1.Arthroscopic Resection of the Acromioclavicular Joint.
Yong Girl RHEE ; Young Kyu KIM ; Young Soo CHUN
The Journal of the Korean Orthopaedic Association 1998;33(5):1233-1239
Acromioclavicular joint pain is a common cause of shoulder-related symptoms. Frequently, nonoperative treatment regimens resolve symptoms originating from acromioclavicular joint. However, patients refractory to conservative therapy require operative intervention and the resection of distal end of the clavicle has proven to be a reliable method in these patients. We performed fourteen cases of arthroscopic distal clavicle resection for acromioclavicular joint lesions between February 1995 and February 1997 and reviewed the efficacy of the arthroscopic distal clavicle resection, retrospectively. Causes of acromioclavicular joint pathology were 7 cases of degenerative osteoarthritis, 6 traumatic osteoarthritis and 1 partial instability. Average patient age was 50 years (range 19 to 70 years). Preoperatively all patients had pain, whereas 57% had acromioclavicular tenderness and 86% positive adduction test. The operations were performed with subacromial bursal approach. The average length of distal clavicle resection was 10mm (range 5 to 18mm). At an average follow-up of 18 months (range 8 to 30 months), the ASES score ranked 6 shoulders in excellent (43%), 6 good (43%), 1 fair (7%), and 1 poor (7%). Thus, the overall results suggest that arthroscopic acromioclavicular resection is one of the effective methods for the treatment of acromioclavicular joint pathology.
Acromioclavicular Joint*
;
Clavicle
;
Follow-Up Studies
;
Humans
;
Osteoarthritis
;
Pathology
;
Retrospective Studies
;
Shoulder
2.Arthroscopic Fixation for Unstable SLAP Lesion Using Biodegradable Tack.
Yong Girl RHEE ; Young Kyu KIM ; Young Soo CHUN
The Journal of the Korean Orthopaedic Association 1998;33(3):508-514
Twenty six consecutive patients with superior labrum anterior to posterior (SLAP) lesions of the shoulder involving the hiceps attachment to the labrum were fixed with biodegradable tack through a new lateral portal arthroscopically and reviewed to evaluate the efficacy of the biodegradable tack tixation in the unstable SLAP lesion. The tack was placed at the posterosuperior aspect of biceps attachment and directed toward anteroinferior via lateral portal just lateral to the acromial margin. Mean follow up duration was 18 months (range, 8 to 27). According to Snyder s classification, 24 cases were type ll, 1 case was type III and 1 case was type IV. lsolated SLAP lesion was nine cases (35%,) in our series. Thirteen cases were associated with the unidirectional anterior instability, one case with the multidirectional instability, 2 cases with the full thickness tear of the rotator cuff and 1 case with the acromioclavicular injury. Preoperative scores increased postoperatively by using the American Shoulder and Elbow Society (ASES) evalualion system in all cases. ln isolated SLAP lesions, pain scores improved from 3.0 to 4.2, stability scores from 3.7 to 5.0, and function scores from 2.7 to 3.4. In associated SLAP lesions, pain scores improved from 3.2 to 4.2, stability scores from 3.5 to 4.8 and function scores from 3.1 to 3.9, Overall scores improved from 71 to 93 in associated SLAP lesions and improved from 67 to 90 in isolated lesions. Eiehteen patients(69%) achieved excellent results and 6 patients(23% ) ohtained good results. And there were no complications related to the use of biodegradable implant. Thus, arthroscopic fixation is recommendable in the management of the unstable SLAP lesions.
Absorbable Implants
;
Classification
;
Elbow
;
Follow-Up Studies
;
Humans
;
Rotator Cuff
;
Shoulder
3.Restoration of Hormone Dependency in Estrogen Receptor - Lipofected MDA-MB-231 Human Breast Cancer Cells.
Young Jin SUH ; Jae Hee CHANG ; Chung Soo CHUN
Journal of the Korean Cancer Association 1999;31(3):473-482
PURPOSE: The loss of estrogen and progesterone receptors appeats to be associated with a progression to less differentiated and hormone-independent tumors. The gain of hormone independency over time even in estrogen receptor-positive tumors has become another obstacle to endocrine therapy for breast cancer. We tried to regain the hormone dependency in estrogen receptor-negative breast cancer cells by lipofecting estmgen receptor cDNA. MATERIALS AND METHODS: The mutant human estrogen receptor cDNA (pSGS-HEO) was lipofected into estrogen receptor-negative human breast cancer cell line MDA-MB-231, in an attempt to restore their sensitivity to antiestrogen. Then the effects of 17p-estradiol and tamoxifen were studied by counting viable cell numbers after treating the lipofected cell line with either one or together. RESULTS: Culture medium cantaining phenol red, a weak estrogen, has growth advantages compared with culture medium without it. In both culture conditions, cell growth was most profoundly inhibited in 4 days after lipofection with mutant human estrogen receptor cDNA, which was overcome after that day. Tamoxifen, as an antiestrogen, showed a growth inhibitory effect slightly stronger tban combined conditions of tamoxifen and 17- estradiol compared to estrogen-treated group and to control, and the inhibitory effect was lasted 4 days. CONCLUSION: The temporary induction of estrogen receptor by lipofection with pSGS-HEO on estrogen receptor-negative human breast cancer cell line MDA-MB-231 showed negative growth control on these cells by tamoxifen, indicating that liposome-mediated estrogen receptor transfection may be used as a novel therapeutic strategy for hormane independent human breast cancers in the near future.
Breast Neoplasms*
;
Breast*
;
Cell Count
;
Cell Line
;
DNA, Complementary
;
Estradiol
;
Estrogen Receptor Modulators
;
Estrogens*
;
Genetic Therapy
;
Humans*
;
Phenolsulfonphthalein
;
Receptors, Progesterone
;
Tamoxifen
;
Transfection
4.Papillary Eccrine Adenoma.
Young Gee KIM ; Kwang Gil LEE ; Soo Il CHUN
Korean Journal of Dermatology 1990;28(1):107-111
We report a case of papillary eccrine adenoma occurring in a 39-year-old male who had a walnut sized, firm nodule on the right knee without subjective symptoms. Histopathologic exammination revealed a well circumscribed, non-capsulated dermal nodule consisting of multiple ducts with various sizes. These ducts were composed of double layered epithelial cells in most areas, but in some areas severe intraluminal papillation snd pseudostratification into the lumen were seen and the lumina were filled with a homogenous eosinophilic substance and partially with calcium deposition. Immunohistochemical studies with S-100 antigen and csrcinoembryonic sntigen (CEA) were also performed. Positivity for these sntigens strongly supports the hypothesis that this unusual neoplasm differentiates toward the eccrine secretory coil.
Adenoma*
;
Adult
;
Calcium
;
Eosinophils
;
Epithelial Cells
;
Humans
;
Juglans
;
Knee
;
Male
5.A Case of Eosinophilic Pustular Folliculitis.
Soo Il CHUN ; Won hyoung KANG ; Young Jin KOH
Korean Journal of Dermatology 1984;22(6):689-694
We report herein a case of eosinophilic pustular follicultis in a 20-year-old man. The patient showed typical clinical picture with specific laboratory and histopathological findings of eosinophilic pustular folliculitis. The patient responded well to systemic administration of corticosteroid and dapsone.
Dapsone
;
Eosinophils*
;
Folliculitis*
;
Humans
;
Young Adult
6.A Case of Giant Cell Tumer of Tendon Sheath Associated with Regional Bone Destruction
Young Soo BYUN ; Hong Kun LEE ; Chun Bang BUN
The Journal of the Korean Orthopaedic Association 1976;11(2):237-241
An giant cell tumor arising from the tendon sheath and other soft tissue of the extremities, hasbeen of clinical and pathologic interst for many years, which is the second most common tumor of the hand, but it is not common in other location. One case of tendon sheath giant cell tumor with regional bone destruction on the pharangeal bone is presented which experienced at Department of Orthopaedic Surgery, Korea University recently. At first, the lesion of bone that is confused with Enchondroma in roentgenographically, which is confirned regional bone destruction of tendon sheath giant cell tumor by histologically. The tumor is composed of a vascularized network of spindle shaped or ovoid stromal cell regularly and rather interspersed with multinuclear cell and xanthoma cells. We report a case of giant cell tumor of tendon sheath and review of literature.
Chondroma
;
Extremities
;
Giant Cell Tumors
;
Giant Cells
;
Hand
;
Korea
;
Stromal Cells
;
Tendons
;
Xanthomatosis
7.The application of the Halo-pelvic apparatus in Quadriplegia with Unstable fracture-dislocation of cervical spine
Young Soo BYUN ; Hong Kun LEE ; Chun Bang BUN
The Journal of the Korean Orthopaedic Association 1976;11(3):392-396
The head-pelvic skeletal traction was first attempted in 1958 by Arther R. Hodgson., and was described. The Halo skull traction apparatus by Perry and Nickel (1959), the method were provided for immobilising the unstable cervical spine, correction of the Scoliotic deformity, Tuberculotic Kyphosis, and other deformed disease. We performed Halo-pelvic apparatus,after posterior-fusion of unstable cervical spine, on a 24 year old male, with Quadriplesia due to Fracture-dislocation of the 7th cervical spine in May 1976. The following were the condition to be met: 1) Rigid stabilization and improved the cervical pain. 2) progressive adjustable., longitudinal traction for reduction 3) The patient was able to sitting position withont other Supports. 4) No pressure sores developed as happens beneath a cast. 5) Ease of patient management and taking of Roentogenogram.
Congenital Abnormalities
;
Humans
;
Kyphosis
;
Male
;
Methods
;
Neck Pain
;
Nickel
;
Pressure Ulcer
;
Quadriplegia
;
Skull
;
Spine
;
Traction
8.A case of angiolymphoid hyperplasia with eosinophilia and its treatment with carbon dioxide laser.
Soo Gyoung HUR ; Chun Sang KIM ; Seung Churl LEE ; Inn Ki CHUN ; Young Pio KIM
Korean Journal of Dermatology 1991;29(2):130-135
A 45-year-old female noticed a pruritic erythematous firm pea sized nodule on the left earlobe about 18 years prior to uisiting our clinic. The lesion has increased in size gradually and involved the whole earlobe. On March 1988, the earlobe became enlarged with extreme pruritus, and showed a tendency of easy bleeding by scratch. The skin lesions consisted of multiple pea to bean sized, shiny dusky red colored, moderate firm nodules or tumors with edema on the left. ear helix, antehelix, external auditoy meatus, and retroauricular fold. The histopathologic studies revealed vascular proliferation, presence of histiocyt.oid endothelial cells, and prominent inflammatory infiltration including large numtaer of eosinophils with fibrosis in the dermis. Hematological studies revealed eosinophilia(9%). Excision of several nodules and intralesional injection of trinmcinolon acetonide did not show complete favorable effect and treatment with carbon dioxide laser was attempted. With the patient under local anesthesia with 2% lidocaine, the lesion were treated with three t,o four passes at 25,100 second intervals with ieradiance 5W(cm. The pro- cedure was repeated until no abnormal findings could be seen in the treatment zone. Treatment with carbon dioxide Iaser on the patient obtained a satisfactory result.
Anesthesia, Local
;
Angiolymphoid Hyperplasia with Eosinophilia*
;
Bezafibrate
;
Carbon Dioxide*
;
Carbon*
;
Dermis
;
Ear
;
Edema
;
Endothelial Cells
;
Eosinophils
;
Female
;
Fibrosis
;
Hemorrhage
;
Humans
;
Injections, Intralesional
;
Lasers, Gas*
;
Lidocaine
;
Middle Aged
;
Peas
;
Pruritus
;
Skin
9.Calcifying odontogenic cyst associated with odontoma.
Jae Hwy LEE ; Jung Soo BAE ; Dong Soo JANG ; Jin KIM ; Young Chan CHUN
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1993;19(2):235-244
No abstract available.
Odontogenic Cyst, Calcifying*
;
Odontoma*
10.Calcifying odontogenic cyst associated with odontoma.
Jae Hwy LEE ; Jung Soo BAE ; Dong Soo JANG ; Jin KIM ; Young Chan CHUN
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1993;19(2):235-244
No abstract available.
Odontogenic Cyst, Calcifying*
;
Odontoma*