No abstract available.
Pregnancy*

Despite the advent of new antimicrobial drugs and mordern imaging techniques, mortality and morbidity of bacterial meningitis remain high. The unfavorable clinical outcomes are due to intracranial complications such as cerebrovascular complications, hydrocephalus, cerebral edema, intracerebral hemorrhage, brain abscess, and convulsion. Prompt identification and treatment of each are essential to mininize unfavorable outcomes. We report two cases of cerebral infarctions complicated by Streptococcus pneumoniae meningitis with a brief review of related literatures.
Brain Abscess ; Brain Edema ; Cerebral Hemorrhage ; Cerebral Infarction* ; Hydrocephalus ; Meningitis, Bacterial ; Meningitis, Pneumococcal* ; Mortality ; Seizures ; Streptococcus pneumoniae* ; Streptococcus* ; Thrombosis

Corneal endothelial cell damage from phacoemulsification has been attributed to mechanical injury caused by surgical manipulation and oxygen free radicals produced by ultrasound. We evaluated role of protective effect in Healon GV and Viscoat on corneal endothelial cell damage during phacoemulsificatin Seventy five eyes underwent phacoemulsigication hrough scleral tunnel incision with posterior chamber lens implantation.: Healon GV, 32 eyes and Viscoat, 43 eyes. We analyzed the corneal endothelial morphology using non-contact specualr microscope and analysis program.The percent loss of corneal endothelial density at 3 months postoperative period was greater in Viscoat(5.87%) than in Healon GV(2.47%),although it was not statistically significant(p>0.1). Coefficient of variation in cell size and hexagonality of the corneal endothelial cells also showed no significant difference between the two groups(p>0.1). In conclusion, Healon GV and Viscoat have similar protective effect on the corneal endothelial cell damage induced by ultrasound during phacoemulsification.
Cell Size ; Corneal Endothelial Cell Loss ; Endothelial Cells ; Free Radicals ; Hyaluronic Acid* ; Oxygen ; Phacoemulsification* ; Postoperative Period ; Ultrasonography

The noncontact autofocus specular microscope with incorporated semiautomated image analyzing program provide a rapid morphometric endothelial analysis. We evaluated the reproducibility of endothelial cell analysis with Konan noncon Robo-ca sp 8000 noncontact specular microscope. Specular microscopic examinations were performed three times each in twenty eyes by two examinations were performed three times one examiner. The difference of mean coefficient of variation of cell density evaluated by two examiners were not statistically significant(4.83% and 3.81, p=0.16). But, mean coefficient of variation of CV(coefficient variation of cell size, poluyimegathim) and hexagonality(pleomorphism) were statistically significantly different between two examiners(12.46%, 17.90%, p=0.04 and 12.30%, 8.40%, p=0.01, respectively). Repeatability evaluated by one examiner in two eyes showed small coefficient of variation of cell density(3.67% & 3.69%) and large coefficient of variation of CV(11.41% & 15.00%) and hexagonality(7.79% & 10.24%). In conclusion, our study has shown that Konan noncon Robo-ca sp 8000 noncontact specular microscope allows accurate estimation of endothelial cell density, But reproducibility of coefficient of variation of cell size and hexagonality analysis were lower than that of cell density analysis.
Cell Count ; Cell Size ; Endothelial Cells*

Deletion of the long arm of chromosome 16 is uncommon. The causes of deletion are two: one is unbalanced translocation and the other is de novo deletion. In our case, a baby was born with characteristics of the deletion of the long arm of chromosome 16: distinct craniofacial dysmorphism, mild hydrocephalus, ventriculoseptal defect, coarctation of aorta, short neck, low set, small and posterially rotated ears and shortening of long bones. High resolution GTG and RBG banding analyses revealed a karyotype: 46, XY, del(16)(q13q22) de novo.
Aortic Coarctation ; Arm ; Chromosomes, Human, Pair 16 ; Ear ; Hydrocephalus ; Karyotype ; Neck

No abstract available.
Ankle* ; Chondromatosis, Synovial*

A case of metastatic malignant melanoma of ovary with malignant melanoma of skin is rare. The tumor was discovered 17months following excisional biopsy of left hand for malignant melanoma of the skin. Primary ovarian malignant melanomas are extremely rare and are thought to originate in teratomas. Ovarian melanoma without evidence of residual teratoma must be considered metastatic even in the absence of a previously identifiable cutaneous or mucocutaneous lesion. We had experienced a case of metastatic malignant melanoma of ovary and presented with a brief review of literature.
Biopsy ; Female ; Hand ; Melanoma* ; Neoplasm Metastasis ; Ovary* ; Skin ; Teratoma

PURPOSE: Iron deficiency anemia is the most common nutrient deficient disorder in infants and young children. Iron deficiency at this age group can cause seroius effects on mental and psychomotor development. The object of this study is to determine the prevalence of iron deficiency and evaluate its relationship with diet during the weaning period. METHODS: We conducted blood tests on 247 healthy, 5-24 months olds, who visited DongBu Municipal Hospital and the local health center for immunizations. One hundred and fifty-two children also had serum iron, TIBC, transferrin-saturation and serum ferritin tested. Mothers of 129 children answered a questionnaire about feeding practices and their children were divided into 3 groups according to age; groupl (5-11 mon.), groupll (12-17 mon.), grouplll (18-24 mon.). RESULTS: Out of the total number of subjects 7.3% (n=18) was anemic (Hbg<11g/dl) and the highest 9.4% was in groupl (5-11 mon.). Among 152, 32.2% (n=49) were in an iron deficient state (ferritin<10ng/ml). In group lll, 57.5% (23/40) were iron deficient. Transferrin saturation<10% was 13.8% (21/152) and ferritin<10ng/ml and/or TS<10% was 37.5%. Analysis of questionnaires is as follows : Total daily caloric intake was 771.9 +/- 264.0 Cal on average. Average daily iron intake was 5.5 +/- 2.7 mg, about half the recommended dietary allowance of 10mg. CONCLUSION: The prevalence of iron deficiency was high (32.9%) in 5-24 months olds. Because iron deficiency without anemia was 27.0%, we recommend to add serum ferritin to routine Hb indices test for iron deficiency evaluation. As average iron intake in weaning period was much less than recommended, it seems appropriate to emphasize feeding iron rich weaning foods.
Anemia ; Anemia, Iron-Deficiency ; Child* ; Diet ; Energy Intake ; Ferritins ; Hematologic Tests ; Hospitals, Municipal ; Humans ; Immunization ; Infant* ; Iron* ; Mothers ; Prevalence ; Surveys and Questionnaires ; Recommended Dietary Allowances ; Transferrin ; Weaning

PURPOSE: Iron deficiency anemia is the most common nutrient deficient disorder in infants and young children. Iron deficiency at this age group can cause seroius effects on mental and psychomotor development. The object of this study is to determine the prevalence of iron deficiency and evaluate its relationship with diet during the weaning period. METHODS: We conducted blood tests on 247 healthy, 5-24 months olds, who visited DongBu Municipal Hospital and the local health center for immunizations. One hundred and fifty-two children also had serum iron, TIBC, transferrin-saturation and serum ferritin tested. Mothers of 129 children answered a questionnaire about feeding practices and their children were divided into 3 groups according to age; groupl (5-11 mon.), groupll (12-17 mon.), grouplll (18-24 mon.). RESULTS: Out of the total number of subjects 7.3% (n=18) was anemic (Hbg<11g/dl) and the highest 9.4% was in groupl (5-11 mon.). Among 152, 32.2% (n=49) were in an iron deficient state (ferritin<10ng/ml). In group lll, 57.5% (23/40) were iron deficient. Transferrin saturation<10% was 13.8% (21/152) and ferritin<10ng/ml and/or TS<10% was 37.5%. Analysis of questionnaires is as follows : Total daily caloric intake was 771.9 +/- 264.0 Cal on average. Average daily iron intake was 5.5 +/- 2.7 mg, about half the recommended dietary allowance of 10mg. CONCLUSION: The prevalence of iron deficiency was high (32.9%) in 5-24 months olds. Because iron deficiency without anemia was 27.0%, we recommend to add serum ferritin to routine Hb indices test for iron deficiency evaluation. As average iron intake in weaning period was much less than recommended, it seems appropriate to emphasize feeding iron rich weaning foods.
Anemia ; Anemia, Iron-Deficiency ; Child* ; Diet ; Energy Intake ; Ferritins ; Hematologic Tests ; Hospitals, Municipal ; Humans ; Immunization ; Infant* ; Iron* ; Mothers ; Prevalence ; Surveys and Questionnaires ; Recommended Dietary Allowances ; Transferrin ; Weaning

PURPOSE: Iron deficiency anemia (IDA) is the most common nutrient deficient disorder in infants and young children. Iron deficiency at this age group can cause serious effects on mental and psychomotor development. We analyzed the hematologic profiles of infants and young children with IDA, comparing them with control group. METHODS: The feeding practices and the iron batteries investigated in 198 anemic patients aged 5 to 36 months who had been brought to Inha General & University Hospital. Control group were 129 healthy infants and children who visited DongBu Municipal Hospital and the local health center for immunizations. They also had hemoglobin concentration (Hb), hematocrit, mean corpuscular volume (MCV), mean corpuscular hemoglobin and red cell distribution width (RDW) tested by the electron counters. Patients with hemoglobin level <11 g/dL who had serum ferritin <10 ng/mL or transferrin saturation <15% were classified as having IDA. RESULTS: Out of the 198 subjects (M:F=1.6:1) with IDA, 81.8% (n=162) was breast feeding more than 6 months. The main causes which they were brought to the clinic were infectious or inflammatory illness, and only 13.1% with IDA were visited for evaluation of pallor or anemia. Correlation between Hb and MCV was much more in IDA group than control group (r=0.709, r=0.368; P<0.001). CONCLUSION: By combining Hb with MCV and RDW as well as iron batteries in screening for iron deficiency and IDA, the accuracy of diagnosis can be increased. We support the use of appropriately iron-fortified formulas or weaning foods, or the routine iron supplement starting at 6 months of age in exclusively breast-fed infants to prevent the iron deficiency.
Anemia ; Anemia, Iron-Deficiency* ; Breast Feeding ; Child* ; Diagnosis ; Erythrocyte Indices ; Erythrocytes* ; Ferritins ; Hematocrit ; Hospitals, Municipal ; Humans ; Immunization ; Infant* ; Iron* ; Mass Screening ; Pallor ; Transferrin ; Weaning