1.Two Cases of Acquired Hypothyroidism with Severe Obesity, Short Stature and Cardiomegaly.
So Young KANG ; Woo Sung PARK ; Mi Jin JUNG ; Young Seok LEE ; Seok Gun PARK ; Jeesuk YU
Journal of Korean Society of Pediatric Endocrinology 2003;8(2):189-195
The clinical signs of acquired hypothyroidism are usually manifested insidiously over several months to years. The incidence increases after 6 years of age and peaks at 11 to 18 years of age. The clinical symptoms and signs are fatigue, constipation, decreased growth velocity and delayed bone age, compromised intellectual performance, obesity, myxedema, hyperlipidemia, peripheral neuropathy and delayed or precocious puberty. Two children were referred to our hospital for the evaluation of severe obesity and short stature. During the evaluation we found they also had hyperlipidemia, cardiomegaly with or without pericardial effusion. Thyroid function test revealed decreased serum thyroid hormone levels with positive anti- microsome and anti-thyroglobulin antibodies consistent with long-standing acquired hypothyroidism. After the supplement of L-thyroxine, both of them showed rapid improvement of above symptoms, except for the incomplete catch-up growth. We herein report two cases of acquired hypothyroidism with severe obesity, short stature, hyperlipidemia and cardiomegaly with review of literatures.
Antibodies
;
Cardiomegaly*
;
Child
;
Constipation
;
Fatigue
;
Humans
;
Hyperlipidemias
;
Hypothyroidism*
;
Incidence
;
Microsomes
;
Myxedema
;
Obesity
;
Obesity, Morbid*
;
Pericardial Effusion
;
Peripheral Nervous System Diseases
;
Puberty, Precocious
;
Thyroid Function Tests
;
Thyroid Gland
;
Thyroxine
2.Two Cases of Acquired Hypothyroidism with Severe Obesity, Short Stature and Cardiomegaly.
So Young KANG ; Woo Sung PARK ; Mi Jin JUNG ; Young Seok LEE ; Seok Gun PARK ; Jeesuk YU
Journal of Korean Society of Pediatric Endocrinology 2003;8(2):189-195
The clinical signs of acquired hypothyroidism are usually manifested insidiously over several months to years. The incidence increases after 6 years of age and peaks at 11 to 18 years of age. The clinical symptoms and signs are fatigue, constipation, decreased growth velocity and delayed bone age, compromised intellectual performance, obesity, myxedema, hyperlipidemia, peripheral neuropathy and delayed or precocious puberty. Two children were referred to our hospital for the evaluation of severe obesity and short stature. During the evaluation we found they also had hyperlipidemia, cardiomegaly with or without pericardial effusion. Thyroid function test revealed decreased serum thyroid hormone levels with positive anti- microsome and anti-thyroglobulin antibodies consistent with long-standing acquired hypothyroidism. After the supplement of L-thyroxine, both of them showed rapid improvement of above symptoms, except for the incomplete catch-up growth. We herein report two cases of acquired hypothyroidism with severe obesity, short stature, hyperlipidemia and cardiomegaly with review of literatures.
Antibodies
;
Cardiomegaly*
;
Child
;
Constipation
;
Fatigue
;
Humans
;
Hyperlipidemias
;
Hypothyroidism*
;
Incidence
;
Microsomes
;
Myxedema
;
Obesity
;
Obesity, Morbid*
;
Pericardial Effusion
;
Peripheral Nervous System Diseases
;
Puberty, Precocious
;
Thyroid Function Tests
;
Thyroid Gland
;
Thyroxine
3.Spontaneous Echo Contrast Mistaken for Left Ventricular Thrombus during Venoarterial Extracorporeal Membrane Oxygenation.
Seok In LEE ; So Young LEE ; Chang Hyu CHOI ; Kook Yang PARK ; Chul Hyun PARK
Korean Journal of Critical Care Medicine 2017;32(4):372-375
No abstract available.
Extracorporeal Membrane Oxygenation*
;
Thrombosis*
4.Autosomal dominant distal hereditary motor neuropathy type II: a Korean family without sequence variation in HSPB1 and HSPB8
Sang-Soo Lee ; So-Young Moon ; Ji-Seon Kim ; Chang-Seok Ki
Neurology Asia 2012;17(3):235-237
Distal hereditary motor neuropathy (dHMN) is a heterogeneous group of disorders characterized by
weakness and wasting of distal limb muscles without overt sensory abnormalities. Recently, autosomal
dominant dHMN has been mapped to chromosome 12q24 and 7q11-q21. We present a family with
autosomal dominant adult onset dHMN type II consisting of fi ve affected individuals spanning three
generations. They developed mild symmetrical distal lower limb weakness, muscle wasting, and severe
foot deformity after the third decade. Genetic analysis showed no support for linkage to chromosome
12q24 and 7q11-q21 in our family. These fi ndings further demonstrate a genetic heterogeneity within
dHMN type II.
5.A Case of Verrucous Condyloma Lata Mimicking Condyloma Accuminata.
Hyojin KIM ; Jeong Nan KANG ; In Ho PARK ; Young Seok LEE ; So Young JUNG ; Jung Eun SEOL ; Ho Suk SUNG
Korean Journal of Dermatology 2014;52(6):445-446
No abstract available.
Syphilis, Cutaneous
6.A Survey on Ostomates With the special reference to physical, psychosocial and sexual problems.
Hyun Seog SO ; Seok Hwan LEE ; Young Gwan KO ; Soo Myung OH ; Choong YOON ; Hoong Zae JOO ; Kee Hyung LEE
Journal of the Korean Society of Coloproctology 1998;14(3):447-454
The survey was undertaken among the 105 ostomates who attended the 2nd Workshop for Stoma Rehabilitation on Aug. 30th, 1997 by the Department of Surgery, Kyung-Hee University Hospital to assess the physical, psychosocial and sexual problems with a stoma. The 97% of ostomates had permanent colostomies following abdominoperineal resection. The 67% of ostomates had one or more physical problems caused by stoma. Frequent bowel movement (94.3%), impairment of irrigation (64.6%), unpleasant odor (27.3%), and urinary frequency (21.3%) were common problems encountered by ostomates. Concerning the psychosocial problems, 3.8% of them suffered from profound restriction of social activities and 1.9% of them had psychologic problems such as depression. 42 of 58 ostomates (72.4%) who were employed before operation returned to their work. Among 71 men, 44 (62%) were impaired by sexual function. Most ostomates suffered physical, social, psychologic and sexual problems in their daily life and needed helps of experts such colorectal surgeons, enterostomal therapists, and ostomy association. Attention is needed more to improve the quality of life for the ostomates.
Colostomy
;
Depression
;
Education
;
Humans
;
Male
;
Odors
;
Ostomy
;
Quality of Life
;
Rehabilitation
7.Cavernous Lymphangioma of the Scrotum: Report of A Case.
Young Goo LEE ; Seok Ho SO ; Nak Kyu CHOI
Korean Journal of Urology 1990;31(5):790-793
A 13-year old boy was seen for progressive enlargement of a right scrotal mass that had been present since early childhood. Scrotal mass was excised and consisted of a well demarcated multinodular cystic soft mass. Pathology was characteristic of cavernous lymphangioma. Lymphangiomas are benign tumors of congenital origin, occurring about 95% of the lesion at neck and axilla. Their scrotal location is quite uncommon. Treatment consists of surgical excision. Unless completely removed, recurrences are common.
Adolescent
;
Axilla
;
Humans
;
Lymphangioma*
;
Male
;
Neck
;
Pathology
;
Recurrence
;
Scrotum*
8.A Case Report: Irbesartan and Naltrexone Treatment of Polydipsia in a Patient with Schizophrenia.
Hyun Seok DONG ; Seung Hyun KIM ; So Young PARK
Korean Journal of Schizophrenia Research 2015;18(2):86-90
Polydipsia in schizophrenic patients is not uncommon, but a frequently underdiagnosed condition. The etiology of polydipsia remains unclear, and its complications can be life-threatening, while often being difficult to manage it. We report a case of a successfully treated chronic schizophrenic patient with polydipsia. The patient was male, 47-year-old, suffering 27-years of residual schizophrenia who had been consuming more than 10 L of water per day, and is complicated by hyponatremia. He was treated with irbesarten 300 mg and naltrexone 50 mg in the setting of closed ward. He consumed less than 3.5 L of water per day and serum sodium levels seemed to be stable following discharge from the closed ward. We suggest that irbesartan and naltrexone may have beneficial effects for treating polydipsia, and future prospective and well-controlled studies are to be performed.
Humans
;
Hyponatremia
;
Male
;
Middle Aged
;
Naltrexone*
;
Polydipsia*
;
Prospective Studies
;
Schizophrenia*
;
Sodium
;
Water
9.Influence of Gating and Attenuation-correction for Diagnostic Performance of Usual Rest/stress Myocardial Perfusion SPECT in Coronary Artery Disease.
Myung Chul LEE ; June Key CHUNG ; Dong Soo LEE ; Kyeong Min KIM ; Young SO ; Jeong Seok YEO ; Gi Jeong CHEON
Korean Journal of Nuclear Medicine 1999;33(2):131-142
PURPOSE: Either gated myocardial perfusion SPECT or attenuation corrected SPECT can be used to improve specificity in the diagnosis of coronary artery disease. We investigated in this study whether gating or attenuation correction improved diagnostic performance of rest/stress perfusion SPECT in patients having intermediate pre-test likelihood of coronary artery disease. MATERIALS AND METHODS: Sixty-eight patients underwent rest attenuation-corrected T1-20l/dipyridamole stress gated attenuation-corrected Tc-99m-MIBI SPECT using an ADAC vertex camera (M:F=29:39, aged 59+/-12 years, coronary artery stenosis> or =70%. one vessel: 13, two vessel: 18, three vessel: 8, normal: 29). Using a five-point scale, three physicians graded the post-test likelihood of coronary artery disease for each arterial territory (1 normal, 2: possibly normal 3:equivocal, 4: possibly abnormal, 5: abnormal). Sensitivity, specificity and area under receiver-operating-characteristic curves were compared for each operator between three METHODS: (A) non-attenuation-corrected SPECT; (B) gated SPECT added to (A); and (C) attenuation-corrected SPECT added to (B). RESULTS: When grade 3 was used as the criteria for coronary artery disease, no differences in sensitivity and specificity were found between the three methods for each operator Areas under receiver- operating-characteristic curves for diagnosis of coronary artery disease revealed no differences between each modality (p>005). CONCLUSION: In patients at intermediate risk of coronary artery disease, gated SPECT and attenuation-corrected SPECT did not improve diagnostic performance.
Coronary Artery Disease*
;
Coronary Vessels*
;
Diagnosis
;
Humans
;
Perfusion*
;
ROC Curve
;
Sensitivity and Specificity
;
Tomography, Emission-Computed, Single-Photon*
10.Two Cases of Henoch-Schonlein Purpura in Brother and Sister at Similar Period.
So Young KIM ; In Seok LIM ; Byoung Hoon YOO
Journal of the Korean Society of Pediatric Nephrology 2000;4(2):161-165
Henoch-Sch nlein purpura(HSP) frequently follows upper respiratory infection, and one of the causes of this disease is inferred to beta-hemolytic streptococcal infection, but the relationship is still unclear. Familial tendency of this disease is unclear, too. Also genetic relationship of this disease has been in a controversy yet. We experienced two cases of HSP in brother and sister at similar period, and report this case with review of related literatures.
Humans
;
Purpura, Schoenlein-Henoch*
;
Siblings*
;
Streptococcal Infections