1.Development of diagnostic method of helicobacter pylori infection: I. molecular cloning and DNA sequencing of urease.
Cheol Keun PARK ; Woo Kon LEE ; Young Mi DOH ; Myung Je CHO ; Kwang Ho RHEE
Journal of the Korean Society for Microbiology 1991;26(6):541-552
No abstract available.
Cloning, Molecular*
;
DNA*
;
Helicobacter pylori*
;
Helicobacter*
;
Sequence Analysis, DNA*
;
Urease*
2.Percutaneous Automated Discectomy using Nucleotome in Lumbar Disc Herniations.
Young Soo KIM ; Sung Woo ROH ; Doh Heum YOON ; Young Eun CHO
Journal of Korean Neurosurgical Society 1994;23(6):625-629
The authors performed 19 cases of percutaneous automated discectomy using Nucleotome between Feb, 1988 and Jan, 1993. The mean age was 33 years ranging from 20 to 56 years. Eleven of the patients were men and eight were women. One level nucleotomy was done in 14 cases, two level in 4 cases and three level in 1 cases. Overall success rate was 63%. No intraoperative and postoperative complications occurred except transient back pain in 3 cases.
Back Pain
;
Diskectomy*
;
Female
;
Humans
;
Male
;
Postoperative Complications
3.Quality of Life and Insight in Patients with Schizophrenia.
Hee Jeong YOO ; Doh Jun YOON ; Young Woo SHIN ; Geonho BAHN ; Jong Woo KIM
Journal of Korean Neuropsychiatric Association 1999;38(2):340-348
OBJECTIVES: This study was designed to evaluate differences in the quality of life(QOL) according to insight in patients with schizophrenia. The author speculated that insight might have an effect on individual's QOL, especially subjective QOL. METHOD: The study group consisted of patients with schizophrenia(N=55). Subjects were divided into two groups, patients with insight(N=22)and without insight(N=15), based on Scale of Unawareness of Mental Disorders(SUMD). All of the patients were administered the Quality of Life Interview (QOLI)by Lehman and compared in objective and subjective QOL between two groups. Additionally, they completed BDI and F scale on MMPI. RESULTS: The patients with insight showed a tendency of lower scores in total subjective QOLI scores and the safety issues compared to the patients without insight although not significant statistically. And they showed significantly less satisfaction with social relations. In objective QOL, there are no statistically significant differences between two groups. CONCLUSION: Such differences support the notion that schizophrenic patients with insight are less satisfied with their lives, especially in the aspect of interpersonal relations. It reflects the awareness of functional decline due to lifetime disability, disconnection from social relations, poor resources and supports, social stigma, and also depressive or anxiety symptoms. The authors propose that the treatment strategies for schizophrenia must include concern and support for domains of life with which patients feel themselves least satisfied, to increase effectiveness and efficacy of treatment and improve QOL.
Anxiety
;
Humans
;
Interpersonal Relations
;
MMPI
;
Quality of Life*
;
Schizophrenia*
;
Social Stigma
4.Development of a diagnostic method of helicobacter pylori infection: II. detection of helicobacter pylori using polymerase chain reaction.
Cheol Keun PARK ; Woo Kon LEE ; Young Mi DOH ; Hyu Jin CHOI ; Myung Je CHO ; Hee Shang YOUN ; Kwang Ho RHEE ; Woo Hyun CHANG
Journal of the Korean Society for Microbiology 1992;27(1):45-58
No abstract available.
Helicobacter pylori*
;
Helicobacter*
;
Polymerase Chain Reaction*
5.Development of a diagnostic method of helicobacter pylori infection: II. detection of helicobacter pylori using polymerase chain reaction.
Cheol Keun PARK ; Woo Kon LEE ; Young Mi DOH ; Hyu Jin CHOI ; Myung Je CHO ; Hee Shang YOUN ; Kwang Ho RHEE ; Woo Hyun CHANG
Journal of the Korean Society for Microbiology 1992;27(1):45-58
No abstract available.
Helicobacter pylori*
;
Helicobacter*
;
Polymerase Chain Reaction*
6.A Study on the Changes in Left Ventricular Function by Experimental Coronary Artery Occlusion and Reperfusion.
Bong Kwan SEO ; Mun Hong DOH ; Joong Hyeon CHO ; Sun Il CHUNG ; Hyeon Ok LIM ; Sung Kyeong WOO ; Cheol Ho KIM ; Byung Hee OH ; Young Woo LEE
Korean Circulation Journal 1990;20(1):98-107
In order to observe the changes in left ventricular function during coronary artery occlusion and reperfusion, left anterior descending (LAD) coronary arteries in the anesthetized dogs were occluded for 1 hour and then reperfused for 4 hours. Hemodynamic indexes of global systolic and diastolic function and regional wall thickness changes as a regional contractile index were measured during occlusion and reperfusion. The results were as follows; 1) Indexes of global systolic function (left ventricular peak systolic pressure, peak positive dP/dt) and global diastolic function (peak negative dP/dt, time constant, left ventricular end-diastolic pressure) showed deterioration in early occlusion period (10-30 minutes) but gradually improved even if coronary occlusion persisted. Reperfusion did not induce significant changes except that peak positive dP/dt transiently deteriorated 30 minutes after reperfusion and left ventricular end-diastolic pressure decreased 1.5-2 hours after reperfusion. 2) Indexed of regional function (i.e, end-diastolic thickness and % systolic thickening of anterior left ventricular wall) deteriorated by 10 minutes' occlusion which persisted during the entire occlusion period. Reperfusion induced no significant improvement in regional contractile function compared with occlusion 60 minutes' data, which suggested reperfusion for 4 hours after 1 hour's LAD occlusion may be insufficient for the ischemic region to recover its contractility. 3) Reperfusion arrhythmia (ventricular tachycardia) was noted in most (6/9) of the dogs, one of which deteriorated into ventricular fibrillation and the others spontaneously converted to normal sinus rhythm.
Animals
;
Arrhythmias, Cardiac
;
Blood Pressure
;
Coronary Occlusion
;
Coronary Vessels*
;
Dogs
;
Hemodynamics
;
Reperfusion*
;
Ventricular Fibrillation
;
Ventricular Function, Left*
7.A Case of Pulmonary Vein Aneurysm Simulating Lung Tumor.
Moon Hong DOH ; Ha Jin IM ; Yu Ho KIM ; Byung Hee OH ; Young Bae PARK ; Yun Sihk CHOI ; Jung Don SEO ; Young Woo LEE ; Jae Hyung PARK
Korean Circulation Journal 1987;17(3):565-570
A case of pulmonary vein aneurysm is presented. Chest X-ray revealed round density along the right cardiac border in right lower lung field. The round density was suspected as solid tumor initially, but the angiocardiogram showed dealyed opacification of right inferior pulmonary vein. So it was confirmed as pulmonary vein aneurysm. This patient took mitral valve replacement because of mitral and aortic regurgitation. Pulmonary vein aneurysm is considered as congenital in origin and pulmonary venous hypertension has its pathogenetic role in enlarging the varix. Pulmonary vein aneurysm probably has little clinical significance although cases of spontaneous rupture have been reported. There are a few reported cases in the literature, but the actual incidence probably is much higher than reported. This is the first to be reported in Korean literature.
Aneurysm*
;
Aortic Valve Insufficiency
;
Humans
;
Hypertension
;
Incidence
;
Lung*
;
Mitral Valve
;
Pulmonary Veins*
;
Rupture, Spontaneous
;
Thorax
;
Varicose Veins
8.Clinical Observation of Cardiac Myxoma.
Chee Jeong KIM ; Moon Hong DOH ; Oh Hoon KWON ; Byung Heui OH ; Myoung Mook LEE ; Young Bae PARK ; Yun Shik CHOI ; Jung Don SEO ; Young Woo LEE
Korean Circulation Journal 1985;15(4):671-679
Cardiac myxoma is rare and has protean clinical manifestations mimicking various disease. Unless clinician has a high index of suspicion, the diagnosis can be easil missed. However diagnosis is all the more important since surgery can be dramatically successful, where as untreated myxoma invariably leads to death. Cardiac myxoma accounts for 50% of primary cardiac tumor and mainly originates in left atrium.(75%). The features of myxoma can be described under the three headings : Constitutional, obstructive, and embolic. From 1977 to 1985, the authors have experienced 30 cases of cardiac myxoma, one of which recurred. Of 29 patients, 8 were male and 21 were female. Their ages ranged from 11 to 55 years with average of 39.8 years. Constitutional manifestation was found in 25 of the 27 patients, obstructive manifestation in 27, and embolic phenomenon in 5. The diagnosis of myxoma was made on the basis of 2-D echocardiography. The sensitivity was 100%. Except 1 case who refused operation, all received surgical treatment. Immediate postoperative complication occurred in 6 patients(23%). Among them serious complication could be found only in 2 cases(7.7%). During long term follow up there was one recurrence and one patient with right ventricular myxoma has tricuspid regurgitation. In other cases, we could not found any problems.
Diagnosis
;
Echocardiography
;
Female
;
Follow-Up Studies
;
Head
;
Heart Neoplasms
;
Humans
;
Male
;
Myxoma*
;
Postoperative Complications
;
Recurrence
;
Tricuspid Valve Insufficiency
9.Changes of Doppler Echocardiographic Findings After Mitral Valve Operation.
Seung Jae JOO ; Min Su HYON ; Moon Hong DOH ; Cheol Ho KIM ; Byung Hee OH ; Young Bae PARK ; Yun Sik CHOI ; Jung Don SEO ; Young Woo LEE
Korean Circulation Journal 1987;17(4):649-660
Pulsed Doppler echocardiography was performed before and five to fifteen days (mean, 9.3 days) after mitral valve surgery to evaluate the change of pulmonary arterial pressure in 80 patients (29 males and 51 females) with mitral valve disease by preejection period (PEP)/acceleration time (AT) ratio at the right ventricular outflow tract. In 13 patients with pulmonary hypertension (mean pulmonary arterial pressure equal to or greater than 20mmHg), Doppler echocardiography was followed three to twelve months after operation. In 76 patients with a mitral valve prosthesis (15 patients with the Bjork-Shiley valve, 28 patients with the Ionescu-Shiley valve, and 33 patients with the St. Jude valve), mean transmitral pressure gradient and pressure-half time were estimated by continuous wave Doppler echocardiography five to fifteen days after operation. 1) PEP/AT Ratio by pulsed Doppler echocardiography correlated well with the mean pulmonary arterial pressure gradient by cardiac catheterization (r=0.83, p<0.001). 2) After mitral valve surgery, PEP/AT ratio decreased significantly (p<0.001). In group with mean pulmonary arterial pressure equal to or greater than 40mmHg, immmediate postoperative PEP/AT ratio was greater (P<0.05) than that in group with mean pulmonary arterial pressure less than 20 mmHg, but, difference between the preoperative and postoperative PEP/AT ratio was much greater (P<0.001) than that in group with mean pulmonary arterial pressure between 20 and 39 mmHg. 3) In 13 patients, on whom repeated Doppler echocardiography performed, PEP/AT ratio decreased immediately after mitral valve surgery (p<0.001). After then, it decreased further, but, the amount of the decrease was much smaller than immediate one (p<0.001). 4) There was no significant difference in postoperative PEP/AT ratio among the different prosthesis. Mean transmitral pressure gradient and pressure half-time of the Bjork-Shiley, Ionescu-Shiley, and St, jude valves were 3.1 mmhg and 67.3 msec, 2.9 mmHg and 65.3 msec, and 2.7 mmhg and 60.2 msec, repectively. The St.Jude valve had somewhat smaller mean transmitral pressure gradient and pressure half-time, but there was no statistical significance. In conclusion, elevated pulmonary arterial pressure in patients with mitral valve disease decreased greatly within 15 days after operation, and Doppler echocardiography was a useful method in the follow-up of prosthetic mitral valve function.
Arterial Pressure
;
Cardiac Catheterization
;
Cardiac Catheters
;
Echocardiography*
;
Echocardiography, Doppler
;
Echocardiography, Doppler, Pulsed
;
Follow-Up Studies
;
Humans
;
Hypertension, Pulmonary
;
Male
;
Mitral Valve*
;
Prostheses and Implants
10.Clinical Characteristics of Tuberculosis in North Korean Refugees.
Chang Min CHOI ; Woo Kyoung JEUNG ; Cheol In KANG ; Doh Hyung KIM ; Young Keun KIM ; Sang Taek HEO ; Hee Jin KIM
Tuberculosis and Respiratory Diseases 2006;60(3):285-289
BACKGROUND: North Korea's economic and public health problems began in the early 1990s as a result of the gradual loss of economic support from its communist allies, combined with an inordinate number of natural disasters. The decline in public health has increased the incidence of tuberculosis in North Koreans and refugees. This study investigated tuberculosis situation in North Korean refugees in order to prepare for the future impact of tuberculosis control in Korea. MATERIAL AND METHODS: From 2001 to 2005, tuberculosis patients among North Korean refugees who were diagnosed before or after arriving in South Korea, based on the official records of OO hospital, were enrolled in this study. The demographic and clinical data of the cases were evaluated retrospectively. RESULTS: A total of 42 TB cases were reviewed during the study period. Of these, 37 (88.1%) cases were pulmonary TB. based on the cases identified among the number of North Korean refugees' arriving each year, the annual incidence of pulmonary TB were 900 per 100,000 in 2004, 700 in 2003, The number of smear-positive patients was 20 (47.6%) and the number of culture-positive patients was 18 (42.9%). Of the M. tuberculosis isolates, 2 cases were found to be susceptible to all anti-TB drugs available, 4 were resistant to isoniazid, and 3 were multi-drug resistant. CONCLUSION: The prevalence of pulmonary TB in North Korean Refugees is high. In addition, North Korean refugees suffer from more severe tuberculosis in bacteriological and radiological aspects.
Disasters
;
Humans
;
Incidence
;
Isoniazid
;
Korea
;
Prevalence
;
Public Health
;
Refugees*
;
Retrospective Studies
;
Tuberculosis*