No abstract available.
Humans ; Risk Factors*

Cervicogenic headache (CGH) is not universally accepted as terminology used to discuss headaches associated with disorders of the cervical spine. Sjaastad was the first to describe CGH that its definition and diagnosis relied entirely on clinical features. Pain is often triggered by irritation of nociceptors from structures in the cervical spine, and so diagnostic criteria of CGH have been established with agreement that these headaches start in the neck or occipital region and are associated with tenderness of cervical paraspinal tissues. Past history and clinical features are important to detect and diagnose the disease because the significance of radiological findings and advanced diagnostic testing is unclear. Gunn's intramuscular stimulation (IMS) is a treatment modality of CGH upon radiculopathic model. We tried IMS for treatment of 3 patients with CGH. After IMS, the patients were well respond the therapy and the results were satisfactory. Therefore we recommend the IMS for the treatment of CGH.
Diagnosis ; Diagnostic Tests, Routine ; Headache ; Humans ; Neck ; Nociceptors ; Post-Traumatic Headache* ; Spine

Purpose: This study was conducted to understand the meaning of the work performance of infection control nurses (ICNs) in general hospitals during the early COVID-19 pandemic. Methods: This was a qualitative study to explore and describe the implications of the work performance of ICNs during the early COVID-19 pandemic through a phenomenological approach. One-on-one in-depth interviews were conducted with ICNs who had been working since before the COVID-19 pandemic in the infection control department. Results: The topics brought up by the participants were categorized into five themes. The themes included “confusion caused by the early COVID-19 pandemic,” “exhaustion due to an explosion of work related to COVID-19,” “active response as an ICN,” “emphasis on the importance of infection control,” and “overcoming the early COVID-19 pandemic”. Conclusion It is necessary to strengthen the competence of ICNs as experts and establish a career management system to overcome the confusion and physical and psychological difficulties experienced by ICNs.

No abstract available.
Humans

We have analyzed two (BclI and XbaI) intragenic restriction fragment length polymorphisms (RFLPs) and St14 (DXS52) variable number of tandem repeats (VNTR) by rapid PCR method in 97 unrelated normal subjects. The incidences for positive Bc1I and XbaI polymorphic sites in the Koreans were 81% and 72%, respectively, which were higher than other ethnic groups but similar to that reported in the Chinese or Japanese, giving the heterozygosity rate of 0.32 and 0.40, respectively. The amplified allele size was 880 bp with no other polymorphism in the analysis of St14 (DXS52) VNTR. This finding should be taken into account in the planning of a prenatal diagnosis program for ethnic Koreans
Base Sequence ; Gene Frequency ; Hemophilia A/epidemiology/*genetics ; *Heterozygote Detection/methods ; Human ; Korea/epidemiology ; Molecular Sequence Data ; Polymerase Chain Reaction ; Polymorphism, Restriction Fragment Length ; Prevalence

Benign neoplasms of the stomach are uncommon in children. They include adenomatous and hyperplastic polpys, leiomyomas, lipomas, and other lesions. Gastric leiomyoma in childhood represent only 1% of all gastrointestinal neoplasms reported, and slightly more than half of these are gastric. The tumor arises in the muscle layer of the stomach and is usually intragastric and submucosal. Barium contrast studies are useful in localizing leiomyoma with significant intramural or submucosal growth. An endoscopy can permit histologic confirmation if the tumor has eroded through the mucosa. Differentiation however, of malignant lesions from benign submucosal leiomyomas may be difficult. Using endoscopic ultrasonund imaging, highly accurate gastrointestinal tumor characterization, especially submucosal masses, and differentiation of malignant from benign lesion are now relatively possible without surgery. We experienced a case of a gastric submucosal tumor regarded as a leiomyoma, which was diagnosed using endoscopic ultrasonography, and report the findings with a review of related literatures.
Barium ; Child* ; Cytochrome P-450 CYP1A1 ; Endoscopy ; Endosonography* ; Gastrointestinal Neoplasms ; Humans ; Leiomyoma ; Lipoma ; Mucous Membrane ; Stomach

PURPOSE: Epidormoid cysts are benign epithelial cysts often ocurring within the skin of face and trunk. But carcinomatous change is rare. The authors experienced a case of squamous cell carcinoma arising from the wall of epidermoid cyst of axilla and report the radiologic and pathologic findings with a brief review of the literatures. METHODS AND MATERIALS: Plain chest radiograph, US and enhanced CT of axilla were takened. We analyzed radiologic findings of squamous cell carcinoma in the wall of epidermoid cyst of axilla and correlated with pathologic findings. RESULTS: Plain chest radiograph revealed a huge axiilary mass without bony destruction or calcification. showed a heterogenous hyperechoic mass with eccentrical cystic lesion. Outer margin of the mass was irregular. No posterior acoustic enhancement was seen. Postcontrast CT scan showed a circumscribed complex mass with irregular enhancing rim. During operation mass was located within subcutaneous layer and internal contents of the mass were brown, necrotic keratinous debries. CONCLUSION: Differentiation from solid tumor was difficult. But intradermal or subcutaneous location and rapid growing were characteristic.
Acoustics ; Axilla* ; Carcinoma, Squamous Cell* ; Epidermal Cyst* ; Radiography, Thoracic ; Skin ; Tomography, X-Ray Computed

Carcinoma of lung is classified by histologic cell type, this is based on predominant major cell population by tissue specimen. But in fact a range of 13% to 63% of lung cancer has been appeared to be heterogeneous cell type at the light microscopic level. After treatment of the mixed lung cancer and/or with time there are reports that cell type is changed. Because it is possible that the tumor were pleomorphic and that the antitumor therapy eliminated the more sensitive cell population and permitted the subsequent emergence of the more resistant cell population. The authors reported here, a case of 32 year old female patient with mixed lung cancer composed of three cell type, and this is the first case in Korea.
Adult ; Female ; Humans ; Korea ; Lung ; Lung Neoplasms ; Population Characteristics

BACKGROUND: The hepatocyte growth factor (HGF) is a cytokine modulating epithelial cell proliferation and motility. A circulating HGF level is frequently increased in a variety of tumors including advanced breast cancer. The clinical usefulness of measuring circulating HGF in breast cancerwas evaluated in this study. MATERIALS AND METHODS: The plasma HGF levels in patients with primary (n=58) and recurrent breast cancer (n=13) were measured by the ELISA method using Quantikine (R&D, Minneapolis, MN, USA) kit. The results were compared with those of age-matched healthy controls (n=53). The mean (+/-SD) levels of HGF were also compared between primary and recurrent breast cancerpatients. The correlation of the circulating HGF level and the conventional prognostic factors such as tumor size, lymph node involvement, Her-2/neu over-expression, DNA aneuploidy was studied to evaluate the clinical usefulness of HGF as a new prognostic indicator in breast cancer. RESULTS: Plasma HGF levels (mean+/-SD) increased in breast cancer patients (788+/-853 pg/mL), compared with those of age-matched healthy control women (426+/-120 pg/mL) (P<0.05). Patients with recurrent breast cancer (1, 945+/-1, 544 pg/mL) showed increased HGF levels compared with primary breast cancer (592+/-132 pg/mL) (P<0.001). No significant correlations between plasmaHGF levels and conventional prognostic indicators of breast cancer including tumor size, lymphnode involvement, Her-2/neu over-expression, DNA aneuploidy, and histologic grade were found. CONCLUSIONS: The above findings suggest that the measurement of plasma HGF levels in breast cancer patients may be useful for early detection of recurrence.
Aneuploidy ; Breast ; Breast Neoplasms* ; DNA ; Enzyme-Linked Immunosorbent Assay ; Epithelial Cells ; Female ; Hepatocyte Growth Factor* ; Humans ; Lymph Nodes ; Plasma ; Recurrence

Recent advances in techniques and strategies use to detect cancer in its early stages and to treat it effectively has the survival rate of cancer patients and the number of long-term cancer survivors continually increasing. Unfortunately, many cancer survivors are at risk for various late and long-term effects of cancer treatments including the radiotherapy. Long-term cancer survivors can be also seen for a hospice and palliative care because of cancer recurrence and they are at risk of delayed reactions to radiotherapy. So, the understanding and knowledge of radiation reactions is required for the proper medical diagnosis, management, and coordination of the potential reactions that may occur in these care setting. In effort to increase the survival rate in cancer patients and to decrease the adverse effects of cancer treatment, many clinical studies have been and continue to be conducted. The efforts of these studies have thus resulted in the advancement of cancer treatments. Regrettably, the overall interest in how to manage adverse effects of cancer treatment such as radiotherapy appears seemingly low in clinical practice and its advanced studies as a whole are delayed and deficient. It is imperative that the medical community show an enthusiastic interest in the aftercare of cancer patients and cancer survivors in order to create a complementary integrative approach that will eliminate radiotherapy related pain/discomfort or illness in hospice and palliative care settings.
Aftercare ; Hospice Care ; Hospices ; Humans ; Palliative Care ; Recurrence ; Survival Rate ; Survivors