1.Inhibitory effects of several drugs to intestinal secretory stimulation of heat-labile enterotoxin produced by enterotoxigenic E. coli.
Kyung Rae MOON ; Sang Kee PARK ; Young Wook CHUN ; Kap Seung KIM ; Young Bong PARK
Journal of the Korean Pediatric Society 1991;34(9):1231-1239
No abstract available.
Enterotoxigenic Escherichia coli*
;
Enterotoxins*
2.A Case of Chronic Pancreatitis with Pancreatic Stones in Childhood.
Young Kyoo SHIN ; Chan Wook WOO ; Kee Hyoung LEE ; Young Chang TOCKGO ; Chang Duck KIM
Journal of the Korean Pediatric Society 1995;38(7):1012-1017
No abstract available.
Pancreatitis, Chronic*
3.The Changes of Ventricular Activation Time According to Acute Myocardial Ischemia.
Seong Wook HAN ; Yoon Nyun KIM ; Ki Young KIM ; Chang Wook NAM ; Kee Sik KIM ; Kwon Bae KIM
Korean Circulation Journal 2001;31(3):317-326
BACKGROUND AND OBJECTIVES: In acute myocardial ischemia, the conduction velocity of action potential is decreased by several electrophysiological and physical factors. The ventricular activation time(VAT) is a time duration of electrical impulse propagating from endocardium to epicardium. The goal of this study is to determine whether the reduction in conduction velocity in acute myocardial ischemia can lead a change in VAT. MATERIALS AND METHOD: Thirty patient, 18 males and 12 females, who had received percutaneous balloon coronary angioplasty(PTCA) were enrolled. The mean age was 59 years old. A twelve lead surface electrocardiogram(ECG) were obtained before, during, 1 minute, 5 minutes, and 10 minutes after the PTCA as digitized data by using Cardiolab EP 4.1 program. The magnitude of the QRS wave was amplified 3 to 4 folds and the speed was increased to 200mm/sec in order to get the VAT easily and accurately. The data was the mean of three consecutive VATs. The number of vessel treated with PTCA included left anterior descending artery(12), left circumflex artery(9), and right coronary artery(9). Among twelve chronic stable angina, sixteen unstable angina, and two acute myocardial infarction patients, twenty six had single and four had two vessel diseases. RESULTS: The significant increase in VAT during PTCA compared to that before PTCA was observed in eight of 12 leads. In addition, the significant decrease in VAT of 1, 5, and 10 minutes after PTCA compared to that during PTCA were noted. Furthermore, 10 minutes after PTCA, VAT decreased significantly compared to that before PTCA. The leads did not show a significant change of VAT depending on target vessels. The ECG of 16 patients showed changes of the ST segment during PTCA. The changes of VAT were not related to the ST segment change. CONCLUSION: The conduction delay from endocardium to epicardium in acute myocardial ischemia was presented as a prolongation of VAT in surface ECG. In addition, the conduction delay was recovered within 5 minutes after relief of ischemia. Therefore, the changes of VAT can possibly be used as one of the noninvasive parameters of myocardial ischemia.
Action Potentials
;
Angina, Stable
;
Angina, Unstable
;
Electrocardiography
;
Endocardium
;
Female
;
Humans
;
Ischemia
;
Male
;
Middle Aged
;
Myocardial Infarction
;
Myocardial Ischemia*
;
Pericardium
;
Thoracic Surgery, Video-Assisted
4.A Clinical Study of Reye`s Syndrome.
Young Seo PARK ; Hwan Jong LEE ; Sang Pok SUK ; Jeong Kee SEO ; Kwang Wook KO
Journal of the Korean Pediatric Society 1984;27(11):1088-1096
No abstract available.
5.A Case of Motor Paralysis of the Limb caused by Herpes Zoster.
Jin Seok YANG ; Hang Wook CHANG ; Jun Young LEE ; Baik Kee CHO
Annals of Dermatology 2001;13(4):243-246
Segmentally distributed cutaneous eruptions and neuralgia are common manifestations of herpes zoster. However, motor loss is another aspect of this manifestation, which is less well known and considered a rare finding. In many cases the loss of motor function may be easily overlooked because the pain is the more prominent feature and the weakness probably goes unrecognized with only a mild impairment of the motor function. We experienced a 71-year-old male patient with a herpes zoster-related motor paralysis of right arm whose clinical features of a weak limb mimicked other spinal motor diseases and confirmed motor involvement using electromyographic (EMG) and motor nerve conduction velocity (MNCV) studies.
Aged
;
Arm
;
Extremities*
;
Herpes Zoster*
;
Humans
;
Male
;
Neural Conduction
;
Neuralgia
;
Paralysis*
6.A Case of Eosinophilic Folliculitis after Allogenic Bone Marrow Transplantatino in Acute Myelogenous Leukemia.
Hang Wook CHANG ; Shin Taek OH ; Jun Young LEE ; Baik Kee CHO
Annals of Dermatology 2001;13(4):235-238
Eosinophilic folliculitis (EF) is regarded as a variant of eosinophilic pustular folliculitis (EPF), because it has a few distinctive clinical features different from those of EPF. EF is generally associated with systemic disorders, such as acquired immunodeficiency syndrome (AIDS) and hematologic malignancies. We have recently experienced a case of EF occurring in a 40 year-old male patient treated with allogenic bone marrow transplantation (BMT) for acute myelogenous leukemia(AML) and achieved a good clinical outcome after a short course of systemic corticosteroid therapy. The immunologic aberration resulting from systemic diseases may play a role in the development of EF.
Acquired Immunodeficiency Syndrome
;
Bone Marrow Transplantation
;
Bone Marrow*
;
Eosinophils*
;
Folliculitis*
;
Hematologic Neoplasms
;
Humans
;
Leukemia, Myeloid, Acute*
;
Male
7.Resting and Acetazolamide-Challenged Technetium 99m-ECD SPECT in Transient Global Amnesia.
Byong Soo SHIN ; Kee Won KIM ; Man Wook SEO ; Young Hyun KIM
Journal of the Korean Geriatrics Society 2003;7(1):65-74
BACKGROUND AND OBJECTIVE: Transient global amnesia(TGA) is a neurological syndrome affecting preferentially middle-aged or elderly people and characterized by sudden onset of transient impairment of antegrade amnesia with variably retrograde amnesia. TGA was defined over 30 years ago, but the etiology remain unclear. Several mechanisms have been proposed, including arterial thromboembolic ischemic attacks in both posterior cerebral artery territories, epilepsy, and migraine. Although many studies have reported TGA, only a few reported cerebral perfusion studies using SPECT because of the brief duration of the episode. Technetium-99m-ethyl cysteinate dimmer(ECD) is superior to sensitivity of lesion detection and lesion to normal contrast, probably due to lower back diffusion from the brain to the blood and its excellent radiochemical stability. So we evaluate pathophysiologic mechanism of TGA by using 99mTC-ECD SPECT with or without acetazolamide(ACZ) stress. METHODS: We evaluated six patients with transient global amnesia, four women and two men, age ranges 56 to 78 years, mean 62.2 years. Measurements of CBF and vascular reserve using 99mTC-ECD with or without ACD stress were performed during or after TGA episode. RESULTS: One patient, who was evaluated in TGA episode showed that regional cerebral blood flow was decreased in both anteroinferior frontal, both temporal, right thalamus, both inferior parietal and left parietal region with impaired vascular reserve in left inferior temporal and right thalamus. Others, who were evaluated more than 6days in TGA episode showed that regional cerebral blood flow was decreased in left temporal (4), both temporal region (1), left thalamus (2) and both basal ganglia (1) with preserved vascular reserve except one, showed impaired vascular reserve in left thalamus. CONCLUSION: This result show that severe hypoperfusion of bilateral temporal region and impaired vascular reserve in left temporal region in TGA episode. Other patients who were recovered from TGA showed hypoperfusion of left temporal region and preserved vascular reserve. 99mTc-ECD with acetazolamide SEPCT that sensitively detects localized impaired cerebraovascular reserve should help elucidate these processes. But further study with more cases is necessary for evaluation of pathophysiology of TGA.
Acetazolamide
;
Aged
;
Amnesia
;
Amnesia, Retrograde
;
Amnesia, Transient Global*
;
Basal Ganglia
;
Brain
;
Diffusion
;
Epilepsy
;
Female
;
Humans
;
Male
;
Migraine Disorders
;
Perfusion
;
Posterior Cerebral Artery
;
Rabeprazole
;
Technetium*
;
Thalamus
;
Tomography, Emission-Computed, Single-Photon*
8.A Case of Subcutaneous Granuloma Annulare.
Jun Young LEE ; Chun Wook PARK ; Baik Kee CHO ; Won HUGH ; Moon Jae CHO
Korean Journal of Dermatology 1986;24(2):288-291
We report herein a case of subcutaneous granuloma annulare occured in a 3-year-old girl who had 7 subcutaneous nodules on the scalp, lumbar area, buttock, right tibial area and both ankles. liistopathologically, multiple foci of complete and incomplete collagen degeneration surrounded by histiocytes in a palisading arrangement were seen in the subcutaneous layer. Some vessel walls were thickened and infiltrated with inflammatory cells and many eosinophils were scattered among the inflamrnatory cell infiltrate around the palisaiing granuloma. Five of the lesions disappeared spontaneously and other s decreased in size without specific treatment in 2 months.
Ankle
;
Buttocks
;
Child, Preschool
;
Collagen
;
Eosinophils
;
Female
;
Granuloma Annulare*
;
Granuloma*
;
Histiocytes
;
Humans
;
Scalp
9.A Case of Pruritic Urticarial Papules and Plaquesof Pregnancy.
Chun Wook PARK ; Young Whan KIM ; Baik Kee CHO ; Won HOUH
Korean Journal of Dermatology 1986;24(3):403-405
We report herein a case of PUPPP in a 26-year-old-primigravida with urticarial papules and plaques on the abdomen and thigh which developed at 39th week of the pregnancy. Histopathologic findings revealed focal spongiosis in the epidermis and lymphocytic perivascular infiltration in the dermis. The skin lesion resolved spontaneously after delivery and the new-born had no specific abnormalities.
Abdomen
;
Dermis
;
Epidermis
;
Pregnancy*
;
Skin
;
Thigh
10.A Case of Spindle Cell Lipoma.
Ki Wook LEE ; Jun Gyu JANG ; Young Soo CHAE ; Kee Suck SUH ; Sang Tae KIM
Korean Journal of Dermatology 1998;36(3):528-531
Spindle cell lipoma was first described in 1975 by Enzinger and Harvey as a variant of lipomas. Histopathological findings show the lipomatous tissue to be replaced by a mixture of uniform spindle cells and mature fat cells closely associated with a mucoid matrix and a varying number of collagen fibers. Immunohistochemical staining is reported to give assistance in the differential diagnosis af spindle cell lipoma from other fibrous or neural tumors. Also, it can be used to investigate the origin of the spindle cells. We report a case of spindle cell lipoma in a 41-year-old female. She had a solitary, normal skin colored, bean sized, subcutaneous mass on the forearm. Most of the spindle cells were strongly positive for vimentin, CD34 and NSE, but negative for actin, factor VIII, S-100 protein and neuro- filaments. The tumor was excised. No recurrence was recognized in a 10 month follow up period.
Actins
;
Adipocytes
;
Adult
;
Collagen
;
Diagnosis, Differential
;
Factor VIII
;
Female
;
Follow-Up Studies
;
Forearm
;
Humans
;
Lipoma*
;
Recurrence
;
S100 Proteins
;
Skin
;
Vimentin