1.Lymphokine-activated killer(LAK) cell activity in tumor-transplanted mice(II).
Sang Yun NAM ; Yun Tai LEE ; Young Il KIM ; Si Young KIM ; Kyung Sam CHO
Journal of the Korean Cancer Association 1992;24(3):365-377
No abstract available.
2.Lymphokine-activated killer(LAK) cell activity in tumor-transplanted mice(I).
Sang Yun NAM ; Yun Tai LEE ; Young Il KIM ; Si Young KIM ; Kyung Sam CHO
Journal of the Korean Cancer Association 1991;23(2):218-229
No abstract available.
3.Fibrous Pseudotumor of the Testicular Tunics: Two case reports.
Seung Sam PAIK ; Nam Hoon KIM ; Young Hyeh KO ; Moon Hyang PARK
Korean Journal of Pathology 1995;29(4):533-535
Fibrous pseudotumor of the testicular tunics is a rare benign fibrous proliferative disorder, but it is the second most common mass-forining lesion of the testicular tunics. While these lesions are not strict neoplasms, they do form nodules and are often mistaken for neoplasms. Herein, we report 2 cases of fibrous pseudotumor with characteristic histologic findings. Both cases had been incidentally found as slow growing scrotal masses and underwent excision. There were several nodules along the testicular tunics which had bulging whitish-gray cut surface with focal myxoid change and a whorling appearance. These two cases showed the histologic spectrum seen in fibrous pseudotumor from a haphazard arrangement of fibroblastic type cells with intervening collagen and focal lymphocytic infiltrates in case 1, to a densely collagenized lesion in case 2.
4.Clinical Experience of Extracorporeal Shock Wave Lithotripsy with Tripter Compact(R) Lithotriptor.
Young Hwa YOON ; Sam Keuk NAM ; Soon Chan KIM
Korean Journal of Urology 1999;40(5):537-541
PURPOSE: Extracorporeal shock wave lithotripsy(SWL) is currently prorposed for the first line treatment of most renal and ureteral stones. In general, SWL is very effective and non-invasive method than open surgery or endoscopic lithotripsy. We experienced 350 cases of SWL for 46 months and announced it. MATERIALS AND METHODS: We retrospectively reviewed the data of 324 patients(350 stones) who had been diagnosed as renal or ureteral stones and underwent SWL using Tripter Compact(R) lithotriptor from September 1994 to July 1998. Male to female ratio was 1.9:1 and patient`s ages ranged from 18 to 82 years(mean 43.7 years). We underwent SWL only with parenteral analgesics for pain control. RESULTS: In 350 stones, renal stones were 90 cases(25.7%) and ureteral stones were 260 cases(74.3%). In 90 renal stones, calyceal stones(include 1 staghorn stone) were 62 cases(68.9%) and renal pelvic stones were 28 cases(31.1%). In 260 ureteral stones, upper ureteral stones were 209 cases(80.4%), mid ureteral stones were 10 cases(3.8%), and lower ureteral stones were 41 cases(15.8%). The stones from 10 to 19mm in diameter were the majority of renal stones(53.3%), whereas in ureter, the stones smaller than 10mm in diameter were most common(41.5%). Less than 3 treatment sessions were needed for 147 cases(93.0%) of stones smaller than 10mm and for 146cases(76.0%) stones larger than 10mm. Less than 3 sessions were needed for 68 cases(75.6%) of renal stones and for 225 cases(86.5%) of ureteral stones. All renal stones were fragmented and the success rate for upper ureteral stones was 93.3%(195/209), for mid ureteral stones was 80.0%(8/10), and for lower ureteral stones was 80.5%(33/41). According to the size of stone, the success rate for the stones smaller than 10mm in diameter was 96.2%(152/158) and for the stones larger than 10mm was 90.6%(174/192). Total success rate was 93.1%(326/350). The complications after SWL were gross hematuria over 24hours(64 cases, 18.3%), flank pain(52 cases, 14.9%), gastrointestinal disturbances(7 cases, 2%), and Steinstrasse(31 cases, 8.9%). The causes of failure were incomplete fragmentation(21 cases, 87.5%) and mucosal impact(3 cases, 12.5%) of stones. Re-treatment rate was 59.7% and auxiliary procedure rate was 8.0%(efficiency quotient was 0.56). CONCLUSIONS: Our experiences shows extracorporeal shock wave lithotripsy is a safe and effective method for the treatment of renal and ureteral stones, and we expect the better outcome by development of techniques and equipments.
Analgesics
;
Female
;
Hematuria
;
Humans
;
Lithotripsy*
;
Male
;
Retrospective Studies
;
Shock*
;
Ureter
;
Urinary Calculi
5.A Clinical Experience of Radical Hysterectomy on 398 Cases of Locally Invasive Cervical Cancer.
Young Nam KIM ; Dae Hoon CHUNG ; Young Sam KIM ; Kyung Bok LEE ; Ki Tae KIM ; Hyun Chan KIM
Korean Journal of Gynecologic Oncology and Colposcopy 2000;11(4):369-380
OBJECTIVE: To survey the clinical features, complications, prognostic factors and Five-year survival rates of 398 patients with invasive cervical cancer(stage Ib-IIb), subjected to radical hysterectomy and bilateral pelvic lymphadenectomy. METHODS: Medical records and pathologic reports were reviewed retrospectively on 398 cases, diagnosed and operated on during the period of Jan. 1988 - Dec. 1998. Five-year survival rates were estimated by the Kaplan-Meier method, and prognostic factors were assessed using Wilcoxon test. RESULTS: Of the 398 cases, 285 were in stage Ib(71.6%), 58 in stage IIa(14.5%), and 55 in stage IIb(13.8%). The mean age of patients was 48+/-9.9 years. Neoadjuvant chemotherapy was given to 200 patients(50.2%), Adjuvnat radiotherapy in 160 patients(40.2%) postoperatively. Operative complications occured in 121 patients(30%). Massive blood loss and bladder dysfuction were frequent complications(11.3% and 10.3%, respectively). Others were urinary tract infection(9.3%), wound infection(7.5%), lymphocyst(3.5%) and urinary tract fistula(0.7%), respectively. The Five-year survival rates for stage Ib, IIa, and IIb were 84.2, 82.8%, and 75.8%, respectively. Factors that affect the Five-year survival rates were cell type(small cell Vs other, P=0.0146), tumor size(< or = 3cm Vs >3cm, P=0.0425), depth of invasion( < or = 5gm Vs >5ne, P= 0.0007), response of chemotherapy(poor response Vs other, P= 0.0001), LN metastasis(1 Vs 2 Vs more, P=0.0001). CONCLUSION: Accumulating the clinical experience, we could improve results, reduce complications and speculated that the survival rates could be improved by neoadjuvant chemotherapy and/or adjuvant postoperative radiotherpy. Prospective randomized trials are needed to evaluate our approach and to be compared with concurrent chemoradiotherapy to definite its precise role in locally advanced cervical cancer.
Chemoradiotherapy
;
Drug Therapy
;
Humans
;
Hysterectomy*
;
Lymph Node Excision
;
Medical Records
;
Radiotherapy
;
Retrospective Studies
;
Survival Rate
;
Urinary Bladder
;
Urinary Tract
;
Uterine Cervical Neoplasms*
;
Wounds and Injuries
6.A Case of Paratesticular Embryonal Rhabdomyosarcoma.
Sinn JEONG ; Won Joon BHANG ; Tae Hyung RHO ; Young Chul YOON ; Soo Chan KIM ; Sam Keuk NAM
Korean Journal of Urology 2000;41(11):1415-1417
No abstract available.
Rhabdomyosarcoma, Embryonal*
7.A Case of Extra-adrenal Pheochromocytoma.
Chang Su JUNG ; Jun Tak PARK ; Young Hwa YOON ; Soon Chan KIM ; Sam Keuk NAM
Korean Journal of Urology 1997;38(3):315-318
Pheochromocytoma is one of the surgically curable hypertensive diseases and can arise wherever chromaffin cells are located. Herein, a case of extra-adrenal pheochromocytoma developed in a 51 year-old male is presented with brief review of literatures.
Chromaffin Cells
;
Humans
;
Male
;
Middle Aged
;
Pheochromocytoma*
8.A Case of Rhabdomyosarcoma of the Bladder in an Old Adult.
Young Tai KANG ; Joo Kyun PARK ; Woo Chul SUN ; Sam Geuk NAM ; Jae Heung CHO
Korean Journal of Urology 1983;24(6):1117-1120
An unusual case of embryonal rhabdomyosarcoma of the bladder in a 77 year old man, who presented with difficult urination, gross hematuria and vague lower abdominal pain. Herein, we report a case of rhabdomyosarcoma. which revealed early recurrence and rapid growing up after partial cystectomy.
Abdominal Pain
;
Adult*
;
Aged
;
Cystectomy
;
Hematuria
;
Humans
;
Recurrence
;
Rhabdomyosarcoma*
;
Rhabdomyosarcoma, Embryonal
;
Urinary Bladder*
;
Urination
9.Multifocal ischemic lesions and focal hematoma formation in a meningitis.
Hye Young KWON ; Dae Woong CHUN ; Hoo Won KIM ; Sam Nam HONG ; Jeong Hoon JANG ; Ai Young LEE ; In Kyu YU
Journal of the Korean Neurological Association 1997;15(5):1189-1194
Cerebrovascular complications are of the most frequent intracranial complications of bacterial meningitis. Most of the previous reports suggest that the prognosis for the pafients with cerebrovascular complications was unfavorable. We recently experienced a case of meningococcal meningitis with fulminant meningococcemia associated with multifocal non-enhancing lesions on, initial brain MRI. These lesions were hyperintense on T2weighted image and were located in left basal ganglia, both medial thalami, periventricular white matter, left cerebellar hemisphere, and right midbrain and were considered to be resulted from small vessel involvement. Gram negative diplococci were detected by Gram staining of specimens from skin lesion. After antimicrobial therapy and glucocorticoid replacement the patient was recovered without any neurologic sequelae. After one month, follow-up MRI showed resolution of all the ischemic lesions except in midbrain. Additionally there was a small focal hemtoma formation in left basal ganglia. The small hematoma was considered to be resulted from rupture of microaneurysm and disappeared on follow up MRI performed after 3 months. This case suggests that the cerebrovascular complications in meningococcal mningitis might be treated successfully.
Basal Ganglia
;
Brain
;
Follow-Up Studies
;
Hematoma*
;
Humans
;
Magnetic Resonance Imaging
;
Meningitis*
;
Meningitis, Bacterial
;
Meningitis, Meningococcal
;
Mesencephalon
;
Prognosis
;
Rupture
;
Skin
10.Detection of Bartonella henselae DNA by Polymerase Chain Reaction in a Patient with Cat Scratch Disease: A Case Report.
Ju Young CHUNG ; Tae Hee HAN ; Baek Nam KIM ; Young Sam YOO ; Seong Jig LIM
Journal of Korean Medical Science 2005;20(5):888-891
We report a case of cat scratch disease caused by Bartonella henselae in Korea. A 25-yr-old woman developed left cervical lymphadenopathy with history of contact with a dog. The cervical lymphadenopathy persisted for 1 month and resolved gradually and spontaneously. Serologic test was not done during the acute stage of the disease. Immunofluorescent antibody test performed during the convalescent stage was positive for B. henselae. To confirm B. henselae infection, polymerase chain reaction (PCR) analysis using aspirates of cervical lymph node was performed and the presence of B. henselae DNA was demonstrated. This is the first reported case of cat scratch disease in Korea confirmed by PCR for B. henselae DNA.
Adult
;
Bartonella henselae/*genetics/*isolation and purification
;
Cat-Scratch Disease/*diagnosis/*microbiology
;
DNA, Bacterial/*analysis/*genetics
;
Female
;
Humans
;
Polymerase Chain Reaction/*methods