BACKGROUND: The increase of the incidence of autoimmune diseases and the autoimmune pathogenesis of vitiligo were reported. OBJECTIVE: We studied the frequency of autoimmune disorders and positivity of antinuclear antibody in Korean vitiligo patients. METHODS: Vitiligo patients (439 patients) and control subjects (197 patients) were interviewed about their history of autoimmune diseases. Laboratory studies including complete blood cell count, urine analysis, blood chemistry, fasting blood sugar, thyroid function test (T3, free T4, TSH), and antinuclear antibody were performed for the screening of autoimmune disorders. RESULTS: The diseases associated with vitiligo were microcytic hypochromic anemia (3.64%), non-insulin dependent diabetes mellitus (2.96%), thyroid disease (3.96%), atrophic gastritis, and alopecia areata. In the control subjects, the associated diseases were microcytic hypochromic anemia (1.62%), non-insulin dependent diabetes mellitus (4.65%), and thyroid disease (3.49%). These results show that the frequency of autoimmune disorders in vitiligo patients is not significantly higher than that in control subjects. Six (54.5%) out of 11 vitiligo patients with thyroid disease were diagnosed as having thyroid disease for the first time. Four (0.91%) out of 438 vitiligo patients showed positive to antinuclear antibody. Positivity of antinuclear antibody was not higher in vitiligo patients than that in control subjects (1.16%). CONCLUSION: Frequency of autoimmune diseases and positive reaction to antinuclear antibody in vitiligo patients were not significantly higher than those in control subjects.
Alopecia Areata ; Anemia, Hypochromic ; Antibodies, Antinuclear ; Autoimmune Diseases ; Blood Cell Count ; Blood Glucose ; Chemistry ; Diabetes Mellitus ; Fasting ; Gastritis, Atrophic ; Humans ; Incidence ; Mass Screening ; Thyroid Diseases ; Thyroid Function Tests ; Vitiligo*

INTRODUCTION: In this study, we compared sleep structure, EEG characteristic of pediatric obstructive sleep apnea (OSA) and normal controls which were matched in sex and age. METHODS: Fifteen children (male:female=4:11) who complained snoring and were suspected to have sleep apnea and their age and sex matched normal controls (male:female=5:10) have been done nocturnal polysomnography (NPSG). Sleep parameters, sleep apnea variables and relative spectral components of EEG from NPSG have been compared between both groups. RESULTS: Pediatric OSA group were distinguished from normal controls in terms of apnea index, respiratory disturbance index and nadir of oxyhemoglobulin desaturation. Pediatric OSA group showed increased percent of sleep stage 1, decreased rapid eye movement sleep percent and increased delta power in O1 EEG channel. However other sleep parameters and spectral powers were not different between two groups. CONCLUSION: In pediatric OSA group, sleep structure parameter disruption may be not prominent as the previous studies for adult OSA group because of including mild OSA data in diagnostic criteria. In addition, EEG changes might not be distinct due to low arousal index compared to adult OSA patients. We can observe general characteristics and particularity of pediatric OSA through this study.
Adult ; Apnea ; Arousal ; Child ; Electroencephalography ; Humans ; Polysomnography ; Sleep Apnea Syndromes ; Sleep Apnea, Obstructive ; Sleep Stages ; Sleep, REM ; Snoring

Segmental fracture of the femoral shaft is known as an unusual injury, usually caused by severe force and associated with marked damage to the soft tissue, and is difficult to treat due to these causes it is a controversal topic in regard to the treatment. Authors analysed 14 cases of segmental fracture of the femoral shaft, except cases associated with hip fracture, which had received operative treatment at Dept. of Orthopaedic Surgery, College of Medicine, Chosun University, from Jan. 1985 to Dec. 1990. The results are summarized as follows; 1. Of 14 cases, there were 12 cases of male and 2 cases of female: male was predominant. Most cases were at their 3rd and 6th decades of age. 2. Traffic accidents were the main causes of injury(11 out of 14 cases.) 3. There were 13 closed fracture and 1 open fracture. 4. In most cases, they accompanied injuries to other vital organ. Among 14 cases, 5 cases accompanied head injury. 5. We treated these fracture by flexible intramedullary nailing in 7 cases, open reduction and internal fixation with plate in 5 cases, locked intramedullary nailing in 2 cases. Bony union was more rapid in the distal fracture than in the proximal fracture. 6. Among 14 cases, primary bone grafting was done in 2 cases. In the group where primary bone grafting had not been done, dealyed union appeared but nonunion was not seen. 7. We could obtain rapid bony union and decreased operation time in the cases which were treated with intramedullary fixation, and thought that intramedullary fixation was a relatively good method in type of this fracture.
Accidents, Traffic ; Bone Transplantation ; Craniocerebral Trauma ; Female ; Fracture Fixation, Intramedullary ; Fractures, Closed ; Fractures, Open ; Hip ; Humans ; Male ; Methods

Anomalous development of the odonteid precess is an uncommon clinical occurence that can seriously impair the integrity af the atlantoaxial articulation. Absence of the odontoid process may be either congenital or acquired, but clinically the etiology is of little importance as the clinical signs and symptoms and the treatment are identical in both. We experienced a case of congenital absence of the odontoid process and good result was obtained from the posterior atlantoaxial fusion with hale-cast.
Odontoid Process

Of 29 scoliotic patients treated by Harrington and Dwyer instrumentation, fourteen patients were taken of preoperative cnrrection by halo-femoral skeletal traction for the last two years from June 1974 to June 1976 at the Department of Orthopedic Surgery, Seoul National University Hospital. The correctability of scoliosis by the use of halo-femoral traction was evaluated with roentgenogram study and the following result was obtained. 1. Of the 14 cases, five cases were male and eight were female, and they were between the age of 13 and 29. 2. The etiology of the 14 scoliosis was idiopathic in three, paralytic in eight, congenital in one, and associated with neurofibromatosis in two. 3. The average initial curve was 108 degress with the flexibility of 32.1% on side bending. 4. The average preoperative curve with halo-femoral traction for one week was 75. 1 (30.5% correction), and the end of two week was 68 (37% correction). 5. The average immediate postoperative curve was 58.5 (46.5% correction). 6. The result of traction in the different etiologic type showes no significant difference.
Female ; Humans ; Male ; Neurofibromatoses ; Orthopedics ; Pliability ; Scoliosis ; Seoul ; Traction

Because most of the hip fracture is endemic to an elderly population, high mortality and morbidity has been encountered due to the fatal complications such as pneumonia, thromboembolism, and decubitus ulceration. So, it is essential to achieve early ambulation with complete reduction by strong interoal fixation divices in order to reduce those complications. As early as 25 years ago McCarroll remarked that this fracture must be considered “unsolved until the incidence of aseptic necrosis and nonunion could be diminished or abolished. Since that time improved reduction method and many new strong fixation divices such as Jewett nail-plate, Massie nail, and compression hip screw have been developed to achieve more accurate reduction and rigid immobilization. The following clinical results were shown by analysis of 117 cases of hip fractures experienced in the Department of Orthopedic Surgery, Seoul National University in the past 5 years from Jan. 1974 to Dec. 1978. 1. Femoral neck fractures were 67 cases and intertrochanteric fractures were 36 cases. 2. The most common cause of hip fractures was slip or fall (70.1%). 3. Incidence of femoral neck fracture was most frequent in the 6th decade, and that of the intertrochanteric fracture was in the 7th decade that is compared with 7th and 8th decade of Caucasian respectively. 4. Old hip fracture more than 3 weeks after trauma was in the 53.6%, and especially that of neck fracture was about 57%. 5. In the classification of the hip fractures, transcervical neck fracture was most frequent (70.1%), and unstable type (79.5%) in the intertrochanteric fracture. 6. Knowles pin was usually used in the stable neck fracture, while compression hip screw used in the unstable neck fracture. 7. Jewett nail-plate was usually used after Dimon-Hughston reduction, and compression hip screw after anatomical reduction in the unstable intertrochanteric fracture. But in the stable fracture either Jewett nail-plate or compression hip screw was usually used after anatomical reduction. 8. Endoprosthesis (26 cases), and total hip replacement arthroplasty (8 cases) were usually carried out in the old femur neck fracture treated by total hip arthroplasty was better than that by endoprosthesis. 9. Avascular necrosis was 13.3%, and nonunion 20% in the femur neck fracture. Nonunion was 12.5%, and delayed union 4.2% in the intertrochanteric fracture. With the above mentioned results, the following conclusion is obtained: 1. It is recommended that open reduction or arthriplasty of the hip should be performed if the closed reduction of the fracture of femoral neck is not adequate. 2. Graden alignment index is a good criteria for adequate reduction of femoral neck fracture. 3. Malunion induces the fate of femoral head to be avascular in the femoral neck fracture. 4. Compression hip screw is a good stabilizer for unstable intertrochanteric fracture. 5. The position of femoral endoprosthesis for delayed or inadequately reduced femoral neck fracture may be replaced by total hip replacement. The clinical result of total hip replacement is far better than that of femoral endoprosthesis In the cases of arthroplasty indication.
Aged ; Arthroplasty ; Arthroplasty, Replacement, Hip ; Classification ; Early Ambulation ; Femoral Neck Fractures ; Femur Neck ; Head ; Hip Fractures ; Hip ; Humans ; Immobilization ; Incidence ; Methods ; Mortality ; Neck ; Necrosis ; Orthopedics ; Pneumonia ; Pressure Ulcer ; Seoul ; Thromboembolism

The injection of paraffin for cosmetic purpose is an illegal method as it evokes late complications such as the development of grauuloma, migration of foreign body, inflammation, ulceration, embolic phenomenon, etc. However, paraffin has been used by some unauthorized people for the augmentation of the soft tissue, i.e. face, breasts, as they can easily reansform the body contour in a short time and paraffin is not expensive to do so. Paraffinoma has been reported frequently as a delayed or late complication of foreign body reaction in the field of plastic surgery. And various mehtods of its surgical treatment also has been a topic of plastic surgeon, as postoperative outcome is not satisfactory. As the nose is located at the center of face, the patients who are suffering from paraffinoma in nose could not conceal their deformed appearance by cosmetics. Therefore the only method of improvement is surgical removal of paraffinoma. Paraffinoma of nose has been removed by transcolumellar, infracartilaginous, intercartilaginous incision. However, complete removal of the foreign material does not seem to be possible, may leave complications such as hematoma and overlying skin necrosis, and the remaining foreign material does not permit symmetric appearance. We experienced excision of paraffinoma by direct incision on nasal dorsum. 3 patients with paraffinoma of nose were successfully treated without any complications by vertical elliptical excision on the dorsum of the nose, and scars on nasal dorsum were acceptable with satisfaction by patients. Therefore, the authors concluded that excision of paraffinoma by direct incision on nasal dorsum is a good method for symmetric resection of foreign material, low risk of complication.
Breast ; Cicatrix ; Foreign Bodies ; Foreign-Body Reaction ; Hematoma ; Humans ; Inflammation ; Necrosis ; Nose ; Paraffin ; Skin ; Surgery, Plastic ; Ulcer

No abstract available.
Occlusive Dressings* ; Skin*

No abstract available.
Cartilage* ; Ear* ; Snails* ; Transplants*

No abstract available.
Stevens-Johnson Syndrome*