Gas producing infection accompanied by evidence of subcutaneous gas usually are diagnosed as clostridial gas gangrene. The occurrence of nonclostridial gas producing infection is thought to be relatively rare. Two cases of nonclostridial gas producing infection simulating clostridial gas gangrene in diabetes occurred. Gram stains of pus at the time of admission can isolate the E-coli and streptococcus, and can distinguish these two entities. Chief conplaints were swelling, pain and tenderness of right lower extremity by infection. Multiple incisions to free the tissues of gas and pus and the administration of antibiotics are the treatment of choice.
Anti-Bacterial Agents ; Coloring Agents ; Gas Gangrene ; Lower Extremity ; Streptococcus ; Suppuration

No abstract available in English.

One family with asymmetric septal hypertrophy was reported. The propositus of this family was 31 years old man who was admitted because of transient syncope. His father and one brother were affected but asymptomatic. His sister was suddenly died at age 21 years. The interventricular septal thickness to left ventricular posterior wall thickness ratios were measured using M-mode echocard ogram. In the affected family, echocardiogram revealed asymmetric septal hypertrophy (1.5:1, 2:1, 1.9:1 respectively). In the propositus, cardiac catheterization and simultaneous biventricular cineangiography were performed. Pressure study revealed mild peak systolic pressure gradient within left ventricular apex and left ventricular outflow tract (4mm Hg respectively). Biventricular cineangiogram showed the septal width increased inferiorly, and left ventricular endocardial surface of the septum was straight, while the right ventricular border convex toward the right ventricle.
Adult ; Blood Pressure ; Cardiac Catheterization ; Cardiac Catheters ; Cardiomyopathy, Hypertrophic* ; Cineangiography ; Fathers ; Heart Ventricles ; Humans ; Siblings ; Syncope

PURPOSE: The objective of this study was to identify the relationships among symptom bother, physical and mental stress and health-related quality of life (HRQoL) in women with overactive bladder (OAB) syndrome. METHODS: The participants were 106 women who were diagnosed with OAB (urgency, urge urinary incontinence, frequency, and/or nocturia) at P university hospital. Data were collected from Dec 23, 2011 to Aug 31, 2012. RESULTS: The mean score for symptom bother was 43.1 points, for physical stress, 12.8 which was slightly higher than mental stress (11.8), and for HRQoL, 63.9. For symptom type, there were statistically significant differences in the symptom bother (F=8.67, p<.001) and HRQL (F=3.32, p= .023). The Symptom bother of OAB was positively correlated with physical stress (r=.23, p= .014) and mental stress (r=.33, p<.001) and negatively correlated with the subscales of HRQoL; coping (r=-.66, p<.001), concern (r=-.71, p<.001), sleep (r=-.59, p<.001), and social interaction (r=-.58, p<.001). CONCLUSION: From the results, bother symptom was associated with physical, mental stress and HRQoL. These results suggest that nursing intervention programs for OAB should be developed not only to relieve the symptoms but also to reduce stress and improve the quality of life.
Female ; Humans ; Interpersonal Relations ; Nursing ; Quality of Life* ; Symptom Assessment ; Urinary Bladder, Overactive* ; Urinary Incontinence

The term Down's syndrome is preferred to mongolism. The most constant characteristic of disease is mental retardation. The incidence of Down's syndrome is about 1/600 in the general population, being roughly the same in various parts of world and in all races. The patient's mother's age at the same time of conception as well as the nature of chromosomalmalformation are in genetic counseling. We reported a case of Down's syndrome in 5 year old female who was bone in 38 year old mother, and she was noted epicanthus, nystagmus, esotropia, Brush-field spots. Other systemic manifestation-, Simian crease, short extrimites, inward curved 5th finger, Sandal gap foot, congenital heart disease, prominent abdomen-, was also noted.
Adult ; Child, Preschool ; Continental Population Groups ; Down Syndrome* ; Esotropia ; Female ; Fertilization ; Fingers ; Foot ; Genetic Counseling ; Heart Defects, Congenital ; Humans ; Incidence ; Intellectual Disability ; Mothers

PURPOSE: This study was aimed at evaluating the expressions of types I and III collagen, inducible nitric oxide synthase (iNOS), hypoxic inducible factor-1alpha(HIF-1alpha), vascular endothelial growth factor (VEGF) and the hemodynamic changes of the bladder during the acute stages of a partial bladder outlet obstruction (PBOO) in adult rats. MATERIALS AND METHODS: Bladder specimens were aseptically removed from 35 Sprague-Dawley adult rats (8 week old, weight 250-300gm) of both sham and experimental groups at 6, 12 and 24 hours, and 2, 3, 5 and 7 days after establishing a partial bladder outlet obstruction. Bladder blood flow was measured at the left vesicular artery using a laser flowmeter. The expressions of types I and III collagen, iNOS, HIF-1alpha and VEGF in relation to changes of the bladder wall were evaluated by immunohistochemical staining and Western blot assay. RESULTS: There was a significant difference in the vesical blood flow between the sham and experimental groups after the establishment of a PBOO. The bladder blood flow of the experimental groups was significantly decreased after establishing a PBOO of 3 days duration. The expressions of type III collagen and iNOS from the immunohistochemical staining of the bladder were markedly increased during the acute stages of a PBOO. The expressions of HIF-1alpha and VEGF from the Western blot of the bladder increased with duration of the obstruction. CONCLUSIONS: A decreased bladder blood flow during the acute stages of PBOO generally enhanced the expressions of iNOS and type III collagen. This study suggests that hypoxia of the bladder after establishing a PBOO induces the expression of HIF-1alpha, and then enhances the production of nitric oxide (NO) due to activation of iNOS, which finally results in bladder growth and a decrease in bladder wall compliance.
Adult ; Animals ; Anoxia ; Arteries ; Blotting, Western ; Collagen ; Collagen Type III ; Compliance ; Flowmeters ; Hemodynamics ; Humans ; Nitric Oxide ; Nitric Oxide Synthase ; Nitric Oxide Synthase Type II ; Rats* ; Rats, Sprague-Dawley ; Urinary Bladder Neck Obstruction ; Urinary Bladder* ; Vascular Endothelial Growth Factor A

No abstract available.
Spondylitis*

No abstract available.
Angiotensin I ; Angiotensin II* ; Angiotensins* ; Autoradiography ; Receptors, Angiotensin* ; Renin* ; Renin-Angiotensin System*

No abstract available.
Angiotensin I ; Angiotensin II* ; Angiotensins* ; Autoradiography ; Receptors, Angiotensin* ; Renin* ; Renin-Angiotensin System*

There have been few cases of Neurofibromatosis associated with Chronic Myelocytic Leukemia in literature and we found only one report in Korea which described the association of Chronic Myelocytic Leukemia with Neurofibromatosis. We report a case of patient whose clinical and hematological findings were compatible with Chronic Myelocytic Leukemia and Neurofibromatosis. Busulfan was used in the treatment of this patient followed by some degree of remission. A brief review of literature supporting our diagnosis was included in this report.
Busulfan ; Diagnosis ; Humans ; Korea ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive* ; Neurofibromatoses*