1.The Effect of Decreased Serum Glucose on Collagen Contents of Penile Tunica Albuginea and Endothelial Change of Corpus Cavernosum in Long Evans Rat.
Hyun Pyo HONG ; Dae Yul YANG ; Ha young KIM
Korean Journal of Urology 2001;42(6):650-656
PURPOSE: It is reported that 65% of diabetic male patients over 60 of their age are impotent. However, there is no report concerning the effect of serum glucose control on erectile dysfunction in diabetic patient. This study was performed to evaluate the effects of serum glucose control on erectile dysfunction. MATERIALS AMD METHODS: The development of Diabetes mellitus was defined that the serum glucose level was above 200mg/dL in random test at 25 weeks. We designed the experimental specimen into 3 groups; group I: diabetic OLETF (Otsuka Long Evans Tokushima Fatty) rats without blood sugar control (n=10), group II: diabetic OLETF rats with blood sugar control with 4U insulin subcutaneous injection daily from 26 to 46 weeks (n=10), group III: diabetic OLETF rats with blood sugar control with 10U insulin subcutaneous injection daily from 26 to 46 weeks (n=10). We estimated the collagen content of penile tunica albuginea with the scanning electron microscopy and observed the endothelial layers of corpus cavernosum with the transmission electron microscopy in each group. RESULTS: The serum glucose level was 249 +/- 4.1mg/dL, 234 +/- 2.7mg/dL, 215 +/- 3.0mg/dL respectively in group I, II, III, and decreased in order of group II, III. The differences among groups were statistically significant (p<0.05). The thickness of collagen bundles of penile tunica albuginea was 0.98 +/- 0.1 micrometer, 0.94 +/- 0.3 micrometer, 0.92 +/- 0.1 micrometer respectively in group I, II, III, and decreased in order of group II, III. The differences among groups were statistically significant (p<0.05). The endothelial layers of corpus cavernosum were decreased in II, III. CONCLUSIONS: The serum glucose control in diabetic rats decreases the collagen con tents in penile tunica albuginea and the endothelial layers of corpus cavernosum.
Animals
;
Blood Glucose*
;
Collagen*
;
Diabetes Mellitus
;
Endothelium
;
Erectile Dysfunction
;
Humans
;
Injections, Subcutaneous
;
Insulin
;
Male
;
Microscopy, Electron, Scanning
;
Microscopy, Electron, Transmission
;
Rats*
;
Rats, Inbred OLETF
2.Role of Heat Shock Protein, P70 in Spermatogenic Arrest.
Hyun Joo KIM ; Won Young SON ; Tae Young AHN ; Tae Ki YOON ; Kwang Yul CHA
Korean Journal of Urology 2000;41(1):129-137
No abstract available.
Heat-Shock Proteins*
;
Hot Temperature*
3.Role of Heat Shock Protein, P70 in Spermatogenic Arrest.
Hyun Joo KIM ; Won Young SON ; Tae Young AHN ; Tae Ki YOON ; Kwang Yul CHA
Korean Journal of Urology 2000;41(1):129-137
No abstract available.
Heat-Shock Proteins*
;
Hot Temperature*
4.Surgical factors influencing graft survival of 200 renal transplantations.
Korean Journal of Urology 1991;32(5):795-800
Many factors are thought to be affecting to the graft and patient survival. We have analyzed our surgical 200 renal transplantation performed at Kosin Medical Center. Pusan, Korea from December l984 to May 1990. Overall 1 and 3 years graft and patient survival rates were 91.9%, 94.2% 83.6%. and 93.0% respectively. Arterial spasm was occurred in four cases but the difference of occurrence or acute tubular necrosis and graft survival rate were not significant statistically. End to side arterial anastomosis was performed in four cases. Polar artery was ligated in four cases. Average total ischemic time was 50.7 minutes There was no loss of graft loss due to urological complications. We found that there was no notable significance of these selected surgical factors which influencing patient and graft survival at our Medical Center.
Arteries
;
Busan
;
Graft Survival*
;
Humans
;
Kidney Transplantation*
;
Korea
;
Necrosis
;
Spasm
;
Survival Rate
;
Transplants*
5.Breast tumors associated with nipple discharge: US findings with galactographic correlation.
Soo Young CHUNG ; Suk Hyun KIM ; Yul LEE ; Ki Soon PARK
Journal of the Korean Radiological Society 1992;28(6):994-1000
To compare the specific information of each imaging modality of US (7.5MHz, water path system) and galactography, and to appreciate clinical applicability of US as a primary diagnostic method in breast tumor causing nipple discharge, we performed a comparative study of each method in 15 cases of the ductal tumor of breast. To evaluate the demonstrable smallest anatomic unit of the lactiferous system by US, 30 normal lactating breasts were examined prospectively. The visible smallest lactating unit in the normal lactating breast by US is terminal duct lobular unit(TDLU). US is superior to galactography for detection of the mass less than 0.5cm in size with proximal ductal dilatation, and for evaluation of the multiple ductal lesions, in contrast, inferior to galactography for systemic visualization of involving ducts and for the detection of microcalcification. Sonographic diagnosis is limited in detection of small retromammillary masses, peripheral small masses without ductal dilatation and masses in excessively fatty breast. In conclusion US can be a primary diagnostic tool in suspicious breast tumor causing nipple discharge as a non-invasive method but galactography should be combined in the indicated cases.
Breast Neoplasms*
;
Breast*
;
Diagnosis
;
Dilatation
;
Methods
;
Nipples*
;
Prospective Studies
;
Ultrasonography
;
Water
6.Transient common bile duct dilatation in infants.
Jee Young KIM ; Ok Hwa KIM ; Hyun Sook KIM ; Choon Yul KIM ; Yong Whee BAHK
Journal of the Korean Radiological Society 1992;28(2):293-296
Follow-up sonographic studies of three infants, whose initial sonograms showed findings suggestive of choledochal cyst, demonstrated disappearance of cystic dilatation of the common bile ducts. The phenomena could be accounted for by acute common bile duct obstruction secondary to bile sludge. Bile plug syndrome should also be included in the differencial diagnosis. When a cystic or fusiform dilatation of the common bile duct is seen on sonogram. Conservative management must be the choice of approach unless the finding is proven to unchanged over a period of time and irreversible.
Bile
;
Choledochal Cyst
;
Common Bile Duct*
;
Diagnosis
;
Dilatation*
;
Follow-Up Studies
;
Humans
;
Infant*
;
Sewage
;
Ultrasonography
7.A clinical analysis of fistula-in-ano.
Sang Yul CHO ; Tae Young JUNG ; Chang Woo LEE ; Sang Hyun KIM
Journal of the Korean Surgical Society 1991;41(4):520-524
No abstract available.
8.A study on influence of korea medical insurance and health care delivery system to family practice inpatient care.
Dong Yoon KO ; Hyun Dong YOO ; Young Gyu PARK ; Jung Yul OH ; Myung Ho HONG
Journal of the Korean Academy of Family Medicine 1993;14(4):265-270
No abstract available.
Delivery of Health Care*
;
Family Practice*
;
Humans
;
Inpatients*
;
Insurance*
;
Korea*
9.Evaluation of family function in the inpatient of rehabilitation medicine department witn impairment of activity of daily living.
Eung Su KIM ; Jang Kyun OH ; Sang Young LEE ; Sun Yul KIM ; Hyun Jin KIM
Journal of the Korean Academy of Family Medicine 1997;18(3):336-350
BACKGROUND: When one of family members must be treated, the others are required to get various forms of changes including modification of their proper roles in the family. Particularily when he or she can not perform his or her activities of daily living(ADL) owing to functional impairment by himself or herself, there seems to be greater dependence upon his or her family. Accordingly, we tried to give help in the treatment of patients through the comparative analysis concerning functional impairment in both groups on the assumption that there is difference of family function between two family groups which have a patient in family, or not. METHODS: This study was carried out to 83 inpatients in Sun Hospital in Dae Jeon and local rehabilitation clinics in Iksan from 1. July. 1995 to 31. Jun. 1996. We evaluated activites of daily living by using modified Barthel Index(MBI) and classified them into dependent group with 60 points or less(6roup I ), and independent group with more than 60 points(Group II). We also used Family APGAR score and FACES III to evaluate their family functions. RESULTS: MBI scores to evaluate ADL were 42.9+/-15.6 in Group I and 82.1+/-17.9 in Group II. Family APGAR scores were 6.93+/-2.52 in Group I and 7.24+/-17.9 in Group II but there was no significance between two groups. Types of family according to Family APGAR score were highly functional, morderate dysfunctional, and severly dysfunctional one in order of frequency in both groups, but there was no significance in their frequencies in both groups. Types of Family in view of cohesion was disengaged, separated, connected, and enmeshed one in order of frequency in Group I, and separated, disengaged, connected, and enmeshed one in order of frequency in Group II but there was no significance between two groups. Types of family in view of adaptability were rigid, chaotic structured,and flexible one in order of frequency in Group I, and were flexible, structured, rigid, and chaotic one in orders in Group II, which showed significance between two groups. Extremal types of family structure were large in numbers in Group I, but it didnt show significance. CONCLUSIONS: Assuming that there were large numbers of rigid and chaotic family in Group I, it is considered that tne family which has a patient with severely impaired function seems to have weaker adaptability to their family stresses than otherwise. Therefore, it is desirable that physicians who take charge of such patients provide continuous and comprehensive medical care for them including their family with greater concerns and through analysis and assessment of their family functions.
Activities of Daily Living
;
Apgar Score
;
Daejeon
;
Humans
;
Inpatients*
;
Jeollabuk-do
;
Rehabilitation*
;
Solar System
10.Segmental Spinal Instrumentation in the Management of Fracture and Fracture-Dislocation of the Thoraco-Lumbar Spine
Hyun Oh CHO ; Young Goo LEE ; Pan Suck KIM ; Sang Sun LEE ; Bong Yul LIM
The Journal of the Korean Orthopaedic Association 1985;20(1):69-76
Segmental Spinal Instrumentation(S.S.I.) is more effective means of managing unstable thoraco-lumbar spine fractures than traditional Harrington Rod Instrumentation as an operative procedure which afforded rigid internal fixation with stability and needed minimal external immobilization. Early return to normal activity and successful rehabilitation are facilitated by efficient stabilization with S.S.I. Fifty-nine patients with fractures and fracture-dislocations of thoraco-lumbar spine were treated by Harrington Rod Instrumentation (29 patients) and S.S.I. (30 patients) at this hospital from June 1979 to July 1984. We have analysed the results of these treatment and obtained following conclusions: 1. S.S.I. is more rigid internal fixation than Harrington Rod Instrumentation. a) no or minimal external immobilization b) early ambulation and rehabilitation c) lowered complications 2. There was no significant difference in correction rate, loss of correction, and neurologic recovery between Harrington Rod Instrumentation and S.S.I.
Early Ambulation
;
Humans
;
Immobilization
;
Rehabilitation
;
Spine
;
Surgical Procedures, Operative