We report herein a case of impetigo hepetiformis treated with etretinate. The patient was 30 year old female in the 7th month of her second pregnancy, who had suffered from generalized coalesced pustular eruption with slightly itching and hurning sensation with fever on whole body except face, both had and foot. The euption began as an erythemations patch which developed pustules along the mar gin. I'here was extensian by the develupment of fresh peripheral pustules and coaleence of these patches. Histopathological findings showed hyperkeratosis, subcorneal spongiform pustule, spon,iosis in the epidermis and vascular proliferation in the devmis, She was treated successfully with etretinate for 4 weeks.
Acitretin ; Adult ; Epidermis ; Etretinate ; Female ; Fever ; Foot ; Humans ; Impetigo* ; Pregnancy ; Pruritus ; Sensation

No abstract available.
Carcinoma, Squamous Cell* ; Osteomyelitis

Authors review the clinical and histopathologic findings of 41 EIenoch-Schonlein purpur.a patients and attempt, to clarify the association between abnorma] urinary findings and anti-streptolysin 0(ASLO) titer and performed the direct immunofluorescence(',E)II) study on skin lesion to investigate the pathogenetic mechanim of renal involvement. The results were summarized as follows : 1. Ag(, distribution was form 3 month to 63 years and mean age was 18.9 years. male to female ratio was 1.2:1(22 males '. 19 females). 2. In he past history, there were preceding upper respora.tory infections in 25(61:o)patients and drug history in 10(24.3%)patients. 3. (linical manifestations in the order of frequency were as follows : arthralgia (60.9%), hematuria or albuminuria(43.8%), abdominal pain(21.9%), and positive occult: blood test(7.3%)in stool examination. 4. In the laboratory fiindings, leukocytosis was cleveloped in 14.6%, anemia in 2.4%, increased eryttrocyte sec1imentation zate in 12.3% increased ASLG titer in 43.9% of patients, and serum IgG was increased in 4 of 20(20.6)patierits, IgA in 4 of 21(19%)patients, IgM in 1fo 19(5.3o)patients. 5. Because correlation between increased A.LO titer ancl ahnoormal urinary findings wa.s high(x-test, p< 0.0,5), increased ASI,O titer may be inclicator of renal involvement. 6. DIF stuc].y was per formed in 34 patients. All showed positive reactiviy. IgG(17%), IgA(29.4% ), Clq(14.6%), C3(12.2% ), fibrinog.n(82.4%) were deposited around the vessel wall in a granular pattern. 7. There was statistically significant increase in mean serum IgG value in patients with abnormal urinary findings( t test, p < 0.05 ).
Anemia ; Arthralgia ; Female ; Hematuria ; Humans ; Immunoglobulin A ; Immunoglobulin G ; Immunoglobulin M ; Leukocytosis ; Male ; Purpura* ; Purpura, Schoenlein-Henoch ; Skin

The bacteria as well as the fungi can build up resistance against different kinds of drugs or can decrease in sensitivity to these drugs. Therefore it is necessary that we use the MIC test for acertain period of time to determine the right concentration of drug to use in therapy. The culturing of P. orbiculare was successful in 1951. Up until that time, there were few drugs available to use in the MIC test. So, treatment for Tinea versicolor was dependent upon ones previous experience in determining the drug's effective concentration. Therefore, we performed the MIC test of clotrimazole, sodium thiosulfate, selenium sulfide, propylene glycol against P. orbiculare. The diagnos is for Tinea versicolor in the patient was confirmed by using KOH smear and by the clinical manifeststion. The fungi were then isolated in a culture from an olive oil rich media Mixture of isolated fungus and olive oil was applied to the lateral side of a healthy male's right upper extremity. After one week, P. orbiculare was confirmed by wood lamp examination, KOH smear and culture. After confirmation of P. orbiculare, a variety of concentrated drugs were used. Then media, containing propylene glycol, sodium thiosulfate, selenium sulfide and clotrimazole with a small amount of olive oil was used in inoculations of 10 viable unit/ml of P.orbiculare in attempt to estblish the MIC test. Test results are as follows: l) Propylene glycol MIC Range; 12. 5mg/ml~7. 5mg/ml. 2) Sodium thiosulfate MIC Range; 500mg/ml~7. 5mg/ml. 3) Selenium sulfide MIC Range; l. 25mg/ml~0. 04mg/ml. 4) Clotrimazole MIC Range; 0. 5mg/ml~ 0. 0005mg/ml.
Bacteria ; Clotrimazole ; Fungi ; Humans ; Malassezia* ; Olea ; Propylene Glycol ; Selenium ; Sodium ; Tinea Versicolor ; Upper Extremity ; Wood ; Olive Oil

The dysplasitc melanocytic nevus(DMN) of the skin is an atypical-appearing melanocytic tumor characterized by intraepidermal atypical melanocytic preliferation. Clinically, DMN has a diameter greater than 5mm, ill-defined irregular borders, irregularly distributed pigmentation surrounded by erythems,. Histopat- hologically, there are numerous discrete nests of atypical melanocytes situated at the dermoepidermal junction of elongated rete ridges. In the dermis, concentric lamellar fibroplasia, lymphocytic infiltrates and neovascularization are noted. We report herein a case of DMN developed on the trunk of 31-year-old Korean male.
Adult ; Dermis ; Humans ; Male ; Melanocytes ; Nevus, Pigmented* ; Pigmentation ; Skin

Clear cell sarcoma of tendon and aponeuroses is slow growing and painless. It occur chiefIy in young adults, predominates in women and is most common in the region of the foot and knee. It is intimately bound to tendons or aponeuroses and is composed of srnall nest or aggregates of round or fusiform, pale staining cells showing prominent nucleoli. And it is tend to recur and to resuIt in eventual development of metastatic growth after a protracted clinical ccurs. Herein, we report a case of clear cell sarcorna of tendon anu aponeuross of metatarsophalangeal joint area between 2nd and 3rd light of left foot. The patient, 50-year-old female had a slow groving, asymptomatic, slightly eevated, emooth surfaced and normal skin colored mass for 2 years. Histopatholcigic tindings in dermis revealed nests of atypical polygonal or monotonous cells. Each cell had vesicular or hyperchrornatic nucleus with prominent nucleoli, occcasionally mitotic figure and abundant eosinophilic cytoplasm. For. treatment, transmetatarsal amputation was done.
Amputation ; Cytoplasm ; Dermis ; Eosinophils ; Female ; Foot* ; Humans ; Knee ; Metatarsophalangeal Joint ; Middle Aged ; Sarcoma, Clear Cell* ; Skin ; Tendons ; Young Adult

Juvenile xanthogranuloma(JXG) is a a benign histiocytic proliferative disorder most frequently seen in infants. The usual course is self-limited, but it may be a manifestation of juvenile chronic myeloid leukemia(JCML). In addition to JXG, some patient with JCML may have multiple cafe-au-lait spots and a family history of neurofibromatosis(NF). The association of JXG and cafe-au-lait spots in patients with JCML is of interest in light of description of otherwise healthy children with JXG who also had cafe-au-lait spots. We report herein a case of JXG in 18-month-old boy who also had multiple cafe-au-alit spots, which predated the JCML.
Cafe-au-Lait Spots ; Child ; Humans ; Infant ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive* ; Male ; Neurofibromatoses* ; Xanthogranuloma, Juvenile*

The connective tissue nevus represents a hamartoma of various components of dermal connective tissue elements, predominantly collagen, elastin, or glycosa minoglycan. Zosterriform connective tissue nevus, described by Steiner, in 1944, clinically shows grouped papules in a zosteriform band without extracutaneous manifestations of family history, and peculiar histopathologic findings. We experienced 3 cases of typical zosteriforrn connective tissue nevus developed on the flank area of 30-year-old male and 21-year-old male, and on the inguinal area of 15-year-old female.
Adolescent ; Adult ; Collagen ; Connective Tissue* ; Elastin ; Female ; Hamartoma ; Humans ; Male ; Nevus* ; Young Adult

No abstract available.
Humans ; Psoriasis* ; Siblings*

We report a case of elephantiasis neurofibromatosa in a 50-year-old female patient treated by in walking excision. She had difficulty in walking due to a huge mass on the abdomen. After surgical excision, she is leading a normal life and is very satisfied.
Abdomen ; Elephantiasis* ; Female ; Humans ; Middle Aged ; Neurofibromatoses* ; Walking