1.A Case of Malignant Melanoma of the Conjunctiva.
Hyo Youl KIM ; Young Kyoung CHUN
Journal of the Korean Ophthalmological Society 1978;19(2):227-231
Malignant melanoma of the conjunctiva is rare and occurring usually before 30 years of age. The authors experienced a case of primary malignant melanoma of the conjunctiva of the right eye. This Case of 22 year old patient treated with enucleation and radiation for 22 times with Co60. This patient has been well till now after initial therapy without reccurence. We briefly reviewed the literatures relating to malignant melanoma.
Conjunctiva*
;
Humans
;
Melanoma*
;
Young Adult
2.A Case of Lymphangiectasia of the Vulva.
Ja Kyoung SHIN ; Hun Young JANG ; Chun Wook PARK ; Cheol Heon LEE
Korean Journal of Dermatology 1994;32(4):744-748
Lymphangiectasia is a rsre occurrence, and may be due to an undgrlying disturbance of the lymph flow following surgery or irrediation. We present an unusual case of an extensive lymphangictasia of the vulva following radical abdominal hysterectomy and irradiation for cervical cancer.
Hysterectomy
;
Uterine Cervical Neoplasms
;
Vulva*
3.Surgical management of traumatic duodenal injuries.
Chan Young LEE ; Tae Soo KIM ; Kyoung Sup YOON ; Kee Chun HONG ; Ze Hong WOO
Journal of the Korean Surgical Society 1993;44(6):820-827
No abstract available.
4.The operative management of 8 cases of congenital absence of the vagina.
Hyun Ok KIM ; Kyoung Youl OH ; Young Mi PARK ; Chung Hee CHUN
Korean Journal of Obstetrics and Gynecology 1991;34(10):1470-1476
No abstract available.
Vagina*
5.Spinal Canal Remodelling after Stabilization of Thoracolumbar Burst Fractures.
In Heon PARK ; Kee Byoung LEE ; Kyoung Won SONG ; Jin Young LEE ; Jin Woo CHUN
The Journal of the Korean Orthopaedic Association 1997;32(1):34-39
About half of all burst fractures at the thoracolumbar junction lead to neurological impairment and several clinical series have demonstrated a statistically significant correlation between canal encroachment and neurologic impairment, but not directly related. Spontaneous canal remodelling over time due to bone resorption has been observed in conservatively treated burst fractures. The aim of this study was to measure spinal canal remodelling after stabilization of burst fractures. So, we evaluated 22 cases of surgically stabilized burst fractures of thoracolumbar junction about pre and postoperative spinal canal stenotic ratio and canal remodelling by bone resorption over time. The results were as follows; l. Pedicle splaying increases the spinal canal area and necessitates correction. 2. Patients with neurological deficits had average 53% encroachment and the neurological normal patient had a canal compromise of 33.9%. 3. Postoperatively canal encroachment had decreased to a mean of 17.4% and further reduced by resorption of bony fragment to a mean of 8.3% within 14 months. In conclusions, remodelling of the spinal canal by resorption of encroaching bone fragments is a consistent feature in surgically stabilized thoracolumbar burst fractures and most patients regain their prefracture canal demensions within 14 months.
Bone Resorption
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Humans
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Spinal Canal*
6.A study of cisplatin nephrotoxicity.
Young Hee HWANG ; Kyoung A LEE ; Son Moon SHIN ; Young Hoon PARK ; Jeong Ok HAH ; Chun Dong KIM ; Young Hwan LEE
Yeungnam University Journal of Medicine 1992;9(2):327-333
To evaluate the nephrotoxicity of cisplatin, serum levels of sodium, potassium, chloride, calcium, phosphorous, magnesium, BUN, creatinine and creatinine clearance were measured before and after administration of cisplatin in 18 cases of patients with malignant neoplasm. The results were as follows: 1) Serum calcium, magnesium, potassium and BUN levels were changed after cisplatin administration, but those changes were not statistically significant. 2) The mean value of creatinine clearance was not decreased significantly after treatment with cisplatin. 3) Acute renal failure was developed in one case, and four cases of hypocalcemia, hypomagnesemia were also detected after administration of cisplatin.
Acute Kidney Injury
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Calcium
;
Calcium Chloride
;
Cisplatin*
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Creatinine
;
Humans
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Hypocalcemia
;
Magnesium
;
Potassium
;
Sodium
7.Quantification of endothelin-1 in human umbilical venous endothelial cell culture supernatants of small for gestational age and preeclampsia neonates.
Won Kyoung CHO ; So Young KIM ; Chung Sik CHUN
Korean Journal of Pediatrics 2007;50(12):1194-1199
PURPOSE: It was generally accepted now a days that the pathogenesis of preeclampsia, small for gestational age (SGA), intrauterine growth retardation and fetal origin of adult diseases were related with a endothelial cell dysfunction. The purpose of this study was to know the relation of such diseases by assessing the level of endothelin-1. METHODS: SGA babies, newborns of preeclampsia and normal control mother were included in this study. Isolated endothelial cells were centrifugated and mixed with media in 37, 5% CO2 to obtain confluent monolayer of cultured human umbilical venous endothelial cell (HUVEC). Endothelin-1 levels were determined by Endothelin-1 colorimetric (EIA) Kits. We examined the endothelin-1 level in the HUVEC supernatants from SGA baby, and newborns from preeclampsia as well as normal mother. Also, we compared the endothelin-1 level of cultured normal HUVEC incubated with serum from cord blood of SGA, babies of preeclampsia or normal control mother. RESULTS: The endothelin-1 levels in cultured HUVEC supernatants of three groups showed no significant difference but the endothelin-1 levels of cultured normal HUVEC incubated with serum from preeclampsia mother or SGA mother was significantly higher than those from newborns of control mothers (P<0.05). CONCLUSION: These findings suggest that there may be the factor which affect the endothelin-1 level in serum of cord blood from SGA and preeclampsia.
Adult
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Endothelial Cells*
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Endothelin-1*
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Fetal Blood
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Fetal Growth Retardation
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Gestational Age*
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Humans*
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Infant, Newborn*
;
Mothers
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Pre-Eclampsia*
;
Umbilical Veins
8.A Case of Segmental Neurofibromatosis with Acrochordon-like Clinical Manifestation.
Sin Wook CHUN ; Hyun Ok SON ; Suk Young LEE ; Jong Baik KIM ; Byung In RO ; Han Gyu CHOI ; Han Kyoung CHO
Korean Journal of Dermatology 2016;54(3):218-220
No abstract available.
Neurofibromatoses*
9.The Effect of Lovastatin(Mevacor(R)) in Patients with Hypercholesterolemia.
Su Young LEE ; Chun Suk KYOUNG ; Dong Chan KIM ; Kye Heui LEE ; Sang Joon CHOI ; In SON ; Seong Hoon PARK
Korean Circulation Journal 1991;21(2):328-336
Lovastatin is a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, which catalyzes the conversion of hydroxymethylglutaryl-coenzyme A to mevalonate, anearly and rate-limiting step in the synthesis of cholesterol. We studied the therapeutic effect and safety of lovastatin in 18 patients with nonfamilial primary hypercholesterolemia. Patients received 20mg/day lovastatin therapy as a single evening dose. If the total cholesterol level exceeded 200mg/dl after 2weeks of lovastatin therapy, the dosage of lovastatin was doubled. Mean percent total cholesterol level reductions from baseline were 26.4% and 31.9% after 4, and 8 weeks of lovastatin therapy respectively. Mean percent HDL-cholesterol level increase from baseline were 12% and 13% after 4, and 8 weeks of lovastatin therapy respectively. Adverse effects attributable to lovastatin were mild and temporary and no patient was withdrawn from therapy. We concluded that lovastatin was a well tolerated and effective agent for the treatment of nonfamilial primary hypercholesterolemia. Further studies are needed to establish the long-term safety and effectiveness of this drug.
Cholesterol
;
Coenzyme A
;
Humans
;
Hypercholesterolemia*
;
Lovastatin
;
Mevalonic Acid
;
Oxidoreductases
10.Resistance to Cerebrospinal Fluid Outflow Measured by Bolus Injection Method in Normal Adults.
Eun Young KIM ; Hyun Sun PARK ; Chong Kweon CHUNG ; Tae Kyoung JIN ; Jae Joong KIM ; Hyung Chun PARK
Journal of Korean Neurosurgical Society 2000;29(9):1209-1214
No abstract available.
Adult*
;
Cerebrospinal Fluid*
;
Humans