Epithelioma cuniculatum or plantar verrucous carcinoma shows a great tendency toward deep penetrating growth, resulting in numerous crypts filled with horny material and pus. We herein described a 44 year-old female who showed a warty, relatively round, brown to yellow colored protruding mass with many crypts filled with pus-like exudates, measuring 2.3 X 2.5 X 1.5 cm in size, and of 5 years duration. The biopsy specimen taken from the tumor mass revealed a deeply penetrating, well-differentiated squarnous cell carcinoma without nuclear anaplasia and individual cell keratinization.
Adult ; Anaplasia ; Biopsy ; Carcinoma* ; Carcinoma, Verrucous ; Exudates and Transudates ; Female ; Humans ; Suppuration

The clinical observation was done on 9 patients of incontinentia pigmenti(I,P.) who were seen at the Department of Dermatology, Chonnam University Hospital from January, 1970 through December, 1982. The incidence of I.P. patients among the population of Chonnam province was higher than 1/142,000 whereas the frequency of I.P. among the outpatients was 0.016% The sex of I.P. patients was all female and there was no cases showing faiailial occurrence. The onset of the cases were within 4 months after birth, 44%, being at birth and 89% being within 2 weeks after birth. The durations of first, second and third stages of I.P. patients were respectively 14 days, 15 days to 2 months, and 2 months to 10 months. The trunk and extremities were involved in 4 cases, and the extremities only were involved in 4 cases while the trunk only was involved in J case. The blood eosinophilia was observed in 2 cases among 7 cases, with their results being 18%, and 11% respectively. The biopsy examinations done in 7 cases at the time of their first visits revealed that 3 cases, 2 cases and 1 case respectively conformed to first, second and third stages with 1 case having first and second stages simu 1taneously. There was no I.P. patient showing the associated congenital abnorma- lity.
Biopsy ; Dermatology ; Eosinophilia ; Extremities ; Female ; Humans ; Incidence ; Incontinentia Pigmenti* ; Jeollanam-do ; Outpatients ; Parturition

Prosthetic replacement was performed in 31 patients (32 cases) with femoral neck fractures at National Medical Center from 1968 to 1981. We reviewed the records of 28 patients having Austin-Moore prosthetic arthroplasty in 29 cases, and of 3 patients having Thompson prosthetic arthroplasty; then obtained following results. l. Of the 31 patients, 23 were female and 8 were male. The left hip was involved in 20 patients, right in 10, and the both sides in one. 2. The age range was between 35 and 84 years, with the average age of 61.2 years. 74.2% of patients were older than 51 years of age. 3. The most common cause of fracture was slipping or fall (65.6%), and the fracture sites were subcapital in 11 (34.4%), transcervical in 12 (37.4%), and basilar in 3 (9.4%). 4. Three cases (9.4%) were operated within a week, and 21 cases (65.6%) more than 3 weeks after injury. Good results were obtained in fresh fracture which was operated within a week. 5. In comparing the blood loss in Moores and modified Gibson's surgical approaches, the average total loss by the former was 1,290 ml and 1,720 ml by the latter. 6. In complications, one case of fracture of the posterior rim of acetabulum with subsequent subluxation and two cases of fracture of the greater trochanter were notable as operative complicatiens. 7. In a follow-up study averaging 13.1 months, good to excellent results were obtained in 8 cases, fair in 6, poor or bad in 5, respectively.
Acetabulum ; Arthroplasty ; Female ; Femoral Neck Fractures ; Femur ; Femur Head ; Follow-Up Studies ; Hip ; Humans ; Male

No abstract available.
Female ; Laparoscopy* ; Methotrexate* ; Pregnancy ; Pregnancy, Ectopic*

Leiomyosarcoma arising in the skin is rare tumor, and diagnosis usually is made microscopically. After local excision, these lesions recur in large proportion of pat ients. The authors herein report a 53-year-old male with leiomyosarcoma appeared in the skin of the right forearm and presenting as a dark reddish colored, 5*6cm in diameter, superficial ulcerated single firm nodule with intermittent pain. Histopathological examination showed poorly circumscribed tumor consisting of interlacing bundles of spindle shaped smooth muscle cells in the middle and lower parts of the dermis. The nuclei were hyperchromatic, large, vacuolated, and irregular in shape. Electron microscopic findings revealed cytoplasmic organelles such as rough endoplasmic reticulum and mitochondria of malignant smooth muscle cells in the paranuclear area, Characteristic subsarcoelmmal caveolae and dense plaque were noted and myofilaments were distributed in the peripheral cytoplasm. The tumor did not recur in 10 months' follow-up.
Caveolae ; Cytoplasm ; Dermis ; Diagnosis ; Endoplasmic Reticulum, Rough ; Follow-Up Studies ; Forearm ; Humans ; Leiomyosarcoma* ; Male ; Middle Aged ; Mitochondria ; Myocytes, Smooth Muscle ; Myofibrils ; Organelles ; Skin* ; Ulcer

The authors studied 410 cases of strabismus patients who visited our clinic from 1973 to 1978 Among them, 170 cases of esotropia, 234 cases of exotropia and 6 cases of hypertropia were observed. The average age at the time of onset was 3.4 years in esotropia and 5.2 years in exotropia. Visul acuity in exotropia was relatively good. 0.7 or more visual acuity was 53 % in exotropia and 34.7 % in exotropia. Refractive status, hypertropia above 1.5D was 64. 2 % in esotropia, but, no specific correlation was found between exotropia and refractive status. The incidence of amblyopia was 33.1 % in esotropia and 19.7 % in exotropia. In accomodative esotropia, the patients with high AC/A ratio were treated with bifocal segment glasses. and the results were good.
Amblyopia ; Esotropia ; Exotropia ; Eyeglasses ; Glass ; Humans ; Incidence ; Strabismus* ; Visual Acuity

No abstract available.

No abstract available.
CA-125 Antigen* ; Female ; Pregnancy ; Pregnancy, Ectopic*

Empyema thoracis following pneumonia, intra-abdominal pathology, trauma, and surgical procedure continues to be a source of major morbidity and mortality. Thirty seven adult and eleven pediatric patients with empyema thoracis were treated at the University of Yeungnam Medical Center from May 1983 to November 1986. Age distribution ranged from 6 months to 72 years and showed a double-peaked curve with the highest incidence between 36 and 65 years and below 15 years of age. There were male predominance in patients above 16 years of age. The most common predisposing factors was impaired consciousness due to either alcoholism or head injury. The causes of empyema were as follows: pneumonia 64.6%, ling abscess 6.4%, intraabdominal pathology 6.4%, and surgical procedure 6.4%. The cardinal symptoms were fever, cough, chest pain, dyspnea, sputum, weight loss, anorexia, and night sweat in orders. Culture of empyema fluid were positive in 50% of patients. The isolated organisms were Gram-negative bacilli 33.3%, staphylococcus aureus 25%, and streptococcus 25%. The patients received antibiotics in conjunction with various invasive procedures: chest tube drainage 77.1%, decortications 6.3%, and repeated thoracentesis 10.3%. There were 4 deaths, 1 child and 3 adults, with an overall mortality of 8.3%.
Abscess ; Adult ; Age Distribution ; Alcoholism ; Anorexia ; Anti-Bacterial Agents ; Causality ; Chest Pain ; Chest Tubes ; Child ; Clinical Study* ; Consciousness ; Cough ; Craniocerebral Trauma ; Drainage ; Dyspnea ; Empyema* ; Fever ; Humans ; Incidence ; Male ; Mortality ; Pathology ; Pneumonia ; Sputum ; Staphylococcus aureus ; Streptococcus ; Sweat ; Thoracentesis ; Weight Loss

The purpose of this study was to evaluate the influence of high dose carbon tetrachloride (CCI4) on the hepatotoxic effect of dimethylnitrosamine (DMN) which induces acute hemorrhagic necrosis in liver. Rats were injected intraperitoneally DMN dissolved in physiologic saline by a dose of 40 mg/kg. For changes related to CCI⁴ pretreatment, rats were injected intraperitoneally CCI⁴ dissolved in olive oil by a dose of 0.4 mg/kg, and then injected DMN. The livers were extracted from the rats 3, 6, 12, 24, 48, 72, and 120 hours after CCI⁴ and/ or DMN injection. Liver tissues were examined with light and electron microscopes. The results were summarized as follows; Light microscopic findings: Severe centrilobular hemorrhagic necrosis developed from 12 hours after injection of DMN and continued to 120 hours. On injection of DMN after CCI4 pretreatment, Massive necrosis occurred early. But active regenerative changes were produced in 24 hours. In 120 hours, the liver recovered in almost normal appearance. The degree of necrosis in pretreated group was similar to that in DMN injection only, and the time of recovery was faster in pretreated group. Electron microscopic findings: The early change was mainly disorganization of RER in DMN injection, and clumping and vesicular dilatation of ER in injection of CCI4. In pretreatment group, the early change was similar in appearance with CCI4 group, but severer in degree. According to the results, it was revealed that acute toxic effect of DMN was recovered more rapidly in pretreatment group. Thus it was suggested that CCI4 had protective effect in DMN hepatotoxicity.
Animals ; Carbon Tetrachloride* ; Carbon* ; Dilatation ; Dimethylnitrosamine ; Hepatocytes* ; Liver ; Necrosis ; Olive Oil ; Rats