1.Adverse factors of hepatic dysfunction during chemotherapy for childhood malignancy.
Dong Hoon KOH ; Hyung Jong LIM ; Young Kwon CHOI ; Hoon KOOK ; Tae Joo HWANG
Journal of the Korean Cancer Association 1993;25(3):417-422
No abstract available.
Drug Therapy*
2.A Clinical Observation of Paratesticular Tumors.
Chong Kook LIM ; Young Woo KONG
Korean Journal of Urology 1982;23(4):546-549
A clinical observation was made on 19 cases of paratesticular tumors in 19 patients which were neither resolved nor improved with primary medical and conservative treatment in the Department of Urology. Capital Armed Forces General Hospital during the period from March, 1977 to July, 1981. The following results were obtained. 1. The age was ranged from 20 to 45 years old and the most favorable age was in 3rd decade. 2. The main symptoms and signs were palpable mass in 73.1%. 3. Duration of symptoms from onset was over 1 year in 57.9% and under 1 year in 42.1%. The mean duration was 17 months. 4. Organ distribution was 5 cases in epididymis, 5 in spermatic cord and 9 in scrotal tunics. 5. 11 cases arose on the left side, 4 on the right and 4 on the midline. 6. There were benign tumors in 17 (89.5%) and malignant tumors only in 2 (10.5%) of all 19 cases. These malignant lesions were developed in the spermatic cord. 7. The lesions were managed by local resection in 16 cases, orchiectomy in 2 and epididymectomy in 1.
Arm
;
Epididymis
;
Hospitals, General
;
Humans
;
Male
;
Middle Aged
;
Orchiectomy
;
Spermatic Cord
;
Urology
3.A case of asymptomatic cor triatriatum.
Jeong Cheol SEO ; Young Kook LIM ; Gi Wan AN ; Kyoung Sig CHANG ; Soon Pyo HONG
Journal of the Korean Society of Echocardiography 1993;1(2):238-243
No abstract available.
Cor Triatriatum*
5.Effects of Panax ginseng Aqua - acupuncture on Lymphocyte Activities in Glucocorticoid Treated Mice.
Kyung Soo NAM ; Jin Young MOON ; Mi Jung CHOI ; Eun Hong LEE ; Doo Hie KIM ; Jong Kook LIM
Korean Journal of Immunology 1997;19(3):355-362
Panax ginseng (PG) has been used as an important analeptic in traditional medicine. This study was purposed to investigate the effect of PG on immune responses induced by glucocorticoid in mice. PG solution was injected into CV6 and BL23, which are the classical acupuncture points, for 7 days after injection with glucocorticoid. And then B and T cell proliferation and cytolytic activity of natural killer (NK) cells were measured. B cell proliferation by 'H-thymidine incorporation was decreased by about 25% in control group as compared with normal group. However, B cell proliferation was significantly increased 1.8-fold in CV6 group and 2.5-fold in BL23 group as compared with normal group. T cell proliferation by H- thymidine incorporation was decreased by about 15% in control group as compared with normal group. On the other hand, T cell proliferation was significantly increased 1.9-fold in CV6 group and 2.3-fold in BL23 group as cornpared with normal group. Furthermore in purified T cell, the proliferation was furtherly increased rather than in non-purified T cell. The activity of NK cell was remarkably decreased in control group as compared with normal group. However, the activities of NK cells in CV6 and BL23 groups were recovered to the above levels of normal group. On the other hand, the activity of NK cell in the blank locus group was slightly increased compared with control group. However this increasement was not reached the levels of CV6 and BL23 groups. And in the case of purified NK cell, the cytolytic activity of NK cell was respectively increased 1.6-fold in normal group, 1.4-fold in control group, 2.0-fold in blank locus group and 2.0-fold in CV6 group and 1.4-fold in BL23 group as compared to the non-purifed NK cell. These results suggest that PG aqua-acupuncture at CV6 and BL23 may proliferate B and T cells that is suppressed by glucocorticoid, and activate NK cell activity.
Acupuncture Points
;
Acupuncture*
;
Animals
;
Cell Proliferation
;
Hand
;
Killer Cells, Natural
;
Lymphocytes*
;
Medicine, Traditional
;
Mice*
;
Panax*
;
T-Lymphocytes
;
Thymidine
6.Study of Normative Gingival Proportion in Anterior Maxilla.
Min Young CHUNG ; Sung Bin LIM ; Chin Hyung CHUNG
The Journal of the Korean Academy of Periodontology 2004;34(1):19-28
Tooth is the most important element in esthetic consideration on facial area. Tooth alignment which is in harmony with gingiva, lips, and face is also key element. The purpose of this study was to give a clinical discipline for restoration of gingival contour, which contains a ratio of maxillary 6 anterior teeth, research for gingival contour etc., in case of rehabilitation of maxillary anterior teeth. 300 Dankook university dental school students ,who is their twenties and free from periodontitis, participate in this study. The result was from each 70 males and females who had normal occlusion and tooth alignment. Length, width and length/width ratio of maxillary 6 anterior teeth were 0.74-0.81 in male, 0.81-0.84 in female. There was significant difference between male and female. The most deepest position of gingiva in maxillary central incisor and canine was located in distal part of teeth and maxillary lateral incisor was middle portion. In maxillary central incisors, gingival line of the most deepest point appeared significant difference between male and female (p<0.01) whereas there was no difference in lateral incisors and canines. Distance between interdental papilla apex and the most deepest portion appeared significant difference beween male and female. Distance of the deepest positon of gingiva is statistically significant except maxillary central incisors and lateral incisors. Standard deviation and mean of the width of labio-lingual were measured in cervical area and there was a significant difference both male and female.(p<0.01) From this result, we could get the mean of maxillary anterior gingival line and these results have great value in clinical guidance in studying maxillary anterior teeth.
Female
;
Gingiva
;
Humans
;
Incisor
;
Lip
;
Male
;
Maxilla*
;
Periodontitis
;
Rehabilitation
;
Schools, Dental
;
Tooth
7.A Histo-Pathological Study of Effect on Bone Regeneration with Fibrin Adhesive.
Young Woo KO ; Sung Bin LIM ; Chin Hyung CHUNG ; Chong Heon LEE
The Journal of the Korean Academy of Periodontology 2003;33(1):91-102
Several effective treatment methods and materials have been developed for the treatment of furcation involvement. Currently, the combination of guided tissue regeneration (GTR) and bone grafts is the most commonly prescribed method of treating furcation involved defects. But because these cases often present with poor accessibility, placement of the membrane may be difficult and consequently, clinically impractical. In this study, the alveolar bone healing patterns of adult beagle dogs presenting with alveolar bone destruction treated by one of two methods - treatment using solely bone aIlografts (BBP(R)), or treatment using bone allografts (BBP(R)) stabilized by a fibrin adhesive - were comp ared. The effects of the fibrin adhesive on the initial stabilization of the newly formed bone, subsequent regeneration of bone, and the feasibility of the clinical application of the fibrin adhesive were analyzed. The results of the study were as follows: 1. Clinical signs of inflammation at the 4-8 week interval were not observed: but signs of mild inflammation were histologically observed at the 4-week interval. 2. Allografts stabilized by fibrin adhesive showed good bone formation, whereas defects treated with only the allograft material showed incomplete alveolar bone regeneration. 3. Allografts stabilized by fibrin adhesive showed a decrease in the amount old bone with a concurrent increase in the formation of new lamellar bone four weeks post-op, whereas defects treated with only the allograft material showed no new lamellar bone formation at the same interval. 4. In detects treated with only the allograft material, the defective area was filled with connective tissue 8- weeks post-op, whereas fibrin adhesive stabilized allografts showed viable connections between the original bone and the newly formed bone, in addition to neovascularization 8-weeks post-op. The results of this study show that concurrent use of fibrin adhesive materials can stabilize the allograft material and aid in new bone formation Although the stability of fibrin adhesives fall short of the results achievable by GTR membranes, in cases presenting with poor accessibility that contraindicate the use of membranes, fibrin adhesive materials provide a viable and effective alternative to graft stabilization and new bone formation.
Adhesives
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Adult
;
Allografts
;
Animals
;
Bone Regeneration*
;
Connective Tissue
;
Dogs
;
Fibrin Tissue Adhesive*
;
Fibrin*
;
Guided Tissue Regeneration
;
Humans
;
Inflammation
;
Membranes
;
Osteogenesis
;
Regeneration
;
Transplants
8.Clinical Analysis of Infantile Hypertrophic Pyloric Stenosis.
Young Soo HUH ; Myeung Kook LIM ; Kyu Rak KIM
Journal of the Korean Association of Pediatric Surgeons 1998;4(1):39-47
Infantile hypertrophic pyloric stensosis (IHPS), which occurs three of 1,000 live births, is a major cause of nonbilious vomiting of early infancy, but its etiology and pathogenesis are still obscure. The operation of pyloromyotomy as described by Ramstedt in 1912 remains the standard of care for the treatment of IHPS. From January 1990 to July 1997, 64 infants with IHPS were reviewed at department of Pediatric Sursery, Yeungnam University Hospital. The ratio of male to female was 7:1, and the most prevalent age group was between 2 weeks and 8 weeks (81.2%). There were 37 (57.8%) first born babies among total 64 infants. The body weight percentile at admission was lower than 50 percentile in all 64 cases. Onset of symptoms was predominantly between 2week and 4weeks in 23 cases (35.9%). All had a history of nonbilious vomting, generally projectile in nature. In the measured serum electrolytes, hypokalemia was noted in 14 cases (21.9%), hypochloremia was observed in 26 cases (40.6%). In the preoperative ultrasonography, the average muscle thickness, diameter, and length of the pylorus were 6.3mm, 12.3mm, and 17.8mm, respectively. A total of thirteen associated anomalies were noted in twelve patients. All 64 cases were treated with Fredet-Ramstedt pyloromyotomy. There were postoperative complications of wound infection in 3 cases. Intermittent nonprojectile vomiting was presented in 13 cases (20.3%) after operation, but one of them was relieved in 13 days and the rest were relieved within one week by adjustment of oral intake.
Body Weight
;
Electrolytes
;
Female
;
Humans
;
Hypokalemia
;
Infant
;
Live Birth
;
Male
;
Postoperative Complications
;
Pyloric Stenosis, Hypertrophic*
;
Pylorus
;
Standard of Care
;
Ultrasonography
;
Vomiting
;
Wound Infection
9.Cardiovascular Effects of Acute Isovolemic Hemodilution.
Kook Hyun LEE ; Young Jin LIM ; Kwang Won YUM
Korean Journal of Anesthesiology 1991;24(6):1147-1153
Acute normovolemic hemodilution is widely used to conserve blood and to minimize the need for homologous blood transfusion during operation. To evaluate the effects of aeute isovolemic hemodilution on hemodynamics and oxygen transport, pulmonary artery catheter and radial artery catheter were introduced in 8 patients in whom maxillofacial or Wertheim's operation were performed. Blood(estimated from allowable blood loss) was withdrawn from radial artery, and simultaneously replaced by intravenous administration of 5% plasmanate and Hartmann solution. Acute isovolemic hemodilution decreased the hematocrit level from 33.2+/-3.7% to 29.6+/-2.9%. Cardiac output increased significantly, which was associated with decreased systemic vaacular resistance. Oxygen transport and oxygen consumption increased despite a decrease in oxygen carrying capacity. Heart rate, mean arterial perssure, mean pulmonary arterial pressure, central venous pressure, and pulmonary capillary wedge pressure did not change significantly during hemodilution. The results indicate that blood perfusion and oxygenation to tissue were well maintained in the hemodilution of the magnitude used in this study. Therfore it could be concluded that acute isovolemic hemodilution is a safe and relatively simple method of conserving blood and minimizing homologous blood transfusion.
Administration, Intravenous
;
Arterial Pressure
;
Blood Transfusion
;
Cardiac Output
;
Catheters
;
Central Venous Pressure
;
Natural Resources
;
Heart Rate
;
Hematocrit
;
Hemodilution*
;
Hemodynamics
;
Humans
;
Oxygen
;
Oxygen Consumption
;
Perfusion
;
Pulmonary Artery
;
Pulmonary Wedge Pressure
;
Radial Artery
10.Cardiovascular Effects of Acute Isovolemic Hemodilution.
Kook Hyun LEE ; Young Jin LIM ; Kwang Won YUM
Korean Journal of Anesthesiology 1991;24(6):1147-1153
Acute normovolemic hemodilution is widely used to conserve blood and to minimize the need for homologous blood transfusion during operation. To evaluate the effects of aeute isovolemic hemodilution on hemodynamics and oxygen transport, pulmonary artery catheter and radial artery catheter were introduced in 8 patients in whom maxillofacial or Wertheim's operation were performed. Blood(estimated from allowable blood loss) was withdrawn from radial artery, and simultaneously replaced by intravenous administration of 5% plasmanate and Hartmann solution. Acute isovolemic hemodilution decreased the hematocrit level from 33.2+/-3.7% to 29.6+/-2.9%. Cardiac output increased significantly, which was associated with decreased systemic vaacular resistance. Oxygen transport and oxygen consumption increased despite a decrease in oxygen carrying capacity. Heart rate, mean arterial perssure, mean pulmonary arterial pressure, central venous pressure, and pulmonary capillary wedge pressure did not change significantly during hemodilution. The results indicate that blood perfusion and oxygenation to tissue were well maintained in the hemodilution of the magnitude used in this study. Therfore it could be concluded that acute isovolemic hemodilution is a safe and relatively simple method of conserving blood and minimizing homologous blood transfusion.
Administration, Intravenous
;
Arterial Pressure
;
Blood Transfusion
;
Cardiac Output
;
Catheters
;
Central Venous Pressure
;
Natural Resources
;
Heart Rate
;
Hematocrit
;
Hemodilution*
;
Hemodynamics
;
Humans
;
Oxygen
;
Oxygen Consumption
;
Perfusion
;
Pulmonary Artery
;
Pulmonary Wedge Pressure
;
Radial Artery