A 28-year-old man presented with a 6.0 * 5.0 cm sized ulcer on the anterior chest and widespread copper-red colored maculopapular eruptions. There was no past or family history of syphilis sign or STS. He had been taken imposition of hands twice to treat chronic hepatitis about 4 months prior to presentation. Thereby, the ulcerative lesion on the anterior chest developed as a result of erosive trauma through contact with infected fingernails. The clinical features and serologic tests as well as biopsy findings were consistent with syphilis. Spirochetes were observed under the dark field examination of the anterior chest lesion. On Warthin-Starry staining, spirochetes were identified in the epidermal area of the papular lesion. We report a case of unusual transmission of syphilis.
Adult ; Biopsy ; Hand* ; Hepatitis, Chronic ; Humans ; Nails ; Serologic Tests ; Spirochaetales ; Syphilis* ; Thorax ; Ulcer

We report a case of cutaneous B cell lymphoma in a 68-year-old male who had primarily developed two 2.0 * 2.0 * 0,6cm sized, dome shaped, dark red colored tumors on the medial side of his left thigh about 4 months previously. His general condition was good and laboratory results were within normal limits, except for the enlargement of aortocaval, paraaortic and left inguinal lymph nodes. Histopathological examinations revealed diffuse dense infiltration of large atypical cells with vesicular nuclei and large prominent nucleoli in the entire dermis. They were largely composed of centroblast and immunoblast-like cells and showed positive reactions to the leukocyte common antigen, and L26 and CD22 was related to peripheral B-cell lineage in the immunohistochemical study. The skin lesions improved completely with an m-BACOD regimen. There was no relapse over a 3-year follow-up period.
Aged ; Antigens, CD45 ; B-Lymphocytes ; Dermis ; Follow-Up Studies ; Humans ; Lymph Nodes ; Lymphoma, B-Cell* ; Male ; Recurrence ; Skin ; Thigh

Nevus sebaceus is a common hamartoma that has a variety of appendage tumors. We report a case of nevus sebaceus with multiple appendage tumors on the scalp of a 43-year-old male. The exudative inflamed patches were admixed with darkly pigmented small nodules which had developed secondarily within a 4.0 × 1.5cm lesion 2 years previously. Histologically, on serial sectioning, there were various types of basal cell carcinoma, syringocystadenoma papilliferum, tubular apocrine adenoma and sebaceous adenoma. Some parts of a biopsy specimen, showed a tumor of the follicular infundibulum-like epidermal changes. There were also calcium depositions in the stroma and apocrine tumors, There was no relapse at 1-year follow-up after surgical treatment.
Adenoma ; Adult ; Biopsy ; Calcium ; Carcinoma, Basal Cell ; Follow-Up Studies ; Hamartoma ; Humans ; Male ; Nevus* ; Recurrence ; Scalp

Verrucous carcinoma of the oral cavity is a rare tumor representing 4.5-9.0% of oral squamous tumors. Involvement of the lip is less common within the oral cavity. It presents as a slowly enlarging, exophytic warty growth with extensive local invasion, though well-differentiated and rarely metastaticl. We herein repart a case of verrucous carcinoma on the lower lip in a 31-year-old man.
Adult ; Carcinoma, Verrucous* ; Humans ; Lip* ; Mouth

Isolated plantar collagenoma with a cerebriform appearance is a hamartomatous lesion consisting of proliferation of normal collagen tissue and has been reported with other systemic alterations described as Proteus syndrome. We report herein a rare case of isolated collagenoma located on the plantar surface with macrodactyly of the 3rd and 4th toes occurring on the right foot, which is considered as an incomplete form of Proteus syndrome. A 36-year-old male with normal intellectual and physical development visited with a pedunculated, soft, dome-shaped tumor and multiple, grouped, slightly elevated nodules on the right plantar region and hypertrophy of the 3rd and 4th toes of the right foot. The lesions appeared during early childhood and have been growing steadily since then. Total excision of the plantar mass with skin grafting and debulking of the 3rd toe and amputation of the 4th toe were done.
Adult ; Amputation ; Collagen ; Foot ; Humans ; Hypertrophy ; Male ; Proteus Syndrome ; Skin Transplantation ; Toes

Secondary cutaneous cryptococcosis may occur earlier than other manifestations of disseminated cryptococcosis. A 68-year-old woman presented with multiple ulcerative lesions on the right calf of 2 weeks duration. She had been treated with antibiotics, but the lesions spread rapidly. The initial clinical impression was necrotizing fasciitis, but routine KOH mounting from the ulcerative lesions showed numerous budding yeast cells with peripheral clear zones and further investigations including a skin biopsy, tissue cultures and India ink preparations allowed a rapid and definitive diagnosis of cutaneous cryptococcosis. Studies for other evidence of infection elsewhere revealed an asymptomatic pulmonary lesion. We report a case of secondary cutaneous cryptococcosis clinically mimicking necrotizing fasciitis that occured before other manifestations of disseminated cryptococcosis.
Aged ; Anti-Bacterial Agents ; Biopsy ; Cryptococcosis* ; Diagnosis ; Fasciitis, Necrotizing* ; Female ; Humans ; India ; Ink ; Saccharomycetales ; Skin ; Ulcer

We report herein a gigantic case of verrucous hemangioma occuring in a 15 year-old school- boy. The lesion was a dark red colored, 10.0 x 6.0 x 0.8cm sized, verrucous surfaced, hemangiomatous tumor affecting the posterior aspect of the right thigh. At birth an erythematous macule appeared and insidious]y increased or extended with age. In the last 6 months, it had grown rapidly to the size of the present lesion with a smaller satellite one, assumably ascribing to the repeated minor trauma or pressure. Histological findings from the totally excised lesion showed epidermal hyperplasia with irregular acanthosis and papillomatosis and diffuse marked proliferation and dilatation of blood vessels from the upper dermis to subcutaneous fatty tissue. Wide excision was done. There was no relapse after about one years postoperative follow up.
Adipose Tissue ; Adolescent ; Blood Vessels ; Dermis ; Dilatation ; Follow-Up Studies ; Hemangioma* ; Humans ; Hyperplasia ; Male ; Papilloma ; Parturition ; Recurrence ; Thigh

We have encountered a rare case of erythema nodosum-like leukemia cutis associated with acute myelocytic leukemia(AML) in a 57-year-old male. He was in good health until about 2 weeks prior to admission, when the systemic symptoms of high fever, anorexia, general weakness and malaise, and subcutaneous nodules developed. The nodules were multiple, red and noted bilaterally on the pretibial areas. Histological findings of his skin lesions showed diffuse cellular infiltrates intermingled with leukemic cells predominantly involving the adipose tissues. The cells displayed negative stainirig to antibodies CD3 and CD20, but positive staining to LCA. The diagnosis of AML(M4) was made by blood and bone marrow studies. He had a rapid downhill course and was discharged after 2 weeks of admission, with no anti-cancer chemotherapy.
Anorexia ; Antibodies ; Bone Marrow ; Diagnosis ; Drug Therapy ; Erythema* ; Fever ; Humans ; Leukemia* ; Leukemia, Myeloid, Acute ; Male ; Middle Aged ; Skin

No abstract available.
Brachial Plexus* ; Golf*

Takayasu's arteritis is an arteritis of undetermined etiology, which affects the aorta and the proximal portions of its major branches. But aortic regurgitation and coronary artery involvement were unusual manifestations in this disease. We experienced a patient of Takayasu's arteritis who represented these unusual manifestations. Aortogram revealed grade IV aortic regurgitation and proximal segment narrowing of left main coronary artery. A case of Takayasu's arteritis associated with aortic regurgitation and left main coronary artery involvement is reported with a review of literatures.
Aorta ; Aortic Valve Insufficiency* ; Arteritis ; Coronary Vessels* ; Humans ; Takayasu Arteritis*