No abstract available.
Cryptosporidium ; Cyclospora

Juvenile xanthogranuloma is characterized by one, or oftener many, yellow, re3dish yellow, or, brown 4-to-20 mm papules or nodules on the face, scalp, trunk, and mostly, extensor surfaces. It may involve internal organ besides the skin such as eye, gastrointestinal and genitourinary tracts. anthogranuloma in adult is usually solitary and dose not involve organs other than skin, and generally dose ncit resolve without treatment. Histopathologically, characteristic Touton giant cells usually appear numerously. We report a case of juvenile xanthogranulorna which occured on scalp of 49 year-old male showing typical clinical and histopathological findings.
Adult* ; Giant Cells ; Humans ; Male ; Middle Aged ; Scalp* ; Skin ; Xanthogranuloma, Juvenile

No abstract available.
Blood Flow Velocity* ; Humans ; Infant, Newborn ; Infant, Premature*

PURPOSE AND BACKGROUND: Recently several clinical studies suggested that maternal treatment with magnesium sulfate had protective effects against cerebral palsy in premature infants. But previous studies with differing perinatal animal models resulted in inconclusive results with regard to magnesium neuroprotection. Our purpose was to study the neuroprotective effect of magnesium sulfate and optimal dosage on hypoxicischemic brain damage in the newborn rat. METHOD: Seven-day-old rats(n=68) underwent right carotid ligation, followed by 3 hours of hypoxia(8% oxygen in 92% nitrogen). Rats received magnesium sulfate immediately before and again after hypoxia(two doses, 150mg-600mg/kg/dose, n=39), or saline solution(n=29). Severity of injury was assessed 5 days later, by visual evaluation of ipsilateral hemisphere infarction and by measurement of bilateral hemispheric cross sectional areas. RESULTS: Magnesium sulfate pre-treatment reduced the incidence of liquefactive cerebral infarction and atrophy from 80.8% in controls to 22.2% with magnesium sulfate(450 mg/kg/dose, P<0.05). Quantitation of hemispheric areas confirmed these findings. Percent protection based on inter-hemisphere area differences by pre-treatment with magnesium sulfate 450mg/kg/dose ranged from 71.1%(hippocampus) to 90.8%(striatum). However higher dose of magnesium(600mg/kg/dose) did not attenuate hypoxic-ischemic brain injury in the newborn rat but increased mortality. CONCLUSION: Pretreatment of magnesium sulfate has neuroprotective effects against hypoxia-ischemia in the newborn rat and adequate dose of magnesium sufate is important to protect the brain. Magnesium pretreatment may be an effective strategy to decrease the severity of neonatal hypoxic-ischemic brain injury in the adequate dose.
Animals ; Atrophy ; Brain ; Brain Injuries ; Cerebral Infarction ; Cerebral Palsy ; Humans ; Incidence ; Infant, Newborn* ; Infant, Premature ; Infarction ; Ligation ; Magnesium Sulfate* ; Magnesium* ; Models, Animal ; Mortality ; Neuroprotective Agents* ; Oxygen ; Rats*

No abstract available.
Pancreatitis, Chronic*

No abstract available.
Acyclovir* ; Herpes Simplex* ; Simplexvirus*

No abstract available.
Melanoma*

Most obviuos will be the several anatomic differences between the proximal femur of the child and the adult. Fractures of the femoral neck in the children are extremely rsre and usually are the result of severe trauma in 80% of the cases. This accounts for the high frequency of serious associated injuries. In this injury the vascular anatomy changing with age, continuing growth potential and the effect of deforming forces play critical roles in high complication rate and these make treatment difficult. But still any secure guidelines for the treatment of this injury are not established and this is a field which requires more active research and further progress in future. 26 cases treated at Paik Hospital from Jan. 1979 to June 1988 were analyzed in clinical and radiological aspect and the following results were obtained. 1. The commonest type was Cervicotrochanteric fracture in 13 cases(50%),displaced one 21 cases. 2. In Transepiphyseal, Transcervical and Cervicotrochanteric fracture by early reduction and internal fixation, and in Intertrochanteric fracture by conservative treatment we gained satisfactory results. 3. We experienced 2 cases of coxa vara in nonthreaded pin used cases, 4 cases of premature epiphseal closure and 4 cases of avascular necrosis in threaded pin used ones. 4. Complications were developed in 13 cases (50%). These were 5 cases of coxa vara(19.2%) 4 cases of premature epiphyseal closure (15.4%) and 4 cases of avascul necrosis (15.4%). 5. Avascykar necrosis was developed in displaced fracture of Transcervical or Cervico- trochanteric fracture beyond postoperative 1 year. So. we recommend periodic long follow up for evaluation of avascular necrosis.
Adult ; Child ; Clinical Study ; Coxa Vara ; Femur ; Femur Neck ; Follow-Up Studies ; Hip ; Humans ; Necrosis

No abstract available.
Child* ; Humans

PURPOSE: Despite appropriate preventive measures, measles outbreaks occurred in the year of 1989-1990 and 1994 in Korea. Especially, the ratio of young infantile patients below 15 months old was high in those outbreaks, and the reason was, we thought, low serum level of measles specific IgG antibody in pregnant women and low transplacental transfer rate of measles specific IgG antibody to neonate. This study was performed to evaluate the serum level of measles specific IgG antibody in term pregnant women- neonate pairs. METHODS: During Oct. 1. 1994 to Mar. 31. 1995, we collected the 44 paired sera of term pregnant women and their neonate(umbilical cord) in Anam hospital of Korea university medical center and then we measured the measles specific IgG antibody using enzyme linked immunosorbent assay(ELISA: Sigma Diagnostics, SIATM Measles IgG Kit). RESULTS: 1) There was close relationship between maternal and neonatal umbilical cord sera in the level of measles specific IgG antibody(r=0.9288, p<0.001). 2) The mean antibody level of neonates was higher than that of mothers by 1.4 times (p<0.05). 3) The seropositivity of measles specific IgG antibody in term pregnant women was 45.5%(20/44) and that of neonatal umbilical cord was 56.8%(25/44). CONCLUSIONS: Above results demonstrates that the seropositivities and levels of measles specific IgG antibody in term pregnant women and neonates were lower than expected value and partially explain the reasons for the recent measles epidemic in Korea.
Academic Medical Centers ; Disease Outbreaks ; Female ; Humans ; Immunoglobulin G* ; Infant ; Infant, Newborn ; Korea ; Measles* ; Mothers ; Pregnant Women* ; Umbilical Cord*