No abstract available.
Colorectal Neoplasms* ; Humans ; Male*

No abstract available.
Coxa Vara* ; Follow-Up Studies*

The cruciate ligaments are important in providing the anterior and posterior stability and usually associated with other ligament injury of the knee joint, and there are many controversies in its treatment. In general, the primary repair for the acute cruciate ligament injury was good, but some had opposite opinions in the treatment of the isolated anterior cruciate ligament injury. In acute injury, early repair of ligament and in delayed case, the reconstrution surgery of ligament was recommended. For good results, it is very important to give prompt management. Authors studies 23 cases in 16 patients with acute cruciate ligament proper injury who were treated by multiple pull out technique at the department of orthopaedic surgery, Chungnam National University Hospital from April, 1984 to July, 1988. The results were as followings: 1. The incidence was high in active male patients. 2. The most common injury was the traffic and automobile accident. 3. the tibial and femoral attachment were the most common detachment site in anterior and posterior cruciate ligament injury, respectively. 4. Isolated cruciate ligament injury was rare. 5. The results were good in 11 cases(47.8%), especially treated within one week.
Anterior Cruciate Ligament ; Automobiles ; Chungcheongnam-do ; Humans ; Incidence ; Knee Joint ; Ligaments ; Male ; Posterior Cruciate Ligament

No abstract available.
Giant Cell Tumors* ; Giant Cells* ; Knee Joint* ; Knee*

No abstract available.
Precursor Cell Lymphoblastic Leukemia-Lymphoma*

No abstract available.
Cardiomyopathy, Dilated*

No abstract available.
Pancytopenia* ; Pneumonia*

Male breast cancer is very rare, with the incidence of 0.15-1% of all breast cancers and less than 1% of all cancers in men. The prognosis of male breast cancer is poorer than that of female because the median age of detection of the disease is in more late stage. It usually involves higher axillary lymph nodes. We report two cases of male breast cancer to describe characteristic mammographic and ultrasonographic findings and to compare with the findings of gynecomastia.
Breast ; Breast Neoplasms, Male* ; Female ; Gynecomastia ; Humans ; Incidence ; Lymph Nodes ; Male ; Male* ; Prognosis

BACKGROUND: Histamine, released from mast cells in atheromatous plaque, has been known to cause cardiac ischemia or sudden cardiac death in atherosclerosis patient. Previous reports have suggested that histamine induced coronary vasoconstriction was due to increase in IP(3) and DAG, which induce release of Ca2+ from SR and increase the Ca2+ sensitivity of contractile element via activation of PKC. Recently, it was reported that application of histamine cause depolarization of intestinal smooth muscle, which may contribute to histamine-induced contraction via augmenting Ca2+ influx through activation of Ca2+ channels. However, the underyling mechanism of histamine-induced depolarization and its contribution to the magnitude of coronary vasoconstriction are still uncertain. METHOD: To elucidate the underlying mechanism of Ca2+ influx change during histamine-induced vasoconstriction, we examined the effect of Ca2+ channel antagonist and PKC blocker on histamine-induced contractions, and then measured the effect of PKC antagonist on whole cell K+ current using patch clamping method in rabbit coronary smooth muscle cells. RESULTS: Application of histamine induced phasic and tonic constraction of coronary rings via activation of H(1) receptors. Pretreatment of Ca2+ channel antagonist (nifedipine, 1 microM) or PKC blockers (10 nM staurosporine and 10 microM Go6976) markedly inhibited histamine-induced tonic contraction, which suggest that the magnitude of tonic contraction depend on the Ca2+ influx. Application of 4-AP, a blocker of voltage-dependent K+ channels, increased resting tone of coronary rings, and combined treatment of nifedipine blocked this 4-AP induced increase of resting tone. Application of active analoge of DAG (1,2-DiC(8)) significantly inhibited the activity of voltage-dependent K+ current in single smooth muscle cell, meanwhile the inactive analogue of DAG (1,3-DiC(8)) has no apparent effect on the activity of voltage-dependent K+ current. Furthermore, pretreatment of calphostin C (1 microM), a blocker of PKC, diminished the 1,2-DiC(8)-induced inhibition of K+ current. CONCLUSION: PKC dependent inhibition of voltage-dependent K+ current may be responsible for the maintaining of histamine-induced tonic contraction in rabbit coronary artery.
Atherosclerosis ; Constriction ; Coronary Vessels* ; Death, Sudden, Cardiac ; Histamine ; Humans ; Ischemia ; Mast Cells ; Muscle, Smooth ; Myocytes, Smooth Muscle ; Nifedipine ; Protein Kinase C ; Staurosporine ; Vasoconstriction

No abstract available.
Meningitis* ; Mycoplasma pneumoniae* ; Mycoplasma* ; Pneumonia* ; Pneumonia, Mycoplasma*