No abstract available.
Child* ; Humans ; Thyroid Gland* ; Thyroid Nodule*

No abstract available.
Colorectal Neoplasms*

A case of disseminated superficial actinic poroLeratosis affecting 47 years old, house wife, who has been suffering from multiple dark-brownish keratotic papules on the sun-light exposed parts especially face, forearm and dorsa of the both hands with mild itching sensation, is presented. The skin lesions developed about two years ago insidiously and increased size and numberes of the lesion. Her family background suggests autosomal dominant inheritance.
Actins ; Forearm ; Hand ; Humans ; Middle Aged ; Porokeratosis* ; Pruritus ; Sensation ; Skin ; Spouses ; Wills

No abstract available.

BACKGROUND: Limited ischemic tolerance of the lung has remained one of the factors that limits the expansion of pulmonary transplantation as a treatment for end-stage pulmonary disease. Numerous studies on safe long term preservation for lung transplantation has been performed for the purpose of developing ideal preservation solution with extracellular type or intracellular type solutions. In this study, we examined the efficacy of LPDG solution in lung preservation longer than 20 hours by comparison with modified Euro-Collins solution. METHODS: Thirty-four adult mongrel dogs were divided into two groups. Donor lungs were flushed with LPDG solution(n=9) or modified Euro-Collins(MEC) solution(n=8) and stored for 24 hours at 10degrees C. All donor lungs were perfused through the pulmonary arteries with solutions containing prostaglandin E1 and verapamil. Left canine lung allotransplantations wereperformed. Assessment(hemodynamic indices and arterial blood gas analysis) of left implanted lung was made by occluding the right pulmonary artery for ten minutes using pulmonary artery Cuff. Assessment was repeated at the interval of 30 minutes, one hour, and two hours later after reperfusion and then chest X-ray, computed tomogram and lung perfusion scan were obtained. In survival dogs follow-up studies were done with assessment with chest X-ray, computed tomogram of the chest and lung perfusion scan on 7th day postoperatively. After preservation above 20 hours, pathological examinations for ultrastructural findings on right lung were performed in each group. RESULTS: With respect to arterial oxygen tension, LPDG group was superior to MEC but there was no statistical significance for 2 hours after reperfusion. Mean pulmonary artery pressure was less increased(p<0.05) and cardiac output higher(p<0.05) than MEC group until 2 hours after reperfusion. After 2 hours of reperfusion, both groups showed transplanted lung function deteriorated gradually. Perfusion scan of the transplanted lung in LPDG group showed better perfusion rate in immediate post-reperfusion, 3 days and 7 days later respectively but there was no statistical significance and corelation with PaO2 and computed tomographic views. In scanning electron microscopy of pulmonary artery after preservation, LPDG group relatively shows less irregular protrusion of the inner surface of endothelial cell of poulmonary artery than MEC group. CONCLUSIONS: We concluded that LPDG solution can offer safe lung preservation above 20 hours with adequate immunosuppressive therapy and prevention of the infection.
Adult ; Alprostadil ; Animals ; Arteries ; Cardiac Output ; Dogs ; Endothelial Cells ; Follow-Up Studies ; Humans ; Lung Diseases ; Lung Transplantation ; Lung* ; Microscopy, Electron, Scanning ; Organ Preservation ; Oxygen ; Perfusion ; Pulmonary Artery ; Reperfusion ; Thorax ; Tissue Donors ; Verapamil

No abstract available.

No abstract available.
Anencephaly* ; Humans

No abstract available.
Extracorporeal Circulation* ; Heart* ; Potassium* ; Thoracic Surgery*

Extrapyramidal tract motor disorder in calcification of basal ganglia probably occurs when the deposition of acid mucopolysaccharides in the basal ganglia is severe enough to lead to neuronal loss. Basal ganglia calcification has been noted to occur with higher incidence and intensity in encephalitis lethargica, carbon monocide intoxication, anoxia, tuberous sclerosis, toxoplasmosis, hypothyroidism and hypoparathyroidism. The neurologic disorder is frequently reversible with treatment in patients with basal ganglia calcification who have hypoparathy-roidism. We report a patient with idiopathic hypoparathyroidism associated with bilateral calcification of the basal ganglia and athetoid movement. This is the first case report in Korea.
Anoxia ; Athetosis* ; Basal Ganglia* ; Carbon ; Cefonicid ; Encephalitis ; Extrapyramidal Tracts ; Glycosaminoglycans ; Humans ; Hypoparathyroidism* ; Hypothyroidism ; Incidence ; Korea ; Nervous System Diseases ; Neurons ; Toxoplasmosis ; Tuberous Sclerosis

5-Fluorouracil is one of the most commonly used anticancer drug. We report a case of leukoencephalopathy who had received 5-fluorouracil injection following operation of carcinoid tumor in intestine. The case had dementia, dysarthria and gait disturbance. Brain CT showed bilaterally symmetric diffuse low densities in the white matter of cerebrum and cytologic examination of cerebrospinal fluid was negative for malignancy. Discontinuation of 5- fluorouracil injection for several days and then improved the clinical symptoms.
Brain ; Carcinoid Tumor ; Cerebrospinal Fluid ; Cerebrum ; Dementia ; Dysarthria ; Fluorouracil* ; Gait ; Intestines ; Leukoencephalopathies*