No abstract available.

No abstract available.
Femur*

No abstract available.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*

This investigation was undertaken to evaluate the natural and modified course of postoperative astigmatism, and to determine the stabilization time of refraction following extracapsular cataract extraction with posterior chamber IOL implantation. Among the patients who underwent extracapsular cataract extraction with posterior chamber IOL implantation performed by one surgeon(Kim) between April 1987 and August 1987, 46 patients who could be followed up over 6 months were included. The corneoscleral incision was closed with 7 to 8 interrupted 10/0 nylon monofilament sutures. In 10 eyes of 46 eyes the sutures were cut with a precut razor fragment under the operating microscope partially 6 weeks after operation or totally cut 2 months after operation. Our analysis demonstrated the following: A. Cases in which the sutures were not cut(36 eyes). 1. The mean initial corneal astigmatism after operation was 6.931 +/- 1.445 diopters. 2. The mean final cylinder after operation was 1.43 +/- 0.458 diopters. 3. There was no significant relationship between the initial corneal astigmatism and the amount of final cylinder after operation(correlation coefficient=0.0466). 4. The mean of stabilization time of refraction after operation was 3.083 +/- 1.052 months. 5. The relationship between the initial corneal astigmatism and the time of stabilization of refraction after operation was significant(correlation coefficient=0.3466). B. Cases in which the sutures were cut(10 eyes). 1. In 40% of eyes the pre-and postoperative corneal astigmatism were the same, and in 80% of eyes the change was equal to or less than 0.75 diopters.
Astigmatism* ; Cataract Extraction* ; Cataract* ; Humans ; Nylons ; Sutures

To evaluate the efficacy and immediate complications of Q-switched Nd:YAG laser iridotomy in the treatment of angle closure glaucoma, Q-switched Nd:YAG laser iridotomy using coherent model 7900(U.S.A.)was performed on 50 eyes, 43 patients with angle closure glaucoma between Feb. 1987 and Mar. 1988. Forty-six eyes of Thirty-nine Patients had been followed up {or more than 2 months. Four eyes were lost to follow-up. Among 50 treated eyes, 46 required a single laser session for patency and four eyes required two sessions. Intraocular pressure was significantly decreased after Q-switched Nd: YAG laser iridotomy and the continuous use of previous glaucoma medications as necessary(p<0.01). Immediate postoperative intraocular pressure elevation was seen in two Nd:YAG-treated eyes. Thirty-five eyes treated with the Nd:YAG laser had minimal bleeding from the iridotomy site. Forty-four Nd:YAG-treated eyes had transient iritis.
Glaucoma* ; Glaucoma, Angle-Closure ; Hemorrhage ; Humans ; Intraocular Pressure ; Iritis ; Lasers, Solid-State ; Lost to Follow-Up

BACKGROUND: In most brain operations, the endotracheal tube is kept in postoperatively for airway maintenance during radiologic examinations. But the endotracheal tube causes tracheal irritation and hemodynamic changes. Inhalation anesthetics can not be administered during transport, and minimal concentration is exhaled for several hours after the end of inhalation. The present study was designed : (1) to determine the end tidal isoflurane concentration after the end of administration ; (2) to investigate the effects of intravenous anesthetics in patients with tracheal intubation during radiologic examination postoperatively. METHODS: We selected forty adult patients who were scheduled for elective neurosurgical operation with postoperative brain CT (computerized tomography). The study was performed in 2 steps; in the step 1 (n = 10), end tidal isoflurane concentration was checked after ending inhalation. In the step 2 (n = 30), patients were divided into one of three groups according to anesthesia method; group I (using isoflurane), group P (change from isoflurane to propofol about an hour before operation end), group M (using midazolam instead of propofol, compared to group P). In each group, the frequency of bucking and incidence of hypertension were checked during postoperative radiologic examinations. RESULTS: Minimal concentrations of isoflurane were detected in exhaled gas for about 2 hours after the end of isoflurane inhalation. The frequency of bucking was significantly lower in the group P and M than in group I (P = 0.002). In group P, the incidence of hypertension was significantly reduced compared to group M and I (P = 0.031). CONCLUSIONS: These results suggest that the change of anesthetic technique (from inhalation to intravenous) in the late period of operation, provides postoperative hemodynamic stability, a more comfortable state and minimal environmental pollution in comparison to inhalation anesthesia only.
Adult ; Anesthesia ; Anesthesia, Inhalation ; Anesthesia, Intravenous* ; Anesthetics, Inhalation ; Anesthetics, Intravenous ; Brain ; Environmental Pollution ; Hemodynamics ; Humans ; Hypertension ; Incidence ; Inhalation ; Intubation ; Isoflurane ; Midazolam ; Propofol

BACKGROUND: In most brain operations, the endotracheal tube is kept in postoperatively for airway maintenance during radiologic examinations. But the endotracheal tube causes tracheal irritation and hemodynamic changes. Inhalation anesthetics can not be administered during transport, and minimal concentration is exhaled for several hours after the end of inhalation. The present study was designed : (1) to determine the end tidal isoflurane concentration after the end of administration ; (2) to investigate the effects of intravenous anesthetics in patients with tracheal intubation during radiologic examination postoperatively. METHODS: We selected forty adult patients who were scheduled for elective neurosurgical operation with postoperative brain CT (computerized tomography). The study was performed in 2 steps; in the step 1 (n = 10), end tidal isoflurane concentration was checked after ending inhalation. In the step 2 (n = 30), patients were divided into one of three groups according to anesthesia method; group I (using isoflurane), group P (change from isoflurane to propofol about an hour before operation end), group M (using midazolam instead of propofol, compared to group P). In each group, the frequency of bucking and incidence of hypertension were checked during postoperative radiologic examinations. RESULTS: Minimal concentrations of isoflurane were detected in exhaled gas for about 2 hours after the end of isoflurane inhalation. The frequency of bucking was significantly lower in the group P and M than in group I (P = 0.002). In group P, the incidence of hypertension was significantly reduced compared to group M and I (P = 0.031). CONCLUSIONS: These results suggest that the change of anesthetic technique (from inhalation to intravenous) in the late period of operation, provides postoperative hemodynamic stability, a more comfortable state and minimal environmental pollution in comparison to inhalation anesthesia only.
Adult ; Anesthesia ; Anesthesia, Inhalation ; Anesthesia, Intravenous* ; Anesthetics, Inhalation ; Anesthetics, Intravenous ; Brain ; Environmental Pollution ; Hemodynamics ; Humans ; Hypertension ; Incidence ; Inhalation ; Intubation ; Isoflurane ; Midazolam ; Propofol

To get the pure clinical results of Yag Laser Posterior Capsulotomy, excluding all the possible factors that might affect the results of that, we performed posterior capsulotomies on after cataracts(118 eyes) by using Q-switched Nd:Yag laser from February 1987 to August 1989 and reviewed the results. Group A is composed of 68 surgical aphakic eyes and group B is composed of 50 Posterior chamber pseudophakic eyes. The results were as follows: 1. One eye in groupA and one eye in group B were congenital cataracts and the others were all adult and senile cataracts. 2. As a result of posterior capsulotomy, 59 eyes(86.8%) in group A and 42(84%) in group B were above 0.5 in corrected visual acuity. 3. On performing, the power setting was under 1.5mJ in 59 eyes(86.8%) in groupA and 40 eyes(80%) in group B. 4. Ocular complications developed in 35 eyes(51.5%) in group A and 15 eyes(30%) in group B. 5. Good preoperative ocular condition may predict good postoperative clinical results. 6. Less energy and pulses in operation combined with less occurrences of vitrous prolapse in group B might be associated with less development of postoperative complications in group B than in group A.
Adult ; Aphakia* ; Cataract ; Humans ; Lasers, Solid-State ; Posterior Capsulotomy* ; Postoperative Complications ; Prolapse ; Pseudophakia* ; Visual Acuity

Abberations of the p53 gene in 24 primary gastric carcinomas were examined by single-strand conformation polymorphism analysis of polymerase chain reaction products and by immunohistochemical staining with monoclonal antibody. Of these gastric adenocarcinomas, 23 were advanced gastric carcinomas, and 1 was early gastric cancer. Using polymerase chain reaction (PCR) and a single-strand conformation polymorphism migration technique (SSCP), the presence of mutations in exons 4-9 was evaluated. Using the mouse specific anti-human p53 monoclonal antibody, we also looked for overexpression of the p53 protein in tissue sections. In 5 cases shifted bands were reproducibly identified by PCR-SSCP, and all mutations were in exon 4 and 5,6. Thirteen of the tumor samples were positively stained with the monoclonal antibody. In only one of the 5 mutated cases a positive immunostaining was observed, and we couldn't find the any correlation between the mutations detected by PCR-SSCP and immunostaining. The presence of a p53 mutation by PCR-SSCP was associated with lower PCNA labeling index ( mean = 40.8:75.8%). In the cases with overexpression of p53 protein, the pathologic stages were more advanced than without overexpression of p53 protein (p=0.037). The mutation of p53 was not correlated with mutations of other oncogenes such as c-myc and c-Ha ras. Our results in this group of patients suggest that p53 mutations detected by PCR-SSCP should be reevaluated, and p53 mutations detected by immunostaining was more reliable.
Adenocarcinoma ; Animals ; Exons ; Genes, p53* ; Humans ; Mice ; Oncogenes ; Polymerase Chain Reaction* ; Proliferating Cell Nuclear Antigen ; Stomach Neoplasms*

PURPOSE: Steatocystoma multiplex is a rare benign disease that occurred multiply on whole body surface. Many physicians have tried managing steatocystoma in variable methods. However it is hard to define the optimal way to cure steatocystoma. We performed both aspiration and excisional method to study the usefulness of both methods. METHODS: A 28-year-old woman has asymptomatic multiple subcutaneous nodules on whole body. Most lesions were aspirated with 26-guage needled 3cc syringe but large and purulent three nodules were excised. RESULTS: We diagnosed the lesion histologically as steatocystoma multiplex. Aspirated wound healed without scar, excised wound remained scar but esthetically acceptable. Axillary lesion contained so clustered type cysts that was difficult to aspirate whole cyst. Thus additional excisional method was needed. CONCLUSION: There are many practical methods to cure steatocystoma. However, there is no appropriate method to cure it. Therefore we should select different therapeutic method according to anatomical location and cyst size. Especially at subcutaneous fat-rich lesion like axilla and abdomen, it is better to excise the clustered cyst than to aspirate.
Abdomen ; Adult ; Axilla ; Cicatrix ; Female ; Humans ; Steatocystoma Multiplex ; Syringes