1.A Case of Angioleiomyoma on the Lip.
Hyun Jeong PARK ; Young Min PARK ; Jong Yuk YI ; Tae Yoon KIM ; Chung Won KIM
Annals of Dermatology 1996;8(1):57-60
It is known in general that neoplasms of smooth mucsle appear very rarely in the oral region, probaly because in the oral region with histopathologic investigations have been reported. This report presents an unusual case of angioleiomyoma that developed on the lower lip of a 48-year the course of one year and the immunohistochemical findings of the angioleiomyyoma are described.
Angiomyoma*
;
Lip*
2.Congenital Duodenal Web in a Young Adult.
Hwan Hyo LEE ; Hyung Guk KIM ; Young Yuk YOON
Journal of the Korean Surgical Society 2003;64(4):343-347
Congenital duodenal web in adult life is an extremely rare condition, which results from an incomplete recanalization of the duodenum during early embryologic development. We report a case of congenital duodenal web in a 23-year-old man who complained of postprandial epigastric pain and fullness, as well as nausea since childhood. The plain abdomen showed a double-bubble sign. The UGI study showed a marked dilatation of the proximal duodenum and a delayed passage of barium into the third portion of the duodenum. Abdominal ultrasonography and CT revealed a marked dilatation of the proximal duodenum and a duodenal web with windsock deformity, which originated from the ampulla of Vater and extended to the third portion of the duodenum. A winsock web with a 0.9 cm eccentric aperture and a healed ulcer proximal to the ampulla of Vater were observed during a longitudinal duodenotomy. The web was excised circumferentially and the duodenum was closed transversely in a Heineke-Mikulicz fashion.
Abdomen
;
Adult
;
Ampulla of Vater
;
Barium
;
Congenital Abnormalities
;
Dilatation
;
Duodenum
;
Humans
;
Nausea
;
Ulcer
;
Ultrasonography
;
Young Adult*
3.A Case of Trichilemmal Carcinoma.
Hong Jin PARK ; Young Min PARK ; Jong Yuk YI ; Tae Yoon KIM ; Baik Kee CHO ; Chung Won KIM ; Seok Jin KANG
Annals of Dermatology 1996;8(1):61-65
We report a case of trichilemmal catcinoma in a 79-year-old woman presentde an atrophic scar remaining after excision of a recurrent nodule on the right mandibular area, Her past history revealed that there had been a painful pea-sized brownish nofule on the same site for two years. Eleven months before presentation, it had been excised but recurred 9 months later. Histopathologic findings showed a clear cell neoplasm with trichilemmal keratinization. The tumor cells showed PAS-positive cytoplasm and cytologic atypia with a few mitoitic figures. Immunohistochemical staining for high molecular weight cytokeratin was positive but carcinoembryonic antigens and epithelial membrane antigens were all negative. To our knowledge this is the first report of trichilemmal carcinoma in Korea.
Aged
;
Carcinoembryonic Antigen
;
Cicatrix
;
Cytoplasm
;
Female
;
Humans
;
Keratins
;
Korea
;
Molecular Weight
;
Mucin-1
4.Two Cases of Congenital Preauricular Fistula.
Koo Seog CHAE ; Young Min PARK ; Jong Yuk YI ; Tae Yoon KIM ; Chung Won KIM
Korean Journal of Dermatology 1996;34(3):450-453
The auricle develops from six auricular tubercles which originate from the mesenchyme of the first and second branchial arch. If a defective fusion of these tubercles occur, a preauricular fistula may be formed. We report two cases of congenital preauricular fistula manifested by soft nodules with external openings on the left preauricular area. Histologically, the fistulas are lined by stratified squamous epithelium, and elastic cartilage. and chronic inflammatory cell infiltration are also present.
Branchial Region
;
Elastic Cartilage
;
Epithelium
;
Fistula*
;
Mesoderm
5.Malignant Peripheral Nerve Sheath Tumor Arising from Neurofibromatosis.
Seog Jun HA ; Young Min PARK ; Jong Yuk YI ; Tae Yoon KIM ; Chung Won KIM ; Jung Yong LEE ; Seok Jin KANG
Annals of Dermatology 1996;8(2):153-157
A 65-year-old woman complained of a pedunculated, huge mass on the anterior chest associated with neurofibromatosis type 1. The clinical and histological data showed the possibility of a malignant peripheral nerve sheath tumor. On electron microscopy, we found the characteristic findings of a malignant peripheral nerve sheath tumor, such as the foci of en-tangled cytoplasmic processes, undifferentiated spindle cells having large pleomorphic nuclei with prominent nucleoli, distinct basal cell lamina, rudimentary cell junctions, intermediate filaments and clumps of glycogen in the tumor cells. We, herein, report a case of malignant peripheral nerve sheath tumor arising from neurofibromatosis, studied by electron microscopy.
Aged
;
Cytoplasm
;
Female
;
Glycogen
;
Humans
;
Intercellular Junctions
;
Intermediate Filaments
;
Microscopy, Electron
;
Neurofibromatoses*
;
Neurofibromatosis 1
;
Peripheral Nerves*
;
Thorax
6.A Case of Juvenile Dermatomyositis Treated with Intravenous Gammaglobulin.
Hyun Jeong PARK ; Young Min PARK ; Jong Yuk YI ; Tae Yoon KIM ; Chung Won KIM
Korean Journal of Dermatology 1996;34(4):656-659
Dermatomyositis is an inflammatory muscular disease of presumed autoimmune origin. Many possible interventions are available to treat patients with these conditions including corticosteroids, immunosuppressive drugs, plasnapheresis, and total body irradiation. But these therapies are not always effective, and they may be associated with certain serious side effects. Recently polyvalent. intravenous gammaglohulin(IVGG) has been tried with success in inflammatory myopathies after failure of traditional treatment We report a 8-year-old female patient with juvenile dermatomyositis who improved dramatically after alternative IVGG treatment due to side effects of steroid.
Adrenal Cortex Hormones
;
Child
;
Dermatomyositis*
;
Female
;
Humans
;
Muscular Diseases
;
Myositis
;
Whole-Body Irradiation
7.Leprous Neuropathy Associated with Predominant Proprioceptive Sensory Loss.
Tae Kwan YOON ; Hee Young JO ; Ji Won YUK ; Jin Hong SHIN ; Dae Seong KIM
Korean Journal of Clinical Neurophysiology 2013;15(1):19-23
Some patients with leprosy may present with atypical features, such as isolated peripheral neuropathy without skin lesions, or marked proprioceptive dysfunction. We report a 56-year-old female who presented with predominant proprioceptive loss without skin lesion, but was finally confirmed as leprous neuropathy by sural nerve biopsy. It is postulated that large myelinated fibers were affected by chronic immunological reactions triggered by inactive bacterial particles, producing a peripheral neuropathy presenting as predominant proprioceptive sensory loss without typical skin lesions.
Biopsy
;
Female
;
Humans
;
Leprosy
;
Myelin Sheath
;
Organic Chemicals
;
Peripheral Nervous System Diseases
;
Proprioception
;
Skin
;
Sural Nerve
8.Experience on Early Urethral Catheter Removal Following Radical Prostatectomy.
Hyeong Dong YUK ; Gyoohwan JUNG ; Min Young YOON ; Juhyun PARK ; Sung Yong CHO ; Hwancheol SON ; Hyeon JEONG
Korean Journal of Urological Oncology 2016;14(2):76-81
PURPOSE: To assess outcomes from patients who underwent radical prostatectomy and had their indwelling urinary catheter removed on postoperative day (POD) 4 or 7. MATERIALS AND METHODS: The medical records of 107 consecutive patients receiving radical prostatectomy (RP), were retrospectively reviewed. Patients were categorized into two groups according to length of catheterization. Group 1 (n=40) had the urethral catheter removed on postoperative day (POD) 4, and group 2 (n=67) had the catheter removed on POD7. Group 1 had urethral catheter removal following no leakage on intraoperative leak testing and POD4 cystography, whilst group 2 exhibited leakage at POD4 and instead had routine POD7 urethral catheter removal if there was evidence of no leakage of POD7 cystography. Incontinence was checked according to the use of protective pad. RESULTS: The mean age of the study population was 67.0 years. acute urinary retension (AUR) following catheter removal occurred in 6 of the cohort (5.6%); 3 patients (7.5%) from group 1 and 3 (4.5%) from group 2 (p=0.669). The overall continence rate was 39.3%, 68.2%, 80.4%, and 91.6% at 1, 3, 6, and 12 months respectively. Importantly, the incontinence recovery pace of group 1 was notably higher than that of group 2 (p=0.001). Neither group exhibited bladder neck contracture. Intraoperative factors influencing the decision to remove catheter at POD4 following RP, are bladder neck reconstruction (OR=3.792, p=0.010) and nerve sparing (OR=6.646, p=0.008). CONCLUSIONS: Selective early urethral catheter removal may shorten the length of incontinence recovery, without increasing the risk of AUR and bladder neck contracture.
Catheterization
;
Catheters
;
Cohort Studies
;
Contracture
;
Humans
;
Medical Records
;
Neck
;
Prostatectomy*
;
Prostatic Neoplasms
;
Retrospective Studies
;
Urinary Bladder
;
Urinary Catheters*
9.Bilateral Renal Artery Stenosis with Renal Insufficiency: Successful Angioplasty Using Gadopentetate Dimeglumine as a Contrast Agent.
Sook Hee HONG ; Ha Hun SONG ; Sun Ae YOON ; Young Ok KIM ; Sung Jin MOON ; Young Soo KIM ; Ki Yuk CHANG ; Yoon Sik CHANG ; Byung Kee BANG
Korean Journal of Nephrology 2003;22(5):602-607
With the increasing number of interventional angiographic procedures, iodinated contrast induced nephropathy has become an important cause of iatrogenic acute renal failure. Gadopentetate dimeglumine, gadolinium chelated by DTPA, are widely used in magnetic resonance imaging without adverse effect on renal function in patients with renal insufficiency. It also has sufficient radiographic density to allow visualization and has been described as an alternative contrast agent for angiography. Here we report a case of successful angioplasty using gadopentetate dimeglumine as a contrast agent in a patient with both renal artery stenosis and renal insufficiency. The patient had a history of iodinated contrast induced acute renal failure. Using this contrast agent, angioplasty was successfully performed and contrast induced acute renal failure did not occur after this procedure.
Acute Kidney Injury
;
Angiography
;
Angioplasty*
;
Gadolinium
;
Gadolinium DTPA*
;
Humans
;
Magnetic Resonance Imaging
;
Pentetic Acid
;
Renal Artery Obstruction*
;
Renal Artery*
;
Renal Insufficiency*
10.Role of STAT3 as a Negative Regulator in Mac2- Binding Protein Expression.
Yuk Pheel PARK ; Jong Tae KIM ; Young YANG ; Jong Seok LIM ; Do Young YOON ; Jong Wan KIM ; Hee Gu LEE
The Korean Journal of Laboratory Medicine 2008;28(3):230-238
BACKGROUND: Mac-2 binding protein (Mac-2BP) is a secreted glycoprotein from the culture fluid of several human cancer cells, especially breast, lung, and gastric cells. Mac-2BP plays a role in immune response and cell adhesion activity in patients with various cancer and infectious diseases. In this study, we attempted to identify the regulators of Mac-2BP expression at the transcriptional level. METHODS: To determine the effect of epidermal growth factor (EGF) to Mac-2BP expression in gastric cancers, we constructed the different lengths of Mac-2BP promoter plasmids and measured the promoter activity and Mac-2BP expression. In addition to investigating the role of signal transducer and activator of transcription3 (STAT3) or human telomerase reverse transcriptase (hTERT) as a regulator of Mac-2BP, we transfected the small interfering RNA (siRNA) specific for STAT3 or hTERT, and Mac-2BP level was observed by a quantitative ELISA. RESULTS: EGF treatment could suppress the Mac-2BP transcription in HEK293 or gastric cancer cell lines (SNU-638 or AGS). In 5'-deleted promoter experiment, pGL3-Mac Pro-2377 transfected cells showed a decreased luciferase activity compared to pGL3-Mac Pro-2277. We also identified that (-2,366/-2,356) on Mac-2BP promoter is a putative STAT3 binding site and suppression of STAT3 with STAT3 specific siRNA increased the Mac-2BP level, suggesting the role of STAT3 as a negative regulator, in contrast to hTERT, which is known as a positive regulator. CONCLUSIONS: EGF signal is critical for the Mac-2BP expression, and more importantly, STAT3 could work as a negative regulator, while hTERT as a positive regulator in Mac-2BP transcription.
Antigens, Neoplasm/genetics/*metabolism
;
Cell Line
;
Cell Line, Tumor
;
Down-Regulation
;
Epidermal Growth Factor/metabolism
;
Humans
;
Membrane Glycoproteins/genetics/*metabolism
;
RNA, Small Interfering
;
STAT3 Transcription Factor/genetics/*metabolism
;
Telomerase/metabolism
;
Transfection