A case of established infected nonunion of femur after open reduction and internal fixation of proximal femoral fracture with plate and screws in a 20-year-old man has been satisfactorily treated with a conventional Kiintscher nail filled with antibiotic laden bone cement in its hollow cavity. Though the removal of plate and screws, wound debridement, insertion of antibiotic laden bone cement bead at the nonunion site with temporary external skeletal fixation and skeletal traction preceded, a rigid fixation by the nail and vancomycin elution from the cement are believed to have contributed for bony union without troublesome complication of infection in this case.
Debridement ; Femoral Fractures ; Femur* ; Fracture Fixation ; Humans ; Traction ; Vancomycin ; Wounds and Injuries ; Young Adult

No abstract available.
Cytomegalovirus Infections* ; Cytomegalovirus*

No abstract available.

We report an autopsy case of secondary hemochromatosis associated with multiple frequent blood transfusion for the treatment of aplastic anemia. A 23-year-old man had been diagnosed as having aplastic anemia at the age of 13. He received a whole blood transfusion, about 1280 ml, every month during the past 10 years. Recently he developed diabetes mellitus and a congestive heart failure. The autopsy revealed that multiple organs were affected by secondary hemochromatosis, including the liver, heart, pancreas, spleen, bone marrow, stomach, thyroid gland, adrenal glands, and testes. The lungs and liver showed gross and microscopic findings consistent with a congestive heart failure in addition to hemochromatosis. The details are presented. This is a case of rare secondary hemochromatosis occurring in a young man and presenting the classic histopathologic changes indistinguishable from those of primary hemochromatosis.
Adrenal Glands ; Anemia ; Anemia, Aplastic* ; Autopsy* ; Blood Transfusion ; Bone Marrow ; Diabetes Mellitus ; Heart ; Heart Failure ; Hemochromatosis* ; Humans ; Liver ; Lung ; Pancreas ; Spleen ; Stomach ; Testis ; Thyroid Gland ; Young Adult

No abstract available.
Bronchi*

To evaluate the degree of competitive exclusion against Salmonella gallinarum(S. gallinarum) of Salmonella enteritidis(S. enteritidis) infected chickens, fifty-six, 4-week old Hyline layer suspected of S. enteritidis infection were challenged with S. gallinarum. All chickens were tested for S. enteritidis isolation using cloacal swabs and serum plate agglutination test using S. enteritidis Ag. before challenge and classified into four groups(SE isolated, SE nonisolated, SE seropositive and SE seronegative). None of the SE isolated and the SE seropositive groups died after challenge and the average weight gains were 245.5g and 254.6g, respectively. But in the SE nonisolated and the SE seronegative groups, mortality was 18.2% and 20.6% and the average weight gains were 150.1g and 111.2g. The incidence of reisolation of S. gallinarum of the SE isolated and the SE seropositive groups were 41.7% and 47.6% from liver, 33.3% and 47.6% from spleen and 8.3% and 14.3% from cecum, respectively, and the SE nonisolated and the SE seronegative group were 63.6% and 64.7% from liver, 84.1% and 88.2% from spleen and 47.7% and 52.9% from cecum. The serological response of the SE isolated and the SE seropositive groups hardly changed from 75.0 and 81.8% before challenge to 75.0 and 85.7% after. But, the other two groups were found to be significantly higher after challenge and increased from 0 and 18.2% to 100%. Consequently, S. enteritidis preinfected chickens were found to be significant different in terms of mortality, weight gain, reisolation of S. gallinarum and serological response compared to noninfected chickens. Moreover, our study shows that S. enteritidis infected chickens appear strong competitive exclusion against the colonization of S. gallinarum.
Animals ; Chickens ; Disease Outbreaks/veterinary ; Korea/epidemiology ; Oviposition ; Poultry Diseases/*microbiology ; Salmonella/*classification/*isolation & purification ; Salmonella Infections, Animal/*microbiology ; Salmonella enteritidis/*classification/*isolation & purification ; Serotyping ; Weight Gain

OBJECTIVE: To define the prevalence of thyroid dysfunction and autoantibodies in rheumatoid arthritis(RA). A prospective controlled study was conducted on 62 RA patients and 55 controls with non-inflammatory rheumatic diseases (3 osteoarthritis, 6 fibromyalgia, 4 carpal tunnel syndrome and 42 patients with nonspecific joint pain). All subjects were tested for T3, T4, TSH, FT4, RAIU, rheumatoid factor and ANA. Anti-thyroglobulin (TG) Ab and anti-microsomal (Mic) Ab were assayed using a more sensitive direct assay of RIA and TSH-R Ab (TRAb) using competitive radioimmunoassay. Thyroid dysfunction was observed in 10 RA patients (16.2%) of which 6 patients had hypothyroidism and 4 patients hyperthyroidism, and was significantly more prevalent in RA (p=0.026). Anti-Mic Ab was significantly more prevalent in RA patients. The frequencies of anti-Mic Ab and anti-TG Ab in RA patients were 69.4% and 58.1% (cut-off value was 0.3U/ml), but were 16.1% and 12.9% when those over 10U/ml were calculated. Thyroid dysfunction was not present when either of anti-TG Ab or anti-Mic Ab was below 0.3U/ml. The prevalence of thyroid dysfunction or autoantibodies were not different according to the presence of RF or ANA. CONCLUSION: The prevalence of thyroid dysfunction and autoantibodies were significantly increased in RA patients and the variance of the latter in other reports might be explained at least partially by difference in cut-off values of different methods. Thyroid dysfunction may not develop when either of anti-Mic Ab or anti-TG Ab is below 0.3 U/ml in RA.
Arthritis, Rheumatoid* ; Autoantibodies ; Carpal Tunnel Syndrome ; Fibromyalgia ; Humans ; Hyperthyroidism ; Hypothyroidism ; Joints ; Osteoarthritis ; Prevalence ; Prospective Studies ; Radioimmunoassay ; Rheumatic Diseases ; Rheumatoid Factor ; Thyroid Gland*

Tracheopathia osteoplastica is a rare, benign pathologic condition chahacterized the occurrence of numerous cartilage and bony nodules within the tissue of mucosa. We report a case of tracheopathia osteoplastica that involved both larynx and trachea. The patient was 73 years old male and had hoarseness. The neck CT showed thickened and irregular wall of the trachea extending to the level of the carina with multiple calcified nodules and plaques of bony density projecting into the lumen.
Cartilage ; Hoarseness ; Humans ; Larynx ; Male ; Mucous Membrane ; Neck ; Trachea

BACKGROUND: As atrial fibrillation occurs in the patients with hypertensive heart disease, the functional abnormalities of heart become more severe and the risk of systemic and cerebral embolization increases. In this study we checked left atrial dimension and other parameters with echocardiography in hypertensive patients with atrial fibrillation. METHODS: In an attempt to define the difference in left atrial dimension and the relation between left atrial size and various echocardiographic parameters, M-mode echocardiography was used to study 63 hypertensive patients, 33 patients with atrial fibrillation, and 30 patients with sinus rhythm. RESULTS: The mean left atrial dimension was 51.7±8.7mm in hypertensive patients with atrial fibrillation versus 39.3±8.4mm in hypertensive patients with sinus rhythm(p < 0.001). In hypertensive patients with atrial fibrillation left atrial dimension was over 50mm in 82%(27 of 33). Left atrial size had positive correlations with end-systolic and -diastolic internal dimension of left ventricle(LV), LV mass and E-point septal separation, and negative correlations with fractional shortening and ejection fraction of LV. CONCLUSION: The echocardiographic measurement of left atrial dimension in patients with hypertension was useful in evaluating the hypertensive heart disease.
Atrial Fibrillation ; Echocardiography ; Heart ; Heart Diseases ; Humans ; Hypertension

Malignant transformation of fibrous dysplasia to osteosarcoma is rare. We report a case in which monostotic fibrous dysplasia of the proximal femur treated with curettage, Ender nailing and bone grafting was differentiated into the osteosarcoma in a 58-year-old female.
Bone Transplantation ; Curettage ; Female ; Femur ; Fibrous Dysplasia, Monostotic ; Humans ; Middle Aged ; Osteosarcoma