No abstract available.
Arteriovenous Malformations ; Neck

Twelve patients with inflammatory bowel disease had been operated at the department of surgery, Chonnam University Hospital during the period from March 1988 to February 1997. In this study, we report on the operative cases regarding age, sex, symptoms, duration of disease, location of disease, preoperative diagnosis, operative indication, frequency of operation, histopathologic findings and follow up. The results were as follows: 1) The male to female ratio in ulcerative colitis was 1 : 1, and the mean age was 54.5 years. In Crohn's disease, male to female ratio was 2.3 : 1 and the mean age was 42.1 years. 2) The mean duration of symptoms in ulcerative colitis was 39 months and in Crohn's disease was 13.9 months. The common symptoms in ulcerative colitis were abdominal pain, bloody diarrhea, indigestion, weight loss and in Crohn's disease abdominal pain, palpable mass, weight loss, indigestion. Extraintestinal symptoms in Crohn's disease were cholelithiasis like symptom, anal fistula, anal fissure. 3) The involvement site in ulcerative colitis was large bowel only, but in Crohn's disease small bowel (50%), large bowel (20%), small and large bowel (30%) were involved. 4) Preoperative diagnosis in ulcerative colitis was accurate, but in Crohn's disease accurate diagnosis was made only in 20% and the other cases were operated under the impression of different diseases or conditions (intestinal tuberculosis (50%), bowel perforation (20%), mechanical ileus (10%)). 5) The indication of surgery in ulcerative colitis was intractability to medical treatment, on the other hand, in Crohn's disease most operative cases were made under the emergentconditions (bowel perforation, bowel obstruction, enterocutaneous fistula, abdominal mass). The frequency of operation in ulcerative colitis were two times in one case, three times in one cases. In Crohn's disease half of cases experienced two or three times of surgery. The method of operation in ulcerative colitis was total proctocolectomy with J-pouch ileoanal anastomosis. In Crohn's disease resection of diseased bowel segment was performed.
Abdominal Pain ; Cholelithiasis ; Colitis, Ulcerative ; Colonic Pouches ; Crohn Disease ; Diagnosis ; Diarrhea ; Dyspepsia ; Female ; Fissure in Ano ; Follow-Up Studies ; Hand ; Humans ; Ileus ; Inflammatory Bowel Diseases* ; Intestinal Fistula ; Jeollanam-do ; Male ; Rectal Fistula ; Tuberculosis ; Weight Loss

Colorectal carcinoma in patients under 40 years and over 70 years of age is unusual but not rare. The prognosis of these two groups, compared with remainder of patients, is thought to be unfavorable. From Jan. 1981 to Dec. 1997, 541 patients with primary colorectal cancer who were treated by surgical resection were analyzed retrospectively. They were divided into three age groups according to the age at admission, i.e. under 40 years, over 70 years and between 40 and 69 years(control group). Among three age groups, sex ratio, tumor characteristics(size, location , depth of invasion, lymph node metastasis, liver metastasis, peritoneal metastasis, histopathologic classification, stage, DNA ploidy pattern), serum CEA level and survival were compared and analyzed. The results were as follows: 1) In the young patient group(52 cases), female predominence, large tumor size, high proportion of mucinous adenocarcinoma in histopathologic classification, more frequent metastasis to regional lymph node, frequent peritoneal metastasis and high incidence in tumor location at transverse colon were noted(p<0.05). 2) In the elderly group(69 cases), deep invasion of tumor(T4) was noted (p<0.05). In addition, among them, concomittent diseases were presented in 25 patients(36%). They were diabetes(8), cardiac arrhythmia(4), old myocardial infarction(2), liver cirrhosis(5), COPD(3), previous cancer(3). 3) The 5-year survival rates of the young patient group and that of elderly patient group were lower than that of the other(p<0.01). 4) There was no significant differences in liver metastasis, tumor stage, DNA ploidy pattern, serum CEA level among three age groups.
Adenocarcinoma, Mucinous ; Aged* ; Classification ; Colon, Transverse ; Colorectal Neoplasms* ; DNA ; Female ; Humans ; Incidence ; Liver ; Lymph Nodes ; Neoplasm Metastasis ; Ploidies ; Prognosis ; Retrospective Studies ; Sex Ratio ; Survival Rate

No abstract available.

Recently, abnormalites in DNA content have been considered as a new prognostic factor in gastric cancer. However, whether abnormal DNA content can be used as a prognostic tool for gastric cancer is still unknown .For that reason, the relationship between the DNA ploidy pattern and the conventional clincopathologic findings was studied and the corresponding survival rates were compared. A group of 690 newly diagnosed and surgically resected gastric cancer specimens obtained from January 1986 to June 1996 were examined for DNA content by flow cytometry. The results showed that 411 cases (59.6%) had DNA diploidy and 279 cases (40.4%) had aneuploidy; DNA aneuploidy was significantly correlated to well differentiated adenocarcinoma, whereas diploidy was correlated to signet ring cell carcinoma. The DNA diploidy group was differentiated from the aneuploidy group by depth of invasion and nodal involvement. Tumor cells confined to mucosa and no involvement of the lymph node (N0) were significant in the diploidy group of gastric cancer. In addition, stage Ia was predominant in the diploidy group. However the results of surgical resection and the 5-year survival rates of patients in the two groups were not signifcantly different (p>0.05). We, therefore, propose that the DNA ploidy pattern is useful for evaluating tumor growth, including lymph-node involvement, but not for determining the survival and prognosis.
Adenocarcinoma ; Aneuploidy ; Carcinoma, Signet Ring Cell ; Diploidy ; DNA* ; Flow Cytometry ; Humans ; Lymph Nodes ; Mucous Membrane ; Ploidies* ; Prognosis ; Stomach Neoplasms* ; Survival Rate

PURPOSE: The aims of this study are to evaluate the outcome of treatment for developmental dislocation of the hip (DDH) in children under the age of 24 months who underwent open reduction (OR) or closed reduction (CR) and to determine radiologic prognostic factor. MATERIALS AND METHODS: A total of 90 hips of 88 children under the age of 24 months treated for DDH were included. The treatments for these children were CR in 29 hips and OR in 61 hips. All patients were followed up for more than 5 years. Radiographic evaluations, including acetabular index (AI), Yamamuro's distance a and b, center-edge angle (CEA), sourcil shape, and teardrop shape have been proposed to indicate the degree of DDH. Hips were reclassified according to the Severin criteria (classes I and II, satisfactory; classes III and IV, unsatisfactory). RESULTS: Among the 90 hips, 67 hips (74.4%) were included in the ‘satisfactory group’, while 23 hips (25.6%) were included in the ‘unsatisfactory group’. In the CR group, 23 hips (79.3%) were included in the ‘satisfactory group’, while 6 hips (20.7%) were included in the ‘unsatisfactory group’. In the OR group, 44 hips (72.1%) were included in the ‘satisfactory group’, while 17 hips (27.9%) were included in the ‘unsatisfactory group’. There was no significant difference between the reduction methods. At 1 year follow-up after reduction, the AI improvement in the ‘satisfactory group’ (8.1° [23.4%]) was significantly higher than that in the ‘unsatisfactory group’ (6.7° [18.5%]) (p=0.012). A significant difference of the mean CEA values was observed between the ‘satisfactory group’ and the ‘unsatisfactory group’ 3 years after the treatment (p=0.001). Five years after reduction, the V shape of teardrop and the upward shape of acetabular sourcil were observed in 2 hips (3.0%) and 4 hips (6.0%) of the ‘satisfactory group’, respectively, whereas the corresponding findings were observed in 3 hips (13.0%) and 5 hips (21.7%) of the ‘unsatisfactory group’, respectively (p=0.023, 0.005). CONCLUSION: The improvement of AI at 1-year and CEA at 3-year follow-ups, as well as teardrop shape and sourcil shape at 5-year followup, were reliable radiographic prognostic factor of DDH.
Acetabulum* ; Child ; Dislocations* ; Follow-Up Studies ; Hip* ; Humans

PURPOSE: Gastric cancer is considered to be a disease of the middle aged and elderly, but there was increased interest in clinicopathologic features of both the young aged and the old aged gastric cancer. MATERIALS AND METHODS: In an attempt to compare the young below 35 years old with the old over 70 years old about the clinicopathologic characteristics, we reviewed 110 young patients and 146 old patients who were experienced at the Department of Surgery, Chonnam University Hospital from July 1982 to June 1997. We have analyzed the age, sex ratio, location, size, number of the cancer, Borrmanns classification, histologic classification, stage of the cancer, DNA ploidy, curative resectibility, 5 year survival rate in both groups. Comparisons of outcomes between groups were done using z(2) analysis. P value of <.05 was considered significant. A statistical test of the survival rates was made with the Z test and Kaplan-Meier method. Other statistics were analyzed by the log-rank method. RESULT: In the old, the incidence af the gastric cancer was higher in man than in woman(2.24: 1). In the young, the male to female sex ratio was 1: 1.16. The antrum was the most common site of gastric cancer in both groups. The cardia was more frequently involved in the young than the old(17.3%:7.5%). In the histologic classification, tubular adenocarcinoma was the most common in both groups. The young had 17.3% of incidence of signet ring cell carcinoma, but 2.7% in the old. The incidence of the early gastric cancer was 20.0% in the young and 17.8% in the old, which was not significantly different. The incidence of Borrmann type III was predominant in both groups. In Borrmann type IV, the young was revealed 18.0%, the old was revealed 8.2%, but there was no significant difference statistically. There were no significant differences in the stage and 5-years survival rate of the gastric cancer in both groups. CONCLUSION: This study showed the differences between the young and the old in the sex ratio, location, histological types of the gastric cancer. It meaned that there were some differences between the both groups in the etiology of gastric cancer, development and progression patterns.
Adenocarcinoma ; Adult ; Aged ; Carcinoma, Signet Ring Cell ; Cardia ; Classification ; DNA ; Female ; Humans ; Incidence ; Jeollanam-do ; Male ; Middle Aged ; Ploidies ; Sex Ratio ; Stomach Neoplasms* ; Survival Rate

An umbilical omphalomesenteric duct polyp arises from remnants of the omphalomesenteric duct, which connects the midgut to the Yolk sac of the embryo and is closed completely at 7 weeks. Persistence of the omphalomesenteric duct shows various clinical manifestations of embryologic anomalies such as umbilical enteric fistula, Meckel's diverticulum or vitelline cysts. In particular, the umbilical omphalomesenteric duct polyp should be clinically discerned from persistent granulation tissue or pyogenic granuloma and attention should be given to external openings with discharge, which can be suggestive of underlying anomalies. We herein report an case of an umbilical omphalomesenteric duct polyp in a 10-year-old male who had no underlying anomalies.
Child ; Embryonic Structures ; Fistula ; Granulation Tissue ; Granuloma, Pyogenic ; Humans ; Male ; Meckel Diverticulum ; Polyps* ; Vitelline Duct* ; Vitellins ; Yolk Sac

Multiple primary cancer is relatively rare disease. But its study revealed a aspect of carcinogenesis and has changed our concept in second primary cancer. It is not a metastasis or recurrent cancer. Multiple primary cancer associated with gastric cancer is most common in Korea. Now we report two cases of multiple primary cancer in esophagus and stomach, successfully treated.
Carcinogenesis ; Esophagus* ; Korea ; Neoplasm Metastasis ; Neoplasms, Second Primary ; Rare Diseases ; Stomach Neoplasms ; Stomach*

PURPOSE: Kimura's disease is an uncommon, chronic inflammatory disorder of unknown etiology which occurs predominantly in Orientals and presents with tumor-like swellings mainly in the head and neck region. Orbital and ocular adnexal cases are rare. We report a case of Kimura's disease of the eyelid. METHODS: A 52-year-old male presented with a 10-year history of intermittently recurrent swelling and a painless mass of the left upper eyelid. The mass was resected and biopsied for histological examination. RESULTS: The case was diagnosed with Kimura's disease by the clinical and histopathologic findings.
Eyelids* ; Head ; Humans ; Male ; Middle Aged ; Neck ; Orbit