Autoimmune Diseases ; Collagen ; Cyclosporine ; Fibroblasts ; Gingival Hyperplasia ; Gingival Overgrowth ; Graft Rejection ; Humans ; Intercellular Signaling Peptides and Proteins ; Metabolism ; RNA, Messenger ; Tissue Donors ; Tissue Inhibitor of Metalloproteinase-1 ; Transforming Growth Factor beta1

Sinus floor augmentation has been proven an effective treatment procedure to increase bone volume in the posterior edentulous maxilla. Autogenous bone considered to be the best material for reconstructive bone surgery and has been successfully used as a graft material to augment posterior maxilla. However, the collection of autogenous bone required extra risks for morbidity and complaints. So, various bone graft materials included beta-tricalcium phosphate(beta-TCP) has been introduced for replacing the autogenous bone. The objective of this clinical study was to determine the predictability of endosseous implant placed in a maxillary sinus with beta-TCP grafting. We performed sinus elevation with beta-TCP to install the implant in the 10 maxillary cases. The prosthetic procedure was performed 6-9 months after. The implant-prosthetics was checked about 1 year. We checked the implant and measured the maximum bite force to evaluate the function of the implant. There was not observed the specific problem and complication in dental implant and maxillary sinus in the grafted materials. The maximum bite force was 558N in case of natural tooth, 365N in implant without grafting, 318N in implant with beta-TCP grafting. There was no significant difference between with and without sinus grafting on maximum bite force(P>0.05). As though the long term check-up is needed, the grafting of beta-TCP as a osteoconductive materials can expand the volume and induce dense new bone formation in maxillary sinus. So, this short-term results support that beta-TCP can be a suitable material for sinus augmentation.
Bite Force ; Dental Implants ; Maxilla ; Maxillary Sinus ; Osteogenesis ; Sinus Floor Augmentation ; Tooth ; Transplants