GH concentration in plasma decline with age. GH and GH response to GHRH are influenced by sex hormones, thereby changing around the menopause. In several aspects, features of aging resemble those of a state of GH deficiency. It has been argued the declining GH function, along with other factors, might be a causal factor in osteoporosis. The purpose of this study was to investigate that postmenopausal osteoporosis in ovariectomized rat could be prevented by rhGH. Fifty-four Sprague-Dawley rats(weight 140-200g) were devided 3 groups. Group 1(n=18) was sham operation; Group 2(n=18) was ovariectomized and received subcutaneous injection with 0.05 cc normal saline; Group 3(n=18) was ovariectomized and received subcutaneous injection with 0.2 IU rhGH. Group 2 and 3 were injected daily, 6 day per week. Each group was devided three subgroups(n=6) and were sacrificed at 6 week, 10 week, 14 week, respectively. Group 2 showed a significant increase in body weight, femur length, serum IGF-1 level, serum PICP and ICTP level at 6 weeks, 10 weeks, 14 weeks and a significant decrease in ash weight of tibia, width of bony spicules, at 14 weeks than Group 1. Group 3 demonstrated a significant increase in body weight, femur length, serum IGF-1, serum PICP and ITCP levels and a insignificant decrease in ash weight of tibia and width of bony spicules, at 6 weeks, 10 weeks, 14 weeks than Group 1. At 14 weeks, Group 3 showed a significant increase in serum IGF-1, Serum PTH, Serum PICP. From these data, we conclude that although rhGH administration leads to an activation of bone turnover and more stimulation of bone formation, it does not prevent a bone loss in ovariectomized rat.
Aging ; Animals ; Body Weight ; Female ; Femur ; Gonadal Steroid Hormones ; Humans* ; Injections, Subcutaneous ; Insulin-Like Growth Factor I ; Menopause ; Osteogenesis ; Osteoporosis* ; Osteoporosis, Postmenopausal ; Ovariectomy ; Plasma ; Rats* ; Rats, Sprague-Dawley ; Tibia

No abstract available.
Spondylolisthesis*

In 1941 Wiberg discribed morphologic classification of patella in axial plane and the correlationship between its shape and dysfunction. Here the authors reviewed 120 cases and divided them into four groups. Group I is the one with no knee joint pain or patella dysfunction, group II is the patients with meniscus injury, gruop III is the patients with chondromalacia of patella and group IV is the patients with osteoarthritis of knee joint. We analysed them according to the ratio between the length of the patella and the articular surface in lateral X-ray films of patella. The results were as follows:1. The ratio between the length of the patella and the articular surface is 1.45±0.13(mean±SD) in group I, 1.47±0.18 in group II, 1.56±0.12 in group lll and 1.57±0.15 in group IV. 2. Statistically(P<0.05), no significant difference between group I and group II, but group III and group IV is significantly different from the group I. 3. The ratio between the length of the patella and the articular surface is thought to be helpful for diagnosing the patient with vague knee joint pain.
Cartilage Diseases ; Classification ; Humans ; Joints ; Knee Joint ; Osteoarthritis, Knee ; Patella ; X-Ray Film

The various methods of treatment of the supracondylar fractures of the femur were adapted by many authors according to degree of the involvement of the articular surface, displacement of fragments, degree of comminution and external forces. Authors experienced the supracondylar fracture of the femur in 31 cases who were treated at Koryo General Hospital from March 1984 until March 1988 and among them, 14 cases were treated by operative methods and 17 cases by conservative methods. The results were as follows:1. The male was more common, and the 3rd & 4th decades were most. 2. The most common cause of injuries was traffic accident. 3. The most common fracture type was type I by Neer's classification. 4. The type I was treated mostly by conservative methods and the type II & III by operative methods. 5. In the operative treatments, after anatomical reduction and rigid fixation, the duration of the rehabilitation was shortened by using the C.P.M. exerciser. 6. The complications were partial ankylosis of the knee, chronic osteomyelitis, nonunion and delayed union.
Accidents, Traffic ; Ankylosis ; Classification ; Clinical Study ; Femur ; Hospitals, General ; Humans ; Knee ; Male ; Osteomyelitis ; Rehabilitation

There are few reports in the literature on how to care and manage bi!ateral congenital dislocation of the hip. Six patients have been encountered at this hospital from June 1979, of them four children had operative treat ment and the other two conservative. As a result of our experience about the management of bilateral congenital dislocation of the hip. The authors obtained the following conceptions; 1. The patient with bilateral dislocation was rather delayed in diagnosis. Therefore, in comp the treatment of bilateral cases was poorer than that of unilateral case. 2. In the case of the dislocated hip that might be easily reduced and maintained in the stab servative care was usually recommeded even in the older child. Unstable, unreduced hip,; hip in old children, the more definitive operation and internal & external rigid immobilization mandatory to get good result. 3. It might be beneficial to operate the more deformed and resistive hip first, and then to p with the same procedure 2 weeks after the first operation.
Child ; Diagnosis ; Dislocations ; Fertilization ; Hip ; Humans ; Immobilization

The Primary objectives of total hip replacement arthroplasty are not only to relieve pain, but to improve motion and function. The range of motion following total hip replacement arthroplasty depends on several factors, especially the position of acetabular cup and femoral stem. Also the oriental need more flexion and abduction in hip motion for squarting position as compared with the European who have different living activity. We studied in vitro biomechanical evaluation of proper position of acetabular cup and femoral stem for T.H.R.A. The following results were obtained: l. Effect of component orientation on R.O.M. 2. Acceptable position of prosthesis was as follows: Acetabular cup: inclination 40–50 degree, anteversion 20–30 degree, Femoral stem: anteversion 0–10 degree. 3. The sum of ideal anteversion of the two components was 30–35 degree 4. Oriental sitting position was performed normally in the ideal position of the prosthesis 5. Acetabular cup is likely insert in the position as far as post sup rim of acetabulum mightbe feasible to be full recovered.
Acetabulum ; Arthroplasty ; Arthroplasty, Replacement, Hip ; Hip ; In Vitro Techniques ; Prostheses and Implants ; Range of Motion, Articular

No abstract available.
Giant Cell Tumor of Bone* ; Giant Cell Tumors* ; Giant Cells*

No abstract available.
Compartment Syndromes*

PURPOSE: We compared the safety and efficacy of ureteroscopy with intravenous propofol anesthesia with those with spinal anesthesia for the treatment of lower ureteral calculi. MATERIALS AND METHODS: Ureteroscopy with intravenous propofol anesthesia was performed in 38 patients with ureteral caluli, and spinal anesthesia was performed in 41. Ureteroscopy was performed with a 9.5Fr rigid ureteroscope. RESULTS: The overall success rate of stone removal was 99% (100% in IV propofol anesthesia cases and 98% in spinal anesthesia cases). Hospital stay times were significantly shorter for patients given propofol: 1.5 vs 3 days, respectively(p<0.05). CONCLUSIONS: Stone removal under intravenous propofol anesthesia does not increase the risk of complication or compromise the results of treatment and hospital stay times.
Anesthesia* ; Anesthesia, Intravenous ; Anesthesia, Spinal ; Endoscopy ; Humans ; Length of Stay ; Propofol* ; Ureter* ; Ureteral Calculi* ; Ureteroscopes ; Ureteroscopy*

No abstract available.
Fractures, Open*