1.Serous Cystadenoma of the Pancreas: A case report.
Young Kyoung BAE ; Woo Young JANG ; Kyoung Chan CHOI ; Joon Hyuk CHOI ; Won Hee CHOI
Korean Journal of Pathology 1996;30(1):68-71
Serous cystadenoma of the pancreas, also known as microcystic adenoma or glycogen-rich cystadenoma, is an unusually benign tumor. It is usually large and composed microscopically of many small cysts lined by small, cuboidal or flattened cells containing abundant glycogen. It has been suggested that serous cystadenoma probably arise from the ductular cells or centroacinar cells. Herein, we report on a case of serous cystadenoma of the pancreas in a 55-year-old female. The tumor, measuring 13.5x11.5x10.0 cm, was located in the head of the pancreas and the cut surface revealed a sponge-like appearance due to innumerable tiny cysts containing clear serous fluid. Microscopic analysis showed cystic spaces lined by cuboidal cells with intracytoplasmic glycogen.
Female
;
Humans
;
Cysts
;
Adenoma
2.Clinical Study on Massive Fetomaternal Hemorrhage.
Hea Kyoung KIM ; Moon Young CHOI ; Hye Sun YOON ; Bo Young YUN ; Sun Whan BAE ; Dong Woo SON
Korean Journal of Perinatology 2001;12(3):267-273
No abstract available.
Female
;
Fetomaternal Transfusion*
;
Pregnancy
3.Interferon-beta Induced Skin Necrosis.
Gee Young BAE ; Young Il CHUNG ; Kyung II PARK ; Mi Woo LEE ; Kee Chan MOON ; Jai Kyoung KOH
Annals of Dermatology 2003;15(3):119-121
Local cutaneous reactions have been reported at injection sites of interferon therapy, but these are usually erythema or rarely induration. Skin necrosis at the injection site is rare. We describe here a patient with multiple sclerosis who presented with cutaneous necrosis at the injection sites of interferon-β. Biopsy of the necrotic lesion showed dermal vessel thrombosis and complete ischemic coagulative necrosis of epidermis and dermis.
Biopsy
;
Dermis
;
Epidermis
;
Erythema
;
Humans
;
Interferon-beta*
;
Interferons
;
Multiple Sclerosis
;
Necrosis*
;
Skin*
;
Thrombosis
4.Congenital Syphilis: An Uncommon Cause of Gross Hematuria, Skin Rash, and Pneumonia.
Sun Hee SHIM ; Ju Young KIM ; Eu Kyoung LEE ; Kyongwon BANG ; Kyoung Soon CHO ; Juyoung LEE ; Jin Soon SUH ; Joong Hyun BIN ; Hyun Hee KIM ; Won Bae LEE
Korean Journal of Pediatric Infectious Diseases 2014;21(1):65-70
Although congenital syphilis can be prevented with prenatal screening, the disease remains problematic. Currently, there are no cases that describe hematuria and pneumonia related to congenital syphilis. We report a case of congenital syphilis that involved nephrotic syndrome and pneumonia alba in a 22-day-old male infant whose mother did not receive adequate prenatal care. The congenital syphilis diagnosis was confirmed with a serologic test and the patient recovered with penicillin treatment. Clinical findings may be subtle in neonates and delayed recognition occurs frequently, thus complete prenatal screening is critical for congenital syphilis prevention. Immediate serologic testing should be performed to obtain a differential diagnosis if an infant is delivered by a mother that has not received appropriate prenatal examinations.
Diagnosis
;
Diagnosis, Differential
;
Exanthema*
;
Hematuria*
;
Humans
;
Infant
;
Infant, Newborn
;
Male
;
Mothers
;
Nephrotic Syndrome
;
Penicillins
;
Pneumonia*
;
Prenatal Care
;
Prenatal Diagnosis
;
Serologic Tests
;
Syphilis, Congenital*
5.Phytosphingosine-1-phosphate stimulates chemotactic migration of L2071 mouse fibroblasts via pertussis toxin-sensitive G-proteins.
Mi Kyoung KIM ; Kyoung Sun PARK ; Hyuck LEE ; Young Dae KIM ; Jeanho YUN ; Yoe Sik BAE
Experimental & Molecular Medicine 2007;39(2):185-194
Phytosphingosine-1-phosphate (PhS1P) was found to stimulate an intracellular calcium increase via phospholipase C but not pertussis toxin (PTX)- sensitive G-proteins in L2071 mouse fibroblasts. PhS1P also activated ERK and p38 kinase, and these activations by PhS1P were inhibited by PTX. Moreover, PhS1P stimulated the chemotactic migration of L2071 cells via PTX-sensitive Gi protein(s). In addition, the PhS1P-induced chemotactic migration of L2071 cells was also dramatically inhibited by LY294002 and SB203580 (inhibitors of phosphoinositide 3-kinase and p38 kinase, respectively). L2071 cells are known to express four S1P receptors, i.e., S1P1, S1P2, S1P3, and S1P4, and pretreatment with an S1P1 and S1P3 antagonist (VPC 23019) did not affect on PhS1P-induced chemotaxis. This study demonstrates that PhS1P stimulates at least two different signaling cascades, one is a PTX-insensitive but phospholipase C dependent intracellular calcium increase, and the other is a PTX-sensitive chemotactic migration mediated by phosphoinositide 3-kinase and p38 kinase.
1-Phosphatidylinositol 3-Kinase/metabolism
;
Animals
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Calcium Signaling/drug effects
;
Chemotaxis/*drug effects
;
Estrenes/pharmacology
;
Extracellular Signal-Regulated MAP Kinases/metabolism
;
Fibroblasts/*cytology/*drug effects
;
GTP-Binding Proteins/*metabolism
;
Gene Expression Regulation/drug effects
;
Humans
;
Mice
;
Pertussis Toxin/*pharmacology
;
Phosphorylation/drug effects
;
Pyrrolidinones/pharmacology
;
RNA, Messenger/genetics/metabolism
;
Receptors, Lysosphingolipid/genetics/metabolism
;
Sphingosine/*analogs & derivatives/pharmacology
;
p38 Mitogen-Activated Protein Kinases/metabolism
6.A case of Addison's disease with hyperkalemic neuromyopathy.
Kyoung Tae BAE ; Seung Guel LEE ; Young Sung KIM ; Yi Kyoung SUNG ; Houng Gun PARK ; Yong Gu OH ; Se Gil KI
Journal of Korean Society of Endocrinology 1991;6(1):82-87
No abstract available.
Addison Disease*
7.Effects of Self Efficacy Promoting Programs on Self Efficacy, Self Care Behavior and Psychosocial Adaptation in Patients with a Colostomy.
Kyoung Mi KIM ; Eun Seon BAEK ; Nam Hee KANG ; Kyung Eun YOON ; Na Young BAE ; Bo Kyoung CHA
Journal of Korean Academy of Fundamental Nursing 2007;14(3):288-296
PURPOSE: This study was conducted to investigate the effects of self-efficacy promoting program on self-efficacy, self-care behavior and psychosocial adaptation in patients with a colostomy. METHOD: A non-equivalent control group pre test post test design was used. The self efficacy promoting programs was composed of a CD image program based on varicaious experience, education and telephone coaching program based on verbal persuasion, and Stoma care practice, and Self care performance based on performance accomplishment. This study was carried out from July 2, 2005 to April 20, 2006 and 21 patients with a colostomy at one of 2 hospitals participated. Descriptive statistics, chi-square-test, and Mann-whitney U test were used to analyze the data. RESULTS: There were significantly different for specific self efficacy, self care and psychosocial adaptation between the experimental group and control group. CONCLUSION: The self efficacy promoting program for patients with stomas was effective in improving degree of specific self efficacy, self care and psychosocial adaptation.
Colostomy*
;
Education
;
Humans
;
Persuasive Communication
;
Self Care*
;
Self Efficacy*
;
Telephone
8.Detection of Human Papillomavirus DNA in Condylomata Acuminata Patients using Molecular Hybridization.
Kyoung Chan PARK ; Sang Hak LEE ; Yoo Shin LEE ; Young Kee KIM ; Heung Bae PARK ; Jeong Seon SEO
Korean Journal of Dermatology 1989;27(6):660-665
Condylomata acuminata are benign tumors which are mostly venereally transmitted. Common sites were coronal sulcus, perisnal area and prepuce. Among 28 patients, 21 acuminate lesions and 10 papular lesions were found. Twenty eight human genital warts in Korean were analysed by Southern blot hybridization. Sequences related to HPV6/11 are found in 89.3%(25/28) of the condylomata. HPV16 DNA was not found at sll. Subtype of HPV was determined by the restriction pattern of DNA cleaved with PstI restriction enzyme in 7 cases. Six cases of HPV6a and one case of HPV6c are found. The above results suggest that most of condylomata acuminata are caused by HPV6 and HPV11 in Korea.
Blotting, Southern
;
Condylomata Acuminata*
;
DNA*
;
Humans*
;
Korea
9.Clinical Analysis of Early Intervention of Pelviscopic Pus Drainage in the Acute Pelvic Inflammatory Disease.
Min Whan KOH ; Yeun Kyoung BAE ; Yoon Young CHOI
Korean Journal of Obstetrics and Gynecology 2006;49(8):1745-1753
OBJECTIVE: The purpose of this study was to evaluate the clinical efficacy of the early pelviscopic intervention in the acute pelvic inflammatory disease of reproductive aged female. METHODS: A clinical evaluation for 30 women who underwent pelviscopic pus drainage in the pelvic inflammatory disease from September 2001 to December 2004 was done. This study group was compared with the control group that 34 cases of intravenous antibiotics treatment performed and we evaluated the clinical and laboratory findings were recorded for all patients before and after treatment. RESULTS: The mean hospital stay was 7.8 days and 6.9 days respectively (p=0.25). There was statistical difference in regarding to febrile status period, that is febrile status was significantly improved in pelviscopy group. The febrile status of the study group was normalized within postoperative third day except 1 case that postoperative hematoma was formed in cul de sac, but it was not normalized within hospital fifth day in 6 cases (27%) of the control group (p=0.05). But there was no statistical difference between the two groups in regarding to clinical symptom free period except febrile status, WBC count change, and ESR/CRP count change. CONCLUSION: In this study, no significant difference was found between the two groups in regarding to clinical progress. But this study suggested that the early pelviscopic pus drainage was effective first line treatment method for the acute pelvic inflammatory disease with less complications and relatively rapid clinical improvement. However further study with more expanded cases that early pelviscopic intervention was done for the prevention of long term complications of pelvic inflammatory disease will be needed.
Anti-Bacterial Agents
;
Drainage*
;
Early Intervention (Education)*
;
Female
;
Hematoma
;
Humans
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Length of Stay
;
Pelvic Inflammatory Disease*
;
Suppuration*
10.A study on recognition of ABO and Rh blood phenotype in blood donors.
Tae Youn CHOI ; Jung Myeong LEE ; You Kyoung LEE ; Won Bae KIM ; Duk Yong KANG ; Young Chul OH
Korean Journal of Blood Transfusion 1993;4(1):29-34
No abstract available.
Blood Donors*
;
Humans
;
Phenotype*