A case of Peutz-Zeghers syndrome in a year and 8 month old girl was Presented. Her chief complaints were abdominal pain, vomiting and melanin pigmemtation on the lips and perioral area. On family history, her mother and elder sister suffered from same symptom. Physical examination showed melanin pigentation on the lips and perioral area, and markedly distended abdomen. Abdominal simple X-ray film showed fluid level, and so diagnosed as small bowel obstruction. Operation performed at 2nd admission day, and those findings were intusussusception of jejunojejunal type and multiple polyps. The diagnosis was confirmed by family history, characterisic pogmentation and multiple small intestinal polyps of jejunum. Brief review of related literatures were also presented.
Abdomen ; Abdominal Pain ; Diagnosis ; Female ; Humans ; Infant ; Intestinal Polyps ; Jejunum ; Lip ; Melanins ; Mothers ; Physical Examination ; Polyps ; Siblings ; Vomiting ; X-Ray Film

Congenital lung cyst is known to be very rare. Recently we experienced one case of congenital lung cyst wihich was confirmed by autopsy. Review of literature was done briefly.
Autopsy ; Lung*

Seventy four children with mumps meningitis were hospitalized to Pediatric department, Hangyang University Hospital between May, and August, 1977. The clinical illness of these children were studied and the following results were obtained. 1. The incidental ratio to total inpatients was 1%. 2. The seasonal distribution was highest in summer, and the peak incidence in July(28%). 3. The sex incidence was more common in male(M:F=4:1). 4. According to age distribution, Children between 6 to and 8 years of age comprised 45.2% of alll studied cases. 5. The signs and symptoms of mumps meningitis on admission revealed vomiting, fever, neck stiffness, positive Kernig's sign etc. in order. 6. The symptoms and signs of meningitis were present in 5(7%) before salivary gland swelling, in 56(75%) after it, and in 13(18%) simultaneously. 7. Other salivary gland involvement without parotid gland swelling was relatively high in mumps meningitis compared with simple mumps. 8. Fever was normalized within 4th hospital day in 85% of cases. 9. On C.S.F. findings, the cell counts were elevated in all cases, protein was normal or slightly elevated and sugar was normal in all cases. 10. Average hospital days were 4 days. 11. All cases were completely recovered within 7th hospital day except a case of orchitis and a case of pancreatitis.
Age Distribution ; Cell Count ; Child ; Fever ; Humans ; Incidence ; Inpatients ; Male ; Meningitis ; Mumps* ; Neck ; Orchitis ; Pancreatitis ; Parotid Gland ; Salivary Glands ; Seasons ; Vomiting

We report three cases of Diabetes insipidus which charactrized by the polyuria and polydipsia. All of the three cases well controlled with oral addministration of chlorpropamide. Two cases were idiopathic and the other was suspected pituitary tumor. A briet review of literature was made.
Chlorpropamide ; Diabetes Insipidus* ; Pituitary Neoplasms ; Polydipsia ; Polyuria

3 cases of congenital leukemia, 27 day old female, 1 month old and 6 month old male were presented. We made diagnosis by clinical features as well as peripheral blood and bone marrow studies and autopsy findings. Two of three revealed acute Lymphocytic leukemia and one case revealed acute myelomonocytic leukemia on peripheral blood smear and bone marrow studies.
Autopsy ; Bone Marrow ; Diagnosis ; Female ; Humans ; Infant ; Infant, Newborn ; Leukemia* ; Leukemia, Myelomonocytic, Acute ; Male ; Precursor Cell Lymphoblastic Leukemia-Lymphoma

A study on physically and mentally handicaped children was carried out by health commttee of korean pediatric Association on August, 1977. 654 children in 5 special children's Institutes in Seoul area were observed and the results obtained were as follows ; 1. 393 out of 654 cases were males and male to female ratio was 6 : 4. The most Common age group in institutes were over 10 years (45.6%). As the age goes young, the number of cases were decreased. 2. 43.7% of all cases were orphans. 3. The most common handicap was cerebral palsy(33.3%). Poliomyelitis(24.0%) and mental retardation (20.0%) were the next and these 3 handicaps were ranged 78.1% of all handicaps. The other less common handicaps were Cong. Anomaly(8.1%), mongolism(4.3%) Tb spine or hip joint(2.1%) and microcephaly(2.0%) in order of frequency. 4. Handicaps originated from acquired and congenital were 37.5% and 15.9% respectively. But the remains were obscure in origin. Cong. Anomaly, mongolism and microcephaly were common causes of congenital origin and poliomyelitis, cerebral palsy and Tb hip or spine were frequently acquired. 5. Only 64 cases(18.0%) of cerebral palsy and mental retardation had Known Causes. These were caused by birth injury(24cases), prematurity, Kern icterus or meningigis. 6. 65.4% of all cases had mentally retardation. 87.2% of cerebral palsy nd 83.0% of congenital anomaly were mentally retarded and all cases with mongolism, microcephaly, hydrocephalus and spina bifida mental retardation. 7. The most common site of congenital anomaly was extremities or joints(47.1%) and multiple anomalies were 28.5% of all anomalies. 8. Less than 6 months of institution were common in paid cases(24.9%) in spite of 5~10 year in institule were common in orphans (28.3%). Even in paid cases, economic stase were very low level.
Academies and Institutes ; Cerebral Palsy ; Child* ; Child, Orphaned ; Down Syndrome ; Extremities ; Female ; Hip ; Humans ; Hydrocephalus ; Intellectual Disability ; Jaundice ; Male ; Mentally Disabled Persons ; Microcephaly ; Parturition ; Poliomyelitis ; Seoul ; Spinal Dysraphism ; Spine ; Statistics as Topic*

A statistical study on visually handicapped children was performed by The Committee on Health of Korean Pediatric Association from July to October, 1978. 3,930 boys and girls in middle school children(3rd grade; around 15 years of age) were studied and the results were obtained as follows; 1, 788 out of 3,930 children(20.1%) were visually handicapped. There were no sex preponderance. 2. Annual incidence of visual handicap was 2.2% of all children studied. 3. There were no specific age preferance for handicapping and annual incidence of visual retardations among the handicapped children was 13.7%(10~19%). 4. Children wearing corrective glasses were 62.8% of all handicapped children and 69.8% of them were began to wear the glasses after entrance of middle school. 5. Nearly all of the handicapped children were suffered from symptoms related with visual defect and the most common difficulty was learning problems(67.5%). Headache(6.7%) and dizziness(5.5%) were another difficulties. 6. 92.5% of children wearing glasses were improved their symptoms related with poor visions but 79.8% of children wearing glasses were suffered form discomfortness by glasses itself. 7. The reasons wearing no glasses among the visual handicaps were advices by parents and friends due to bad effects of glasses on beauty(321.%), hesitation(30.7%) and shyness(13.3%). 8. High famillial incidence of visual handicaps were noted in visually handicapped children than with normal vision. 9. There were no difference between the children with defective vision and normal children on number of television sets at home, places of telvision set ups(children's room or parent?sroom), hours watching televison per day, presence or absence of children's study rooms and reading postures. 10. Habits of watching television or reading books from too short distance, improper illumination when they read the books at home were much more freqently observed in children with visual handicap than children with no defect.
Child ; Disabled Children* ; Disabled Persons* ; Eyeglasses ; Female ; Friends ; Glass ; Humans ; Incidence ; Learning ; Lighting ; Parents ; Posture ; Statistics as Topic* ; Television

PURPOSE: The prevalence and clinical outcomes of asymptomatic carotid artery stenosis (CAS) in patients with coronary artery disease (CAD) have not been thoroughly studied. We examined the prevalence and predictors of asymptomatic CAS detected by carotid angiography and determined the impact of concomitant CAS on prognosis in patients undergoing coronary angiography (CAG) due to CAD. MATERIALS AND METHODS: Between January 2013 and July 2015, 395 patients who underwent carotid digital subtraction angiography to screen for CAS during CAG were analyzed. The presence of CAS was defined as angiographically significant stenosis (≥50%). Major adverse cardiac and cerebrovascular event (MACCE) rates were compared between patients with and without CAS. MACCEs included a composite of cardiac death, cerebrovascular death, acute myocardial infarction, and stroke. RESULTS: Of the 395 patients, 101 (25.5%) patients had significant CAS. The independent predictors of CAS were age, male sex, hypertension, diabetes, and multi-vessel disease. In patients with CAD, the presence of CAS was as an independent predictor for MACCEs after adjusting for confounding factors (hazard ratio 2.47, 95% confidence interval 1.16–5.24, p=0.018). CONCLUSION: Asymptomatic CAS was documented in up to 25% of patients with CAD. The presence of CAS in patients with CAD was associated with a higher rate of MACCEs. Therefore, detection of CAS by carotid angiography during CAG may be important for risk stratification for CAD patients, particularly those with multi-vessel disease.
Angiography ; Angiography, Digital Subtraction ; Carotid Arteries ; Carotid Stenosis ; Constriction, Pathologic ; Coronary Angiography ; Coronary Artery Disease ; Death ; Humans ; Hypertension ; Male ; Myocardial Infarction ; Prevalence ; Prognosis ; Stroke

BACKGROUND/AIMS: The purpose of this study was to evaluate the diagnostic usefulness of PET/CT for pancreatic malignancy. METHODS: We retrospectively analyzed medical records of 115 patients with pathologically diagnosed pancreatic cancer between January 2003 to August 2008 who underwent abdominal CT and PET/CT examination before histological confirmation. CT and PET/CT images were reviewed in single-blinded status and diagnostic ability on primary pancreatic lesion, regional lymph node metastasis, and distant metastasis was evaluated. RESULTS: 99 patients (86%) had malignant diseases including 91 cases of adenocarcinoma, and 16 patients (14%) benign diseases. Only CA 19-9 value and SUV were significantly different between PET/CT positive and negative groups (p=0.001, p<0.001). Sensitivity, specificity and positive predictive values (PPV) of both modality for pancreatic lesion were same (94%, 62%, and 95%, respectively), and negative predictive values (NPV) were 67% on CT and 57% on PET/CT. PET/CT correctly diagnosed 8 cases (6.9%) of falsely diagnosed pancreatic lesion on CT. Nine cases (15.7%) of misdiagnosed lymph node metastasis on CT were correctly diagnosed on PET/CT. But, there was no significant difference in the diagnosis of regional lymph node metastasis. 3 out of 29 cases of distant metastasis, except 2 cases of supraclavicular lymph node metastasis, were additionally diagnosed by PET/CT. But, overall sensitivity of distant metastasis was significantly higher in CT (83% vs 69%, p=0.045). CONCLUSIONS: Although PET/CT provided additional correct diagnoses in many cases, it showed fair diagnostic power for primary pancreatic lesion and lymph node metastasis, and lower sensitivity for distant metastasis. Therefore, PET/CT should be used as an supplementary modality of CT in diagnosing pancreatic malignancy.
Adult ; Aged ; Aged, 80 and over ; CA-19-9 Antigen/analysis ; Diagnostic Errors ; Female ; Humans ; Lymphatic Metastasis ; Male ; Middle Aged ; Pancreatic Neoplasms/*diagnosis/pathology ; *Positron-Emission Tomography ; Retrospective Studies ; *Tomography, X-Ray Computed

BACKGROUND/AIMS: Although controversial, probiotics and dietary fiber are commonly used for patients with irritable bowel syndrome (IBS). We evaluated the effects of multistrain probiotics on the symptoms of IBS to determine whether the addition of dietary fi ber had an additive effect on constipation-predominant IBS. METHODS: A total of 142 participants who met the Rome III criteria were recruited and randomized into a control group or a test group. Participants in the control group received multistrain probiotic fermented milk with Streptococcus thermophilus, Lactobacillus acidophilus and Bifidobacterium infantis; the participants in the test group received the same probiotic fermented milk mixed with dietary fi ber such as sea tangle extracts, radish extracts and glasswort extracts. The patients were treated for four weeks. RESULTS: Most of the symptoms of IBS, with the exception of fl atulence, stool consistency, and frequency of defecation, signifi cantly improved in both groups. In the analysis of IBS subtypes, especially constipation-predominant IBS, the frequency and duration of defecation and straining at stool were improved more in the test group than in the control group. CONCLUSIONS: Dietary fiber had additive benefits for the symptoms of constipation, especially in constipation-predominant IBS.
Bifidobacterium ; Constipation ; Defecation ; Dietary Fiber ; Humans ; Irritable Bowel Syndrome ; Lactobacillus acidophilus ; Milk ; Probiotics ; Raphanus ; Rome ; Sprains and Strains ; Streptococcus thermophilus