No abstract available.
Drug Therapy* ; Osteoporosis*

No abstract available.

No abstract available.

The purpose of this report is to study further the presence and nature of the serum inhibitory factor against C. albicans and to investigate whether the pregnant mother sera and corresponding the sera of newborn cord blood would have any differend in inhibitory effect compared with normal adult sera. The sei um samples were obtained from 100 normal healthy adults, 50 pregnant mothers, and 5() samples of sera of newborn cord blood respectively. The degree of candidal growth was determined by the change of percent transmission on pectrophotometry of the organism inoculated in nutrient broth during 24-hour incubation. The results obtained were as follows: The sei a from normal healthy adults were found to retain the inhibitory effects on in vit o candidal growth compared with control, The inhibitory effect of pregnant mother or infant cord sera was also demonstrated, but v, as weaker than that of norrnal adult sera. The inhibitory effect of each group sera was reversed nearly to the control level after con..plete saturation with iron. The inhibitory action of normal adults sera in the standard strain of C. albicans was weaker than in the strain from the patient, The nature of the human serum inhibitory factor against in vitro growth of C. albicans seems to be closely related with the unbound iron-binding capacity of transferrin
Adult ; Candida albicans* ; Candida* ; Fetal Blood ; Humans* ; Infant ; Infant, Newborn ; Iron ; Mothers ; Transferrin

No abstract available.

No abstract available.
Skin* ; Tuberculosis, Cutaneous*

No abstract available.
Liver*

BACKGROUND: The diagnostic methods of atherosclerosis before the development of clinical diseases(such as angina pectoris, myocardial infarction, cerebral infarction or peripheral vascular disease) are rather limited. The Russian doctors made the observations through the autopsy studies that there is a good correlation between the degree of atherosclersis or the cholesterol content of the aorta and the cholesterol content of the skin. We tried to investigate whether there is a significant degree of differences in the cholesterol content of the skin between the patietns with atherosclerotic disease(disease group), the patients who have not developed the clinical atheroscleric disease but have risk factors for atherosclerosis(risk group), and the normal control patients(normal group). METHODS: The skin choleterol was extracted from the palm of the hands by the closed contact with the chemicals. RESULTS: 1) The skin cholesterol was 2.77+/-1.08/microg/cm2in the disease group, 2.47+/-1.13microg/cm2in the risk group, and 1.84+/-0.60microg/cm2in the control group, The difference between the disease group and the normal group was significant(p<0.001), but the difference between the disease group and the risk group was not significant. 2) When the skin cholesterol of 2.1microg/cm2was used as a criterion. its sensitivity and specificity to predict either the disease gorup or the risk group was 66.1% and 70.8%. 3) In addition to the skin cholesterol of 2.1microg/cm2or more, if we add a criteria of cholesterol >220mg/dl, or TC/HDL-C ratio >4:1, or Apo B/A ratio >0.9, these separated the normal group from either the disease group or risk group much beter. 4) There was no significant correlation between the skin cholesterol and blood cholesterol. Also there were not any significant correlations between the skin cholesterol and the LDL cholesterol, TC/HDL-C ratio or Apo B/A ratio. CONCLUSION: On the basis of the above mentioned observations made by the Russian doctors and the present data showing significantly higher skin cholesterol level in the disease and risk group compared with normal control group, and little significant correlation between the skin cholesterol and the blood cholesterol level, it is likely that the skin cholesterol can be considered as an independent risk index for the atherosclerotic disease. Measuring the skin cholesterol by extraction of cholesterol from the palms of the hands may help predicting the presence or the risks of the atherosclerotic diseases.
Angina Pectoris ; Aorta ; Atherosclerosis* ; Autopsy ; Cerebral Infarction ; Cholesterol* ; Cholesterol, LDL ; Hand ; Humans ; Myocardial Infarction ; Risk Factors ; Sensitivity and Specificity ; Skin*

Multiple myeloma is considered to be the most common primary malignant bone tumor which has the flat bone as a predilection site in old ages. We experienced a case of an unsual multiple myeloma which formed a huge tumor mass on medial end of left clavicle. The tumor mass together with medial half of the clavicle was excised completely. We have discussed the rationale for the excision of the clavicle.
Clavicle ; Multiple Myeloma

3 cases of giant cell tumor in the distal femur or upper tibia were treated by curettage and acrylic cement packing between October 1978 and May 1981. All were females. The postoperative courses were satisfactory with no recurrence or malignant change for periods of 16 months to 30 months. In one case, acrylic cement reinforced with tantalum wire was used because it is superior to acrylic cement alone in mechanical properties. The adventages of this method are: 1. The cautery effect of setting cement. 2. Avoidence of the need for large quantities of cancellous bone 3. The possibility of incorporating a prosthesis if the lesion is extensive. 4. Rapid mobilization. 5. Ease of early diagnosis of recurrence.
Cautery ; Cementation ; Curettage ; Early Diagnosis ; Female ; Femur ; Giant Cell Tumors ; Giant Cells ; Humans ; Methods ; Prostheses and Implants ; Recurrence ; Tantalum ; Tibia