1.Acrokeratosis Verruciformis of Hopf: Report of a Case.
Young Chan CHOI ; Jung Koo CHO
Korean Journal of Dermatology 1977;15(2):211-215
Acrokeratosis verruciformis is a familial disease characterized by indolent papules resembIing flat warts on the backs of the hands and feet with lesser involvement of volar surfaces, wrists, and ankles. A cas of 42 years old female with acrokeratosis verruciformis is reported. The skin lesions of this patient showed numerous rice to pea sized, flat-topped, round or polygonal, warty papules on the dorsal aspects of the hands and feet and also, pitted keratolysis on both volar surface of the hands. The hitologic findings were those of features of acrokeratosis verruciformis, i.e. the epidermis shows marked hyperkeratosis with slight acanthosis and papillomatosis and circumscribed elevations of the epidermis resembling church spires characteristically.
Adult
;
Ankle
;
Darier Disease*
;
Epidermis
;
Female
;
Foot
;
Hand
;
Humans
;
Papilloma
;
Peas
;
Skin
;
Warts
;
Wrist
2.Two Cases of Eccrine Poroma on the Abdomen.
Hee Jung LEE ; Sung Bin CHO ; Nam Joon CHO ; Young Hun CHO ; Min Geol LEE
Korean Journal of Dermatology 2005;43(12):1660-1662
No abstract available.
3.Clinical analysis of cranioplasty.
Bae Jeong CHO ; Young Jung HWANG ; Sang Hun HAN
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1992;19(4):626-632
No abstract available.
4.Treatment of Moderate Hypercholesterolemia with Lovastatin(Mevacor(R)).
Jung Chaee KANG ; Jeong Gwan CHO ; Min Young CHUNG
Korean Circulation Journal 1991;21(4):786-790
To evaluate the lipid-lowering effect of lovastatin(Mevacor(R)), lovastatin was administered to 38 patients with non-familial hypertcholesterolemia(>220mg/dl). The analysis of the effect was made with 25 patients(58.2+/-7.5 years ; 13 male, 12 female)who had received lovastatin more than 12 weeks. The drug was administered as a single dose with evening meal 20mg at the begining and adding another 20mg if the total cholesterol level was persistently higher than 200mg/dl at the end of each 4 week-period. 1) Total cholesterol level was decreased from 256.6+/-36.9mg/dl to 20932+/-50.1mg/dl at the end of the 4th week, 201.9+/-44.2mg/dl the 8th week and 203.6+/-39.6mg/dl the 12th week (p<0.001), respectively). 2) Triglyceride level was decreased from 196.4+/-104.1mg/dl to 163.4+/-74.4mg/dl at the end of the 4th week(p<0.05) but no significant change at the end of the 8th week showing 169.8+/-73.2mg/dl and 162.7+/-54.8mg/dl the 12th week(p<0.05). 3) High density lipoprotein cholesterol(HDL-C) level was not significantly changed with the drug during the 12 week treatment period. 4) Low density lipoprotein cholesterol(LDL-C) level was decreased remarkably similar to that of total cholesterol. 5) Total cholesterol/HDL-C ratio was decreased from 5.05+/-0.92 to 4.06+/-1.40 at the end of the 4th week(p<0.05), 3.89+/-0.99 the 8th week(p<0.001). 4.20+/-1.10 the 12th week(p<0.01). 6) LDL-C/HDL-C ratio was decreased from 3.24+/-0.94 to 2.43+/-1.21 at the end of the 4th week(p<0.05), 2.23+/-0.86 the 8th week(p<0.001) and 2.54+/-0.98 the 12th week(p<0.05). 7) There was no significant side effect on lovastatin therapy of 12 weeks duration. 8) The laboratory findings including liver function test, uric acid, creatinine, creatine phosphokinase and blood glucose were not changed significantly. From above results we concluded that lovastatin is safe and effective hypocholesterolemic agent in its clinical use.
Blood Glucose
;
Cholesterol
;
Creatine Kinase
;
Creatinine
;
Humans
;
Hypercholesterolemia*
;
Lipoproteins
;
Liver Function Tests
;
Lovastatin
;
Male
;
Meals
;
Triglycerides
;
Uric Acid
5.The Expression of Fas Ligand protein in Keratoconus.
Sun Joo LEE ; Eun Young CHO ; Woo Jung KIM
Journal of the Korean Ophthalmological Society 2000;41(12):2669-2675
No Abstract Available.
Fas Ligand Protein*
;
Keratoconus*
6.HLA-DQA1, HLA-DQB1 & HLA-DRB1 Alleles Distribution in Hepatitis B Vaccine Non-responder.
Il Tae KIM ; Yun Jung CHO ; Young Tae KIM
Korean Journal of Immunology 2000;22(2):81-86
No abstract available.
Alleles*
;
Hepatitis B Vaccines*
;
Hepatitis B*
;
Hepatitis*
;
HLA-DRB1 Chains*
7.The Expression of L-type Calcium Channel mRNA by the Concentrations of Glucose on the Cell Proliferation in Cultured OLETF Rat Aortic Vascular Smooth Muscle Cells.
Hyung Joon YOO ; Young Jung CHO ; Hong Woo NAM
Journal of the Korean Geriatrics Society 2004;8(4):191-195
BACKGROUND: The proliferation of vascular smooth muscle cell(VSMC) is a part of the major pathogenic mechanism for atheroscle- rosis. It has been reported that L-type calcium channel plays a role in the VSMC proliferation in diabetic rats. But there is a little study results about the association between L-type calcium channel and VSMC proliferation by glucose concentrations in culture media. So we examined the association between voltage-dependent L-type calcium channel of VSMCs and the proliferative activity of vascular smooth muscle cells. METHODS: Rat aortic VSMCs were isolated from the aorta of OLETF rat by enzyme method. VSMCs were cultured in various concentrations of glucose(5.5, 25 mM). The VSMCs(1x104 cells in 24-well plates) were incubated in the presence of Bay K 8644 (10-6M) with/without verapamil(10-6M) for 48 hours. Then the proliferation was assessed by MTT(methylthiazole tetrazolium) assay and expression of L-type calcium channel mRNA was measured by RT-PCR. RESULTS: The proliferative ability and the expression of L-type calcium channel of cultured VSMCs were increased dose-dependently by the glucose concentrations(p<0.05). Bay K 8644 enhanced the proliferation of VSMC and verapamil blocked the incremental effects induced by Bay K 8644. CONCLUSION: These results suggest that L-type calcium channel may play a role in VSMC proliferation of OLETF rat.
3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
;
Animals
;
Aorta
;
Calcium Channels, L-Type*
;
Cell Proliferation*
;
Culture Media
;
Glucose*
;
Muscle, Smooth, Vascular*
;
Rats
;
Rats, Inbred OLETF*
;
RNA, Messenger*
;
Verapamil
8.The film thickness and retention of cast crown using adhesive resin cements.
Young Wan JUNG ; Hye Won CHO ; Tai Ho JIN
The Journal of Korean Academy of Prosthodontics 1992;30(3):437-443
No abstract available.
Adhesives*
;
Crowns*
;
Resin Cements*
9.Two Cases of Wernicke's Encephalopathy with Hyperemesis Gravidarum.
Min Young JUNG ; Yong CHO ; Yong Pil KIM
Korean Journal of Obstetrics and Gynecology 1997;40(8):1735-1739
We have experienced two cases of Wernicke's encephalopathy associated with hypere-mesis gravidarum. Delay in it's diagnosis caused a protracted illness and persisting neurol-ogic deficits. Because of its association with chronic alcoholism, possibility of Wernicke's encephalopathy may not be considered in early stage of disease. The clinical feature, the principle of management and the prevention of Wernicke's encephalopathy are discussed.
Alcoholism
;
Diagnosis
;
Female
;
Hyperemesis Gravidarum*
;
Pregnancy
;
Wernicke Encephalopathy*
10.Long term(5 year) results of surgical treatment of stomach cancer.
Chan Young LEE ; Yong Kwan CHO ; Seung Won JUNG
Journal of the Korean Surgical Society 1991;40(5):581-586
No abstract available.
Stomach Neoplasms*
;
Stomach*