1.Cryoanalgesia for the postthoracotomy pain.
Oug Jin KIM ; Young Ho CHOI ; Hyoung Mook KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(1):54-63
No abstract available.
2.Clinical and Statistical Observations of Bleeding Disorders in Childhood.
Ha Young LEE ; Chong Sung CHUNG ; Kyu Chul CHOI ; Yong Mook CHOI ; Chang Il AHN
Journal of the Korean Pediatric Society 1988;31(2):186-195
No abstract available.
Hemorrhage*
3.A Case of Doxorubicin-induced Dilated Cardiomyopathy.
Sang Young JEONG ; Soo Chun KIM ; Sung Ho CHA ; Young Mook CHOI ; Chang Il AHN
Journal of the Korean Pediatric Society 1989;32(8):1132-1137
No abstract available.
Cardiomyopathy, Dilated*
4.Clinical Significance of Axillary Lymph Nodes a Observed in Mediolateral Oblique View of IVlammography.
Ik YANG ; Yul LEE ; Soo Young CHUNG ; Bo Whan CHOI ; Young Mook KIRN ; Il Sung LEE
Journal of the Korean Radiological Society 1995;32(1):181-184
PURPOSE: To evaluate the radiologic characteristics of axillary lymph nodes which are found on mediolateral oblique(MLO) view of mammography and to assess their clinical significance. MATERIALS AND METHODS: We retrospectively evaluated 119 cases axillary lymph nodes on MLO view of 410 cases of mammography in 205 patients regarding the size, bilaterality, number, grade of density, presence of central lucency, calcification of lymph nodes and presence of associated parenchymal pathologic lesions in breast. RESULTS: Axillary lymph nodes on MLO view were demonstrated in 119 (29%) among 410 cases. Axillary lymph nodes(112 cases) in cases without breast parenchymal lesions or with benign breast lesions showed; unilaterality in 68 cases(61%), smaller than 1.5cm in 100 cases(89%), lower density than breast parenchyma in 99 cases(88%), presence of central lucency in 99 cases(88%) and calcification in 3 cases(2.7%). Axillary lymph nodes(7 cases)in cases with breast cancer showed small size of less than 1.5cm in 4 cases(57%), absence of central lucency in 7 cases(100%) and iso-to higher density than breast parenchyma in 7 c&ses(100%). CONCLUSION: Axillary lymph nodes noted on MLO view of mammography, more than 1.5cm in diameter, absence of central lucency and iso to higher density than breast parenchyma could be suggested as clinically significant.
Breast
;
Breast Neoplasms
;
Humans
;
Lymph Nodes*
;
Mammography
;
Retrospective Studies
5.Clinical Significance of Axillary Lymph Nodes a Observed in Mediolateral Oblique View of IVlammography.
Ik YANG ; Yul LEE ; Soo Young CHUNG ; Bo Whan CHOI ; Young Mook KIRN ; Il Sung LEE
Journal of the Korean Radiological Society 1995;32(1):181-184
PURPOSE: To evaluate the radiologic characteristics of axillary lymph nodes which are found on mediolateral oblique(MLO) view of mammography and to assess their clinical significance. MATERIALS AND METHODS: We retrospectively evaluated 119 cases axillary lymph nodes on MLO view of 410 cases of mammography in 205 patients regarding the size, bilaterality, number, grade of density, presence of central lucency, calcification of lymph nodes and presence of associated parenchymal pathologic lesions in breast. RESULTS: Axillary lymph nodes on MLO view were demonstrated in 119 (29%) among 410 cases. Axillary lymph nodes(112 cases) in cases without breast parenchymal lesions or with benign breast lesions showed; unilaterality in 68 cases(61%), smaller than 1.5cm in 100 cases(89%), lower density than breast parenchyma in 99 cases(88%), presence of central lucency in 99 cases(88%) and calcification in 3 cases(2.7%). Axillary lymph nodes(7 cases)in cases with breast cancer showed small size of less than 1.5cm in 4 cases(57%), absence of central lucency in 7 cases(100%) and iso-to higher density than breast parenchyma in 7 c&ses(100%). CONCLUSION: Axillary lymph nodes noted on MLO view of mammography, more than 1.5cm in diameter, absence of central lucency and iso to higher density than breast parenchyma could be suggested as clinically significant.
Breast
;
Breast Neoplasms
;
Humans
;
Lymph Nodes*
;
Mammography
;
Retrospective Studies
6.Clinical Observation on Antihypertensive Effects of Diltiazem Hydrochloride(Herben(R)).
Young Jung KIM ; Myoung Mook LEE ; Yun Shik CHOI ; Jung Don SEO ; Young Woo LEE
Korean Circulation Journal 1985;15(1):119-124
The antihypertensive effects of diltiazem was observed in 30 cases of essential hypertension, and following results were obtained. 1) Mean decrease in systolic and diastolic blood pressure by oral diltiazem was 42.0+/-2.5mmHg and 17.8+/-1.7mmHg. The results of antihypertensive therapy revealed good control in 50% fair control in 30% poor in 17% and failure in 3% of the cases. In 80% of the cases, good or fair control of Hypertension which means drop of diastolic pressure to the level of less than 100mmhg was observed. 2) Mean drop in heart rate was 21+/-2 beats/min. 3) Daily dose was 90-180mg. 4) The side effect of oral Diltiazem was mild headache and dizziness, respectively one case.
Blood Pressure
;
Diltiazem*
;
Dizziness
;
Headache
;
Heart Rate
;
Hypertension
7.Clinical Cardiac Electrophysiological Study on the Sinus Node and Atrioventricular Conduction System.
Yun Shik CHOI ; Myoung Mook LEE ; Young Bae PARK ; Jung Don SEO ; Young Woo LEE
Korean Circulation Journal 1985;15(2):255-268
Clinical EPS was performed in 16 normal adults without evidence of conduction disease on the surface standard 12 lead electrocardiogram in order to provide normal electrophysiological values of the sinus node function and AV conduction. EPS was also performed in 15 patients with sick sinus syndrome and 10 patients with AV conduction disturbance to evaluate the clinical usefulness of EPS in detecting sinus node dysfunction and AV conduction disturbance. The results were as follows. 1) The results of sinus node function test in the normal group were m-SNRT 853+/-198msec(range 800-1,560msec), c-SNRT 230+/-66msec(range 120-370msec), and %m -SNRT/SCL 127+/-11%(range 114-149%). 2) In 15 patients with SSS, the M-SNRT were ranged from 1,270 to 12,330msec and 10 patients(66%) had significantly increased m-SNRT exceeding 1,560msec. The c-SNRT were ranged from 230 to 10,730msec and 13 patients(83%) had significantly increased c-SNRT exceeding 370msec. The % m-SNRT/SCL were ranged from 136 to 770% and 12 patients(80%) had significantly increased % m-SNRT/SCL exceeding 150%. 3) The SACT in normal group were 84+/-14msec(range 70-105msec) measured by continuous atrial pacing method and 80+/-19 msec(range 60-115msec) measured by atrial extrastimulation method. 4) In SSS, the SACT measured by continuous atrial pacing method was ranged from 80 to 1,050msec and 11/12 patients(92%) had significantly increased SACT exceeding 112 msec. The SACT measured by atrial extrastimulation method was ranged from 90 to 310msec and 7/8 patients(88%) had significantly increased SACT exceeding 118 msec. 5) C-SNRT, % m-SNRT/SCL, and SACT were more useful in detecting sinus node dysfunction than m-SNRT. 6) The AV conduction intervals in normal group were PA interval 17+/-6(range 5-25msec), AH interval 96+/-18 msec(range 70-135msec), and HV interval 46+/-7msec(range 35-55msec). 7) Rapid atrial pacing induced Wenckebach type second degree AV block proximal to H at pacing rate of 90 to 190/min in 14/16 normal adults. 2 patients maintained intact AV conduction upto maximum pacing rate of 200/min. 8) His bundle electrogram showed the site of AV block in 9 of 10 patients with AV conduction disturbances. The sites of AV block were AV nodal area 1 case, intraHis bundle 4 cases, and infraHis bundle 4 cases. 9) EPS provided a good supportive information that was useful in selecting pacemaker therapy in a patient with chronic bifascicular block who revealed prolonged HV interval and infraHis bundle block at a pacing rate of 70min. 10) The refractory periods of AV conduction system in normal group were AERP 274+/-54msec (range 170-410msec), AVN-FRp 467+/-74msec(range 285-600msec), AVN-ERP 341+76msec(range 190-460), and V-ERP 280+/-25msec(range 240-320msec).
Adult
;
Atrioventricular Block
;
Electrocardiography
;
Electrophysiologic Techniques, Cardiac
;
Humans
;
Sick Sinus Syndrome
;
Sinoatrial Node*
8.Maintenance Therapy with Activated Prothrombin Complex Concentrate (aPCC) for Hemophilia Patients with High Levels of Responding Inhibitors.
Ki Young YOO ; Yong Mook CHOI ; Young Shil PARK
Korean Journal of Hematology 2009;44(4):205-211
BACKGROUND: Eleven percent of severe hemophilia A patients and 5% of severe hemophilia B patients may develop inhibitors. We have conducted aPCC-based maintenance therapy for hemophilia patients with high levels of responding inhibitors and we analyzed the efficacy, safety, the factor consumption and the expense of this treatment, as compared to on-demand therapy. METHODS: Eleven hemophilia patients with high levels of responding inhibitors were eligible for the study. We tried to evaluate the longitudinal bleeding episodes, the inhibitor titers, the X-ray findings, the adverse events and the factor consumption between on-demand therapy and maintenance therapy. The bypassing agent in this study was aPCC having a longer half-life. The dosage was 30~50 U/kg, 3 times a week. RESULTS: The mean follow-up period was 6.8 months for on-demand therapy and 10.6 months for maintenance therapy. The mean dosage of aPCC was 45.2 U/kg. The episodes of hemarthrosis decreased by 61.4% (P=0.003) and other significant bleedings decreased by 45.2% (P=0.109). The inhibitor titers decreased in 7 patients and these increased in 4 patients, but anamnesis took place in only 1 patient. Radiologically, 2 patients improved, 1 patient got worse and 7 patients were stable. Neither adverse signs nor symptoms were noticed. The mean factor consumption changed from 55.8x10(3) U for aPCC and 48.6 mg for rFVIIa on-demand therapy to 216x10(3) U for aPCC and 4.8 mg rFVIIa for maintenance therapy. Maintenance therapy cost 67% more than on-demand therapy monthly (P=0.041). CONCLUSION: aPCC-based maintenance therapy for hemophilia patients with high responding inhibitors cost 67% more than on-demand therapy, but it reduced by 61.4% the episodes of hemarthrosis and 45.2% of the other significant bleedings. aPCC-based maintenance therapy can very effectively reduce the bleeding episodes of hemophilia patients with high levels of responding inhibitors.
Factor VIIa
;
Follow-Up Studies
;
Half-Life
;
Hemarthrosis
;
Hemophilia A
;
Hemophilia B
;
Hemorrhage
;
Humans
;
Hypogonadism
;
Mitochondrial Diseases
;
Ophthalmoplegia
;
Prothrombin
;
Recombinant Proteins
9.Upper Gastrointestinal Fiberoptic Endoscopy in Children.
Dong Hyup LEE ; Chong Woo BAE ; Yong Mook CHOI ; Chang Il AHN ; Young Il MIN
Journal of the Korean Pediatric Society 1987;30(8):868-873
No abstract available.
Child*
;
Endoscopy*
;
Humans
10.Clinical Observation on Antihypertensive Effects of Atenolol(Tenormin(R)).
Myoung Mook LEE ; Yun Shik CHOI ; Jungdon SEO ; Young Woo LEE
Korean Circulation Journal 1981;11(2):139-143
The antihypertensive effects of once-daily 50mg dose of atenolol(Tenormin(R)) were observed in 28 cases of essential hypertension, and the results were as follows. 1. Mean drop in systolic and diastolic pressure were 19mmHg and 16mmHg respectively. 2. In 85.7% of the cases good or fair control of blood pressure was resulted. 3. Transient indigestion and fatigue were complained by 3 patients, but subsided spontaneously with continuous treament.
Blood Pressure
;
Dyspepsia
;
Fatigue
;
Humans
;
Hypertension