The patient was a sixty-year-old obese woman with the long history of hypertension, amenorrhea and occasional psychic disturbances. She had eigbt, thumb to adult-fist sized, slightly movable, relatively soft, and painful subcutaneous nodules with tenderness and paresthcsia, of which overlying skin appeared to be normal except senile changes, on the abdomen and both upper extremities for 10 years. There was no evidence of inheritance in her family. Laboratory data revealed no abnormalities in lipid metabolism or in a variety of endocrinological functions. Microscopically, an excised mass from the forearm showed thin connective tissue capsule encircling numerous lobules cornposed entirely of the mature fat. cells vith minimal focal capillary proliferatios.
Abdomen ; Adiposis Dolorosa* ; Amenorrhea ; Capillaries ; Connective Tissue ; Female ; Forearm ; Humans ; Hypertension ; Lipid Metabolism ; Skin ; Thumb ; Upper Extremity ; Wills

Gout is not very rare disorder in high economic countries and it is seldom observed in our country and is hard to find its report in Korean dermatologic literature. Gout is a disease of inbom metabolic and/or acquired form of the disease chara-cterized by hyperuricemia, tophaceous deposits of sodium urate and recurrent attacks of arthrit.is which dramatically responds to Colchine. A case of tophaceous gout in a 56 year old Korean male is reported. The patient showed pea to waInut size, yellowish tender subcutaneous masses on right great toe and both solee of 15 year duration which are adherented to the overIying skin. The hiatology of the lesion revealed variously sized, sharply demarcated aggregates of needle shaped urate crystals in bund.his and sheaves which are surrounded by fibrous connective tissue which are in tum surrounded by granulomatous infiltrate containing small round cells and foreign body glant cells. The urate crystals have a brownish color and are doubly refractile on polariscopic examination. The use of colchine, in a initial dose of 1mg foIIowed by 0. 5mg every hour for 6 hours. The patient failed to attend the clinic regularly and was lost for folIow up.
Connective Tissue ; Foreign Bodies ; Gout* ; Humans ; Hyperuricemia ; Male ; Middle Aged ; Needles ; Peas ; Skin ; Toes ; Uric Acid

The effect of retinoic acid. on hyperkeratotic diseases and. Acne as being published. To confirm the effect of topical retinoic acid, vre subjected 50 patients with mild to severe Acne vulgaris of the face, The patients chosen were not previously treated. with any remedy at least for the past 2 weeks. Eudyna' cream or gel were applied. once or twice a day to the face keeping some distance from the mucous membrane. We checked the number of closed comedones, open comedones, papules, pustules and scara before the treatment and every week for 14 wks during the treatment, The result were as follows: l. 42 patients began to improve in 2 to 8 wks and markedly improved in 6 to 8 wks. 3 patients dropped out because of severe side effects. Very good: 13 patients(26%) Good: 14 patinets(28%) Satisfactory: 15 patients(80%) None: 5 patients(10%) 2. The side effects: Most of patients suffered from mild to severe erythema, scaling and buming sensation in 2 to 3 days after the initiation of application. In severe cases developed severe erythema, vesicles, pustules, edema and exudation within a week.
Acne Vulgaris* ; Edema ; Erythema ; Humans ; Mucous Membrane ; Sensation ; Tretinoin

A cutaneous angiitis showing evidence of leukocytoclastic angiitis in a 17 year old girl is presented. The patient showed multiple pinhead to pea sized erythematoue papular lesions on both legs, right axillary region, left upper chest, palms and especially around the ankles, The lesions did not fade on diascopy and caused mild pruritus and were slightly tender. The lesions had been present for about six months. The definition, classification, pathogenesis and therapeutic aspects of cutan- eous angiitis are reviewd.
Adolescent ; Ankle ; Classification ; Female ; Humans ; Leg ; Peas ; Pruritus ; Thorax ; Vasculitis*

No abstract available.
Adipose Tissue* ; Transplants*

No abstract available.
Adipose Tissue* ; Transplants*

No abstract available.

Adipose Tissue ; Arteries ; Congenital Abnormalities ; Fistula ; Follow-Up Studies ; Humans ; Masseter Muscle ; Necrosis ; Oroantral Fistula ; Tongue

The significance of measurement of the spinal canal size was well recognized in case of detection of intraspinal tumor as well as diagnosis of spinal stenosis. The measurement of sagittal diameter of the lumber spinal canal by plain x-ray film is not always easy. However, the new method designed by Eisenstein made the measurement of sagittal diameter of the lumber spinal canal by plain x-ray film very easy. In order to study the range of normal values of the sagittal diameter of lumber spinal canal in Korean adults, authors measured antero-posterior and transverse diameter of the lumbar spinal canal in 290 normal Korean adults by Eisensteins method. The results obtained are as follows: 1. Mean values of sagittal diameter of the normal Korean adults male was 17.37±1.05mm at Ll, 16.43±1.12mm at L2, 15.89±1.20mm at L3, 15.45±1.24mm at L4, and 17.34±1.13mm at L5 vertebra and in female, 17.41±1.23mm at Ll, 16.45±1.20mm at L2, 16.14±1.41mm at L3, 15.40±1.32mm at L4, and 17.25±1.20mm at L5 vertebra. 2. Mean values of transverse diameter of the normal Korean adults male was 23.54±1.18mm at Ll, 24.61±1.17mm at L2, 25.78±1.41mm at L3, 27.72±1.86mm at L4, and 30.42±2.23mm at L5 vertebra and in female, 23.06±1.45mm at Ll, 23.90±1.48mm at L2, 25.21±1.53mm at L3, 26.62±1.88mm at L4, and 29.70±2.41mm at L5 vertebra. 3. In transverse diameter, it was increased more and more to the lower lumber level, the widest at L5 vertebra. 4. In sagittal diameter, it was decreased less and less to the lower lumbar level, the narrowest at L4, and increased again at L5 vertebra. 5. The difference of sagittal and transverse diameter of lumbar spinal canal at each level of lumbar spine was very significant statistically. 6. The difference of the transverse diameter of the lumber spinal canal between male and female was significant statistically but that of the sagittal diameter was not. 7. The difference of the sagittal and transverse diameter between each age group was not significant statistically.
Adult ; Diagnosis ; Female ; Humans ; Male ; Methods ; Reference Values ; Spinal Canal ; Spinal Stenosis ; Spine ; X-Ray Film

PURPOSE: To evaluate criteria for differentiating benign versus malignant solitary pulmonary nodules (SPNs) by analyzing their morphology and perinodular parenchymal changes on CT/HRCT. MATERIALS AND METHODS: We retrospectively reviewed the CT/HRCT in 99 patients with SPN. Sixty two cases were proved by surgery, PCNA, clinical follow up and etc. Thirty seven cases were diagnosed by typical benign calcification. We defined SPN as a discrete, single lesion in the lung with margins that are sharp enough to permit measurement of diameter. We excluded lesions more than 4cm in diameter and lesions with cavity from our study protocol. The study included 41 malignant nodules and 58 benign nodules. RESULTS: Mean diameter of malignant nodule was 2.9cm, benign nodule was 2.2cm. Peripheral location of nodule was 28 in malignant nodules, 50 in benign nodules. Typical benign calcification was observed in 37 tuberculoma and three hamartoma. Lobulated margin was noted in 32 malignant nodules and 14 benign nodules. Spiculated margin was observed in 17 malignant nodules and 20 benign nodules. Low attenuation within the nodule was observed in 14 malignant nodules and 12 benign nodules. Pleural tail was observed in 14 malignant nodules and 31 benign nodules. Air bronchogram was noted in 18 malignant nodules and 4 benign nodules. Juxta nodular tuberculosis was observed in 6 malignant nodules and 29 benign nodules. CONCLUSION: Malignant nodules were larger than benign nodules and more commonly demonstrated a Iobulated contour and air bronchogram (p<0.05). Benign nodules more commonly demonstrated low density in the nodule and associated with juxta nodular tuberculosis and peripheral location (p<0.05). Spiculated margin and pleural tail were not helpful to differentiate benign from malignant nodule.
Follow-Up Studies ; Hamartoma ; Humans ; Lung ; Proliferating Cell Nuclear Antigen ; Retrospective Studies ; Solitary Pulmonary Nodule* ; Tuberculoma ; Tuberculosis