1.Multidrug-resistant Tuberculosis.
Journal of the Korean Medical Association 1998;41(5):529-534
No abstract available.
Tuberculosis, Multidrug-Resistant*
2.Multidrug-resistant Tuberculosis.
Journal of the Korean Medical Association 1998;41(5):529-534
No abstract available.
Tuberculosis, Multidrug-Resistant*
3.Accessory Axillary Breast Tissue.
Hong Jig KIM ; Young Keun KIM ; Hyung Chan PYO
Korean Journal of Dermatology 1986;24(3):460-463
We have experienced a case of the more unusual form of supernumerary breast tissue which is characterized by the presence of aberrant gland tissue alone. The case was a 30-year-old female patient in puerperium with bilateral axillary masses of seven years duration. Gentle pressure over the right-sided one caused milk to exude from a skin pore. Histopathologic findings of the tumors revealed the lobules of the breast forming islands of glandular tissue.
Adult
;
Breast*
;
Female
;
Humans
;
Islands
;
Milk
;
Postpartum Period
;
Skin
4.Transplantation of Cultured Keratinocytes in Autologous Fibrin Glue Suspension.
Jin Young KIM ; Sung Pyo HONG ; Jae Kyung PARK
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1999;26(4):531-537
The use of a cultured autologous keratinocyte sheet has become a recognized method for the coverage of extensive bums during recent years. The disadvantages of these sheet grafts are a long time-lag until keratinocyte sheets are available, the fragility and difficulty in handling of grafts, an unpredictable take rate and extremely high costs. In this study we investigated the transplantation of cultured keratinocytes as single cells suspended in autologous fibrin glue. In a rat model with standardized full thickness wounds, this new transplantation technique was evaluated and compared directly to the conventional keratinocyte sheet grafting technique. After transplantation, wounds were evaluated for the degree of epithelial coverage, and then microscopic structures were evaluated under light and electron microscopy. The results were as follows: 1) The fibrinogen solution prepared from autologous blood had 12 times more fibrinogen compared to the original blood. 2) After transplantation of cultured keratinocyt-es in fibrin glue, the degree of epithelial coverage was 79% at 2 weeks, which was comparable to 17% for cultured keratinocyte sheet graft 3) Typical basement membrane structures were consistently found at 2 weeks after transplantation of keratinocytes in fibrin glue. 4) Rete ridges were found at 4 weeks after transplantation of keratinocytes in fibrin glue. In conclusion, the transplantation technique of keratinocytes in fibrin glue is available earlier than sheet grafts, it transfers actively proliferating cells and it simplifies the grafting procedure. As well, this technique leads to an earlier epithelial covering and an earlier restoration of the dermo-epidermal junction than sheet grafting.
Basement Membrane
;
Fibrin Tissue Adhesive*
;
Fibrin*
;
Fibrinogen
;
Keratinocytes*
;
Microscopy, Electron
;
Models, Animal
;
Transplants
;
Wounds and Injuries
5.The Effect of Decreased Serum Glucose on Collagen Contents of Penile Tunica Albuginea and Endothelial Change of Corpus Cavernosum in Long Evans Rat.
Hyun Pyo HONG ; Dae Yul YANG ; Ha young KIM
Korean Journal of Urology 2001;42(6):650-656
PURPOSE: It is reported that 65% of diabetic male patients over 60 of their age are impotent. However, there is no report concerning the effect of serum glucose control on erectile dysfunction in diabetic patient. This study was performed to evaluate the effects of serum glucose control on erectile dysfunction. MATERIALS AMD METHODS: The development of Diabetes mellitus was defined that the serum glucose level was above 200mg/dL in random test at 25 weeks. We designed the experimental specimen into 3 groups; group I: diabetic OLETF (Otsuka Long Evans Tokushima Fatty) rats without blood sugar control (n=10), group II: diabetic OLETF rats with blood sugar control with 4U insulin subcutaneous injection daily from 26 to 46 weeks (n=10), group III: diabetic OLETF rats with blood sugar control with 10U insulin subcutaneous injection daily from 26 to 46 weeks (n=10). We estimated the collagen content of penile tunica albuginea with the scanning electron microscopy and observed the endothelial layers of corpus cavernosum with the transmission electron microscopy in each group. RESULTS: The serum glucose level was 249 +/- 4.1mg/dL, 234 +/- 2.7mg/dL, 215 +/- 3.0mg/dL respectively in group I, II, III, and decreased in order of group II, III. The differences among groups were statistically significant (p<0.05). The thickness of collagen bundles of penile tunica albuginea was 0.98 +/- 0.1 micrometer, 0.94 +/- 0.3 micrometer, 0.92 +/- 0.1 micrometer respectively in group I, II, III, and decreased in order of group II, III. The differences among groups were statistically significant (p<0.05). The endothelial layers of corpus cavernosum were decreased in II, III. CONCLUSIONS: The serum glucose control in diabetic rats decreases the collagen con tents in penile tunica albuginea and the endothelial layers of corpus cavernosum.
Animals
;
Blood Glucose*
;
Collagen*
;
Diabetes Mellitus
;
Endothelium
;
Erectile Dysfunction
;
Humans
;
Injections, Subcutaneous
;
Insulin
;
Male
;
Microscopy, Electron, Scanning
;
Microscopy, Electron, Transmission
;
Rats*
;
Rats, Inbred OLETF
6.A Case of Kyrle's Disease in a Patient with Chronic Renal Failure.
Hong Jig KIM ; Young Keun KIM ; Hyung Chan PYO
Korean Journal of Dermatology 1987;25(5):703-707
We present a case of Kyrle's disease. The pstient was a 48-year-old male who had been undergoing hemodialysis for 6 years due to chronic renal failure caused by polycystic kidney. The lesions were hyperkeratotic papules on the lower legs and abdomen witb 3 months' duration. Histopathologically, the epidermis showed central invsgination filled with heavy keratotic, partly parakeratotic plug, basophilic debris and neutrophils. There were a few premature keratinized cells below the parakeratotic plugs and complete epidermal perforation was present.
Abdomen
;
Basophils
;
Epidermis
;
Humans
;
Kidney Failure, Chronic*
;
Leg
;
Male
;
Middle Aged
;
Neutrophils
;
Polycystic Kidney Diseases
;
Renal Dialysis
7.Determination of High Density Lipoprotein Cholesterol in Psoriasis Patients.
Joon Young SONG ; Kyu Suk LEE ; Jin Pyo HONG
Korean Journal of Dermatology 1986;24(4):493-498
In orper to measure the levels of high density lipoprotein cholesterol in psoriasis, 60 psoriatic patients and 30 healthy subjects were included in this study. Lopez-Virells methos was applied for measuring the serum level of high density lipoprotein cholesterol. The results were obtained as follows. The level of serurn HDL cholesterol was 58. 39+17. 40 mg/dl in psoratcs and 50.3+0.31 mg/dl in healthy subjects and 50. 43+ 10. 31 mg/dl in healthy subjects. No significant differences were noted between psoriatics & healthy subjects. 2. The level of serum HDL cholesterol was 56. 40+19. 10 mg/dl in male group of psoriatics and 60. 00+15.47 mg/dl in female group of psoriatics and 48.3+9. 50 mg/dl in healthy male group and 52.60 -10.59 mg/dl in healthy female group. No significant differences of serum HDL cholesteol levels were noted in both sexes.3. The mean value of serum HDL cholesterol by age groups of 10, 20, 30, 40, and 50 years old with psoriasis were 50. 70 mg/dl, 61. 97 mg/dl, 57. 44 mg/dl, 49. 11 mg/dl and 70. 36 mg/dl, respectively and those of healthy groups were 57. 25 mg/ dl, 45. 17 rng/dl, 50. 97 rng/dl, 48. 07 mg/dl and 46. 98 mg/dl, respectively.
Cholesterol, HDL*
;
Female
;
Humans
;
Male
;
Middle Aged
;
Psoriasis*
8.A study on the effect of PDGF(platelet-derived growth factor) on wound healing.
Ji Young SONG ; Sung Pyo HONG ; Doo Hyung LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(5):802-812
No abstract available.
Wound Healing*
;
Wounds and Injuries*
9.Full-thickness skin graft using the skin stretched by tissue expander.
Young Geun CHO ; Sung Pyo HONG ; Doo Hyung LEE
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1991;18(4):669-675
No abstract available.
Skin*
;
Tissue Expansion Devices*
;
Transplants*
10.Effects of pH Differences on the Skin Moisturizing Capacity of Natural Moisturzing Factors.
Hyung Chan PYO ; Hong Jig KIM ; Young Keun KIM
Korean Journal of Dermatology 1988;26(1):10-16
The flexibility of surface layer of skin is largely dependent upon the layer's water content. This, in turn, depends primarily on the quantity of water soluble hygroscopic and surface active msterials within the straturn corneum, often known as the natural moisturizing fsctors(NMF). It consist of amino acid, lactic acid, pyrrolidone carboxylic acid and inorganic salts etc.. Some of these components are greatly influenced by hydrogen ion content and ionic form of them were found to be highly hygroscopic. In this experiment, sunburn exfoliated human stratum corneum and pig epidermis separated by 2N-NaBr were used as in vitro test. These tissues were so treated to hsve each pH value (3, 5, 7, 9) and their water holding capacity and hygroscopicity were measured by gravimetric method. The results are summarized as follows : 1, Water holding capactiy of sunburn exfoliated human skin showed significant increase at pH 5 (p<0.1), 7 (p<0.01), 9 (p<0.01) compared to pH 3, and increase in pH 7 (p<0.1), 9 (p<0.05) compared to pH 5 in lactic acid. In pig epidermis, there was significant increase at pH 5 (p<0.05), 7 (p<0.01), 9 (p<0.05) cornpared to pH 3 in lactic acid. 2. Hygroscopicity of pig epidermis showed significant increase at pH 5 (p<0.05), 7 (p<0.1), 9 (p<0.05) in lactic acid and at pH 5
Epidermis ; Humans ; Hydrogen-Ion Concentration* ; Lactic Acid ; Pliability ; Protons ; Salts ; Skin* ; Sunburn ; Water ; Wettability