Essential palmar hyperhidrosis is a disease characterized by excessive perspiration on the palms and hands due to the hyperaction of sympathetic nervous discharge. In severe cases, excessive sweating is seen on the face, axilla, trunk, and soles. Several therapeutic modalities were applied but surgical resection of the sympathetic ganglion is the only curative method. Numerous open surgeries of the thoracic sympathetic ganglia for the treatment of palmar hyperhidrosis have been advocated, but they have also produced several complications. A new therapeutic technique for this disorder has been introduced by combining a thoracoscope and video system. Nowadays, thoracoscopic transthoracic sympathectomy is accepted as the treatment of choice for essential palmar hyperhidrosis. This technique is safe and easy. It also reduces the operating time and admission period. It has also very few complications. Compensatory hyperhidrosis on the trunk, back, and thigh, etc. is commonly an unwanted and unsolved complication after thoracic sympathectomy. Through my experience of thoracic sympathectomy, I thought that the incidence of compensatory hyperhidrosis was closely related to the extent of thoracic sympathectomy. So I restricted the extent of thoracic sympathectomy as a T2 sympathetic ganglion from September 1995. From Mar., 1989 To Aug., 1995, T2, T3 sympathetic ganglionectomies were performed for palmar hyperhidrosis patients and from Sept. 1995 T2 sympathetic ganglionectomies were performed. Using questionnaires, I compared these 2 groups. The results of this study are summarized as follows; 1) Using thoracoscopic transthoracic sympathectomy, operating time, admission period and complications could be reduced. 2) The risk of bleeding during the operation(especially bleeding from the hemiazygous vein) could be reduced in the T2 sympathectomy group. 3) The treatment effect of T2 sympathectomy is no different from T2, T3 sympathectomy for essential palmar hyperhidrosis. 4) The incidence of compensatory hyperhidrosis is less in the T2 sympathectomy group than in the T2, T3 sympathectomy group. From the above results, I concluded thoracoscopic transthoracic sympathectomy is the treatment of choice for essential palmar hyperhidrosis and the adequate extent for sympathectomy is T2 sympathetic ganglion.
Axilla ; Ganglia, Sympathetic ; Ganglionectomy ; Hand ; Hemorrhage ; Humans ; Hyperhidrosis* ; Incidence ; Surveys and Questionnaires ; Sweat ; Sweating ; Sympathectomy* ; Thigh ; Thoracoscopes

Six patients with medulloblastoma involving brain stem were treated with surgical excision, irradiation or chemotherapy consisting of ACNU, vincristine and procarbazine from 1982 to 1993. All 6 patients were treated by surgical excision. Chang's staging was from T3b to T4 and radiation therapy was done in 5 patients and chemotherapy was performed in 4 patients. Mena follow up period was 25 months(range 1 to 87 months). The result of treatment for medulloblastomas invading brain stem was unfavorable in general, but radiation therapy combined aggressive chemotherapy after surgical resection could show a good result in some cases.
Brain Stem ; Brain* ; Drug Therapy ; Follow-Up Studies ; Humans ; Medulloblastoma* ; Nimustine ; Procarbazine ; Vincristine

Essential palmar hyperhidrosis is a disease characterized by excessive sweating on palms and hands due to hyperaction of sympathetic nervous discharge. It develops severe hypothermia on both hands because of loss of surface heat by evaporation of the sweating. Numerous tests including starch-iodine test were used to detect sweating status. But they were complicated and unpleasant to patients. Digital infrared Thermographic Imaging(DITI) can show a thermal difference very clearly. We have used DITI not only for the diagnosis, but for planning of the operation and operative follow up of the disease since 1990. 343 cases of bilateral upper thoracic(T2 & T3) sympathetic ganglionectomy were performed from Mar. 1989 to Dec. 1996 in our spine center. Among them, open surgery with posterior midline approach were initially carried out in 54 cases and recently percutaneous endoscopic sympathectomy were carried out in 289 additional cases. Digital Infrared Thermographic Imaging has been taken pre and postoperatively in 339 cases. Preoperatively, severe hypothermia is noted in 96.2% in both hands and feet. Immediately after operation, the sweating ceased in all cases and marked hyperthermia was noted in both hands compared to preoperative status due to sympathetic denervation. DITI is more accurate and easier than any other method for diagnosis and evaluation of treatment effect in hyperhidrosis. DITI is simple, accurate, comfortable and objective diagnostic tool for hyperhidrosis patient.
Diagnosis ; Fever ; Follow-Up Studies ; Foot ; Ganglionectomy ; Hand ; Hot Temperature ; Humans ; Hyperhidrosis* ; Hypothermia ; Spine ; Sweat ; Sweating ; Sympathectomy

There is no single method of choice for urethroplasty in the hypospadias and the posterior urethral obstruction and for penoplasty in the paraffinoma. Surgeons must choose a suitable method according to the condition of each individual patient. Herein we experienced severe formed posterior urethral stricture after traffic accident, complicated or severe formed hypospadias and completely denuded penis due to paraffinoma on IV cases from March. 1990 to September. 1992 in our hospital. We used vascularized scrotal pedicle flaps for urethroplasty and penoplasty. So, we herein report that the vascularized scortal pedicle flap is better than the other flaps in vascularity and elasticity. In posterior urethral obstruction and pararfinoma, there is no considerable complication after the surgery using the flap, but in 14 cases or hypospadias, 2 cases of urethro-cutaneous fistulas, 3 cases of meatal stenosis and 1 case of skin necrosis were noted.
Accidents, Traffic ; Constriction, Pathologic ; Elasticity ; Female ; Fistula ; Humans ; Hypospadias ; Male ; Necrosis ; Penis ; Skin ; Urethral Obstruction ; Urethral Stricture

OBJECTIVE: It has been suggested that the occurrence of persistent pain signal during the early postnatal period may alter an individual's response to pain later in life. The aim of this study is to assess whether neonatal nerve injury resulted in long-lasting consequences on nociceptive system in the rat. METHODS: We examined whether neuropathic pain behaviors and the changes of spinal neuropeptides (SP, CGRP, VIP and VIP) induced by peripheral nerve injury within 1 day after birth (Neonate group) were different from those at 8 weeks after birth (Mature group). RESULTS: The Neonate group showed more robust and long-lasting pain behaviors than the Mature group. Immunohistochemical findings demonstrated that spinal SP- & CGRP-immunoreactivities(ir) of the ipsilateral to the contralateral side increased in the Neonate group, whereas those decreased in the Mature group. In addition, increase in spinal VIP- & NPY-ir of the ipsilateral to the contralateral side was more robust in the Mature group than in the Neonate group. CONCLUSION: These results suggest that peripheral nerve injury in the early postnatal period may result in long-lasting and potentially detrimental alterations in nociceptive pathways.
Animals ; Humans ; Hyperalgesia ; Infant, Newborn ; Neuralgia* ; Neuropeptides* ; Parturition ; Peripheral Nerve Injuries* ; Peripheral Nerves* ; Rats*

OBJECTIVE: To determine whether the outcomes of percutaneous epidural neuroplasty (PEN) are influenced by the type of lumbar disc herniation (LDH) and evaluate the effectiveness of PEN in patients with single-level LDH.METHODS: This study included 430 consecutive patients with single-level LDH who underwent PEN. Before treatment, the LDH type was categorized as bulging, protrusion, extrusion, and sequestration, while Pfirrmann grades were assigned according to imaging findings. Visual analog scale (VAS) scores for back and leg pain and success rates (Odom’s criteria) were assessed at 1, 3, 6, and 12 months after treatment.RESULTS: The mean preoperative VAS scores for back and leg pain were 6.90 and 4.23, respectively; these decreased after PEN as follows : 2.25 and 1.45, respectively, at 1 month; 2.61 and 1.68, respectively, at 3 months; 2.28 and 1.48, respectively, at 6 months; and 2.88 and 1.48, respectively, at 12 months (p<0.001). The decrease in VAS scores for leg pain was significantly greater in the extrusion and sequestration groups than in the other two groups (p<0.05); there were no other significant differences among groups. More than 70% patients exhibited good or excellent 12-month outcomes according to Odom’s criteria. Subsequent surgery was required for 59 patients (13.7%), with a significantly higher rate in the extrusion (25.0%) and sequestration (30.0%) groups than in the bulging (7.3%) and protrusion (13.8%) groups (p<0.05). Nevertheless, subsequent surgery was not required for >70% patients with extrusion or sequestration. Patients with Pfirrmann grades 1–3 (14.0–21.5%) showed a significantly higher rate of subsequent surgery than those with Pfirrmann grade 0 (4.9%; p<0.05).CONCLUSION: Our findings suggest that PEN is an effective treatment for back and leg pain caused by single-level LDH, with the outcomes remaining unaffected by the LDH type.
Follow-Up Studies ; Humans ; Intervertebral Disc Displacement ; Leg ; Low Back Pain ; Treatment Outcome ; Visual Analog Scale

OBJECTIVE: The central venous pressure(CVP) could affect the vertebral venous pressure, which in turn may influence blood loss during lumbar spinal surgery. The authors perform prospective clinical study to investigate the influence of the CVP on the amount of intra-operative blood loss and operating time. METHODS: Total 134 patients having various degenerative lumbar spinal pathology were treated by laminectomy and spinal fusion using posterior lumbar interbody fusion with cages and pedicle screws. The CVP was measured after prone positioning in all the patients. The correlation between the CVP and intra-operative blood loss and operating time were analyzed. RESULTS: The mean CVP after prone positioning was 10 cmH2O(5-18). The mean amount of intra-operative blood loss and operating time were 1884 cc and 213 minutes, respectively. The amount of blood loss and operating time significantly increased with the extent of spinal fusion. The CVP was significantly correlated with intra-operative blood loss and operating time(p<0.05). CONCLUSION: With increased CVP on prone position, there is a tendency of increasing amount of blood loss and operating time. The measurement of CVP is useful in determining the position providing a bloodless field during spinal fusion.
Central Venous Pressure* ; Humans ; Laminectomy ; Pathology ; Prone Position* ; Prospective Studies ; Spinal Fusion* ; Venous Pressure

Multiple spondylolytic spondylolisthesis is very uncommon, and surgical reports are also scarce. This study describes the clinical characteristics, radiologic findings and surgical methods in 18 cases of multiple spondylolytic spondylolisthesis encountered by the authors between January, 1993 and December, 1996. Two hundred and thirty spondylolytic spondylolisthesis patients underwent surgery at this hospital during the same period, and in 18 of these, the spondylolysis was multiple, an incidence of 7.8%. There were 16 cases of two level spondylolyses, 15 of which were at L4+L5, and one case at the L3+L4 level, as well as two cases of three level spondylolyses, one at L2+L3+L4 and the other at the L3+L4+L5 level. All 18 cases showed spondylolisthesis at L4/5 and two showed two-level spondylolisthesis at L4/5 and L5/S1. A decompressive laminectomy(Gill operation) was performed in all cases and in addition, two level 360degreesfixation with pedicle screws and PLIF with cages was applied in 16 cases, and two level PLIF with cages in the other two. All showed good post-operative results. In conclusion, the condition was more common in females and bilateral L4 and L5 pars interarticularis defect and L4/5 spondylolisthesis were more common. Decompressive laminectomy(Gill operation) and two level 360degreesfixation with pedicle screws and PLIF with cages was found to be an effective operative choice.
Female ; Humans ; Incidence ; Spondylolisthesis* ; Spondylolysis

OBJECTIVES: The seroprevalence of hepatitis E virus (HEV) among high-risk groups overseas is high, but studies in these groups are rare in South Korea. We conducted the present study from April to November 2012 to obtain data on the seroprevalence and associated risk factors for HEV among slaughterhouse workers in South Korea. METHODS: Slaughterhouse workers from 80 workplaces nationwide were surveyed in South Korea in 2012. The subjects comprised 1848 cases: 1434 slaughter workers and 414 residual products handlers. By visiting 80 slaughterhouses, which were mixed with 75 of which also performed residual products handling, we conducted a questionnaire survey for risk factors and obtained blood samples in order to determine the seropositivity and seroprevalence of HEV. Anti-HEV IgG and IgM were measured using HEV IgG and IgM enzyme-linked immunospecific assay kits and HEV antigen was measured by reverse transcription polymerase chain reaction (RT-PCR). RESULTS: The seropositivity of anti-HEV IgG was 33.5% (slaughter workers 32.8% and residual products handlers 36.2%), and among the seropositive individuals the seroprevalence of anti-HEV IgM was 0.5% (slaughter workers 0.5%, residual products handlers 0.7%). The response rate of HEV-antigen as measured by RT-PCR was 0.2%. Risk factors significantly related to anti-HEV IgG seropositivity were age, sex , and working duration (slaughter workers only). CONCLUSIONS: There were significant risk factors (sex, age, and working duration) for HEV identified in our study. All three positive cases for HEV-antigen by RT-PCR were related to pig slaughter but without statistical significance. To prevent HEV, an educational program and working guidelines may be needed for high risk groups.
Abattoirs ; Adult ; Aged ; Enzyme-Linked Immunosorbent Assay ; Female ; Hepatitis Antibodies/blood ; Hepatitis E/*diagnosis/epidemiology/virology ; Hepatitis E virus/genetics/*immunology/metabolism ; Humans ; Immunoglobulin G/blood ; Immunoglobulin M/blood ; Male ; Middle Aged ; Multivariate Analysis ; Prevalence ; Republic of Korea/epidemiology ; Reverse Transcriptase Polymerase Chain Reaction ; Risk Factors ; Workplace

OBJECTIVE: We experienced some cases of adjacent segment degeneration after spinal fusion and treated them by various reoperation methods. The authors report an evaluation of causes of adjacent segment degeneration after spinal fusion and treatment methods. METHODS: Sixteen patients was admitted to our hospital due to adjacent segment degeneration after spinal fusion from November 1997 to May 2001 and we operated 11 patients among 16 patients with various surgical methods. We analyzed clinical diagnosea, surgical methods, and disc degeneration status of adjacent segment following spinal fusion on 1st operation and 2nd operation, and also evaluated the clinical symptoms, type of adjacent segment degeneration, and time interval between the 1st operation and the 2nd operation. RESULTS: Clinical diagnoses on 1st operation were degenerative spondylolisthesis of four cases, chronic degenerative disc disease with spinal stenosis of six cases, and recurred herniated lumbar disc disease of one case. We treated eight cases by posterior lumbar interbody fusion, one case by 360degrees fusion, and two cases by pedicle screw fixation only. Disc degeneration on adjacent segment to spinal fusion existed already in nine among 11 patients before spinal fusion. Types of adjacent segment degeneration after spinal fusion were disc degeneration of two cases, lumbar instability of three cases, lumbar stenosis of four cases, and lumbar instability and stenosis of two cases. Most patients complained of low back pain due to disc degeneration and instability, and some patients complained of leg and buttock pain due to stenosis. Time interval from 1st operation to reoperation was 20 months through 99 months, mean time interval was 57 months. CONCLUSION: Inevitable compensatory mechanism occurs at adjacent segment after fusion, because of stress concentration and alteration of biomechanics after fusion. But, we achieve excellent or good results of reoperation surgical treatment for adjacent segment degeneration after spinal fusion.
Buttocks ; Constriction, Pathologic ; Diagnosis ; Humans ; Intervertebral Disc Degeneration ; Leg ; Low Back Pain ; Reoperation ; Spinal Fusion* ; Spinal Stenosis ; Spondylolisthesis