Majority of the eyes with subfoveal neovascular membrane loss the central vision. We observed two patients who regained significant central vision as the result of the involution of subfoveal neovascularization. On follow-up fundus examination, the subretinal lesions revealed grayish neovascular membranes stained with fluorescein, but did not show the fluid leakage. And subretinal hemorrhage and subretinal fluid were gradually resolved. We assumed that functioning retinal pigment epithelium within the macula and young age were the important factors of the spontaneous improvement of visual outcome.
Fluorescein ; Follow-Up Studies ; Hemorrhage ; Humans ; Membranes ; Retinal Pigment Epithelium ; Subretinal Fluid

Ichthyosis hystrix is a localized variant of Bullous Congenital Ichthyosiform Erythroderma by Broq, and also, localized form of Epidermolytic hyperkeratosis according to Frost and Van Scott's classification of ichthyosi-form dermatoses. Clinically it is generally considered to be widespread systematized epidermal nevus, and demonstrating an autosomal dominant pattem of inheritance, and characterized by verrucous scale at or shortly after birth with particular involve- ment of flexural areas. A case of 21 year old girl with ichthyosis hystrix was reported, The skin lesion showed multiple rice to pea sized linear verrucous papules on left forearm, neck, axilla and upper chest. The skin biopsy was done, the finding shows remarked laminated hyperkeratosis, acanthosis, papillomatosis, and vacuoliization on malpighian layer. Diagnosis was confirmed by clinicaI apperance and histopathologicaI finding. The method of treatment is 0. 05% Vitamin A acid ointment application and show marked improvement.
Axilla ; Biopsy ; Classification ; Diagnosis ; Female ; Forearm ; Humans ; Hyperkeratosis, Epidermolytic ; Ichthyosis* ; Neck ; Nevus ; Papilloma ; Parturition ; Peas ; Porcupines* ; Skin ; Skin Diseases ; Thorax ; Tretinoin* ; Vitamin A* ; Vitamins* ; Wills ; Young Adult

No abstract available.
Retinal Vein Occlusion* ; Retinal Vein* ; Retinaldehyde* ; Vitreous Hemorrhage*

This is a follow-up study of 88 cases of cementless total hip replacement in 77 patients(59 males and 18 female), using AML, PCA and HGP prostheses, performed at the Department of Orthopaedic Surgery, Yonsei University Wonju College of Medicine, between September 1984 and December 1987. The follow-up period ranged from 18 to 56 months, the average being 34 months. The youngest patient was 21 and the oldest one was 79, the average being 47 years. The results were as follows:1. The average of Harris hip score was 89.7 points(Preop, 55.4 pints) at one year for 77 patients and 91.4 points at two years for 68 patients. 2. Radiographic analysis. a. Radiodense line:10 cases(11.4%) around the acetabular cup. 20 cases(22.7%) around the femoral stem. b. Calcar resorption:4 cases with AML stem(4/30), 2 cases with HGP stem(2/7). c. Subsidence:5 cases in PCA group(5/51).d. Radiological loosening:1 cases in PCA stem(1/51). 3. Intraoperative complications a. Femur neck fracture:15 cases(17%);5 cases in PCA group(5/51), 8 cases in AML group (8/31), and 2 cases in HGP group(2/7). b. Lateral collateral ligament tear:One case in PCA prosthesis(1/51). 4. Postoperative complications a. Prosthetic joint dislocation occured in 3 cases:1 case, closed reduction after tight adductor release:2 cases, cup reinsertion due to poor cup position. 5. Heterotopic ossification developed in 5 cases(5.7%) without significant loss of ROM. 6. Postoperative infection developed in 2 cases(2.3%):One superficial and the other deep. All were treated successfully with systemic antibiotics after irrigation and debridement.
Acetabulum ; Anti-Bacterial Agents ; Arthroplasty, Replacement, Hip ; Debridement ; Dislocations ; Femur Neck ; Follow-Up Studies ; Gangwon-do ; Hip ; Humans ; Intraoperative Complications ; Joints ; Lateral Ligament, Ankle ; Male ; Ossification, Heterotopic ; Passive Cutaneous Anaphylaxis ; Postoperative Complications ; Prostheses and Implants

Femoral fracture, dislocation of the hip, or tasumatic amputation of the ipsilateral lower extremity is a rare injury. There has been only a few reports describing their managements. All amputated limbs are vulnerable to fracture, which occur frequently around the hip. Conservative treatments are not always adequate for the managements of fracture and dislocation of the hip and operative procedures are needed in almost patients. Among various operative measures, prosthetic replacement surgery may be indicated in cases of non-united fracture of the femoral neck, avascular necrosis of the femoral head, pathological fracture, or osteoporosis. We performed two cases of total hip replacement for the non-united fracture of the femoral neck(case 1) and the avascular necrosis of the femoral head(case 2) in the ipsilateral lower limb amputees, each. The early results were known to be very satisfactory postoperatively. The first patient was followed for 17 months and the second patient for 22 months. 1. P.C.A. femoral stems and acetabular cups were used without cement in both cases. A operative time was 2 hours and 22 minutes in the first case, 1 hour 45 minutes. in the second case. 2. There were no significant intraoperative or postoperative complications. 3. The functions of each hip were evaluated postoperatively by the method of Jesse and showed satisfactory results. 4. During the follow-up period, roentgenogram showed no significant bony changes around the femoral stems and acetabular cups. 5. The prosthetic replacement is also valuable for the treatment of the fracture-dislocation of the hip in the lower limb amputee.
Acetabulum ; Amputation ; Amputees ; Arthroplasty, Replacement, Hip ; Dislocations ; Extremities ; Femoral Fractures ; Femur Neck ; Follow-Up Studies ; Fractures, Spontaneous ; Head ; Hip ; Humans ; Lower Extremity ; Methods ; Necrosis ; Operative Time ; Osteoporosis ; Postoperative Complications ; Surgical Procedures, Operative

PURPOSE: To report the efficacy of toric orthokeratology lenses in a patient with corneal astigmatism within 1.5 D having difficulty wearing spherical orthokeratology lenses because of limbus-to-limbus corneal astigmatism. CASE SUMMARY: An 11-year-old boy who wanted to wear orthokeratology lenses had a refractive error of -4.75 D sph = -1.00 D cyl 180 in the right eye and -4.50 D sph = -1.25 D cyl 180 in the left eye. The corneal astigmatism was 1.19 D and 1.19 D, respectively, and limbus-to-limbus corneal astigmatism was observed in topography. After wearing spherical orthokeratology lenses, the patient complained of monocular diplopia and both lenses were found to be displaced nasally. Toric orthokeratology lenses were prescribed for centration of lenses and resulted in significant improvement of uncorrected visual acuity of 20/20, refractive error of +0.75 D sph = -0.50 D cyl 170 in the right eye and +0.50 D sph = -0.50 D cyl 160 in the left eye, and centration of lenses for the 12-month follow-up period. CONCLUSIONS: Toric orthokeratology lenses should be considered if spherical orthokeratology lenses are not effective even in patients having less than 1.5 D of corneal astigmatism because of limbus-to-limbus corneal astigmatism.
Astigmatism ; Diplopia ; Eye ; Follow-Up Studies ; Humans ; Refractive Errors ; Visual Acuity

Solitary morphea profunda is a rare form of scleroderma, characterized clinically by a solitary sclerotic plaque, and histologically by marked dermal and subcutaneous fibrosis with an inflammatory infiltrate. We describe another case of this entity presented with an ulcerative, indurated plaque on the left iliac crest, which histologically revealed a focal incidental acantholysis in the overlying epidermis and a marked eosinophilic infiltration through the dermis to the sub-cutaneous tissue.
Acantholysis* ; Dermis ; Eosinophils ; Epidermis ; Fibrosis ; Scleroderma, Localized* ; Ulcer

Even though phototherapy is an effective means of treating hyperbilirubinemia, adequate binocular shields are essential to prevent light hazard of retina during phototherapy. The phototherapy to young albino rabbits was performed under various conditions; exposured for 12, 24, and 48 hours, continuity or intermittence of irradiation, and use of shields. Although there was no definite pathologic change in indirect ophthalmoscopic examination, severe damage was seen at electron microscopic level. In all experimental groups, swelling and edema of photoreceptor were seen. at right after phototherapy. Futhermore, more severe damage was seen in case of intermittent irradiated group and prolong exposed group. In mydriatic eyes, severity of damage was similiar to non mydi iatic eyes, but area of retinal damage was more extensive than non-mydriatic eves.. In control group which was protected by binocular shields during phototherapy, no significant abnormality was found.
Dermatitis, Phototoxic* ; Edema ; Hyperbilirubinemia ; Phototherapy ; Rabbits ; Retina ; Retinaldehyde* ; Telescopes

No abstract available.
Breast* ; Milk, Human*

The authors performed experimental study to produce proliferative vitreoretinopathy by intravitreal injection of homologous fibroblasts in pigmented rabbits. Twenty four eyes of 12 rabbits were divided into control and experimental groups. In experimental group, the eyes were pretreated with expanding gas, perfluoropropane for the vitrectomy. In control group, no such procedure was preceded. In both groups, 5.0×10⁴, 1.0×10⁵ and 1.5×10⁵ cells of homologous fibroblasts were injected into the vitreous cavity. All the eyes were observed regularly with indirect ophthalmoscope followed by fundus photography. Those eyes were enucleated in 1, 2, 4 weeks for the light and electron microscopic studies. The development and severity of the proliferative vitreoretinopathy were correlated with the numbers of the injected fibroblast. This was more pronounced in the experimental group.
Fibroblasts ; Intravitreal Injections ; Ophthalmoscopes ; Photography ; Rabbits ; Vitrectomy ; Vitreoretinopathy, Proliferative*