1.Huge Peripelvic Lymphatic Cyst: A Case Report.
Kang Woo EUH ; Young Woo KONG ; Hi Chu SONG ; Kee Soo KIM
Korean Journal of Urology 1978;19(5):461-464
Peripelvic lymphatic cyst or the kidney is a rare case in Korean Urological literature. We have experienced a case of it in 30 years old woman who had a palpable fluctuant mass in the upper right quadrant of the abdomen. The operated cyst was dark-red colored appearance and filled with amber colored fluid about 800cc. We have removed it together with kidney. The cyst measured 200gm. in weight, 10 x 5 x 4.5 cm in size and 0.5cm thickness of the cystic wall. Histological finding of the cystic wall showed a consisting of endometrial cell underlying tissue was collagen fiber and fibrotic change. The fluid of cyst contained 98 % of lymphatic cell.
Abdomen
;
Adult
;
Amber
;
Collagen
;
Female
;
Humans
;
Kidney
;
Lymphocele*
2.A Statistical Study on Length of Prostatic Urethra in Korean Adult by Radiology.
Korean Journal of Urology 1979;20(2):161-165
What we know an actual length of the prostatic urethra is a valuable implement for evaluating on urological conditions of prostatic gland, such as the prostatic hyperplasia, prostatic tumor and other disorders of the prostatic gland. The urological discipline concerned with this, usually known nowadays as cystourethrography, has therefore a key position in evaluating of the length of prostatic urethra clinically. The author performed a cystourethrograph on 20 cases of Korean adults, and measured the length of prostatic urethra on urogram which was made by radiology with a metric system. Results are as follows: 1) Average length of the prostatic urethra on the antero-posterior view was 4.48+/-0.373 (M+/-S.D.) 2) On the right oblique view, average length of prostatic urethra was 4.80+/-0.403 (M+/-S.D.) 3) On the left oblique view, average length of prostatic urethra was 4.85+/-0.419 (M+/-S.D.)
Adult*
;
Humans
;
Metric System
;
Prostatic Hyperplasia
;
Statistics as Topic*
;
Urethra*
3.Lower Urinary Tract Injuries Associated with Pelvic Bone Fractures.
Chang Sik SHIN ; Young Woo KONG
Korean Journal of Urology 1982;23(2):221-224
A clinical study was made on 108 patients with pelvic bone fractures and 37 patients with lower urinary tract injury in the Capital Armed Forces General Hospital during the period of 3 years from January, 1978 to December, 1980. Emphasis was placed on the mechanism of the bladder and urethral injuries. The results were summarized as follows: 1. The most common cause of pelvic bone fractures was traffic accident (88.0%). 2. 37 cases (34.3%) of the pelvic bone fractures were associated with lower urinary tract injuries. These included 17 ruptures of the urethra, 14 bladder injury and 6 bladder and urethral injuries. 3. Among the total bladder injuries (20 cases), we found 14 extraperitoneal ruptures of the bladder. 4 intraperitoneal ruptures and 2 bladder contusion. 4. Among the 23 urethral injuries, membranous urethral injuries were prominent, 19 membranous urethral ruptures and 4 bulbous urethral ruptures.
Accidents, Traffic
;
Arm
;
Contusions
;
Hospitals, General
;
Humans
;
Pelvic Bones*
;
Rupture
;
Urethra
;
Urinary Bladder
;
Urinary Tract*
4.Clinical Observation on Gross Hematuria.
Baik Nam CHOI ; Young Woo KONG
Korean Journal of Urology 1982;23(1):78-82
A clinical observation was made on 199 cases of gross hematuria who were admitted to the Department of Urology. Capital Armed Forces General Hospital during the period from January, 1978 to December, 1980. The following results were obtained; 1. The incidence of gross hematuria was 27.5% of all urological in-patients and male to female ratio was 4.5:1. 2. The most frequent incidence of gross hematuria on male were trauma and calculus and infection on female. 3. The commonest disease of gross hematuria were ureteral stone, renal injury, renal stone and renal tuberculosis. 4. The most frequent incidence of gross hematurias were calculus and trauma under the age of 40 and tumor over the age of 40. 5. Etiology of gross hematuria were highest in calculi (30.7%), injury (27.6%), tumor (13.6%). 6. The sites of gross hematuria were it the kidney (48.2%), ureter (20.1%), bladder (17.6%). urethra (6.5%), prostate (3.0%). 7. Painless gross hematuria was 63.3% and the commonest cause was renal injury. Painful gross hematuria was 36.7% and the commonest cause was ureteral stone. 8. Total gross hematuria was 75.4% and the commonest causes were upper urinary tract lesions. Terminal gross hematuria was 21.2% and the commonest causes were mid urinary tract lesions. Initial hematuria was 3.4% and the commonest causes were lower urinary tract lesions.
Arm
;
Calculi
;
Female
;
Hematuria*
;
Hospitals, General
;
Humans
;
Incidence
;
Kidney
;
Male
;
Prostate
;
Tuberculosis, Renal
;
Ureter
;
Urethra
;
Urinary Bladder
;
Urinary Tract
;
Urology
5.Fast FLAIR MR Imaging Finidngs of Cerebral Infarction: Comparison with T2-Weighted Spin Echo Imaging.
Keun Young KONG ; Woo Suk CHOI ; Eui Jong KIM
Journal of the Korean Radiological Society 1997;37(1):9-15
PURPOSE: To evaluate the utility of FLAIR (Fluid Attenuated Inversion Recovery) MR imaging in cerebral infarction by comparing its results with those of T2-weighted spin-echo imaging. MATERIALS AND METHODS: We retrospectively evaluated fast FLAIR images and conventional spin echo images of 82 patients (47 men and 20 women; median age 60.9 years) with cerebral infarction. MR imaging used a 1.5T MR unit with conventional T2 (TR 3900, TE 90) and fast FLAIR sequence (TR 8000, TE 105, TI 2400). We analysed the size of the main lesion and number of lesions, and discrimination between old and new lesions and between small infarction and perivascular space. RESULTS: When T2-weighted and FLAIR imaging were compared, the latter showed that the main lesion was larger in 38 cases (46%), similar in 38 (46%), and smaller in six (7%). The number of lesions was greater in 23 cases (28%), similar in 52 (63%), and fewer in seven (9%). FLAIR images discriminated between old and new lesions in 31 cases ; perivascular space and small infartion were differentiated in eight cases, and CSF inflowing artifact was observed in 66 (80%). CONCLUSION: In the diagnosis of cerebral infaretion, fast FLAIR provides images that are equal or superior to T2-weighted images. The fast FLAIR sequence may therefore be used as a part of routine MR brain study in the diagnosis of cerebral infarction.
Artifacts
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Brain
;
Cerebral Infarction*
;
Diagnosis
;
Discrimination (Psychology)
;
Female
;
Humans
;
Infarction
;
Magnetic Resonance Imaging*
;
Male
;
Retrospective Studies
6.A Clinical Observation of Paratesticular Tumors.
Chong Kook LIM ; Young Woo KONG
Korean Journal of Urology 1982;23(4):546-549
A clinical observation was made on 19 cases of paratesticular tumors in 19 patients which were neither resolved nor improved with primary medical and conservative treatment in the Department of Urology. Capital Armed Forces General Hospital during the period from March, 1977 to July, 1981. The following results were obtained. 1. The age was ranged from 20 to 45 years old and the most favorable age was in 3rd decade. 2. The main symptoms and signs were palpable mass in 73.1%. 3. Duration of symptoms from onset was over 1 year in 57.9% and under 1 year in 42.1%. The mean duration was 17 months. 4. Organ distribution was 5 cases in epididymis, 5 in spermatic cord and 9 in scrotal tunics. 5. 11 cases arose on the left side, 4 on the right and 4 on the midline. 6. There were benign tumors in 17 (89.5%) and malignant tumors only in 2 (10.5%) of all 19 cases. These malignant lesions were developed in the spermatic cord. 7. The lesions were managed by local resection in 16 cases, orchiectomy in 2 and epididymectomy in 1.
Arm
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Epididymis
;
Hospitals, General
;
Humans
;
Male
;
Middle Aged
;
Orchiectomy
;
Spermatic Cord
;
Urology
7.Expressions of Epidermal Growth Factor Receptor, c-erbB-2 and p53 Protein as Useful Markers of Malignant Potential in a Transitional Cell Carcinoma of the Urinary Bladder.
Gu KONG ; Ki Yong SHIN ; Sun Jin KIM ; Young Hyeh KO ; Hae Young PARK ; Young Nam WOO ; Jung Dal LEE
Korean Journal of Pathology 1997;31(1):51-58
Transitional cell carcinoma(TCC) of the urinary bladder shows marked heterogeneity in biological behaviors. Evidence has accumulated that biological markers may provide significant information to predict the potential aggressiveness of TCC. We have assessed the expression of the epidermal growth factor receptor (EGF-R), c-erbB-2 and p53 proteins in 56 cases of TCC to investigate the prognostic significance of differential expression of these oncoproteins using an immunohistochemical method. We analysed the expression patterns of these oncoproteins according to tumor stage and grade. And we assessed the probability of progression-free survival in stage T1 tumors according to their expressions. Positive rates of EGF-R (>+3 staining intensity), c-erbB-2 (intense membrane staining) and p53 proteins (>20% positive cells) were 73.2%, 37.5% and 42.9%, respectively. Invasive tumors had significantly higher positive rates of all three factors than did superficial tumors (p<0.005 for EGF-R and c-erbB-2, p<0.05 for p53). High grade tumors had significantly higher positive rates of c-erbB-2 and p53 proteins (p<0.005). In superficial tumors, T1 tumors had higher positive rate of p53 protein compared with Ta tumors (p<0.05). Twelve cases of superficial tumors (34.3%) were positive for EGF-R and negative for c-erbB-2 and p53 proteins. Nine cases of superficial tumors(25.7%) were negative for all three factors. In invasive tumors, however, 42.5% of the cases were positive for all three factors. The overexpression of p53 protein was the only useful marker to predict the rapid progression in stage T1 tumors (p<0.05, log-rank test). These results suggest that the differential overexpression of EGF-R, c-erbB-2 and p53 proteins could be useful to depict tumor aggressiveness of TCC of the urinary bladder. And, the overexpression of a p53 protein may be a useful marker to predict the possibility of rapid progression in stage T1 tumors.
Biomarkers
;
Carcinoma, Transitional Cell*
;
Disease-Free Survival
;
Epidermal Growth Factor*
;
Immunohistochemistry
;
Membranes
;
Oncogene Proteins
;
Population Characteristics
;
Receptor, Epidermal Growth Factor*
;
Staphylococcal Protein A*
;
Urinary Bladder*
8.A Demonhstration of a Tracheal Bronchus by Bronchoscopy and Computed Tompgraphy.
Byoung Gu KONG ; Youn Kyung LEE ; Eun Young JEONG ; Woo Ki LEE ; Kwang Woo KIM ; Jung Kon KOH
Journal of the Korean Pediatric Society 2000;43(11):1501-1504
Tracheal bronchus is an aberrant bronchus that arises most often from the right tracheal wall above the carina and is the result of an additional tracheal outgrowth early in embryonic life. It; incidence ranges between 0.1 and 5%. This anomaly is usually diagnosed incidentally during bronchoscopy, bronchography or computed tomography. Occasionally, it represents the underlying etiology for chronic pulmonary disease, especially if it involves the right upper lobe and reflects an abnorrnal pulmonary clearing mechanism. The tracheal bronchus may be associated with other bronchopulmonary anomalies, tracheal stenosis, or Down's syndrome. Asymptornatic tracheal bronchus does not require any treatment. In case of tracheal bronchus associated recurrent right upper lobe diseases, tracheal bronchus therapy should include resection of the aberrant bronchus as well as the lob it supplies. (J Korgan Pediatr Soc 2000;43:1501-1504)
Bronchi*
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Bronchography
;
Bronchoscopy*
;
Down Syndrome
;
Equipment and Supplies
;
Incidence
;
Lung Diseases
;
Tracheal Diseases
;
Tracheal Stenosis
9.NAT2 Polymorphism and Individual Genetic Susceptibility to Colorectal Cancer Patients in Korea.
Young Seok PARK ; Kwang Soo LEE ; Kyu Young JUN ; Heung Woo LEE ; Ho Kyung CHUN ; Hyun Jun KIM ; Gu KONG
Journal of the Korean Society of Coloproctology 1998;14(2):155-164
To determine the frequencies of the genotypes of NAT2 gene in healthy Korean populations and to identify the high-risk genotypes of NAT2 gene in colorectal cancer patients, 115 healthy controls and 109 cancer patients were analyzed using polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP). The distribution of NAT2 polymorphism in healthy Korean was found to be 7.8% of S/S genotype, 48.7% of S/F genotype, and 43.5% of F/F genotype. And the frequency of phenotypes was 8% of slow acetylator and 92% of rapid acetylator. S/S genotype of colorectal cancer patients was slightly more frequent than that of healthy controls(11.9% vs 7.8%). The relative risk of S/S genotype to colorectal cancer was estimated to be 1.41, taking the risk of F/F genotype as a baseline(1.00). These results suggest that the distribution of frequencies of NAT2 genotypes is very unique in Korean characterized by extremely low frequency of slow acetylator geno type(S/S) in comparison to the other ethnic groups. And the slow acetylator genotype(S/S) in Korean was found to be more susceptible to colon cancer. Therefore, S/S genotype may have a certain role an colonic carcinogenesis in Korean.
Carcinogenesis
;
Colon
;
Colonic Neoplasms
;
Colorectal Neoplasms*
;
Ethnic Groups
;
Genetic Predisposition to Disease*
;
Genotype
;
Humans
;
Korea*
;
Phenotype
10.A Case of Familial Hemiplegic Migraine.
Young SA-KONG ; Bong Hwan LEE ; Sang Nam BAE ; Kyun Woo LEE ; Sang Ook NAM
Journal of the Korean Child Neurology Society 2003;11(2):367-371
Familial hemiplegic migraine(FHM) is an autosomal dominant subtype of migraine with aura, characterized by the occurrence of hemiplegia during the aura. Two subforms of FHM families exist; pure FHM in 80% and FHM families with cerebellar symptoms in 20%. Half of the known FHM families show genetic linkage to chromosome 19p13, and in these families FHM is caused by missense mutations in a neuronal P/Q type calcium channel alpha-1 subunit gene(CACNA1A gene). Linkages to 1q31 and 1q21-23 have also been established. Other families are linked neither to chromosome 19 nor 1. Clinical variabilities are partially associated with the various types of CACNA1A gene mutations. FHM is distinguished from more frequent migraine types by a clear, dominant inheritance pattern and the relative absense of other headache types. Further investigation of FHM will help to clarify the genetics of more common migraine. We describe a male patient with FHM with a brief review of the literature.
Calcium Channels
;
Chromosomes, Human, Pair 19
;
Epilepsy
;
Genetic Linkage
;
Genetics
;
Headache
;
Hemiplegia
;
Humans
;
Inheritance Patterns
;
Male
;
Migraine Disorders
;
Migraine with Aura*
;
Migraine without Aura
;
Mutation, Missense
;
Neurons