No abstract available.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*

Diffuse neonatal hemangiomatosis is an uncommon disease that is characteristed by a diffuse nature of the lesions, and distinguished form a single or few, or superficial or deep, capillary, cavernous, or mixed hemangiomas occuring in early or adult life. We report an autopsy case of multiple hemangiomatosis, which is associated with massive osteolysis of right humerus and arteriovenous fistulae in surrounding soft tissues. The patient is a 23 day old female infant and had a 2.0x1.5 cm sized cystic destructive bony lesion which was located in the proximal shaft of right humerus. Right arm was hypertrophied, compared to the normal looking left. There were multiple hemangiomas in right humerus, lung, cutaneous skeletal muscles and nerves. This case shares clinical characteristics of Gorham's disease.
Infant ; Adult ; Male ; Female ; Infant, Newborn ; Humans ; Hemangioma

This investigation was undertaken to evaluate the natural and modified course of postoperative astigmatism, and to determine the stabilization time of refraction following extracapsular cataract extraction with posterior chamber IOL implantation. Among the patients who underwent extracapsular cataract extraction with posterior chamber IOL implantation performed by one surgeon(Kim) between April 1987 and August 1987, 46 patients who could be followed up over 6 months were included. The corneoscleral incision was closed with 7 to 8 interrupted 10/0 nylon monofilament sutures. In 10 eyes of 46 eyes the sutures were cut with a precut razor fragment under the operating microscope partially 6 weeks after operation or totally cut 2 months after operation. Our analysis demonstrated the following: A. Cases in which the sutures were not cut(36 eyes). 1. The mean initial corneal astigmatism after operation was 6.931 +/- 1.445 diopters. 2. The mean final cylinder after operation was 1.43 +/- 0.458 diopters. 3. There was no significant relationship between the initial corneal astigmatism and the amount of final cylinder after operation(correlation coefficient=0.0466). 4. The mean of stabilization time of refraction after operation was 3.083 +/- 1.052 months. 5. The relationship between the initial corneal astigmatism and the time of stabilization of refraction after operation was significant(correlation coefficient=0.3466). B. Cases in which the sutures were cut(10 eyes). 1. In 40% of eyes the pre-and postoperative corneal astigmatism were the same, and in 80% of eyes the change was equal to or less than 0.75 diopters.
Astigmatism* ; Cataract Extraction* ; Cataract* ; Humans ; Nylons ; Sutures

To evaluate the efficacy and immediate complications of Q-switched Nd:YAG laser iridotomy in the treatment of angle closure glaucoma, Q-switched Nd:YAG laser iridotomy using coherent model 7900(U.S.A.)was performed on 50 eyes, 43 patients with angle closure glaucoma between Feb. 1987 and Mar. 1988. Forty-six eyes of Thirty-nine Patients had been followed up {or more than 2 months. Four eyes were lost to follow-up. Among 50 treated eyes, 46 required a single laser session for patency and four eyes required two sessions. Intraocular pressure was significantly decreased after Q-switched Nd: YAG laser iridotomy and the continuous use of previous glaucoma medications as necessary(p<0.01). Immediate postoperative intraocular pressure elevation was seen in two Nd:YAG-treated eyes. Thirty-five eyes treated with the Nd:YAG laser had minimal bleeding from the iridotomy site. Forty-four Nd:YAG-treated eyes had transient iritis.
Glaucoma* ; Glaucoma, Angle-Closure ; Hemorrhage ; Humans ; Intraocular Pressure ; Iritis ; Lasers, Solid-State ; Lost to Follow-Up

PURPOSE: Neonates in neonatal intensive care units(NICU) have a high risk of acquiring nosocomial infection because of their impaired host defence mechanism and invasive procedures. Nosocomial infection result in considerable morbidity and mortality among neonates. This study was carried out to survey both the epidemiology of nosocomial infection in our NICU and the annual trends of pathogens. METHODS: We retrospectively reviewed culture proven nosocomial infection which occurred in our NICU from January 1995 to December 1999. The data included clinical characteristics, site of infection, pathogens, and mortality. RESULTS: Nosocomial infection rates was 9.0 per 100 NICU admissions during the five-year period. Major sites of infection were bloodstream(32.3%), skin(18.4%), endotracheal tube(17.2%), and catheter(10.6%). The most common pathogen was S. aureus(29.9%). and the others were coagulase-negative staphylococci(CONS)(14.8%), Enterobacter(12.4%), and Candida(9.0%). During the five-year period, nosocomial infection rates increased from 9.5 to 11.6 per 100 admissions with the increase of CONS, Candida, Klebsiella, and Acinetobacter baumannii. The infection rate of S. aureus decreased. Multiple episodes of nosocomial infection occurred in 26.1% of all nosocomial infections. Overall bloodstream infection rates were 3.6 per 100 NICU admissions during five years. CONS(29.1%) and S. aureus(27.1%) were the two most common pathogens. Increasing rates of bloodstream infection by CONS, Candida, Klebsiella, and Acinetobacter baumannii were observed. Bloodstream infection related mortality was 11.9%. CONCLUSION: The predominant pathogens of nosocomial infection in NICU were S. aureus and CONS. Bloodstream infection, the most frequent nosocomial infection, should be a major focus of surveillance and prevention efforts in NICU.
Acinetobacter baumannii ; Candida ; Cross Infection* ; Epidemiology ; Humans ; Infant, Newborn ; Intensive Care, Neonatal* ; Klebsiella ; Mortality ; Retrospective Studies

BACKGROUND: The current techniques for percutaneous coronary interventions (PCI) remain limited by restenosis. Recent studies have provided evidence of inflammation playing a role in the pathogenesis of cardiovascular disease. METHODS: Whether inflammatory markers are predictors of subsequent restenosis were prospectively tested in 272 consecutive patients with angiographically proven coronary artery disease. Patients having undergone PCI at Chonnam National University Hospital, between Sept. 1999 and Mar. 2001, were divided into two groups according to the occurrence of restenosis on a follow-up coronary angiogram: Group I were patients with restenosis (n=99, 59.5 +/- 10.8 years, M: F=77: 22) and Group II were those without restenosis (n=173, 58.8 +/- 10.2 years, M: F=131: 42). The IgG seropositivity, cytomegalovirus (CMV) titers, C. pneumoniae, H. pylori and levels of C-reactive protein (CRP) were compared between the two groups. RESULTS: There were no statistical differences in the seropositivity of the CMV IgG C. pneumoniae IgG and H. pylori IgG between the two groups (Groups I vs. II: 100 vs. 100%, 24.7 vs. 25.7% and 62.2 vs. 63.7%, respectively). Of the angiographic parameters, a low Thrombolysis In Myocardial Infarction (TIMI) flow (TIMI 0 or I) was more common in Group I than Group II (p=0.038). The patients with an elevated CRP (> 0.5 mg/dL) were more common in Group I than Group II (57.6 vs. 36.4%, p=0.001), with the CRP values being higher in Group I than Group II (3.3 +/- 5.8 vs. 1.3 +/- 2.6 mg/dL, p=0.001). According to a multiple logistic regression analysis, the CRP was the only predictor of restenosis, with an odds ratio of 2.1169 (95% C.I. 1.2062-3.7154, p=0.009). CONCLUSION: The CRP value is the most important predictor of restenosis after PCI.
*Angioplasty, Transluminal, Percutaneous Coronary ; Antibodies, Bacterial/blood ; Antibodies, Viral/blood ; Biological Markers/analysis ; C-Reactive Protein/*analysis ; Chlamydophila pneumoniae/immunology ; Comparative Study ; Coronary Angiography ; Coronary Restenosis/*blood/diagnosis/*therapy ; Cytomegalovirus/immunology ; Female ; Helicobacter pylori/immunology ; Human ; Male ; Middle Aged ; Predictive Value of Tests ; Prognosis ; Prospective Studies ; Recurrence

BACKGROUND: Current techniques of percutaneous coronary interventions (PCI) remain limited by the restenosis. Recent studies provide evidence that inflammation plays a role in the pathogenesis of cardiovascular disease. METHODS: We prospectively tested whether inflammatory markers are predictors of subsequent restenosis in 272 consecutive patients with angiographically proved coronary artery disease. The patients who underwent PCI at Chonnam National University Hospital between Sep. 1999 and Mar. 2001 were divided into two groups according to the occurrence of restenosis on follow-up coronary angiogram: patients with restenosis (Group I : n=99, 59.5 10.8 years, M : F=77:22) and patients without restenosis (Group II : n=173, 58.8 10.2 years, M : F=131:42). IgG seropositivity and titer of CMV, C. pneumoniae, H. pylori, levels of C-reactive protein (CRP) were compared between two groups. RESULTS: There were no statistical differences in the seropositivity of CMV IgG, C. pneumoniae IgG, H. pylori IgG between two groups (Group I vs. II : 100% vs. 100%, 24.7% vs. 25.7%, 62.2% vs. 63.7% in group I vs. II respectively). Among angiographic parameters, low TIMI flow (TIMI 0 or I) was more common in Group I than in Group II (p=0.038). The patients with elevated CRP (>0.5 mg/dL) were more common in Group I than those in Group II (57.6% vs. 36.4%, p=0.001) and the value of CRP was higher in Group I than in Group II (3.3+/-5.8 mg/dL vs. 1.3+/-2.6 mg/dL, p=0.001). According to multiple logistic regression analysis, CRP was the only predictor of restenosis with odd ratio of 2.1169 (95% C.I. 1.2062-3.7154, p=0.009). CONCLUSION: The value of CRP is the most important predictor of restenosis after PCI.
C-Reactive Protein* ; Cardiovascular Diseases ; Coronary Artery Disease ; Follow-Up Studies ; Humans ; Immunoglobulin G ; Inflammation ; Jeollanam-do ; Logistic Models ; Percutaneous Coronary Intervention* ; Pneumonia ; Prospective Studies