS: The DBN proposed in this study appears to be effective in predicting cardiovascular risk and, in particular, is expected to be applicable to the prediction of cardiovascular disease in Koreans.
Cardiovascular Diseases ; Dataset ; Korea ; Learning ; Machine Learning ; Nutrition Surveys ; Quality of Life ; ROC Curve

OBJECTIVES: The importance of the prediction of coronary heart disease (CHD) has been recognized in Korea; however, few studies have been conducted in this area. Therefore, it is necessary to develop a method for the prediction and classification of CHD in Koreans. METHODS: A model for CHD prediction must be designed according to rule-based guidelines. In this study, a fuzzy logic and decision tree (classification and regression tree [CART])-driven CHD prediction model was developed for Koreans. Datasets derived from the Korean National Health and Nutrition Examination Survey VI (KNHANES-VI) were utilized to generate the proposed model. RESULTS: The rules were generated using a decision tree technique, and fuzzy logic was applied to overcome problems associated with uncertainty in CHD prediction. CONCLUSIONS: The accuracy and receiver operating characteristic (ROC) curve values of the propose systems were 69.51% and 0.594, proving that the proposed methods were more efficient than other models.
Classification ; Coronary Disease* ; Data Mining ; Dataset ; Decision Trees* ; Fuzzy Logic* ; Heart Diseases ; Korea ; Nutrition Surveys ; ROC Curve ; Uncertainty

OBJECTIVES: Acquiring temporal information is important because knowledge in clinical narratives is time-sensitive. In this paper, we describe an approach that can be used to extract the temporal information found in Korean clinical narrative texts. METHODS: We developed a two-stage system, which employs an exhaustive text analysis phase and a temporal expression recognition phase. Since our target document may include tokens that are made up of both Korean and English text joined together, the minimal semantic units are analyzed and then separated from the concatenated phrases and linguistic derivations within a token using a corpus-based approach to decompose complex tokens. A finite state machine is then used on the minimal semantic units in order to find phrases that possess time-related information. RESULTS: In the experiment, the temporal expressions within Korean clinical narratives were extracted using our system. The system performance was evaluated through the use of 100 discharge summaries from Seoul National University Hospital containing a total of 805 temporal expressions. Our system scored a phrase-level precision and recall of 0.895 and 0.919, respectively. CONCLUSIONS: Finding information in Korean clinical narrative is challenging task, since the text is written in both Korean and English and frequently omits syntactic elements and word spacing, which makes it extremely noisy. This study presents an effective method that can be used to aquire the temporal information found in Korean clinical documents.
Automatic Data Processing ; Linguistics ; Medical Informatics ; Medical Records ; Multilingualism ; Pattern Recognition, Automated ; Semantics

No abstract available.
Aortic Valve Insufficiency*

BACKGROUND: Displaced anterior column fractures have increasingly been treated surgically by the ilioinguinal approach and fixation with lag screws and a buttress plate on the pelvic brim. However, a major disadvantage of the ilioinguinal approach is possible damage to the neurovascular bundle and the lymphatic structures in the intermediate part of the approach. This study aims to present a novel surgical technique of the less invasive anterior iliac approach and compression osteosynthesis for high anterior column fractures of the acetabulum. METHODS: In this retrospective case series, 19 patients treated operatively for isolated high anterior column fractures using the less invasive anterior iliac approach and compression osteosynthesis were included. Patient demographics, the cause of injury, associated injuries, time to surgical reconstruction, and operation time were collected from the medical records. The quality of reduction was assessed by postoperative standard radiographic views and computed tomography scans and graded according to Matta's criteria. Clinical and radiographic grades were assessed according to Matta's criteria at the last follow-up. RESULTS: This less invasive surgical technique was successful for reduction and fixation in all high anterior column fractures and provided sufficient stability to allow immediate mobilization of the patients after surgery. Twelve fractures were combined with the quadrilateral plate fracture and seven fractures did not involve the quadrilateral plate. According to Matta's criteria, anatomical reduction was obtained in 17 patients and imperfect reduction in two patients. Clinical results were excellent in 17 patients and good in two patients. Radiographic results were excellent in 17 patients and good in two patients. Ten patients had neurapraxia of the lateral femoral cutaneous nerve related to the approach, which was resolved completely in seven. One patient had deep vein thrombosis. CONCLUSIONS: Our less invasive surgical technique of the anterior iliac approach and compression osteosynthesis is a useful addition to the existing techniques in the treatment of high anterior column fractures of the acetabulum. Despite being a limited approach and fixation, this technique provides sufficient exposure for reducing and fixing the fracture and adequate stability to allow immediate mobilization of the patient after surgery.
Acetabulum* ; Demography ; Follow-Up Studies ; Humans ; Medical Records ; Retrospective Studies ; Venous Thrombosis

Background: The purpose of this study was to investigate the femoral, acetabular, and combined anteversion of the hip joint in South Koreans using computed tomography (CT). Methods: We measured anteversion using CT venograms taken from 2016 to 2020. Of the total 1,073 patients, 952 patients were included in the study except for those with pelvic fractures, previous femoral fractures, childhood hip joint disease, osteoarthritis, or hip dysplasia (lateral center-edge angle, < 20), foreigners, and hip and knee replacement patients. Measurements were taken twice by two orthopedic surgeons. Results: The femoral anteversion in women was 10.64° ± 10.26° (≤ 49 years), 15.75° ± 9.40° (50–59 years), 10.81° ± 9.14° (60–69 years), 12.38° ± 8.55° (70–79 years), and 11.23° ± 8.44° (≥ 80 years). The femoral anteversion in men was 12.02° ± 11.38° (≤ 49 years), 10.62° ± 9.11° (50–59 years), 6.09° ± 9.95° (60–69 years), 6.57° ± 9.51° (70–79 years), and 5.53° ± 9.29° (≥ 80 years). The acetabular anteversion in women was 17.65° ± 6.58° (≤ 49 years), 19.24° ± 6.42° (50–59 years), 20.30° ± 6.25° (60–69 years), 22.38° ± 7.36° (70–79 years), and 23.34° ± 6.98° (≥ 80 years). The acetabular anteversion in men was 15.21° ± 8.14° (≤ 49 years), 17.68° ± 6.00° (50–59 years), 17.54° ± 5.93° (60–69 years), 18.68° ± 6.62° (70–79 years), and 18.19° ± 6.94° (≥ 80 years). The combined anteversion in women was 28.29° ± 14.30° (≤ 49 years), 34.99° ± 10.62° (50–59 years), 31.11° ± 11.52° (60–69 years), 34.76° ± 10.86° (70–79 years), and 34.57° ± 11.45° (≥ 80 years). The combined anteversion in men was 27.23° ± 15.11° (≤ 49 years), 28.30° ± 11.23° (50–59 years), 23.63° ± 11.77° (60–69 years), 25.25° ± 12.02° (70–79 years), and 23.72° ± 11.88° (≥ 80 years). Conclusions Femoral anteversion tended to decrease with age in men and acetabular anteversion tended to increase in both men and women. Combined anteversion showed a tendency to increase slightly in women.