1.A Clinical Observation of Meconium Aspiration Syndrome.
Chul LEE ; Kook In PARK ; Jean Young LEE ; Dong Gwan HAN
Journal of the Korean Pediatric Society 1984;27(10):958-964
No abstract available.
Infant, Newborn
;
Meconium Aspiration Syndrome*
;
Meconium*
2.A Case of Congenital Mesoblastic Nephroma Detected by Prenatal Ultrasonography in Premature Infant.
Woo Jin KO ; Young Deuk CHOI ; Hee Won SONG ; Seung Kang CHOI ; Kook In PARK ; Kook LEE
Korean Journal of Urology 2000;41(2):341-344
No abstract available.
Humans
;
Infant, Newborn
;
Infant, Premature*
;
Nephroma, Mesoblastic*
;
Ultrasonography, Prenatal*
3.The clinical evaluation of primary gastrointestinal lymphoma.
Myung Hwan KOOK ; Sung Yul LEE ; Young Jin KIM
Journal of the Korean Cancer Association 1993;25(4):468-477
No abstract available.
Lymphoma*
4.The Association between Blood Selenium Level and the Gastric Diseases.
Jong Young LEE ; Doohie KIM ; Seoung Kook PARK
Korean Journal of Preventive Medicine 1988;21(1):172-182
To reveal the association between blood selenium level and the gastric diseases, 180 persons received the gastrofiberscopic examination at the outpatients department of the two university hospitals from July to September 1987, after the exclusion of the persons having the esophageal varix, were randomly selected. Their general characteristics such as age, sex and educational level and so on, were investigated. Five microliter venous blood was collected from each subjects and stored at 0 degrees C in heparinized vaccum tube. The blood selenium level was measured by the flameless atomic absorption spectrophotometry. In the procedure of data analysis, five subjects having benign tumor and anomaly of the stomach, were also excluded. The mean blood selenium levels of the 155.5 microgram/l among gastritis cases, the 154.8 microgram/l gastric ulcer and the 133.0 microgram/l gastric malignancy were significantly lower(p<0.05) than that of the 173.3 microgram/l among normal controls. In men the mean blood selenium levels among gastritis, gastric ulcer and gastric malignancy cases were significantly lower(p<0.05) than that among normal controls. In females, the mean blood selenium levels among gastritis and gastric maligancy cases were significantly lower(P<0.05) than that among normal controls(169.7 microgram/l), buy that among gastric ulcer cases(177.7 microgram/l) was not significantly higher. In the logistic analysis, coefficient of the blood selenium level was -0.0436(p<0.05 ; odds ratio 0.957) for gastritis, -0.0197(p=0.17 ; 0.981) for gastric ulcer, -0.4876(p<0.05 ; 0.614) for gastric malignancy and -0.0411(p<0.05 ; 0.960) for gastric diseases including the gastritis, the gastric ulcer and the gastric malignancy. These data support the hypothesis that the gastric diseases are to be associated with the low selenium level but, for the gastric ulcer, the further research is recommended.
Esophageal and Gastric Varices
;
Female
;
Gastritis
;
Heparin
;
Hospitals, University
;
Humans
;
Male
;
Odds Ratio
;
Outpatients
;
Selenium*
;
Spectrophotometry, Atomic
;
Statistics as Topic
;
Stomach
;
Stomach Diseases*
;
Stomach Ulcer
5.Clinical Application of D-penicillamine and Levamisole in Pheumatoid Arthritis
Eun Woo LEE ; Young Bok JUNG ; Heon Kook KIM
The Journal of the Korean Orthopaedic Association 1983;18(1):81-88
Penicillamine is a component of the penicillin molecule which was identified in the urine of patients with chronic liver disease who were receiving penicillin for the treament of intercurrent infections. Walshe demostrated its effectiveness as copper chelating agent and introduced it into the treatment of Wilson's disease. In addition, it has been shown to be effective in treatment of cystinuria, heavy metal poisoning, and rheumatoid arthritis. Levamisole is a three-ringed molecule which has been used as broad-spectrum antihelminthic drug. Levamisole is capable of T cell immune enhancer and has variable effects on antibody production, Since immune enhancer may affect multiple cell types, either directly or indirectly, and may operate on the adenylcyclase-cAMP-prostaglandin system, the results of treatment may be complex. Levamisole has been shown to be effective in rheumatoid arthritis by several study. We analysed the 29 rheumatoid arthritis patients who were treated at Deartment of Orthopedic Surgery, Chung Ang University Hospital from June, 1978 to June, 1982; among them 17 recieving penicillamine and 12 recieving levamisole. The results were as follows: 1. There were statistically significant improvement in ESR. But there were decrease in mean WBC and platelet counts in patients recieving penicillamine or levamisole. Hemoglobin was not affected. 2. Side effects led to withdrawal of treatment in 8(47%) patients in the penicillamine group and 5(42%) in the levamisole group. 3. In 17 patients having penicillamine treatment, one patient had complete remission(8%).
Antibody Formation
;
Arthritis
;
Arthritis, Rheumatoid
;
Copper
;
Cystinuria
;
Hepatolenticular Degeneration
;
Humans
;
Levamisole
;
Liver Diseases
;
Orthopedics
;
Penicillamine
;
Penicillins
;
Platelet Count
;
Poisoning
6.A Study on Superoxide Radical Formation, Catalase and Superoxide Dismutase Activities in Experimental Cerebral Infarction.
Young Bae LEE ; Seung Weon PARK ; Sang Kook LEE ; Kwan PARK ; Byung Kook MIN ; Jong Sik SUK ; Duck Young CHOI
Journal of Korean Neurosurgical Society 1990;19(8-9):1157-1168
To observe the role of oxygen free radical and enzymatic scavengers in cerebral ischemia, an infarction model was made using transorbital occlusion of the middle cerebral artery in cats. The changes of the superoxide radical production and the activities of superoxide dismutase and catalase were measured. The results were as follows ; 1) The infarction of the left middle cerebral artery(MCA) territory was identified with intracardiac perfusion of a TTC solution after transorbital occlusion. 2) The superoxide radical activities after occlusion of the left MCA were not changed in all groups except for the decrease in 6 hours group of the right side compared to the control group(p<0.05). 3) The Mn-superoxide dismutase activities of the left side in the 12 hours group were significantly higher than those of the right side(p<0.01) and those in the control group(p<0.05). 4) The Cu, Zn-superoxide dismutase activities of the left side in the 3 hours group after occlusion of the left MCA were significantly higher than those in the control group(p<0.05). 5) The catalase activities of the left side in the 3 hours, 6 hours and 12 hours groups after occlusion of the left MCA were significantly higher than those of the right side(p<0.05). 6) The catalase activities of the left side in the 12 hours group after occlusion of the left MCA were significantly higher than those in the control group(p<0.05). The authors suggest that the enzymatic scavangers such as Mn-SOD, Cu, Zn-SOD and catalase increased in the infarcted brain, which means an involvement of free radicals in cerebral infarction.
Animals
;
Brain
;
Brain Ischemia
;
Catalase*
;
Cats
;
Cerebral Infarction*
;
Free Radicals
;
Infarction
;
Middle Cerebral Artery
;
Oxygen
;
Perfusion
;
Superoxide Dismutase*
;
Superoxides*
7.Prognostic Parameters in Moderate or Severe Diffuse Axonal Injury.
Sang Kook LEE ; Kwan PARK ; Young Baeg KIM ; Byung Kook MIN ; Sung Nam HWANG ; Jong Sik SUK ; Duck Young CHOI
Journal of Korean Neurosurgical Society 1990;19(8-9):1123-1128
A retrospective study 40 patients with moderate or severe diffuse axonal injury which is defined as posttraumatic coma for over 24 hours without mass lesions or ischemic insults was conducted in order to identify prognostic parameters. The sign of hypothalamic damage and motor reactivities of 40 patients were reviewed and compared to the outcome. The results were as follows ; 1) The ratio of male to female was about 3 to 1 and the peak incidence was at the first decade. 2) Of abnormal brain stem signs, fever of central origin was observed at the early posttraumatic phase and correlated with nonrecovery of consciousness(P<0.05). 3) Of abnormal brain stem signs, abnormal ADH secretion was significantly correlated with nonrecovery of consciousness(P<0.005). 4) Abnormal motor reactivity to pain was significantly correlated with nonrecovery of consciousness(P<0.005). 5) In the group of recovery of consciousness, initial Glasgow coma scale in 40 patients with moderate or severe DAI was significantly correlated with their outcome(P<0.005).
Brain Stem
;
Coma
;
Consciousness
;
Diffuse Axonal Injury*
;
Female
;
Fever
;
Glasgow Coma Scale
;
Humans
;
Incidence
;
Male
;
Retrospective Studies
8.CT Findings of Paranasal Sinus Osteoma.
Young Uk LEE ; Eun Kyung YOUN ; Sang Gyeong SUH ; Sun Young NA ; Kook Jin LEE
Journal of the Korean Radiological Society 1994;30(1):27-31
PURPOSE: To evaluate the incidence and the site of osteomas and their relation to sinonasal inflammation. MATERIALS AND METHODS: 1578 PNS computed tomography (CT) of patients with symptoms of sinusitis were evaluated and correlation with plain radiographic finding was done. RESULTS: The total incidence of osteomas was 0.82%(13/1578) on plain radiography and 3.29% (52/1578) on CT. Fifty-seven osteomas were found in 1578 PNS CT, including 2 osteomas in 5 cases. The most common site was the ethmoid sinus(54%, 31/57) and the next was the frontal sinus(35%, 20/57) on CT. Forty-five osteomas (78.9%) were associated with the sinonasal inflammatory change. CONCLUSION: The total incidence of osteomas from our results was higher than previous reports. And based on the analysis of CT, the most common site was not the frontal sinus as all the previous reports stated, but the ethmoid sinus, probably by virtue of high resolution of CT and/or higher prevalence of inflammation in the ethmold sinus.
Ethmoid Sinus
;
Frontal Sinus
;
Humans
;
Incidence
;
Inflammation
;
Osteoma*
;
Prevalence
;
Radiography
;
Sinusitis
;
Virtues
9.Congenital cytomegalovirus infection: incidence and clinical outcome.
Young Mo SOHN ; Kook In PARK ; Chul LEE ; Dong Kwan HAN ; Won Young LEE
Journal of the Korean Pediatric Society 1991;34(10):1365-1372
No abstract available.
Cytomegalovirus Infections*
;
Cytomegalovirus*
;
Incidence*
10.A clinical study on the incompetent internal os of the cervix.
Choong Sik HA ; Jin Young PARK ; Tae Bong LEE ; Jae Min LEE ; Kang Kook LEE
Korean Journal of Obstetrics and Gynecology 1993;36(7):1547-1553
No abstract available.
Cervix Uteri*
;
Female