Serum Lipoperoxide levels were studied in 50 normal Korean and in the following patients; 26 patients with diabetes mellitus, 20 patients with hypertension, 14 patients with ischemic heart disease, 8 patients with cerebrovascular accident and 6 patients with nephrotic syndrome. The results obtained are summarized as follows; 1. In normal Korean, the average serum lipoperoxide level was 2.62+/-0.27 nmoles M.D. A./ml, with no difference by the sex. 2. In the cases with various disease which in supposed to be related to abnormal lipid metabolism, that is, diabetes mellitus, hypertension, ischemic heart disease, nephrotic syndrome, the serum lipoperoxide value showed statistically significant elevation compared to that of the normal control (p<0.01), but in the patients with cerebrovascular accident the elevation was not significant (p>0.05). 3. The serum lipoperoxide level was coarsely related with the serum concentration of cholesterol and total lipid, the correlation coefficient of which were 0.34 and 0.35 respectively (p<0.05).
Cholesterol ; Diabetes Mellitus ; Humans ; Hypertension ; Lipid Metabolism ; Myocardial Ischemia ; Nephrotic Syndrome ; Stroke

Serum Lipoperoxide levels were studied in 50 normal Korean and in the following patients; 26 patients with diabetes mellitus, 20 patients with hypertension, 14 patients with ischemic heart disease, 8 patients with cerebrovascular accident and 6 patients with nephrotic syndrome. The results obtained are summarized as follows; 1. In normal Korean, the average serum lipoperoxide level was 2.62+/-0.27 nmoles M.D. A./ml, with no difference by the sex. 2. In the cases with various disease which in supposed to be related to abnormal lipid metabolism, that is, diabetes mellitus, hypertension, ischemic heart disease, nephrotic syndrome, the serum lipoperoxide value showed statistically significant elevation compared to that of the normal control (p<0.01), but in the patients with cerebrovascular accident the elevation was not significant (p>0.05). 3. The serum lipoperoxide level was coarsely related with the serum concentration of cholesterol and total lipid, the correlation coefficient of which were 0.34 and 0.35 respectively (p<0.05).
Cholesterol ; Diabetes Mellitus ; Humans ; Hypertension ; Lipid Metabolism ; Myocardial Ischemia ; Nephrotic Syndrome ; Stroke

No abstract available.
Mass Screening* ; Stomach Neoplasms* ; Stomach*

BACKGROUND: It is well known that Methicillin-resistant Staphylococcus aureus (MRSA) is hardly controllable organism among pathogens of nosocomial infection. The MRSA infection control measures have been initiated at a brand new tertiary care teaching hospital which was opened in June, 1994. However, the control measures did bring out little effect. In 1997, reenforcement of all control measures were practiced in intensive care units. The measures brought out a significant improvement in reducing the incidence of MRSA infection, subsequently the same control measures were implemented through-out the entire inpatient area. METHODS: The following control measures have been reenforced since March 1997: first, application of thorough surveillance of confirmed MRSA infected patients: second, providing cohort care: third, enforcing handwashing practices after patient contact; fourth, establishing infected patients isolation zone: fifth, tagging infected patient's bed and medical record, providing disinfectant spray for washing hands, identifying and treating carriers among patient contact staffs, separate disposal of contaminated wastes, and finally repeating education of nursing staff and family members of the patients. Each month the number of incidence in MRSA nosocomial infection were followed and the leu supervisors were notified the outcome. RESULTS: The incidence of MRSA infection started to decline soon after the initiation of the control measures, from 132% in March 1997 to 5.8% in July 1997. In 1998, the infection rate maintained close to 2-3%. There had been 467 MRSA infected cases (5.7%) out of 8,253 discharges during the study period; among them 319 cases were infected once; 40 cases twice; 15 cases three times: four cases four times and 1 case seven times. The order of preference of organs infected are lungs (56.3%), wounds(11.8%), blood (7.9%), and urinary tract (1.9%). The highest incidence of this infection was found in Medicine (34.8%) and Neurosurgery (22.8%) CONCLUSION: The implementation and reenforcement of infection control measures are key to successful control of nosocomial infection, in particular, hand washing of patient contact staffs and eradication of carriers could be the most effective measures.
Cohort Studies ; Cross Infection* ; Education ; Hand ; Hand Disinfection ; Hospitals, Teaching ; Humans ; Incidence ; Infection Control ; Inpatients ; Intensive Care Units* ; Critical Care* ; Lung ; Medical Records ; Methicillin-Resistant Staphylococcus aureus* ; Neurosurgery ; Nursing Staff ; Tertiary Healthcare ; Urinary Tract

No abstract available.
Adolescent* ; Child* ; Humans ; Periodicals* ; Suicide*

Blood utilization review has recently been used to minimize inappropriate transfusion, reduce post transfusion infections and improve the quality of transfusion practices. Ajou University Hospital is a 906 bed tertiary care teaching institution. Since March, 1995, the concurrent review of blood transfusion requests using institutional blood transfusion criteria has been initiated. To evaluate the effectiveness of the transfusion review, the units of blood components transfused per patient(total number of units of blood components transfused/total number of patients discharged) and inappropriate transfusion ratio of blood components(total number of units of blood components inappropriately transfused/total number of units of blood components transfused) were compared during the concurrent review for 9 months and pre-concurrent review for 9 months, respectively. The possible savings of blood components realized by the review were also extrapolated. The results were as follows : 1. The unit transfused per patient for pre-review and during review were 0.675 (9,080/ 13,422) and 0.654(12,123/18,546) for packed RBC(PRBC); 0.417 (5,602/ 13,422) and 0.296 (5,444/18,546) for fresh frozen plasma(FFP); 0.372(5,007/13,422) and 0.424(7,868/18,546) for platelet con-centrates(PC), respectively. 2. The inappropriate transfusion ratio of blood components for pre-review and during review were 0.039 and 0.009 for PRBC; 0.321 and 0.064 for FFP; 0.143 and 0.008 for PC, respectively. These differences were statistically significant(p=0.000). 3. The PRBC and FFP anticipated to have been saved by this review was 519 units and 2,992 units annually, respectively. 4. However, 2,621 units of PC were used additionaly during this review due to increased number of oncology patients and better hemostatic therapy practiced during the same period. In conclusion, the concurrent review of transfusion requests was very effective tool to educate residents in clinical departments the transfusion medicine and improve utilization of blood and its components.
Blood Platelets ; Blood Transfusion* ; Concurrent Review* ; Humans ; Income ; Tertiary Healthcare ; Transfusion Medicine ; Utilization Review

No abstract available.
Child* ; Encephalitis* ; Female* ; Humans

Double primary cancer is defined as the case of primary malignant tumors, which must be arise in different sites and have a different histologic appearences. The number of reported cases of double primary malignant tumors has increased in recent and the occurrence of multiple primary cancers in the same individuals is one of the interesting subjects for investigation and research in relation to the carcinogenic mechanism and/or genetic factors. We have experienced a case with double primary malignant tumors of different site origins such as stomach adenocarcinoma and rectal adenocarcinoma, which were diagnosed by biopsies with gastro and colono fiberscopy. For its great rarity, we report this case with review of literatures.
Adenocarcinoma ; Biopsy ; Rectum* ; Stomach*

No abstract available.
Animals ; Horns* ; Pregnancy*

The antihypertensive effect of carteolol hydrochloride was observed in 20 cases of essential hypertension, and following results were obtained. 1. Mean drops in systolic and diastolic blood pressure by carteolol hydrochloride were 13mmHg and 9mmHg. The results of antihypertensive therapy revealed good control in 25%, fair control in 35%, poor in 20% and failure in 20% of the cases. 2. After the administration of carteolol hydrochloride, no drop in average heart rate was observed. 3. The side effect of carteolol was mild indigestion in two cases.
Blood Pressure ; Carteolol* ; Dyspepsia ; Heart Rate ; Hypertension