A clinical observation was made on the obstruction at the ureteropelvic Juncture of the inpatient in the Department of Urology. Seoul National University Hospital during the period September, 1961 through August, 1968 and the following results were observed. 1. Of 1824 cases hospitalized, 33 cases werehydronephrosis of non-calculous origin. Among the 33 cages 10 were obstruction ofthe ureteropelvic juncture giving a rate of 30.3%. Age distribution ranged from 4to 48 years with average of 26 years. 2. As to the origin of the obstruction, 5 cases were due to aberrant vessel one congenital stricture one fibrous band and one fibrosis, respectively. The causes were unknown in 2 cases. 3. The most common complaints were pain on the involved site in 8 cases. Palpable mass, gastrointestinal trouble and general weakness were found in 6 cases. Loss of weight and pollakisuria were noted in 3 cases. Hypertension. hematuria, fever andedema were found respectively in one case. 4. All cases including two which showed non-function on IVP showed markedly dilated pelvis and marked narrowing ofthe ureteropelvic juncture. 5. Nephrectomy was performed in 5 cases, removal of aberrant vessel in 2, ureteroplasty in one and ureteral dilation with contralateral nephrectomy in 2.
Age Distribution ; Constriction, Pathologic ; Fever ; Fibrosis ; Hematuria ; Humans ; Hypertension ; Inpatients ; Nephrectomy ; Pelvis ; Seoul ; Ureter ; Urology

Idiopathic ureteropelvic junction stricture is not an uncommon disorder with resultant hydronephrosis of affecting kidney, and most frequently encountered in infant and children. Multiple causes of stricture have been identified. Abnormal organization of smooth muscle bundles at the ureteropelvic junction has been reported, and electron microscopy has demonstrated excessive collagen deposition within the intramural stroma. However, the exact cause of obstruction of UPJ stricture is uncertain. We reviewed 23 cases with idiopathic hydronephrosis underwent dismembered pyeloplasty. Examination of strictured segment with light the normal interwoven pattern, were arranged into an abundant outer circular and an inner longitudinal layer in 21 of 23 cases. But muscle thickness was not changed, and collagen was normal in both amount and arrangement. This results suggested that the abnormal muscle arrangement at the ureteropelvic junction might be the cause of the idiopathic stricture.
Child ; Collagen ; Constriction, Pathologic* ; Humans ; Hydronephrosis ; Infant ; Kidney ; Microscopy, Electron ; Muscle, Smooth

Although hypospadias should be repaired before school age, there is no one good method for all hypospadias repair. The surgical goals of hypospadias repair are primarily correction of chordee, formation of urethral tube, and achievement of a meatus near or at the tip of glans penis in order to achieve a functionally and cosmetically acceptable phallus. We reported on 46 patients who underwent hypospadias repair between May, 1972 and April, 1984. In two stage operation, chordectomy was undergone in 30 cases, of which 1 case had complication with incomplete chordee remove. At recent, with artificial erection technique complete chordee remove is possible. In 42 cages of urethroplasty such as MAGPI, flip-flap, Island flap technique by Duckett, modified Crawford method, Belt-Fuqua, and free flap using thigh skin, urethrocutaneous fistula developed in 9 cases, urethral stricture in 2, and keloid in 1.
Female ; Fistula ; Free Tissue Flaps ; Humans ; Hypospadias* ; Keloid ; Male ; Penis ; Skin ; Thigh ; Urethral Stricture

In vitro culture of Toxoplasma gondii in HL-60 cells cnd cell-mediated immunity against Toxoplasma in dimethylsulfoxide(DMSO)-induced HL-60 cells, i.e., differentiation into granulocytes, were pursued. HL-60 cells were treated with various concentrations of DMSO, and 1.3%(v/v) for 3 day incubation was chosen as the optimal condition for differentiation into granulocytes. The degree of differentiation was assayed in physiological and functional aspects in addition to morphological point. When treated with 1.3% DMSO for 3 days, HL-60 cells did not synthesize DNA materials beyond background level, and showed active chemotactic response to chemotactic peptide, formyl-methionyl-leucyl-phenylalanine(FMLP). Morphologically promyelocytes of high nuclear/cytoplasmic(N/C) ratio changed to granulocytes of relatively low N/C ratio. The relationships between HL-60 cells or DMSO-induced HL-60 cells and Toxoplasma were examined after stain with Giemsa and fluorescent dye (acridine orange). HS-60 cells did not show any sign of toxoplasmacidal activity but showed intracellular proliferation of Toxoplasma to form rosette for 72 hr co-culture. In contrast, DMSO-induced HL-60 cells phagocytosed Toxoplasma within 1 hr, and performed a process of intracellular digestion of Toxoplasma thereafter. With the above results, it is suggested that phagosome-lysosome fusion is one of the critical events for the parasitism by Toxoplasma or for susceptibility of host cells. The in vitro culture system of this study has offered a defined condition to study the protozoan parasite-host cell interactions.
parasitology-protozoa ; Toxoplasma gondii ; HL-60 cells ; dimethylsulfoxide ; in vitro culture ; dimethylsulfoxide

PURPOSE: This study was conducted to examine the relationship between job stress and work-related musculoskeletal symptoms of hospital nurses. METHOD: The questionnaires were administered to 290 nurses working in a general hospital located in S city from September 1 to 15, 2008. The data were analysed with descriptive statistics, and logistic regression test by SPSS WIN 14.0. RESULTS: With the NIOSH criteria 1, the musculoskeletal symptoms were prevalent in 66.8% of the subjects. The musculoskeletal symptoms by body parts appeared mostly on leg/foot(40.6%) and followed by shoulder (38.7%), waist(30.3%), neck(23.6%), hand/wrist/ finger(14.0%) and arm/elbow(4.4%). There were statistically significant differences in prevalence rate of musculoskeletal symptoms by age, work department, career and job stress. CONCLUSION: When developing a management program for musculoskeletal symptoms of hospital nurses, it is necessary to fully understand nurses' work considering each hospital's nursing administration system.
Hospitals, General ; Human Body ; Logistic Models ; National Institute for Occupational Safety and Health (U.S.) ; Prevalence ; Surveys and Questionnaires ; Shoulder

We experienced one case of renal arteriovenous fistula that was treated with superselective transcatheter arterial embolization of the renal artery. The patient presented with colicky pain, gross hematuria, and acute urinary retention. At that time, we suspected renal stone because of a radio-opaque density on the right renal area of excretory urography. However, an acoustic shadow could not identified by renal ultrasonogram. When gross hematuria reappeared one week later, selective renal angiography was performed, and arteriovenous fistula was found on the right kidney. We used superselective tanscatheter arterial embolization with a Gelfoam fragment on right arterial branch as the treatment modality.
Acoustics ; Angiography ; Arteriovenous Fistula* ; Abdominal Pain ; Gelatin Sponge, Absorbable ; Hematuria ; Humans ; Kidney ; Renal Artery ; Ultrasonography ; Urinary Retention ; Urography

BACKGROUND: The proliferation of vascular smooth muscle cell(VSMC) is a part of the major pathogenic mechanism for atheroscle- rosis. It has been reported that L-type calcium channel plays a role in the VSMC proliferation in diabetic rats. But there is a little study results about the association between L-type calcium channel and VSMC proliferation by glucose concentrations in culture media. So we examined the association between voltage-dependent L-type calcium channel of VSMCs and the proliferative activity of vascular smooth muscle cells. METHODS: Rat aortic VSMCs were isolated from the aorta of OLETF rat by enzyme method. VSMCs were cultured in various concentrations of glucose(5.5, 25 mM). The VSMCs(1x104 cells in 24-well plates) were incubated in the presence of Bay K 8644 (10-6M) with/without verapamil(10-6M) for 48 hours. Then the proliferation was assessed by MTT(methylthiazole tetrazolium) assay and expression of L-type calcium channel mRNA was measured by RT-PCR. RESULTS: The proliferative ability and the expression of L-type calcium channel of cultured VSMCs were increased dose-dependently by the glucose concentrations(p<0.05). Bay K 8644 enhanced the proliferation of VSMC and verapamil blocked the incremental effects induced by Bay K 8644. CONCLUSION: These results suggest that L-type calcium channel may play a role in VSMC proliferation of OLETF rat.
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester ; Animals ; Aorta ; Calcium Channels, L-Type* ; Cell Proliferation* ; Culture Media ; Glucose* ; Muscle, Smooth, Vascular* ; Rats ; Rats, Inbred OLETF* ; RNA, Messenger* ; Verapamil

Authors review the clinical and histopathologic findings of 41 EIenoch-Schonlein purpur.a patients and attempt, to clarify the association between abnorma] urinary findings and anti-streptolysin 0(ASLO) titer and performed the direct immunofluorescence(',E)II) study on skin lesion to investigate the pathogenetic mechanim of renal involvement. The results were summarized as follows : 1. Ag(, distribution was form 3 month to 63 years and mean age was 18.9 years. male to female ratio was 1.2:1(22 males '. 19 females). 2. In he past history, there were preceding upper respora.tory infections in 25(61:o)patients and drug history in 10(24.3%)patients. 3. (linical manifestations in the order of frequency were as follows : arthralgia (60.9%), hematuria or albuminuria(43.8%), abdominal pain(21.9%), and positive occult: blood test(7.3%)in stool examination. 4. In the laboratory fiindings, leukocytosis was cleveloped in 14.6%, anemia in 2.4%, increased eryttrocyte sec1imentation zate in 12.3% increased ASLG titer in 43.9% of patients, and serum IgG was increased in 4 of 20(20.6)patierits, IgA in 4 of 21(19%)patients, IgM in 1fo 19(5.3o)patients. 5. Because correlation between increased A.LO titer ancl ahnoormal urinary findings wa.s high(x-test, p< 0.0,5), increased ASI,O titer may be inclicator of renal involvement. 6. DIF stuc].y was per formed in 34 patients. All showed positive reactiviy. IgG(17%), IgA(29.4% ), Clq(14.6%), C3(12.2% ), fibrinog.n(82.4%) were deposited around the vessel wall in a granular pattern. 7. There was statistically significant increase in mean serum IgG value in patients with abnormal urinary findings( t test, p < 0.05 ).
Anemia ; Arthralgia ; Female ; Hematuria ; Humans ; Immunoglobulin A ; Immunoglobulin G ; Immunoglobulin M ; Leukocytosis ; Male ; Purpura* ; Purpura, Schoenlein-Henoch ; Skin

No abstract available.
Humans ; Infant, Newborn*

No abstract available.
Prostatitis*