1.Surgical correction of secondary cleft lip nose deformity using vertical scar flap.
Mi Sun KIM ; Sang Kju KANG ; Jung Young SEO ; Min Sung TAK ; Young Bae KIM
Journal of the Korean Society of Aesthetic Plastic Surgery 2000;6(2):119-124
No Abstract Available.
Cicatrix*
;
Cleft Lip*
;
Congenital Abnormalities*
;
Nose*
2.Erratum: Acknowledgments. The Efficacy and Safety of Tadalafil 5 mg Once Daily in the Treatment of Erectile Dysfunction After Robot-Assisted Laparoscopic Radical Prostatectomy: 1-Year Follow-up.
Young Eun SEO ; Soo Dong KIM ; Tae Hyo KIM ; Gyung Tak SUNG
Korean Journal of Urology 2014;55(3):226-226
In this paper, acknowledgments section was omitted unintentionally.
3.Development of a Dysphagia Screening Test for Preterm Infants (DST-PI).
Kyoung Moo LEE ; Young Tak SEO
Annals of Rehabilitation Medicine 2017;41(3):434-440
OBJECTIVE: To explore both the early prediction and diagnosis of dysphagia in preterm infants as an important developmental aspect as well as the prevention of respiratory complications, we developed the simple and-easy-to-apply Dysphagia Screening Test for Preterm Infants (DST-PI) to predict supraglottic penetration and subglottic aspiration. METHODS: Fifty-two infants were enrolled in a videofluoroscopic swallowing study (VFSS) due to clinical suspicions of dysphagia. Thirteen items related to supraglottic penetration or subglottic aspiration were initially selected from previous studies for the DST-PI. Finally, 7 items were determined by linear logistic regression analysis. Cutoff values, sensitivity, specificity, and the area under the ROC curve (AUC) of the DST-PI for predicting supraglottic penetration or subglottic aspiration were calculated using a ROC curve. For inter-rater reliability, the kappa coefficient was calculated. RESULTS: Seven items were selected: ‘gestational age,’‘history of apnea,’‘history of cyanosis during feeding,’‘swallowing pattern,’‘coughs during or after feeding,’‘decreased oxygen saturation within 3 minutes of feeding,’ and ‘voice change after feeding.’ The Spearman correlation coefficient between the DST-PI and the penetration-aspiration scale (PAS) was 0.807 (p<0.001). The sensitivity and specificity at different cutoff values for detecting supraglottic penetration and subglottic aspiration were 96.6% and 76.9% at 3.25, and 88.9% and 75.8% at 6.25, respectively. CONCLUSION: The DST-PI is a valid and reliable dysphagia screening test for supraglottic penetration or subglottic aspiration in preterm infants that is easy to apply in a clinical context.
Cyanosis
;
Deglutition
;
Deglutition Disorders*
;
Diagnosis
;
Humans
;
Infant
;
Infant, Newborn
;
Infant, Premature*
;
Logistic Models
;
Mass Screening*
;
Oxygen
;
ROC Curve
;
Sensitivity and Specificity
4.The prevalence of HBsAg positive parturients in Korea.
Kyung SEO ; Sook Kyoung PARK ; Young Tak KIM ; Ok PARK
Korean Journal of Obstetrics and Gynecology 2005;48(9):2119-2124
OBJECTIVE: To study prevalence rate of HBsAg positive parturient women in Korea and compare different rates according to the locations of delivery. METHODS: Total 848 institutions which reported more than 100 deliveries during 2001, were included for this study. Designed questionnaire were used to study the numbers of HBsAg positive parturients and total deliveries. The survey was conducted by mail, telephone and visit. Total 279,734 deliveries (55.2% of estimated total deliveries) were obtained to complete the study. RESULTS: Prevalence rates of HBsAg positive parturient women in Korea were 3.23% and 3.3% in 2001 and 2002 respectively. Cheju area showed highest prevalence rates. Women delivering in urban area showed higher prevlance rate than those in rural area. CONCLUSION: Prevalence rates of HBsAg positive parturient women were 3.3% in 2001-2002 and the rates sustained around 3.5% since 1992 in Korea.
Female
;
Hepatitis B Surface Antigens*
;
Humans
;
Jeju-do
;
Korea*
;
Postal Service
;
Prevalence*
;
Surveys and Questionnaire
;
Telephone
5.A case of steroid induced myopathy and peripheral polyneuropathy in patient with iatrogenic Cushing syndrome.
Ji Hoon KIM ; Mi Jin KIM ; Young Tak SEO ; Kwang Hyun KIM ; A Young PARK ; Young Hwan HAM
Korean Journal of Medicine 2006;71(1):103-107
Myopathy is a well known side effect of corticosteroid therapy. We report a case of iatrogenic steroid therapy induced myopathy in a 79-year-old female who had taken steroids for more than three years due to treatment for degenerative osteoarthritis. She complained of severe proximal muscle wasting and lower extremities weakness. Also, she had typical features of Cushing syndrome such as moon face, buffalo hump and easy bruising. Needle electromyogram showed no abnormal spontaneous activities in both lower extremities, but peripheral nerve conduction study showed motor conduction defect of both deep peroneal and tibial nerves. And, low SNAP (sensory nerve action potential) of both superficial peroneal and sural nerves, which were compatible with peripheral polyneuropathy in both lower extremities. The muscle biopsy revealed a pronounced muscle fiber atrophy, fatty degenerative change and selective type 2 fiber depletion on ATPase staining in pH 9.4 buffer. She was treated isotonic exercise physical therapy and slowly improved. After three months later, she complained sudden onset of chest discomfort and died due to congestive heart failure.
Adenosine Triphosphatases
;
Aged
;
Atrophy
;
Biopsy
;
Buffaloes
;
Cushing Syndrome*
;
Female
;
Heart Failure
;
Humans
;
Hydrogen-Ion Concentration
;
Lower Extremity
;
Muscular Diseases*
;
Needles
;
Osteoarthritis
;
Peripheral Nerves
;
Polyneuropathies*
;
Steroids
;
Sural Nerve
;
Thorax
;
Tibial Nerve
6.Correction of Craniosynostosis Using Distraction Osteogenesis by Gradual Distraction.
Mi Sun KIM ; Sang Kju KANG ; Jung Young SEO ; Min Sung TAK ; Young Bae KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 2000;27(5):469-474
Craniosynostosis is the term that designates premature fusion of one or more sutures in either cranial vault or cranial base. Strip craniectomy had been recorded in the literature before the turn of the century, and remarkable improvements in the correction of the craniosynostosis have taken place. Various surgical methods including frontal bone advancement and cranial vault remodeling have been developed in an effort to correct craniosynostosis. However, the standardized surgical method has not yet been established. Distraction osteogenesis had been developed by Ilizarov to elongate bones without bone graft and the technique was developed so as to lengthen the long bones. Karp and McCarthy reported successful membranous bone lengthening with external devices and noted that cortical bone formed in the expanded area of the mandible. In the field of cranial vault, the technique has been successfully used by Sugawara and many efforts are made to improve cranial vault deformities. There are two possible modes of bone regeneration in case of patients for whom gradual distraction of cranial vault is performed. Bone regeneration of cranial vault may occur from the cut edges of calvaria(distraction osteogenesis) or from islands within the dura mater. We have experienced four patients with craniosynostosis who had undergone surgical correction using distraction device. Because we believed that latent period was not an important factor, we could early initiate distraction schedule. All patients obtained satisfactory results and no relapse was observed during the follow-up period. In conclusion, we believe that latent period would not be an important factor in distraction osteogenesis of cranial vault and the distraction osteogenesis by gradual distraction is useful for the correction of craniosynostosis.
Appointments and Schedules
;
Bone Lengthening
;
Bone Regeneration
;
Congenital Abnormalities
;
Craniosynostoses*
;
Dura Mater
;
Follow-Up Studies
;
Frontal Bone
;
Humans
;
Islands
;
Mandible
;
Osteogenesis, Distraction*
;
Recurrence
;
Skull Base
;
Sutures
;
Transplants
7.Influence of sarcopenia on clinical outcomes in peptic ulcer bleeding: a retrospective single-center analysis in Korea
Ji Hoon YU ; Hyun Tak LEE ; Seok Ki JANG ; Ah Young LEE ; Jun-young SEO
Clinical Endoscopy 2025;58(3):425-437
Background/Aims:
Peptic ulcer bleeding (PUB) is a major cause of nonvariceal gastrointestinal bleeding. As the older population increases, the prevalence of sarcopenia is also growing. Although sarcopenia influences the prognosis of various diseases, its association with clinical outcomes of PUB remains unknown. Therefore, this study aimed to explore this correlation.
Methods:
We retrospectively analyzed 2,050 patients who underwent esophagogastroduodenoscopy for suspected gastrointestinal bleeding between January 2014 and December 2021. Patients who underwent computed tomography scans were included for sarcopenia evaluation based on the psoas muscle index, defined as the total psoas area normalized by the square of the height of the patient. Sarcopenia was defined using specific cutoffs: ≤7.3 cm2/m2 and ≤5.1 cm2/m2 for men and women, respectively. The primary outcome measured was the 30-day mortality rate.
Results:
Out of 358 patients, 149 were diagnosed with sarcopenia. The 30-day mortality rate was significantly higher in patients with sarcopenia than in those without. Multivariate regression analysis revealed significant associations between sarcopenia, a high age, blood tests, and comorbidity score, and administration of inotropic agents with 30-day mortality.
Conclusions
Our study showed that the presence of sarcopenia, elevated comorbidity scores, and use of inotropes were associated with higher 30-day mortality rates. Considering that sarcopenia may influence the clinical outcomes in patients with PUB, it is crucial to manage patients with sarcopenia with particular care.
8.Influence of sarcopenia on clinical outcomes in peptic ulcer bleeding: a retrospective single-center analysis in Korea
Ji Hoon YU ; Hyun Tak LEE ; Seok Ki JANG ; Ah Young LEE ; Jun-young SEO
Clinical Endoscopy 2025;58(3):425-437
Background/Aims:
Peptic ulcer bleeding (PUB) is a major cause of nonvariceal gastrointestinal bleeding. As the older population increases, the prevalence of sarcopenia is also growing. Although sarcopenia influences the prognosis of various diseases, its association with clinical outcomes of PUB remains unknown. Therefore, this study aimed to explore this correlation.
Methods:
We retrospectively analyzed 2,050 patients who underwent esophagogastroduodenoscopy for suspected gastrointestinal bleeding between January 2014 and December 2021. Patients who underwent computed tomography scans were included for sarcopenia evaluation based on the psoas muscle index, defined as the total psoas area normalized by the square of the height of the patient. Sarcopenia was defined using specific cutoffs: ≤7.3 cm2/m2 and ≤5.1 cm2/m2 for men and women, respectively. The primary outcome measured was the 30-day mortality rate.
Results:
Out of 358 patients, 149 were diagnosed with sarcopenia. The 30-day mortality rate was significantly higher in patients with sarcopenia than in those without. Multivariate regression analysis revealed significant associations between sarcopenia, a high age, blood tests, and comorbidity score, and administration of inotropic agents with 30-day mortality.
Conclusions
Our study showed that the presence of sarcopenia, elevated comorbidity scores, and use of inotropes were associated with higher 30-day mortality rates. Considering that sarcopenia may influence the clinical outcomes in patients with PUB, it is crucial to manage patients with sarcopenia with particular care.
9.Influence of sarcopenia on clinical outcomes in peptic ulcer bleeding: a retrospective single-center analysis in Korea
Ji Hoon YU ; Hyun Tak LEE ; Seok Ki JANG ; Ah Young LEE ; Jun-young SEO
Clinical Endoscopy 2025;58(3):425-437
Background/Aims:
Peptic ulcer bleeding (PUB) is a major cause of nonvariceal gastrointestinal bleeding. As the older population increases, the prevalence of sarcopenia is also growing. Although sarcopenia influences the prognosis of various diseases, its association with clinical outcomes of PUB remains unknown. Therefore, this study aimed to explore this correlation.
Methods:
We retrospectively analyzed 2,050 patients who underwent esophagogastroduodenoscopy for suspected gastrointestinal bleeding between January 2014 and December 2021. Patients who underwent computed tomography scans were included for sarcopenia evaluation based on the psoas muscle index, defined as the total psoas area normalized by the square of the height of the patient. Sarcopenia was defined using specific cutoffs: ≤7.3 cm2/m2 and ≤5.1 cm2/m2 for men and women, respectively. The primary outcome measured was the 30-day mortality rate.
Results:
Out of 358 patients, 149 were diagnosed with sarcopenia. The 30-day mortality rate was significantly higher in patients with sarcopenia than in those without. Multivariate regression analysis revealed significant associations between sarcopenia, a high age, blood tests, and comorbidity score, and administration of inotropic agents with 30-day mortality.
Conclusions
Our study showed that the presence of sarcopenia, elevated comorbidity scores, and use of inotropes were associated with higher 30-day mortality rates. Considering that sarcopenia may influence the clinical outcomes in patients with PUB, it is crucial to manage patients with sarcopenia with particular care.
10.Pathologic Analysis of Endomyocardial Biopsies in Heart Transplantation.
Mee Hye OH ; Jeong Wook SEO ; Kook Yang PARK ; Young Tak LEE ; Yoon Seop JEONG ; Suk Keun HONG ; Joon Ryang RHO ; Byung Hee OH ; Sung Sook KIM
Korean Journal of Pathology 1998;32(2):104-114
Endomyocardial biopsy (EMB) is a valuable diagnostic procedure for the surveillance of cardiac allograft rejection. Interpretation of individual cases is still problematic due to variations of findings for grading of rejection and other associated lesions. We reevaluated an experience on endomyocardial biopsies to develop better diagnostic criteria for rejection and other complications. Immunohistochemical studies against cytokines were performed to assess the usefulness of the method for the diagnosis or researches. A total of 249 EMBs taken from 33 cardiac allograft recipients were reviewed. There were 25 males and 8 females. Dilated cardiomyopathy was present (24 cases) and valvular heart disease (4 cases), restrictive cardiomyopathy (3 cases) were also common conditions. We applied the grading system of the International Society for Heart Transplantation (ISHT) for the assessment of acute cellular rejection. Grades of 0, 1A, 1B, 2, 3A and 3B were 39.0%, 28.1%, 11.2%, 11.5%, 12.4% and 1.6% respectively, but 3.2% were inadequate. Thirty five episodes of grade 3A or 3B were present in 17 patients. The response to therapy was assessed using a next follow up biopsy, which revealed resolving or resolved rejection in 85% of patients. The intensity of immunohistochemical stains for IL-6 and TNF-alpha was increased in proportion to the histologic grade but Quilty lesion and cardiomyopathy also showed a positive reaction. The other pathologic findings were ischemic change, previous biopsy site, interstitial edema and fibrosis, and Quilty lesion. These findings showed usefulness of endomyocardial biopsy not only for the evaluation of cardiac allograft rejection but also for the diagnosis of associated cardiac lesions. Immunohistochemical study of the cytokines was related to the degree of inflammation rather than degree of rejection.
Allografts
;
Biopsy*
;
Cardiomyopathies
;
Cardiomyopathy, Dilated
;
Cardiomyopathy, Restrictive
;
Coloring Agents
;
Cytokines
;
Diagnosis
;
Edema
;
Female
;
Fibrosis
;
Follow-Up Studies
;
Heart Transplantation*
;
Heart Valve Diseases
;
Heart*
;
Humans
;
Inflammation
;
Interleukin-6
;
Male
;
Tumor Necrosis Factor-alpha